Unraveling new features of clindamycin interaction with functional ribosomes and dependence of the drug potency on polyamines

Journal of Biological Chemistry

Volumn 281, Issue 32, 2006, Pages 23103-23110

  Kouvela, Ekaterini C ^a   Petropoulos, Alexandros D ^a   Kalpaxis, Dimitrios L ^a  

^a UNIVERSITY OF PATRAS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; COMPLEXATION; DRUG PRODUCTS; MOLECULAR BIOLOGY; NITROGEN COMPOUNDS; NUCLEIC ACIDS; POLYMERS; RNA;

BIPHASIC KINETICS; CLINDAMYCIN INTERACTION; DRUG POTENCY; POLYAMINES;

ENZYME INHIBITION;

ACETIC ACID DERIVATIVE; CLINDAMYCIN; LINCOMYCIN; N' AZIDOBENZAMIDINOSPERMINE; PEPTIDE; PHENYLALANINE TRANSFER RNA; POLYAMINE; PUROMYCIN; SPERMIDINE; SPERMINE; SPERMINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CROSS LINKING; DRUG ACTIVITY; DRUG BINDING; DRUG EFFECT; DRUG INHIBITION; DRUG POTENCY; DRUG POTENTIATION; DRUG STRUCTURE; ESCHERICHIA COLI; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; RIBOSOME;

ANTI-BACTERIAL AGENTS; AZIDES; CLINDAMYCIN; DRUG INTERACTIONS; ESCHERICHIA COLI; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; PEPTIDES; POLYAMINES; PROTEIN STRUCTURE, TERTIARY; RIBOSOMES; RNA, RIBOSOMAL, 23S; SPERMINE;

ESCHERICHIA COLI;

EID: 33747348387     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M603263200     Document Type: Article

References (44)

