-
1
-
-
0034551747
-
Signaling mechanism in the induction of apoptosis by thrombin in human tumor cells
-
Ahmad, R., Menezes, J. and Ahmad, A. (2000). Signaling mechanism in the induction of apoptosis by thrombin in human tumor cells. Blood 96, 4001.
-
(2000)
Blood
, vol.96
, pp. 4001
-
-
Ahmad, R.1
Menezes, J.2
Ahmad, A.3
-
2
-
-
0032518291
-
Nerve growth factor promotes activation of the alpha, beta and gamma isoforms of protein kinase B in PC12 pheochromocytoma cells
-
Andjelkovic, M., Suidan, H. S., Meier, R., Frech, M., Alessi, D. R. and Hemmings, B. A. (1998). Nerve growth factor promotes activation of the alpha, beta and gamma isoforms of protein kinase B in PC12 pheochromocytoma cells. Eur. J. Biochem. 251, 195-200.
-
(1998)
Eur. J. Biochem.
, vol.251
, pp. 195-200
-
-
Andjelkovic, M.1
Suidan, H.S.2
Meier, R.3
Frech, M.4
Alessi, D.R.5
Hemmings, B.A.6
-
3
-
-
0033970561
-
Identification of thrombin receptors in rat brain capillary endothelial cells
-
Bartha, K., Domotor, E., Lanza, F, Adam-Vizi, V. and Machovich, R. (2000). Identification of thrombin receptors in rat brain capillary endothelial cells. J. Cereb. Blood Flow Metab. 20, 175-182.
-
(2000)
J. Cereb. Blood Flow Metab.
, vol.20
, pp. 175-182
-
-
Bartha, K.1
Domotor, E.2
Lanza, F.3
Adam-Vizi, V.4
Machovich, R.5
-
4
-
-
4243405831
-
Thrombin activates mitogen activated protein kinases through protease activated receptor-1
-
(Washington, DC, USA: Society for Neuroscience). Online: Abstract Viewer/Itinerary Planner, Program No. 300.307
-
Chen, X., Hua, Y., Keep, R. F., Jiang, Y, Wu, J., Hoff, J. T. and Xi, G. (2002). Thrombin activates mitogen activated protein kinases through protease activated receptor-1 (Washington, DC, USA: Society for Neuroscience). Online: Abstract Viewer/Itinerary Planner, Program No. 300.307.
-
(2002)
-
-
Chen, X.1
Hua, Y.2
Keep, R.F.3
Jiang, Y.4
Wu, J.5
Hoff, J.T.6
Xi, G.7
-
5
-
-
0030612752
-
The G12 coupled thrombin receptor stimulates mitogenesis through the Shc SH2 domain
-
Collins, L. R., Ricketts, W. A., Olefsky, J. M. and Brown, J. H. (1997). The G12 coupled thrombin receptor stimulates mitogenesis through the Shc SH2 domain. Oncogene 15, 595-600.
-
(1997)
Oncogene
, vol.15
, pp. 595-600
-
-
Collins, L.R.1
Ricketts, W.A.2
Olefsky, J.M.3
Brown, J.H.4
-
6
-
-
0034648757
-
Thrombin signalling and protease-activated receptors
-
Coughlin, S. (2000). Thrombin signalling and protease-activated receptors. Nature 407, 258-264.
