Synthesis and binding studies of epibatidine analogues as ligands for the nicotinic acetylcholine receptors

European Journal of Medicinal Chemistry

Volumn 41, Issue 5, 2006, Pages 640-650

  Mu, Linjing ^a   Drandarov, Konstantin ^a   Bisson, William H ^a   Schibig, Anita ^a   Wirz, Christa ^a   Schubiger, P August ^a   Westera, Gerrit ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Affinity; Epibatidine analogues; Nicotinic acetylcholine receptors (nAChRs)

Indexed keywords

BICYCLO COMPOUND; EPIBATIDINE; NICOTINIC RECEPTOR; FUSED HETEROCYCLIC RINGS; LIGAND; PYRIDINE DERIVATIVE;

AFFINITY LABELING; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG SAFETY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; MOUSE; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; POSITRON EMISSION TOMOGRAPHY; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; METABOLISM; NERVE CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR STRUCTURE; NEURONS; PYRIDINES; RATS; RECEPTORS, NICOTINIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33746759019     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2006.01.015     Document Type: Article

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