1. Spižek, J., and Řezanka, T. (2004) Appl. Microbiol. Biotechnol. 64, 455-464
2. Roberts, M. C. (2004) Mol. Biotechnol. 28, 47-62
3. Verdier, L., Bertho, G., Gharbi-Benarous, J., and Girault, J.-P. (2000) Bioorg. Med. Chem. 8, 1225-1243
4. Douthwaite, S. (1992) Nucleic Acids Res. 20, 4717-4720
5. Kehrenberg, C., Schwarz, S., Jacobsen, L., Hansen, L. H., and Vester, B. (2005) Mol. Microbiol. 57, 1064-1073
6. Schlünzen, F., Zarivach, R., Harms, J., Bashan, A., Tocilj, A., Albrecht, R., Yonath, A., and Franceschi, F. (2001) Nature 413, 814-821
7. Tu, D., Blaha, G., Moore, P. B., and Steitz, T. A. (2005) Cell 121, 257-270
8. Celma, M. L., Monro, R. E., and Vázquez, D. (1971) FEBS Lett. 13, 247-251
9. Cěrná, J., and Rychlík, I. (1972) Biochim. Biophys. Acta 287, 292-300
10. Menninger, J. R., and Coleman, R. A. (1993) Antimicrob. Agents Chemother. 37, 2027-2029
11. Tenson, T., Lovmar, M., and Ehrenberg, M. (2003) J. Mol. Biol. 330, 1005-1014
12. Polacek, N., Gomez, M. J., Ito, K., Xiong, L., Nakamura, Y., and Mankin, A. (2003) Mol. Cell 11, 103-112
13. Champney, W. S., and Tober, C. L. (2000) Curr. Microbiol. 41, 126-135
14. Harris, R. J., and Symons, R. H. (1973) Bioorg. Chem. 2, 266-285
15. Cheney, B. V. (1974) J. Med. Chem. 17, 590-599
16. Fitzhugh, A. L. (1998) Bioorg. Med. Chem. Lett. 8, 87-92
17. Pestka, S. (1972) J. Biol. Chem. 247, 4669-4678
18. Hausner, T.-P., Geigenmüller, U., and Nierhaus, K. H. (1988) J. Biol. Chem. 263, 13103-13111
19. Kallia-Raftopoulos, S., Kalpaxis, D. L., and Coutsogeorgopoulos, C. (1992) Arch. Biochem. Biophys. 298, 332-339
20. Kallia-Raftopoulos, S., Kalpaxis, D. L., and Coutsogeorgopoulos, C. (1994) Mol. Pharmacol. 46, 1009-1014
21. Chang, F. N., and Weisblum, B. (1967) Biochemistry 6, 836-843
22. Vogel, Z., Vogel, T., Zamir, A., and Elson, D. (1971) J. Mol. Biol. 60, 339-346
23. Gaggelli, E., Gaggelli, N., Valensin, D., Valensin, G., Jezowska-Bojczuk, M., and Kozlowski, H. (2002) Inorg. Chem. 41, 1518-1522
24. Bartetzko, A., and Nierhaus, K. H. (1988) Methods Enzymol. 164, 650-658
25. Vaara, M., and Vaara, T. (1983) Antimicrob. Agents Chemother. 24, 107-113
26. Clark, C. T., Swank, R. A., Morgan, J. E., Basu, H., and Matthews, H. R. (1991) Biochemistry 30, 4009-4020
27. Amarantos, I., Xaplanteri, M. A., Choli-Papadopoulou, T., and Kalpaxis, D. L. (2001) Biochemistry 40, 7641-7650
28. Xaplanteri, M. A., Petropoulos, A. D., Dinos, G. P., and Kalpaxis, D. L. (2005) Nucleic Acids Res. 33, 2792-2805
29. Stern, S., Moazed, D., and Noller, H. F. (1988) Methods Enzymol. 164, 481-489
30. Petropoulos, A. D., Xaplanteri, M. A., Dinos, G. P., Wilson, D. N., and Kalpaxis, D. L. (2004) J. Biol. Chem. 279, 26518-26525
31. Synetos, D., and Coutsogeorgopoulos, C. (1987) Biochim. Biophys. Acta 923, 275-285
32. Katunin, V. I., Muth, G. W., Strobel, S. A., Wintermeyer, W., and Rodnina, M. V. (2002) Mol. Cell 10, 339-346
33. Karahalios, P., Mamos, P., Karigiannis, G., and Kalpaxis, D. L. (1998) Eur. J. Biochem. 258, 437-444
34. Segel, I. H. (1993) Enzyme Kinetics, pp. 39-43 and 170-202, John Wiley & Sons, Inc., New York
35. Morrison, J. B., and Walsh, C. T. (1988) Adv. Enzymol. Relat. Areas Mol. Biol. 61, 201-301
36. Polacek, N., Swaney, S., Shinabarger, D., and Mankin, A. S. (2002) Biochemistry 41, 11602-11610
37. Blanchard, S. C., Harold, D. K., Gonzalez, Jr. R. L., Puglisi, J. D., and Chu, S. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 12893-12898
38. Dinos, G., Kalpaxis, D. L., Wilson, D. N., and Nierhaus, K. H. (2005) Nucleic Acids Res. 33, 5291-5296
39. Kalpaxis, D. L., and Coutsogeorgopoulos, C. (1989) Mol. Pharmacol. 36, 615-619
40. Saarma, U., and Remme, J. (1992) Nucleic Acids Res. 20, 3147-3152
41. Athamna, A., Athamna, M., Medlej, B., Bast, D. J., and Rubinstein, E. (2004) J. Antimicrob. Chemother. 53, 609-615
42. Reusser, F. (1975) Antimicrob. Agents Chemother. 7, 32-37
43. Kirillov, S. V., Porse, B. T., and Garrett, R. A. (1999) RNA 5, 1003-1013
44. Kakegawa, T., Guo, Y., Chiba, Y., Miyazaki, T., Nakamura, M., Hirose, S., Canellakis, Z. N., and Igarashi, K. (1991) J. Biochem. 109, 627-631