Eicosapentaenoic acid prevents endothelin-1-induced cardiomyocyte hypertrophy in vitro through the suppression of TGF-β1 and phosphorylated JNK

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 291, Issue 2, 2006, Pages

  Shimojo, Nobutake ^a   Jesmin, Subrina ^a   Zaedi, Sohel ^a   Maeda, Seiji ^a   Soma, Masaaki ^b   Aonuma, Kazutaka ^a   Yamaguchi, Iwao ^a   Miyauchi, Takashi ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b Mochida Pharmaceutical   (Japan)

Author keywords

c Jun NH 2 terminal kinase; Neonatal cardiomyocyte; Transforming growth factor 1

Indexed keywords

ALPHA ACTININ; CYTOSKELETON PROTEIN; ENDOTHELIN 1; ICOSAPENTAENOIC ACID; MESSENGER RNA; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; CELL ISOLATION; HEART HYPERTROPHY; HEART PROTECTION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, NEWBORN; ATRIAL NATRIURETIC FACTOR; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CARDIOMEGALY; CELL SIZE; CELLS, CULTURED; EICOSAPENTAENOIC ACID; ENDOTHELIN-1; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOHISTOCHEMISTRY; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MYOCYTES, CARDIAC; NATRIURETIC PEPTIDE, BRAIN; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 33746849258     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01365.2005     Document Type: Article

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