-
(2000)
Nature
, vol.407
, pp. 258-264
-
-
Coughlin, S.1
-
7
-
-
0028031081
-
Protease-activated receptors start a family
-
Coughlin, S. R. (1994). Protease-activated receptors start a family. Proc. Natl. Acad. Sci. USA 91, 9200-9202.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9200-9202
-
-
Coughlin, S.R.1
-
8
-
-
0028027214
-
Thrombin receptor activation induces secretion and nonamyloidogenic processing of amyloid β-protein precursor
-
Davis-Salinas, J., Saporito-Irwin, S. M., Donovan, F. M., Cunningham, D. D. and Van Nostrand, W. E. (1994). Thrombin receptor activation induces secretion and nonamyloidogenic processing of amyloid β-protein precursor. J. Biol. Chem. 269, 22623-22627.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 22623-22627
-
-
Davis-Salinas, J.1
Saporito-Irwin, S.M.2
Donovan, F.M.3
Cunningham, D.D.4
Van Nostrand, W.E.5
-
9
-
-
0029896145
-
Transduction mechanisms involved in thrombin receptor-induced nerve growth factor secretion and cell division in primary cultures of astrocytes
-
Debeir, T., Gueugnon, J., Vige, X. and Benavides, J. (1996). Transduction mechanisms involved in thrombin receptor-induced nerve growth factor secretion and cell division in primary cultures of astrocytes. J. Neurochem. 66, 2320-2328.
-
(1996)
J. Neurochem.
, vol.66
, pp. 2320-2328
-
-
Debeir, T.1
Gueugnon, J.2
Vige, X.3
Benavides, J.4
-
10
-
-
0025857712
-
Prothrombin mRNA is expressed by cells of the nervous system
-
Dihanich, M., Kaser, M., Reinhard, E., Cunningham, D. and Monard, D. (1991). Prothrombin mRNA is expressed by cells of the nervous system. Neuron 6, 575-581.
-
(1991)
Neuron
, vol.6
, pp. 575-581
-
-
Dihanich, M.1
Kaser, M.2
Reinhard, E.3
Cunningham, D.4
Monard, D.5
-
11
-
-
0032557654
-
Signaling pathways involved in thrombin-induced cell protection
-
Donovan, F. M. and Cunningham, D. D. (1998). Signaling pathways involved in thrombin-induced cell protection. J. Biol. Chem. 273, 12746-12752.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12746-12752
-
-
Donovan, F.M.1
Cunningham, D.D.2
-
12
-
-
16944366731
-
Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities
-
Donovan, F. M., Pike, C. J., Cotman, C. W. and Cunningham, D. D. (1997). Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities. J. Neurosci. 17, 5316-5326.
-
(1997)
J. Neurosci.
, vol.17
, pp. 5316-5326
-
-
Donovan, F.M.1
Pike, C.J.2
Cotman, C.W.3
Cunningham, D.D.4
-
13
-
-
0027470910
-
Thrombin is a regulator of astrocytic endothelin-1
-
Ehrenreich, H., Costa, T, Clouse, K. A., Pluta, R. M., Ogino, Y., Coligan, J. E. and Burd, P. R. (1993). Thrombin is a regulator of astrocytic endothelin-1. Brain. Res. 600, 201-207.
-
(1993)
Brain Res.
, vol.600
, pp. 201-207
-
-
Ehrenreich, H.1
Costa, T.2
Clouse, K.A.3
Pluta, R.M.4
Ogino, Y.5
Coligan, J.E.6
Burd, P.R.7
-
14
-
-
0035154139
-
Thrombin attenuation is neuroprotective in the injured rat optic nerve
-
Friedmann, I., Yoles, E. and Schwartz, M. (2001). Thrombin attenuation is neuroprotective in the injured rat optic nerve. J. Neurochem. 76, 641-649.
-
(2001)
J. Neurochem.
, vol.76
, pp. 641-649
-
-
Friedmann, I.1
Yoles, E.2
Schwartz, M.3
-
15
-
-
0030929149
-
Identification of a novel, putative Rho-specific GDP/GTP exchange factor and a RhoA-binding protein: Control of neuronal morphology
-
Gebbink, M. F., Kranenburg, O., Poland, M., van Horck, F. P., Houssa, B. and Moolenaar, W. H. (1997). Identification of a novel, putative Rho-specific GDP/GTP exchange factor and a RhoA-binding protein: control of neuronal morphology. J. Cell. Biol. 137, 1603-1613.
