SCOPUS 정보 검색 플랫폼

Journal of Computer-Aided Molecular Design

Volumn 15, Issue 3, 2001, Pages 247-258

An improved nicotinic pharmacophore and a stereoselective CoMFA-model for nicotinic agonists acting at the central nicotinic acetylcholine receptors labelled by [3H]-N-methylcarbamylcholine

(5) Tonder, J E a Olesen, P H a Hansen, J B a Begtrup, M b Pettersson, I a

a NOVO NORDISK A S (Denmark)

b UNIVERSITY OF COPENHAGEN (Denmark)

Author keywords

3D QSAR; CoMFA model; Nicotinic agonists; Pharmacophore model

Indexed keywords

COMPUTATIONAL CHEMISTRY; PHARMACODYNAMICS; STEREOSELECTIVITY;

3D-QSAR; ACETYLCHOLINE RECEPTOR; COMFA MODEL; NICOTINIC ACETYLCHOLINE; NICOTINIC AGONISTS; NITROGEN ATOM; PHARMACOPHORE MODELS; PHARMACOPHORES; PROTONATED NITROGEN; STEREO-SELECTIVE;

HYDROGEN BONDS;

3 METHYL 5 (1 METHYL 2 PYRROLIDINYL)ISOXAZOLE; ACETYLCHOLINE; ALIPHATIC COMPOUND; ALPHA BUNGAROTOXIN; ANATOXIN A; AROMATIC COMPOUND; AZETIDINE DERIVATIVE; CARBONYL DERIVATIVE; CHLORINE DERIVATIVE; CHOLINERGIC RECEPTOR; CYTISINE; ENT 5; EPIBATIDINE; IMIDACLOPRID; INSECTICIDE; LIGAND; METHYL IODIDE; METHYLCARBACHOL; NICOTINE; NICOTINE DERIVATIVE; NICOTINIC AGENT; NICOTINIC RECEPTOR; NITROGEN; OXADIAZOLE DERIVATIVE; OXYGEN; PYRAZINE DERIVATIVE; PYRIDINE DERIVATIVE; PYRROLIDINE DERIVATIVE; TRITIUM; UB 165; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL TISSUE; ARTICLE; ATOM; CHEMICAL BINDING; CHEMICAL COMPOSITION; COMPUTER AIDED DESIGN; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG BINDING SITE; DRUG STRUCTURE; ELECTRICITY; HYDROGEN BOND; ISOTOPE LABELING; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

EID: 0035102669 PISSN: 0920654X EISSN: None Source Type: Journal
DOI: 10.1023/A:1008140021426 Document Type: Article

Times cited : (47)

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