The role of junctional adhesion molecule C (JAM-C) in acute pancreatitis

Journal of Pathology

Volumn 209, Issue 4, 2006, Pages 540-548

  Vonlaufen, A ^a   Aurrand Lions, M ^b   Pastor, C M ^a   Lamagna, C ^b   Hadengue, A ^a   Imhof, Beat A ^b   Frossard, J L ^a  

^a University Hospital   (Switzerland)

^b UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Acute pancreatitis; Inflammatory infiltrate; JAM C; Transgenic mice

Indexed keywords

ALPHA INTEGRIN; AMYLASE; ANGIOPOIETIN RECEPTOR; CELL ADHESION MOLECULE; CERULETIDE; CYTOKINE; JUNCTIONAL ADHESION MOLECULE C; MONOCLONAL ANTIBODY; REAGENT; UNCLASSIFIED DRUG;

ACINAR CELL; ACUTE PANCREATITIS; AMYLASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG TARGETING; ENDOTHELIUM CELL; ENZYME RELEASE; GENE OVEREXPRESSION; INFLAMMATORY CELL; LEUKOCYTE MIGRATION; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TISSUE INJURY; TRANSGENIC MOUSE;

ACUTE DISEASE; AMYLASES; ANIMALS; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; CAERULEIN; CELL ADHESION MOLECULES; CHEMOTAXIS, LEUKOCYTE; EDEMA; ENDOTHELIAL CELLS; IMMUNOGLOBULINS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, ANIMAL; NECROSIS; PANCREAS; PANCREATITIS;

EID: 33746885909     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2007     Document Type: Article

References (37)