-
(1997)
J. Cell. Biol.
, vol.137
, pp. 1603-1613
-
-
Gebbink, M.F.1
Kranenburg, O.2
Poland, M.3
van Horck, F.P.4
Houssa, B.5
Moolenaar, W.H.6
-
16
-
-
0034660448
-
Potentiation of NMDA receptor function by the serine protease thrombin
-
Gingrich, M. B., Junge, C. E., Lyuboslavsky, P. and Traynelis, S. F. (2000). Potentiation of NMDA receptor function by the serine protease thrombin. J. Neurosci. 20, 4582-4595.
-
(2000)
J. Neurosci.
, vol.20
, pp. 4582-4595
-
-
Gingrich, M.B.1
Junge, C.E.2
Lyuboslavsky, P.3
Traynelis, S.F.4
-
17
-
-
0034284153
-
Serine proteases and brain damage - Is there a link?
-
Gingrich, M. B. and Traynelis, S. F. (2000). Serine proteases and brain damage - is there a link? Trends Neurosci. 23, 399-407.
-
(2000)
Trends Neurosci.
, vol.23
, pp. 399-407
-
-
Gingrich, M.B.1
Traynelis, S.F.2
-
18
-
-
0028873060
-
Thrombin receptor activation stimulates astrocyte proliferation and reversal of stellation by distinct pathways: Involvement of tyrosine phosphorylation
-
Grabham, P. and Cunningham, D. D. (1995). Thrombin receptor activation stimulates astrocyte proliferation and reversal of stellation by distinct pathways: involvement of tyrosine phosphorylation. J. Neurochem. 64, 583-591.
-
(1995)
J. Neurochem.
, vol.64
, pp. 583-591
-
-
Grabham, P.1
Cunningham, D.D.2
-
19
-
-
0034729916
-
Rho GTPases: Molecular switches that control the organization and dynamics of the actin cytoskeleton
-
Hall, A., and Nobes, C. D. (2000). Rho GTPases: molecular switches that control the organization and dynamics of the actin cytoskeleton. Philos. Trans. R. Soc. Lond. B Biol. Sci. 355, 965-970.
-
(2000)
Philos. Trans. R. Soc. Lond. B. Biol. Sci.
, vol.355
, pp. 965-970
-
-
Hall, A.1
Nobes, C.D.2
-
21
-
-
0036262319
-
Proteinase-activated receptors
-
International Union of Pharmacology. XXVIII
-
Hollenberg, M. D. and Compton, S. J. (2002). International Union of Pharmacology. XXVIII. Proteinase-activated receptors. Pharmacol. Rev. 54, 203-217.
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 203-217
-
-
Hollenberg, M.D.1
Compton, S.J.2
-
22
-
-
0030979972
-
Protease-activated receptor 3 is a second thrombin receptor in humans
-
Ishihara, H., Connolly, A. J., Zeng, D., Kahn, M. L., Zheng, Y. W., Timmons, C., Tram, T and Coughlin, S. R. (1997). Protease-activated receptor 3 is a second thrombin receptor in humans. Nature 386, 502-506.
-
(1997)
Nature
, vol.386
, pp. 502-506
-
-
Ishihara, H.1
Connolly, A.J.2
Zeng, D.3
Kahn, M.L.4
Zheng, Y.W.5
Timmons, C.6
Tram, T.7
Coughlin, S.R.8
-
23
-
-
0026748742
-
Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers
-
Jalink, K. and Moolenaar, W. H. (1992). Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers. J. Cell. Biol. 118, 411-419.
-
(1992)
J. Cell. Biol.
, vol.118
, pp. 411-419
-
-
Jalink, K.1
Moolenaar, W.H.2
-
24
-
-
0028021308
-
Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho
-
Jalink, K., van-Corven, E. J., Hengeveld, T, Morii, N., Narumiya, S. and Moolenaar, W. H. (1994). Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J. Cell. Biol. 126, 801-810.
