메뉴 건너뛰기




Volumn 28, Issue 2, 2006, Pages 191-200

Aging-related characteristics of growth hormone receptor/binding protein gene-disrupted mice

Author keywords

Aging; Gene disruption; Growth hormone receptor binding protein; Longevity; Mice

Indexed keywords

BINDING PROTEIN; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FOLLITROPIN; GLUCAGON; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GLUCOSE TRANSPORTER 4; GROWTH HORMONE RECEPTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; ISOFLAVONE; LEPTIN; LIOTHYRONINE; LUTEINIZING HORMONE; MANGANESE SUPEROXIDE DISMUTASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PROLACTIN RECEPTOR; RETINOID X RECEPTOR; SOYBEAN PROTEIN; TESTOSTERONE; THYROXINE; TRANSCRIPTION FACTOR FKHR;

EID: 33746892558     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-006-9004-x     Document Type: Review
Times cited : (11)

References (56)
  • 1
    • 12344335482 scopus 로고    scopus 로고
    • Long-lived growth hormone receptor knockout mice: Interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction
    • Al-Regaiey KA, Masternak MM, Bonkowski M, Sun L, Bartke A (2005) Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction. Endocrinology 146:851-860
    • (2005) Endocrinology , vol.146 , pp. 851-860
    • Al-Regaiey, K.A.1    Masternak, M.M.2    Bonkowski, M.3    Sun, L.4    Bartke, A.5
  • 2
    • 0029958128 scopus 로고    scopus 로고
    • Mechanism of signaling by growth hormone receptor
    • Argetsinger LS, Carter-Su C (1996) Mechanism of signaling by growth hormone receptor. Physiol Rev 76:1089-1107
    • (1996) Physiol Rev , vol.76 , pp. 1089-1107
    • Argetsinger, L.S.1    Carter-Su, C.2
  • 4
    • 23844551318 scopus 로고    scopus 로고
    • Minireview: Role of the growth hormone/insulin-like growth factor system in mammalian aging
    • Bartke A (2005) Minireview: role of the growth hormone/insulin-like growth factor system in mammalian aging. Endocrinology 146:3718-3723
    • (2005) Endocrinology , vol.146 , pp. 3718-3723
    • Bartke, A.1
  • 7
    • 4544324120 scopus 로고    scopus 로고
    • Effects of Soy-derived diets on plasma and liver lipids, glucose tolerance, and longevity in normal, long-lived and short-lived mice
    • Bartke A, Peluso MR, Moretz N, Wright C, Bonkowski M, Winters TA et al (2004) Effects of Soy-derived diets on plasma and liver lipids, glucose tolerance, and longevity in normal, long-lived and short-lived mice. Horm Metab Res 36:550-558
    • (2004) Horm Metab Res , vol.36 , pp. 550-558
    • Bartke, A.1    Peluso, M.R.2    Moretz, N.3    Wright, C.4    Bonkowski, M.5    Winters, T.A.6
  • 8
    • 0028913853 scopus 로고
    • Growth hormone binding to a circulating receptor fragment-the concept of receptor shedding and receptor splicing
    • Baumann G (1995) Growth hormone binding to a circulating receptor fragment-the concept of receptor shedding and receptor splicing. Exp Clin Endocrinol Diabetes 103:2-6
    • (1995) Exp Clin Endocrinol Diabetes , vol.103 , pp. 2-6
    • Baumann, G.1
  • 9
    • 0034465691 scopus 로고    scopus 로고
    • Protection against diabetes-induced nephropathy in growth hormone receptor/binding protein gene-disrupted mice
    • Bellush LL, Doublier S, Holland AN, Striker LJ, Striker GE, Kopchick JJ (2000) Protection against diabetes-induced nephropathy in growth hormone receptor/binding protein gene-disrupted mice. Endocrinology 141:163-168
    • (2000) Endocrinology , vol.141 , pp. 163-168
    • Bellush, L.L.1    Doublier, S.2    Holland, A.N.3    Striker, L.J.4    Striker, G.E.5    Kopchick, J.J.6
  • 11
    • 0001988444 scopus 로고
    • Mechanisms of action for somatotropin in growth
    • Campion DR, Hausman GJ, Martin RJ (eds) Plenum, New York
    • Boyd RD, Bauman DE (1989) Mechanisms of action for somatotropin in growth. In: Campion DR, Hausman GJ, Martin RJ (eds) Animal growth regulation. Plenum, New York, pp 257-293
