Malonaldehyde acts as a mitochondrial toxin: Inhibitory effects on respiratory function and enzyme activities in isolated rat liver mitochondria

Life Sciences

Volumn 79, Issue 15, 2006, Pages 1466-1472

  Long, Jiangang ^a,b   Wang, Xuemin ^a,b   Gao, Hongxiang ^a   Liu, Zhi ^a   Liu, Changsheng ^a   Miao, Mingyong ^b   Liu, Jiankang ^a,c,d  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Ketoglutaric dehydrogenase (KGDH); Malate dehydrogenase (MDH); Mitochondrial complex; Mitochondrial respiration; Pyruvate dehydrogenase (PDH)

Indexed keywords

CYTOCHROME C OXIDASE; MALATE DEHYDROGENASE; MALONALDEHYDE; MITOCHONDRIAL ENZYME; OXIDOREDUCTASE; OXOGLUTARATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINIC ACID; UBIQUINOL CYTOCHROME C REDUCTASE;

AGING; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; ENZYME INHIBITION; INHIBITION KINETICS; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; RAT; RESPIRATORY FUNCTION;

AGING; ANIMALS; CELL RESPIRATION; MALONDIALDEHYDE; MITOCHONDRIA, LIVER; MULTIENZYME COMPLEXES; RATS; RATS, SPRAGUE-DAWLEY; TOXINS, BIOLOGICAL;

EID: 33747345594     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.04.024     Document Type: Article

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