-
(1994)
J. Cell. Biol.
, vol.126
, pp. 801-810
-
-
Jalink, K.1
van-Corven, E.J.2
Hengeveld, T.3
Morii, N.4
Narumiya, S.5
Moolenaar, W.H.6
-
25
-
-
0036211918
-
Thrombin-receptor activation and thrombin-induced brain tolerance
-
Jiang, Y., Wu, J., Hua, Y, Keep, R. F., Xiang, J., Hoff, J. T. and Xi, G. (2002). Thrombin-receptor activation and thrombin-induced brain tolerance. J. Cereb. Blood Flow Metab. 22, 404-410.
-
(2002)
J. Cereb. Blood Flow Metab.
, vol.22
, pp. 404-410
-
-
Jiang, Y.1
Wu, J.2
Hua, Y.3
Keep, R.F.4
Xiang, J.5
Hoff, J.T.6
Xi, G.7
-
26
-
-
0032514474
-
A dual thrombin receptor system for platelet activation
-
Kahn, M. L., Zheng, Y. W., Huang, W., Bigornia, V., Zeng, D., Moff, S., Farese, R. V. J., Tam, C. and Coughlin, S. R. (1998). A dual thrombin receptor system for platelet activation. Nature 394, 690-694.
-
(1998)
Nature
, vol.394
, pp. 690-694
-
-
Kahn, M.L.1
Zheng, Y.W.2
Huang, W.3
Bigornia, V.4
Zeng, D.5
Moff, S.6
Farese, R.V.J.7
Tam, C.8
Coughlin, S.R.9
-
27
-
-
0033559805
-
Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin
-
Kahn, M. L., Nakanishi-Matsui, M., Shapiro, M. J., Ishihara, H. and Coughlin, S. R. (1999). Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J. Clin. Invest. 103, 879-887.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 879-887
-
-
Kahn, M.L.1
Nakanishi-Matsui, M.2
Shapiro, M.J.3
Ishihara, H.4
Coughlin, S.R.5
-
28
-
-
0033968332
-
i mobilization in human astrocytoma cells
-
i mobilization in human astrocytoma cells. J. Cancer Res. Clin. Oncol. 126, 91-94.
-
(2000)
J. Cancer Res. Clin. Oncol.
, vol.126
, pp. 91-94
-
-
Kaufmann, R.1
Patt, S.2
Zieger, M.3
Kraft, R.4
Tausch, S.5
Henklein, P.6
Nowak, G.7
-
29
-
-
0033773513
-
Intrathecal administration of thrombin inhibitor ameliorates cerebral vasospasm. Use of a drug delivery system releasing hirudin
-
Kudo, A., Suzuki, M., Kubo, Y., Watanabe, M., Yoshida, K., Doi, M., Kuroda, K. and Ogawa, A. (2000). Intrathecal administration of thrombin inhibitor ameliorates cerebral vasospasm. Use of a drug delivery system releasing hirudin. Cerebrovasc. Dis. 10, 424-430.
-
(2000)
Cerebrovasc. Dis.
, vol.10
, pp. 424-430
-
-
Kudo, A.1
Suzuki, M.2
Kubo, Y.3
Watanabe, M.4
Yoshida, K.5
Doi, M.6
Kuroda, K.7
Ogawa, A.8
-
30
-
-
0029943079
-
Agonist recognition by proteinase-activated receptor 2 and thrombin receptor. Importance of extracellular loop interactions for receptor function
-
Lerner, D. J., Chen, M., Tram, T. and Coughlin, S. R. (1996). Agonist recognition by proteinase-activated receptor 2 and thrombin receptor. Importance of extracellular loop interactions for receptor function. J. Biol. Chem. 271, 13943-13947.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13943-13947
-
-
Lerner, D.J.1
Chen, M.2
Tram, T.3
Coughlin, S.R.4
-
31
-
-
0035019636
-
Proteinase-activated receptors
-
Macfarlane, S. R., Seatter, M. J., Kanke, T., Hunter, G. D. and Plevin, R. (2001). Proteinase-activated receptors. Pharmacol. Rev. 53, 245-282.