    • (1989) Animal Growth Regulation , pp. 257-293
    • Boyd, R.D.1    Bauman, D.E.2
  • 12
    • 0032958139 scopus 로고    scopus 로고
    • Pituitary and testicular function in growth hormone receptor gene knockout mice
    • Chandrashekar V, Bartke A, Coschigano KT, Kopchick JJ (1999) Pituitary and testicular function in growth hormone receptor gene knockout mice. Endocrinology 140:1082-1088
    • (1999) Endocrinology , vol.140 , pp. 1082-1088
    • Chandrashekar, V.1    Bartke, A.2    Coschigano, K.T.3    Kopchick, J.J.4
  • 14
    • 0028936352 scopus 로고
    • Effects of streptozotocin treatment in growth hormone (GH) and GH antagonist transgenic mice
    • Chen NY, Chen WY, Bellush L, Yang CW, Striker LJ, Striker GE et al (1995) Effects of streptozotocin treatment in growth hormone (GH) and GH antagonist transgenic mice. Endocrinology 136:660-667
    • (1995) Endocrinology , vol.136 , pp. 660-667
    • Chen, N.Y.1    Chen, W.Y.2    Bellush, L.3    Yang, C.W.4    Striker, L.J.5    Striker, G.E.6
  • 16
    • 0034455827 scopus 로고    scopus 로고
    • Assessment of growth parameters and lifespan of GHR/BP gene-disrupted mice
    • Coschigano KT, Clemmons D, Bellush LL, Kopchick JJ (2000) Assessment of growth parameters and lifespan of GHR/BP gene-disrupted mice. Endocrinology 141:2608-2613
    • (2000) Endocrinology , vol.141 , pp. 2608-2613
    • Coschigano, K.T.1    Clemmons, D.2    Bellush, L.L.3    Kopchick, J.J.4
  • 17
    • 33746871241 scopus 로고    scopus 로고
    • Altered growth hormone signaling in two lines of dwarf mice results in diet-induced obesity and hyperinsulinemia but not diabetes
    • Abstract P3-302:561
    • Coschigano KT, Riders ME, Holland AN, Kopchick JJ (2002) Altered growth hormone signaling in two lines of dwarf mice results in diet-induced obesity and hyperinsulinemia but not diabetes. The Endocrine Society 84th Annual Meeting 2002, Abstract P3-302:561
    • (2002) The Endocrine Society 84th Annual Meeting 2002
    • Coschigano, K.T.1    Riders, M.E.2    Holland, A.N.3    Kopchick, J.J.4
  • 18
    • 0041419437 scopus 로고    scopus 로고
    • Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span
    • Coschigano KT, Holland AN, Riders ME, List EO, Flyvbjerg A, Kopchick JJ (2003) Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span. Endocrinology 144:3799-3810
    • (2003) Endocrinology , vol.144 , pp. 3799-3810
    • Coschigano, K.T.1    Holland, A.N.2    Riders, M.E.3    List, E.O.4    Flyvbjerg, A.5    Kopchick, J.J.6
  • 20
    • 13744258936 scopus 로고    scopus 로고
    • The influence of genes on the aging process of mice: A statistical assessment of the genetics of aging
    • de Magalhaes JP, Cabral JA, Magalhaes D (2005) The influence of genes on the aging process of mice: a statistical assessment of the genetics of aging. Genetics 169:265-274
    • (2005) Genetics , vol.169 , pp. 265-274
    • De Magalhaes, J.P.1    Cabral, J.A.2    Magalhaes, D.3
  • 21
    • 0023945744 scopus 로고
    • Progressive glomerulosclerosis develops in transgenic mice chronically expressing growth hormone and growth hormone releasing factor but not in those expressing insulin-like growth factor-1
    • Doi T, Striker LJ, Quaife C, Conti FG, Palmiter R, Behringer R et al (1988) Progressive glomerulosclerosis develops in transgenic mice chronically expressing growth hormone and growth hormone releasing factor but not in those expressing insulin-like growth factor-1. Am J Pathol 131:398-403
    • (1988) Am J Pathol , vol.131 , pp. 398-403
    • Doi, T.1    Striker, L.J.2    Quaife, C.3    Conti, F.G.4    Palmiter, R.5    Behringer, R.6
  • 22
    • 0033835911 scopus 로고    scopus 로고
    • Compensatory alterations of insulin signal transduction in liver of growth hormone receptor knockout mice
