Effects of ligands on the mobility of an active-site loop in tyrosine hydroxylase as monitored by fluorescence anisotropy

Biochemistry

Volumn 45, Issue 31, 2006, Pages 9632-9638

  Sura, Giri R ^a   Lasagna, Mauricio ^a   Gawandi, Vijay ^a   Reinhart, Gregory D ^a   Fitzpatrick, Paul F ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANISOTROPY; BINDING ENERGY; CONFORMATIONS; ENZYMES; FLUORESCENCE; MUTAGENESIS; NATURAL FREQUENCIES;

ACTIVE-SITE LOOP; DEAZAPTERIN; DISTRIBUTION OF LIFETIMES; TYROSINE HYDROXYLASE;

MOLECULAR STRUCTURE;

6 METHYLTETRAHYDROPTERIN; AMINO ACID DERIVATIVE; APOENZYME; CHEMICAL AGENT; DEAZAPTERIN; INDOLE DERIVATIVE; LIGAND; PHENYLALANINE; TRYPTOPHAN; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANISOTROPY; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; FLUORESCENCE ANALYSIS; MEASUREMENT; MODEL; PRIORITY JOURNAL; PROTEIN DOMAIN; QUALITATIVE ANALYSIS; SURFACE PROPERTY;

AMINO ACID SUBSTITUTION; ANISOTROPY; BINDING SITES; CLONING, MOLECULAR; FLUORESCENCE; MICROSCOPY, FLUORESCENCE; MUTATION; PHENYLALANINE; PROTEIN CONFORMATION; PTERINS; TRYPTOPHAN; TYROSINE 3-MONOOXYGENASE;

EID: 33747086893     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi060754b     Document Type: Article

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