-
(2001)
Pharmacol. Rev.
, vol.53
, pp. 245-282
-
-
Macfarlane, S.R.1
Seatter, M.J.2
Kanke, T.3
Hunter, G.D.4
Plevin, R.5
-
32
-
-
0034710947
-
Creatine kinase, an ATP-generating enzyme, is required for thrombin receptor signaling to the cytoskeleton
-
Mahajan, V. B., Pai, K. S., Lau, A. and Cunningham, D. D. (2000). Creatine kinase, an ATP-generating enzyme, is required for thrombin receptor signaling to the cytoskeleton. Proc. Natl. Acad. Sci. USA 97, 12062-12067.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12062-12067
-
-
Mahajan, V.B.1
Pai, K.S.2
Lau, A.3
Cunningham, D.D.4
-
34
-
-
0032562675
-
Requirement for Rho-mediated myosin light chain phosphorylation in thrombin-stimulated cell rounding and its dissociation from mitogenesis
-
Majumdar, M., Seasholtz, T. M., Goldstein, D., de Lanerolle, P. and Brown, J. H. (1998). Requirement for Rho-mediated myosin light chain phosphorylation in thrombin-stimulated cell rounding and its dissociation from mitogenesis. J. Biol. Chem. 273, 10099-10106.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10099-10106
-
-
Majumdar, M.1
Seasholtz, T.M.2
Goldstein, D.3
de Lanerolle, P.4
Brown, J.H.5
-
35
-
-
0034625743
-
The effects of thrombin preconditioning on focal cerebral ischemia in rats
-
Masada, T., Xi, G., Hua, Y. and Keep, R. F. (2000). The effects of thrombin preconditioning on focal cerebral ischemia in rats. Brain Res. 867, 173-179.
-
(2000)
Brain Res.
, vol.867
, pp. 173-179
-
-
Masada, T.1
Xi, G.2
Hua, Y.3
Keep, R.F.4
-
36
-
-
0034756207
-
Thrombin and PAR-1 activating peptide increase iNOS expression in cytokine-stimulated C6 glioma cells
-
Meli, R., Raso, G. M., Cicala, C., Esposito, E., Fiorino, F. and Cirino, G. (2001). Thrombin and PAR-1 activating peptide increase iNOS expression in cytokine-stimulated C6 glioma cells. J. Neurochem. 79, 556-563.
-
(2001)
J. Neurochem.
, vol.79
, pp. 556-563
-
-
Meli, R.1
Raso, G.M.2
Cicala, C.3
Esposito, E.4
Fiorino, F.5
Cirino, G.6
-
37
-
-
0029790022
-
Exposure of astrocytes to thrombin reduces levels of the metabotropic glutamate receptor mGluR5
-
Miller, S., Sehati, N., Romano, C. and Cotman, C. W. (1996). Exposure of astrocytes to thrombin reduces levels of the metabotropic glutamate receptor mGluR5. J. Neurochem. 67, 1435-1447.
-
(1996)
J. Neurochem.
, vol.67
, pp. 1435-1447
-
-
Miller, S.1
Sehati, N.2
Romano, C.3
Cotman, C.W.4
-
38
-
-
0033822556
-
Thrombin-induced activation of cultured rodent microglia
-
Möller, T, Hanisch, U. K. and Ransom, B. R. (2000). Thrombin-induced activation of cultured rodent microglia. J. Neurochem. 75, 1539-1547.