    • Dominici FP, Arostegui Diaz G, Bartke A, Kopchick JJ, Turyn D (2000) Compensatory alterations of insulin signal transduction in liver of growth hormone receptor knockout mice. J Endocrinol 166:579-590
    • (2000) J Endocrinol , vol.166 , pp. 579-590
    • Dominici, F.P.1    Arostegui Diaz, G.2    Bartke, A.3    Kopchick, J.J.4    Turyn, D.5
  • 23
    • 33644855561 scopus 로고    scopus 로고
    • Growth hormone receptor deficiency results in blunted ghrelin feeding response, obesity and hypolipidemia in mice
    • First published September 20, doi:10.1152/ajpendo.00181.2005
    • Egecioglu E, Bjursell M, Ljungberg A, Dickson SL, Kopchick JJ, Bergstrom G et al (2006) Growth hormone receptor deficiency results in blunted ghrelin feeding response, obesity and hypolipidemia in mice. Am J Physiol Endocrinol Metab 290:E317-E325 (First published September 20, 2005; doi:10.1152/ajpendo. 00181.2005)
    • (2005) Am J Physiol Endocrinol Metab , vol.290
    • Egecioglu, E.1    Bjursell, M.2    Ljungberg, A.3    Dickson, S.L.4    Kopchick, J.J.5    Bergstrom, G.6
  • 24
    • 18944407852 scopus 로고    scopus 로고
    • Pancreatic islet-specific expression of an insulin-like growth factor-I transgene compensates islet cell growth in growth hormone receptor gene-deficient mice
    • Guo Y, Lu Y, Houle D, Robertson K, Tang Z, Kopchick JJ et al (2005) Pancreatic islet-specific expression of an insulin-like growth factor-I transgene compensates islet cell growth in growth hormone receptor gene-deficient mice. Endocrinology 146:2602-2609
    • (2005) Endocrinology , vol.146 , pp. 2602-2609
    • Guo, Y.1    Lu, Y.2    Houle, D.3    Robertson, K.4    Tang, Z.5    Kopchick, J.J.6
  • 25
    • 0034993409 scopus 로고    scopus 로고
    • Reduced levels of thyroid hormones, insulin, and glucose, and lower body core temperature in the growth hormone receptor/binding protein knockout mouse
    • Hauck SJ, Hunter WS, Danilovich N, Kopchick JJ, Bartke A (2001) Reduced levels of thyroid hormones, insulin, and glucose, and lower body core temperature in the growth hormone receptor/binding protein knockout mouse. Exp Biol Med 226:552-558
    • (2001) Exp Biol Med , vol.226 , pp. 552-558
    • Hauck, S.J.1    Hunter, W.S.2    Danilovich, N.3    Kopchick, J.J.4    Bartke, A.5
  • 26
    • 0036751228 scopus 로고    scopus 로고
    • Antioxidant enzymes, free-radical damage, and response to paraquat in liver and kidney of long-living growth hormone receptor/binding protein gene-disrupted mice
    • Hauck SJ, Aaron JM, Wright C, Kopchick JJ, Bartke A (2002) Antioxidant enzymes, free-radical damage, and response to paraquat in liver and kidney of long-living growth hormone receptor/binding protein gene-disrupted mice. Horm Metab Res 34:481-486
    • (2002) Horm Metab Res , vol.34 , pp. 481-486
    • Hauck, S.J.1    Aaron, J.M.2    Wright, C.3    Kopchick, J.J.4    Bartke, A.5
  • 28
    • 0021894457 scopus 로고
    • Mode of action of pituitary growth hormone on target cells
    • Isaksson OGP, Edén S, Jansson J-O (1985) Mode of action of pituitary growth hormone on target cells. Annu Rev Physiol 47:483-499
    • (1985) Annu Rev Physiol , vol.47 , pp. 483-499
    • Isaksson, O.G.P.1    Edén, S.2    Jansson, J.-O.3
  • 30
    • 0035051811 scopus 로고    scopus 로고
    • Evidence that age-induced decline in memory retention is delayed in growth hormone resistant GH-R-KO (Laron) mice
    • Kinney BA, Coschigano KT, Kopchick JJ, Steger RW, Bartke A (2001) Evidence that age-induced decline in memory retention is delayed in growth hormone resistant GH-R-KO (Laron) mice. Physiol Behav 72:653-660
    • (2001) Physiol Behav , vol.72 , pp. 653-660
    • Kinney, B.A.1    Coschigano, K.T.2    Kopchick, J.J.3    Steger, R.W.4    Bartke, A.5
  • 31
    • 1242292288 scopus 로고    scopus 로고
    • Could a deficiency in growth hormone signaling be beneficial to the aging brain?
