Single-chain Fv fragments of anti-neuraminidase antibody NC10 containing five- and ten-residue linkers form dimers and with zero-residue linker a trimer

Protein Engineering

Volumn 10, Issue 4, 1997, Pages 423-433

  Kortt, Alexander A ^a   Lah, Maria ^a,e   Oddie, Geoffrey W ^a   Gruen, Clem L ^a   Burns, John E ^a   Pearce, Lesley A ^a   Atwell, John L ^a   McCoy, Airlie J ^a   Howlett, Geoffrey J ^b   Metzger, Dennis W ^c   Webster, Robert G ^d   Hudson, Peter J ^a  

^a CSIRO   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c MEDICAL COLLEGE OF OHIO   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^e Zenyth Therapeutics Limited Australia   (Australia)

Author keywords

Antibody; Complexes with antigens; Dimers; Shorter linkers; Single chain Fvs; Trimers

Indexed keywords

IMMUNOGLOBULIN FC FRAGMENT; SIALIDASE; TETRAMER;

ANTIBODY COMBINING SITE; ARTICLE; BINDING AFFINITY; BIOSENSOR; IMMUNOGLOBULIN STRUCTURE; NONHUMAN; PRIORITY JOURNAL; SENSOR; SURFACE PROPERTY;

EID: 0030953197     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/10.4.423     Document Type: Article

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