-
(2000)
J. Neurochem.
, vol.75
, pp. 1539-1547
-
-
Möller, T.1
Hanisch, U.K.2
Ransom, B.R.3
-
39
-
-
0027510492
-
Enhancement of the synthesis and secretion of nerve growth factor in primary cultures of glial cells by proteases: A possible involvement of thrombin
-
Neveu, I., Jehan, F., Jandrot Perrus, M., Wion, D. and Brachet, P. (1993). Enhancement of the synthesis and secretion of nerve growth factor in primary cultures of glial cells by proteases: a possible involvement of thrombin. J. Neurochem. 60, 858-867.
-
(1993)
J. Neurochem.
, vol.60
, pp. 858-867
-
-
Neveu, I.1
Jehan, F.2
Jandrot Perrus, M.3
Wion, D.4
Brachet, P.5
-
40
-
-
0031844717
-
Changes in the expression of protease-activated receptor 1 and protease nexin-1 mRNA during rat nervous system development and after nerve lesion
-
Niclou, S. P., Suidan, H. S., Pavlik, A., Vejsada, R. and Monard, D. (1998). Changes in the expression of protease-activated receptor 1 and protease nexin-1 mRNA during rat nervous system development and after nerve lesion. Eur. J. Neurosci. 10, 1590-1607.
-
(1998)
Eur. J. Neurosci.
, vol.10
, pp. 1590-1607
-
-
Niclou, S.P.1
Suidan, H.S.2
Pavlik, A.3
Vejsada, R.4
Monard, D.5
-
41
-
-
0034608013
-
Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1
-
O'Brien, P. J., Prevost, N., Molino, M., Hollinger, M. K., Woolkalis, M. J., Woulfe, D. S. and Brass, L. F. (2000). Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1. J. Biol. Chem. 275, 13502-13509.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13502-13509
-
-
O'Brien, P.J.1
Prevost, N.2
Molino, M.3
Hollinger, M.K.4
Woolkalis, M.J.5
Woulfe, D.S.6
Brass, L.F.7
-
42
-
-
0035368457
-
Thrombin inhibition attenuates neurodegeneration and cerebral edema formation following transient forebrain ischemia
-
Ohyama, H., Hosomi, N., Takahashi, T, Mizushige, K. and Kohno, M. (2001). Thrombin inhibition attenuates neurodegeneration and cerebral edema formation following transient forebrain ischemia. Brain. Res. 902, 264-271.
-
(2001)
Brain Res.
, vol.902
, pp. 264-271
-
-
Ohyama, H.1
Hosomi, N.2
Takahashi, T.3
Mizushige, K.4
Kohno, M.5
-
43
-
-
0036323761
-
Geldanamycin specifically modulates thrombin-mediated morphological changes in mouse neuroblasts
-
Pai, K. S. and Cunningham, D. D. (2002). Geldanamycin specifically modulates thrombin-mediated morphological changes in mouse neuroblasts. J. Neurochem. 80, 715-718.
-
(2002)
J. Neurochem.
, vol.80
, pp. 715-718
-
-
Pai, K.S.1
Cunningham, D.D.2
-
44
-
-
0035980107
-
Thrombin receptor signaling to cytoskeleton requires Hsp90
-
Pai, K. S., Mahajan, V. B., Lau, A. and Cunningham, D. D. (2001). Thrombin receptor signaling to cytoskeleton requires Hsp90. J. Biol. Chem. 276, 32642-32647.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 32642-32647
-
-
Pai, K.S.1
Mahajan, V.B.2
Lau, A.3
Cunningham, D.D.4
-
45
-
-
0035952645
-
New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades
-
Pierce, K. L., Luttrell, L. M. and Lefkowitz, R. J. (2001). New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades. Oncogene 20, 1532-1539.
-
(2001)
Oncogene
, vol.20
, pp. 1532-1539
-
-
Pierce, K.L.1
Luttrell, L.M.2
Lefkowitz, R.J.3
-
46
-
-
0025784847
-
2+ mobilization
-
2+ mobilization. FEBS Lett. 288, 123-128.
-
(1991)
FEBS Lett.