    • Kinney-Forshee BA, Kinney NE, Steger RW, Bartke A (2004) Could a deficiency in growth hormone signaling be beneficial to the aging brain? Physiol Behav 80:589-594
    • (2004) Physiol Behav , vol.80 , pp. 589-594
    • Kinney-Forshee, B.A.1    Kinney, N.E.2    Steger, R.W.3    Bartke, A.4
  • 32
    • 0032731982 scopus 로고    scopus 로고
    • Is the Laron mouse an accurate model of Laron syndrome?
    • Kopchick JJ, Laron Z (1999) Is the Laron mouse an accurate model of Laron syndrome? Mol Genet Metab 68:232-236
    • (1999) Mol Genet Metab , vol.68 , pp. 232-236
    • Kopchick, J.J.1    Laron, Z.2
  • 34
    • 4143085927 scopus 로고    scopus 로고
    • Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice
    • Liu JL, Coschigano KT, Robertson K, Lipsett M, Guo Y, Kopchick JJ et al (2004) Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice. Am J Physiol Endocrinol Metab 287:E405-E413
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • Liu, J.L.1    Coschigano, K.T.2    Robertson, K.3    Lipsett, M.4    Guo, Y.5    Kopchick, J.J.6
  • 35
    • 0035175162 scopus 로고    scopus 로고
    • Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth
    • Lupu F, Terwilliger JD, Lee K, Segre GV, Efstratiadis A (2001) Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth. Dev Biol 229:141-162
    • (2001) Dev Biol , vol.229 , pp. 141-162
    • Lupu, F.1    Terwilliger, J.D.2    Lee, K.3    Segre, G.V.4    Efstratiadis, A.5
  • 36
    • 0034033586 scopus 로고    scopus 로고
    • Caloric restriction and aging: An update
    • Masoro EJ (2000) Caloric restriction and aging: an update. Exp Gerontol 35:299-305
    • (2000) Exp Gerontol , vol.35 , pp. 299-305
    • Masoro, E.J.1
  • 37
    • 27744445115 scopus 로고    scopus 로고
    • Caloric restriction results in decreased expression of peroxisome proliferator-activated receptor superfamily in muscle of normal and long-lived growth hormone receptor/binding protein knockout mice
    • Masternak MM, Al-Regaiey KA, Del Rosario Lim MM, Bonkowski MS, Panici JA, Przybylski GK et al (2005a) Caloric restriction results in decreased expression of peroxisome proliferator-activated receptor superfamily in muscle of normal and long-lived growth hormone receptor/binding protein knockout mice. J Gerontol A Biol Sci Med Sci 60:1238-1245
    • (2005) J Gerontol A Biol Sci Med Sci , vol.60 , pp. 1238-1245
    • Masternak, M.M.1    Al-Regaiey, K.A.2    Del Rosario Lim, M.M.3    Bonkowski, M.S.4    Panici, J.A.5    Przybylski, G.K.6
  • 38
    • 24644504840 scopus 로고    scopus 로고
    • Effects of caloric restriction on insulin pathway gene expression in the skeletal muscle and liver of normal and long-lived GHR-KO mice
    • Masternak MM, Al-Regaiey KA, Del Rosario Lim MM, Jimenez-Ortega V, Panici JA, Bonkowski MS et al (2005b) Effects of caloric restriction on insulin pathway gene expression in the skeletal muscle and liver of normal and long-lived GHR-KO mice. Exp Gerontol 40:679-684
    • (2005) Exp Gerontol , vol.40 , pp. 679-684
    • Masternak, M.M.1    Al-Regaiey, K.A.2    Del Rosario Lim, M.M.3    Jimenez-Ortega, V.4    Panici, J.A.5    Bonkowski, M.S.6
  • 39
    • 0036843071 scopus 로고    scopus 로고
    • Gene expression patterns in calorically restricted mice: Partial overlap with long-lived mutant mice
