Chromatographic indexes on immobilized artificial membranes for local anesthetics: Relationships with activity data on closed sodium channels

Pharmaceutical Research

Volumn 14, Issue 12, 1997, Pages 1699-1705

  Barbato, Francesco ^a   La Rotonda, Maria I ^a   Quaglia, Fabiana ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

HPLC; Immobilized artificial membrane (IAM); Local anesthetics; Sodium channels

Indexed keywords

ALPHA DIMETHYLAMINO 2,6 DIMETHYLACETANILIDE; ALPRENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BUFFER; BUPIVACAINE; ETIDOCAINE; LIDOCAINE; LOCAL ANESTHETIC AGENT; MEPIVACAINE; N3,N3 DIETHYLGLYCYLGLYCINE 2,6 XYLIDIDE; OCTANOL; PHOSPHATIDYLCHOLINE; PRILOCAINE; PROCAINE; PROPRANOLOL; SODIUM CHANNEL; TETRACAINE; TOCAINIDE; TRIMECAINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG POTENCY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION; LIPID BILAYER; LIPOPHILICITY; PARTITION COEFFICIENT; PH; PHOSPHOLIPID MEMBRANE; PKA; PREDICTION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ADRENERGIC BETA-ANTAGONISTS; ANESTHETICS, LOCAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROGEN-ION CONCENTRATION; LIPID BILAYERS; MEMBRANES, ARTIFICIAL; PHOSPHOLIPIDS; PROCAINE; SODIUM CHANNELS; TETRACAINE;

EID: 0031414492     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012119527214     Document Type: Article

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