Histidine-conjugated poly(amino acid) derivatives for the novel endosomolytic delivery carrier of doxorubicin

Journal of Controlled Release

Volumn 114, Issue 1, 2006, Pages 60-68

  Yang, Seung Rim ^a   Lee, Hyun Jin ^a   Kim, Jong Duk ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Doxorubicin; Endosomolytic synthetic polymer; Histidine; Intracellular delivery; Poly(amino acids)

Indexed keywords

ELECTROSTATICS; GRAFTING (CHEMICAL); IONIZATION; MICROSCOPIC EXAMINATION; MOLECULAR STRUCTURE; PH EFFECTS;

DOXORUBICIN; ENDOSOMOLYTIC SYNTHETIC POLYMER; HISTIDINE; INTRACELLULAR DELIVERY; POLYAMINO ACIDS;

ORGANIC POLYMERS;

AMINO ACID DERIVATIVE; DOXORUBICIN; HISTIDINE DERIVATIVE; POLY(2 HYDROXYETHYLASPARTAMIDE); UNCLASSIFIED DRUG;

ARTICLE; CELLULAR DISTRIBUTION; CHEMICAL INTERACTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; ELECTRICITY; ENDOSOME; HUMAN; HUMAN CELL; HYDROPHOBICITY; IONIZATION; PH MEASUREMENT; PRIORITY JOURNAL; SURFACE PROPERTY;

AMINES; BUFFERS; CELL SURVIVAL; DOXORUBICIN; DRUG CARRIERS; ELECTROSTATICS; ENDOCYTOSIS; ENDOSOMES; HELA CELLS; HISTIDINE; HUMANS; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MICROSCOPY, CONFOCAL; MOLECULAR STRUCTURE; PARTICLE SIZE; PEPTIDES; SPECTRUM ANALYSIS; SURFACE PROPERTIES;

EID: 33746584827     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.05.016     Document Type: Article

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