    • Miller RA, Chang Y, Galecki AT, Al-Regaiey K, Kopchick JJ, Bartke A (2002) Gene expression patterns in calorically restricted mice: partial overlap with long-lived mutant mice. Mol Endocrinol 16:2657-2666
    • (2002) Mol Endocrinol , vol.16 , pp. 2657-2666
    • Miller, R.A.1    Chang, Y.2    Galecki, A.T.3    Al-Regaiey, K.4    Kopchick, J.J.5    Bartke, A.6
  • 40
    • 33746924985 scopus 로고    scopus 로고
    • Abnormal liver lipids in mice with a targeted disruption of the growth hormone receptor/binding protein (GHR/BP) gene
    • Ng VL, Coschigano K, Kopchick JJ, Bezerra JA, Howles P, Yeh YY et al (1999) Abnormal liver lipids in mice with a targeted disruption of the growth hormone receptor/binding protein (GHR/BP) gene. Gastroenterology 116:G2753
    • (1999) Gastroenterology , vol.116
    • Ng, V.L.1    Coschigano, K.2    Kopchick, J.J.3    Bezerra, J.A.4    Howles, P.5    Yeh, Y.Y.6
  • 41
    • 0029829259 scopus 로고    scopus 로고
    • Somatostatin, growth hormone, insulin-like growth factor-1, and diabetes: Friends or foes?
    • Orskov H (1996) Somatostatin, growth hormone, insulin-like growth factor-1, and diabetes: friends or foes? Metabolism 45[Suppl 1]:91-95
    • (1996) Metabolism , vol.45 , Issue.1 SUPPL. , pp. 91-95
    • Orskov, H.1
  • 43
    • 0030895378 scopus 로고    scopus 로고
    • Insulin exposure and aging theory
    • Parr T (1997) Insulin exposure and aging theory. Gerontology 43:182-200
    • (1997) Gerontology , vol.43 , pp. 182-200
    • Parr, T.1
  • 44
    • 13944282128 scopus 로고    scopus 로고
    • Sex and death: What is the connection?
    • Partridge L, Gems D, Withers DJ (2005) Sex and death: what is the connection? Cell 120:461-472
    • (2005) Cell , vol.120 , pp. 461-472
    • Partridge, L.1    Gems, D.2    Withers, D.J.3
  • 45
    • 0024507405 scopus 로고
    • Histopathology associated with elevated levels of growth hormone and insulin-like growth factor I in transgenic mice
    • Quaife CJ, Mathews LS, Pinkert CA, Hammer RE, Brinster RL, Palmiter RD (1989) Histopathology associated with elevated levels of growth hormone and insulin-like growth factor I in transgenic mice. Endocrinology 124:40-48
    • (1989) Endocrinology , vol.124 , pp. 40-48
    • Quaife, C.J.1    Mathews, L.S.2    Pinkert, C.A.3    Hammer, R.E.4    Brinster, R.L.5    Palmiter, R.D.6
  • 46
    • 0033756507 scopus 로고    scopus 로고
    • Bone homeostasis in growth hormone receptor-null mice is restored by IGF-1but independent of stat5
    • Sims NA, Clement-Lacroix P, Da Ponte F, Bouali Y, Binart N, Moriggl R et al (2000) Bone homeostasis in growth hormone receptor-null mice is restored by IGF-1but independent of stat5. J Clin Invest 106:1095-1103
    • (2000) J Clin Invest , vol.106 , pp. 1095-1103
    • Sims, N.A.1    Clement-Lacroix, P.2    Da Ponte, F.3    Bouali, Y.4    Binart, N.5    Moriggl, R.6
  • 47
    • 0342470958 scopus 로고    scopus 로고
    • Disproportional skeletal growth and markedly decreased bone mineral content in growth hormone receptor -/- mice
    • Sjögren K, Bohlooly YM, Olsson B, Coschigano K, Törnell J, Mohan S et al (2000) Disproportional skeletal growth and markedly decreased bone mineral content in growth hormone receptor -/- mice. Biochem Biophys Res Commun 267:603-608