1. Steer ML (ed). Etiology and Pathophysiology of Acute Pancreatitis. Raven Press: New York, 1993.
2. Frossard JL, Pastor CM. Experimental acute pancreatitis: new insights into the pathophysiology. Front Biosci 2002;7:d275-d287.
3. Ohshio G, Saluja A, Steer ML. Effects of short-term pancreatic duct obstruction in rats. Gastroenterology 1991;100:196-202.
4. Saluja A, Saluja M, Villa A, Leli U, Rutledge P, Meldolesi J, et al. Pancreatic duct obstruction in rabbits causes digestive zymogen and lysosomal enzyme colocalization. J Clin Invest 1989;84:1260-1266.
5. Saluja A, Hashimoto S, Saluja M, Powers RE, Meldolesi J, Steer ML. Subcellular redistribution of lysosomal enzymes during caerulein-induced pancreatitis. Am J Physiol 1987;253:G508-G516.
6. Grady T, Liang P, Ernst SA, Logsdon CD. Chemokine gene expression in rat pancreatic acinar cells is an early event associated with acute pancreatitis. Gastroenterology 1997;113:1966-1975.
7. Gukovsky I, Gukovskaya AS, Blinman TA, Zaninovic V, Pandol SJ. Early NF-kappaB activation is associated with hormone-induced pancreatitis. Am J Physiol 1998;275:G1402-G1414.
8. Gukovskaya AS, Gukovsky I, Zaninovic V, Song M, Sandoval D, Gukovsky S, et al. Pancreatic acinar cells produce, release, and respond to tumor necrosis factor-alpha. Role in regulating cell death and pancreatitis. J Clin Invest 1997;100:1853-1862.
9. Sandoval D, Gukovskaya A, Reavey P, Gukovsky S, Sisk A, Braquet P, et al. The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis. Gastroenterology 1996;111:1081-1091.
10. Gukovskaya AS, Vaquero E, Zaninovic V, Gorelick FS, Lusis AJ, Brennan ML, et al. Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis. Gastroenterology 2002;122:974-984.
11. Mayerle J, Schnekenburger J, Kruger B, Kellermann J, Ruthenburger M, Weiss FU, et al. Extracellular cleavage of E-cadherin by leukocyte elastase during acute experimental pancreatitis in rats. Gastroenterology 2005;129:1251-1267.
12. Frossard JL, Saluja A, Bhagat L, Lee HS, Bhatia M, Hofbauer B, et al. The role of intercellular adhesion molecule 1 and neutrophils in acute pancreatitis and pancreatitis-associated lung injury. Gastroenterology 1999;116:694-701.
13. Rau B, Paszkowski A, Esber S, Gansauge F, Poch B, Beget HG, et al. Anti-ICAM-1 antibody modulates late onset of acinar cell apoptosis and early necrosis in taurocholate-induced experimental acute pancreatitis. Pancreas 2001;23:80-88.
14. Schenkel AR, Mamdouh Z, Chen X, Liebman RM, Muller WA. CD99 plays a major role in the migration of monocytes through endothelial junctions. Nature Immunol 2002;3:143-150.
15. Muller WA, Weigl SA, Deng X, Phillips DM. PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med 1993;178:449-460.
16. Aurrand-Lions M, Duncan L, Ballestrem C, Imhof BA. JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cells. J Biol Chem 2001;276:2733-2741.
17. Shaw SK, Bamba PS, Perkins BN, Luscinskas FW. Real-time imaging of vascular endothelial-cadherin during leukocyte transmigration across endothelium. J Immunol 2001;167:2323-2330.
18. Martin-Padura I, Lostaglio S, Schneemann M, Williams L, Romano M, Fruscella P, et al. Junctional adhesion molecule, a novel member of the immunoglobulin superfamily J Cell Biol 1998;142:117-127.
19. Ostermann G, Weber KS, Zernecke A, Schroder A, Weber C. JAM-1 is a ligand of the beta(2) integrin LFA-I involved in transendothelial migration of leukocytes. Nature Immunol 2002;3:151-158.
20. Muller WA. Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response. Trends Immunol 2003;24:327-334.
21. Aurrand-Lions M, Johnson-Leger C, Wong C, Du Pasquier L, Imhof BA. Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members. Blood 2001;98:3699-3707.
22. Zen K, Babbin BA, Liu Y, Whelan JB, Nusrat A, Parkos CA. JAM-C is a component of desmosomes and a ligand for CD11b/CD18-mediated neutrophil transepithelial migration. Mol Biol Cell 2004;15:3926-3937.
23. Arrate MP, Rodriguez SM, Tran TM, Brock TA, Cunningham SA. Cloning of human junctional adhesion molecule 3 (JAM3) and its identification as the JAM2 counter-receptor. J Biol Chem 2001;276:45826-45832.
24. Ludwig RJ, Zollner TM, Santoso S, Hardt K, Gille J, Baatz H, et al. Junctional adhesion molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammation. J Invest Dermatol 2005;125:969-976.
25. Santoso S, Sachs UJ, Kroll H, Linder M, Ruf A, Preissner KT, et al. The junctional adhesion molecule 3 (JAM-3) on human platelets is a counter-receptor for the leukocyte integrin Mac-1. J Exp Med 2002;196:679-691.
26. Chavakis T, Keiper T, Matz-Westphal R, Hersemeyer K, Sachs UJ, Nawroth PP, et al. The junctional adhesion molecule-C promotes neutrophil transendothelial migration in vitro and in vivo. J Biol Chem 2004;279:55602-55608.
27. Johnson-Leger CA, Aurrand-Lions M, Beltraminelli N, Fasel N, Imhof BA. Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration. Blood 2002;100:2479-2486.
28. Schlaeger TM, Bartunkova S, Lawitts JA, Teichmann G, Risau W, Deutsch U, et al. Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice. Proc Natl Acad Sci U S A 1997;94:3058-3063.
29. Aurrand-Lions M, Lamagna C, Dangerfield JP, Wang S, Herrera P, Nourshargh S, et al. Junctional adhesion molecule-C regulates the early influx of leukocytes into tissues during inflammation. J Immunol 2005;174:6406-6415.
30. Lampel M, Kem HF. Acute interstitial pancreatitis in the rat induced by excessive doses of a pancreatic secretagogue. Virchows Arch A Pathol Anat Histol 1977;373:97-117.
31. Leser HG, Gross V, Scheibenbogen C, Heinisch A, Salm R, Lausen M, et al. Elevation of serum interleukin-6 concentration precedes acute-phase response and reflects severity in acute pancreatitis. Gastroenterology 1991;101:782-785.
32. McKay CJ, Gallagher G, Brooks B, Imrie CW, Baxter JN. Increased monocyte cytokine production in association with systemic complications in acute pancreatitis. Br J Surg 1996;83:919-923.
33. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 1994;76:301-314.
34. Imhof BA, Dunon D. Leukocyte migration and adhesion. Adv Immunol 1995;58:345-416.
35. Feng D, Nagy JA, Pyne K, Dvorak HF, Dvorak AM. Neutrophils emigrate from venules by a transendothelial cell pathway in response to FMLP. J Exp Med 1998;187:903-915.
36. Shimada M, Andoh A, Hata K, Tasaki K, Araki Y, Fujiyama Y, et al. IL-6 secretion by human pancreatic periacinar myofibroblasts in response to inflammatory mediators. J Immunol 2002;168:861-868.
37. Suzuki S, Miyasaka K, Jimi A, Funakoshi A. Induction of acute pancreatitis by cerulein in human IL-6 gene transgenic mice. Pancreas 2000;21:86-92.