The G2 checkpoint activated by DNA damage does not prevent genome instability in plant cells

Biological Research

Volumn 39, Issue 2, 2006, Pages 331-340

  Carballo, Jesús A ^a,b   Pincheira, Juana ^c   de la Torre, Consuelo ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c UNIVERSITY OF CHILE   (Chile)

Author keywords

Apoptosis; Checkpoint adaptation; G2 DNA damage checkpoint; Genome instability; X rays

Indexed keywords

CAFFEINE; PLANT DNA;

ANAPHASE; APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL NUCLEUS; CHROMATID; CHROMOSOME BREAKAGE; CONTROLLED STUDY; DNA CONTENT; DNA DAMAGE; DNA REPAIR; DOSE RESPONSE; EVOLUTIONARY ADAPTATION; FLOW CYTOMETRY; GENOMIC INSTABILITY; MERISTEM; MITOSIS; MITOSIS INDEX; NICK END LABELING; NONHUMAN; ONION; PLANT CELL; RADIATION DOSE; ROOT GROWTH; X IRRADIATION;

ALLIUM CEPA;

EID: 33746607214     PISSN: 07169760     EISSN: 07176287     Source Type: Journal    
DOI: 10.4067/S0716-97602006000200015     Document Type: Article

References (24)

1. ANDREASSEN PR, MARGOLIS RL (1992) 2-Aminopurine overrides multiple cell cycle checkpoints in BHK cells. Proc Natl Acad Sci USA 89: 2272-2276
2. BENNET CB, SNIPE JR, WESTMORELAND JW, RESNIK MA (2001) SIR functions are required for the toleration of an unrepaired double-strand break in a dispensable yeast chromosome. Mol Cell Biol 21: 5359-5373
3. BLASINA A, BRENDAN DP, GAETAN AT, MCGOWAN CH (1999) Caffeine inhibits the checkpoint kinase ATM. Curr Biol 9: 1135-1138
4. BODDY MN, FURNARI B, MONDESERT O, RUSSELL P (1998) Replication checkpoint enforced by kinases Cds1 and Chk1. Science 280: 909-912
5. FALCK J, MAILAND N, SYLJUASEN RG, BARTEK J, LUKAS J (2001) The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 410: 842-847
6. GIMÉNEZ-ABIÁN MI, DE LA TORRE C, LÓPEZ-SÁEZ JF (1987) Growth and cell proliferation in Allium roots at different oxygen tensions. Environ Exp Bot 27: 233-237
7. HARPER JW, ELLEDGE SJ (1996) Cdk inhibitors in development and cancer. Curr Opin Genet Dev 6: 56-64
8. MARCELAIN K, DE LA TORRE C, GONZÁLEZ P, PINCHEIRA J (2005) Roles of nibrin and ATM/ATR kinases on the G2 checkpoint under endogenous or radio-induced DNA damage. Biol Res 38: 179-185
9. MCCLINTOCK B (1984) The significance of responses of the genome to challenge. Science 226: 792-801
10. MEIJER L (1996) Chemical inhibitors of cyclin-dependent kinases. Prog Cell Cycle Res 1, 351-363
11. NURSE P (1990) Universal control mechanism regulating onset of M-phase. Nature 344: 503-508
12. O'CONNELL MJ, CIMPRICH KA (2005) G2 damage checkpoints: What is the turn-on? J Cell Sci 118: 1-6
13. PAULOVICH AG, TOCZYSKI DP, HARTWELL LH (1997) When checkpoints fail. Cell 88: 315-321
14. PELAYO HR, LASTRES P, DE LA TORRE C (2001) Replication and G2 checkpoints: Their response to caffeine. Planta 212: 444-453
15. PÉREZ-TALAVERA S, CARBALLO JA, DE LA TORRE C (2003) Lack of mitotic delays at the onset of proliferation in dormant root primordia challenged by ionizing radiation. Biol Plantarum 46: 383-387
16. REICHHELD JP, VERNOUX T, LARDON F, VAN MONTAGU M, INZÉ D (1999) Specific checkpoint regulate plant cell cycle progression in response to oxidative stress. Plant J 17: 647-656
17. SÁNCHEZ Y, WONG C, THOMA RS, RICHMAN R, WU Z, PIWNICA-WORMS H, ELLEDGE SJ (1997) Conservation of the Chk1 checkpoint kinase in mammals: Linkage of DNA damage to Cdk regulation through Cdc25. Science 277: 1497-1501
18. SARKARIA JN, BUSBY EC, TIBBETS RS, ROOS P, TAYA Y, KARNITZ LM, ABRAHAM RT (1999) Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Res 59: 4375-4382
19. TUTEJA N, SINGH MB, MISRA MK, BHALLA PL, TUTEJA R (2001) Molecular mechanisms of DNA damage and repair: Progress in plants. Crit Rev Biochem Mol Biol 36: 337-397
20. WALWORTH N, DAVEY S, BEACH D (1993) Fission yeast kinase links the rad checkpoint pathway to cdc2. Nature 363: 368-371
21. WANG JYJ (2001) DNA damage and apoptosis (Editorial). Cell Death Diff 8: 1047-1048
22. WEINERT TA, HARTWELL LH (1988) The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science 241: 317-322
23. WEINGARTNER M, PELAYO HR, BINAROVA P, ZWERGER K, MELIKANT B, DE LA TORRE C, HEBERLE-BORS E, BÖGRE L (2003) A plant Cyclin B2 is degraded early in mitosis and its ectopic expression shortens G2-phase and alleviates the DNA damage checkpoint. J Cell Sci 126: 487-498
24. XIAO Z, CHEN Z, GUNASEKERA AH, SOWIN TJ, ROSENBERG SH, FESIK S, ZHANG H (2003) Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA damaging agents. J Biol Chem 278: 21767-21773