    • (2000) Biochem Biophys Res Commun , vol.267 , pp. 603-608
    • Sjögren, K.1    Bohlooly, Y.M.2    Olsson, B.3    Coschigano, K.4    Törnell, J.5    Mohan, S.6
  • 48
    • 0030863133 scopus 로고    scopus 로고
    • Essential role of growth hormone in ischemia-induced retinal neovascularization
    • Smith LE, Kopchick JJ, Chen W, Knapp J, Kinose F, Daley D et al (1997) Essential role of growth hormone in ischemia-induced retinal neovascularization. Science 276:1706-1709
    • (1997) Science , vol.276 , pp. 1706-1709
    • Smith, L.E.1    Kopchick, J.J.2    Chen, W.3    Knapp, J.4    Kinose, F.5    Daley, D.6
  • 51
    • 27844525887 scopus 로고    scopus 로고
    • Disruption of growth hormone signaling retards early stages of prostate carcinogenesis in the c3(1)/t antigen mouse
    • Wang Z, Prins GS, Coschigano KT, Kopchick JJ, Green JE, Ray VH et al (2005) Disruption of growth hormone signaling retards early stages of prostate carcinogenesis in the c3(1)/t antigen mouse. Endocrinology 146:5188-5196
    • (2005) Endocrinology , vol.146 , pp. 5188-5196
    • Wang, Z.1    Prins, G.S.2    Coschigano, K.T.3    Kopchick, J.J.4    Green, J.E.5    Ray, V.H.6
  • 52
    • 23944433155 scopus 로고    scopus 로고
    • Age-related cataract progression in five mouse models for anti-oxidant protection or hormonal influence
    • Wolf N, Penn P, Pendergrass W, Van Remmen H, Bartke A, Rabinovitch P et al (2005) Age-related cataract progression in five mouse models for anti-oxidant protection or hormonal influence. Exp Eye Res 81:276-285
    • (2005) Exp Eye Res , vol.81 , pp. 276-285
    • Wolf, N.1    Penn, P.2    Pendergrass, W.3    Van Remmen, H.4    Bartke, A.5    Rabinovitch, P.6
  • 53
    • 0027314158 scopus 로고
    • Glomerulosclerosis in mice transgenic for native or mutated bovine growth hormone gene
    • Yang CW, Striker LJ, Kopchick JJ, Chen WY, Pesce CM, Peten EP et al (1993) Glomerulosclerosis in mice transgenic for native or mutated bovine growth hormone gene. Kidney Int 43 [Suppl 39]:S90-S94
    • (1993) Kidney Int , vol.43 , Issue.39 SUPPL.
    • Yang, C.W.1    Striker, L.J.2    Kopchick, J.J.3    Chen, W.Y.4    Pesce, C.M.5    Peten, E.P.6
  • 54
    • 0036786108 scopus 로고    scopus 로고
    • Impact of growth hormone resistance on female reproductive function: New insights from growth hormone receptor knockout mice
    • Zaczek D, Hammond J, Suen L, Wandji S, Service D, Bartke A et al (2002) Impact of growth hormone resistance on female reproductive function: new insights from growth hormone receptor knockout mice. Biol Reprod 67:1115-1124
    • (2002) Biol Reprod , vol.67 , pp. 1115-1124
    • Zaczek, D.1    Hammond, J.2    Suen, L.3    Wandji, S.4    Service, D.5    Bartke, A.6
  • 56
    • 12644257576 scopus 로고    scopus 로고
    • A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)
    • USA
    • Zhou Y, Xu BC, Maheshwari HG, He L, Reed M, Lozykowski M et al (1997) A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse). Proc Natl Acad Sci USA 94:13215-13220
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 13215-13220
    • Zhou, Y.1    Xu, B.C.2    Maheshwari, H.G.3    He, L.4    Reed, M.5    Lozykowski, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.