Structural basis of the cross-reaction between an antibody to the Trypanosoma cruzi ribosomal P2β protein and the human β1 adrenergic receptor

FASEB Journal

Volumn 20, Issue 9, 2006, Pages 1396-1406

  Smulski, C ^a   Labovsky, V ^a   Levy, G ^a   Hontebeyrie, M ^b   Hoebeke, J ^c   Levin, M J ^a,d  

^a INSTITUTO DE INVESTIGACIONES EN INGENIERÍA GENÉTICA Y BIOLOGÍA MOLECULAR   (Argentina)

^b INSTITUT PASTEUR   (France)

^c INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^d INSTITUT COCHIN   (France)

Author keywords

Paratope epitope modeling; Ribosomal P proteins; Single chain Fv fragments (scFv)

Indexed keywords

ASPARAGINE DERIVATIVE; BETA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR ANTIBODY; CYCLIC AMP; DIMER; EPITOPE; GLUTAMINYLASPARTYLASPARTYLASPARTYLMETHIONYLGLYCYLPHENYLALANYLGLYCYLLEUCYLPHENYLALANINE; GLUTAMINYLSERYLASPARTYLGLUTAMINYLALANYLARGINYLARGINYLCYSTEINYLTYROSYLASPARAGINE; ISOPRENALINE; MONOCLONAL ANTIBODY; MONOMER; P2BETA PROTEIN; P2BETA PROTEIN ANTIBODY; PHENYLALANINE DERIVATIVE; PROTEIN ANTIBODY; PROTOZOON ANTIBODY; R13 MONOCLONAL ANTIBODY; RECEPTOR ANTIBODY; RHODOPSIN; RIBOSOME PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; TRYPANOSOMA CRUZI ANTIBODY; IMMUNOGLOBULIN FRAGMENT; PEPTIDE FRAGMENT; PHOSPHOPROTEIN; PHOSPHOPROTEIN P2, RIBOSOMAL; PRIMER DNA; PROTOZOAL PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ANTIGEN ANTIBODY REACTION; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CHAGAS DISEASE; CHO CELL; CONTROLLED STUDY; CROSS REACTION; EXTRACELLULAR MATRIX; HEART BEAT; IMMUNOCHEMISTRY; IN VIVO STUDY; KINETICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; RAT; THREE DIMENSIONAL IMAGING; TRYPANOSOMA CRUZI; ANIMAL; CHEMISTRY; GENETICS; HAMSTER; HEART RATE; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION;

TRYPANOSOMA CRUZI;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, PROTOZOAN; BASE SEQUENCE; CHAGAS DISEASE; CHO CELLS; CRICETINAE; CROSS REACTIONS; DNA PRIMERS; HEART RATE; HUMANS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PHOSPHOPROTEINS; POLYMERASE CHAIN REACTION; PROTOZOAN PROTEINS; RATS; RECEPTORS, ADRENERGIC, BETA-1; RIBOSOMAL PROTEINS; TRYPANOSOMA CRUZI;

EID: 33746472057     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.05-5699com     Document Type: Article

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