, vol.288
, pp. 123-128
-
-
Rasmussen, U.B.1
Vouret-Craviari, V.2
Jallat, S.3
Schlesinger, Y.4
Pages, G.5
Pavirani, A.6
Lecocq, J.P.7
Pouyssegur, J.8
Van Obberghen-Schilling, E.9
-
47
-
-
0035876863
-
Mechanisms of cell death in primary cortical neurons and PC12 cells
-
Reimann-Philipp, U., Ovase, R., Weigel, P. H. and Grammas, P. (2001). Mechanisms of cell death in primary cortical neurons and PC12 cells. J. Neurosci. Res. 64, 654-660.
-
(2001)
J. Neurosci. Res.
, vol.64
, pp. 654-660
-
-
Reimann-Philipp, U.1
Ovase, R.2
Weigel, P.H.3
Grammas, P.4
-
48
-
-
0027976526
-
Glia-derived nexin/protease nexin-1 is expressed by a subset of neurons in the rat brain
-
Reinhard, E., Suidan, H. S., Pavlik, A. and Monard, D. (1994). Glia-derived nexin/protease nexin-1 is expressed by a subset of neurons in the rat brain. J. Neurosci. Res. 37, 256-270.
-
(1994)
J. Neurosci. Res.
, vol.37
, pp. 256-270
-
-
Reinhard, E.1
Suidan, H.S.2
Pavlik, A.3
Monard, D.4
-
49
-
-
0030968521
-
Specific inhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G, and proteinase 3: Evidence for distinct cleavage sites within the amino terminal domain of the thrombin receptor
-
Renesto, P., Si-Tahar, M., Moniatte, M., Balloy, V., Van Dorsselaer, A., Pidard, D. and Chignard, M. (1997). Specific inhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G, and proteinase 3: evidence for distinct cleavage sites within the amino terminal domain of the thrombin receptor. Blood 89, 1944 -1953.
-
(1997)
Blood
, vol.89
, pp. 1944-1953
-
-
Renesto, P.1
Si-Tahar, M.2
Moniatte, M.3
Balloy, V.4
Van Dorsselaer, A.5
Pidard, D.6
Chignard, M.7
-
50
-
-
0037144497
-
Signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain
-
Russo, C., Dolcini, V., Salis, S., Venezia, V, Zambrano, N., Russo, T. and Schettini, G. (2002). Signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain. J. Biol. Chem. 277, 35282-35288.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 35282-35288
-
-
Russo, C.1
Dolcini, V.2
Salis, S.3
Venezia, V.4
Zambrano, N.5
Russo, T.6
Schettini, G.7
-
51
-
-
0025329390
-
The structure of a complex of recombinant hirudin and human α-thrombin
-
Rydel, T. J., Ravichandran, K. G., Tulinsky, A., Bode, W., Huber, R., Roitsch, C. and Fenton, J. W. (1990). The structure of a complex of recombinant hirudin and human α-thrombin. Science 249, 277-280.
-
(1990)
Science
, vol.249
, pp. 277-280
-
-
Rydel, T.J.1
Ravichandran, K.G.2
Tulinsky, A.3
Bode, W.4
Huber, R.5
Roitsch, C.6
Fenton, J.W.7
-
52
-
-
0034730753
-
Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-κB
-
Ryu, J., Pyo, H., Jou, I. and Joe, E. (2000). Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-κB. J. Biol. Chem. 275, 29955-29959.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 29955-29959
-
-
Ryu, J.1
Pyo, H.2
Jou, I.3
Joe, E.4
-
53
-
-
0032510949
-
The human proteinase-activated receptor-3 (PAR-3) gene. Identification within a PAR gene cluster and characterization in vascular endothelial cells and platelets
-
Schmidt, V. A., Nierman, W. C., Maglott, D. R., Cupit, L. D., Moskowitz, K. A., Wainer, J. A. and Bahou, W. F. (1998). The human proteinase-activated receptor-3 (PAR-3) gene. Identification within a PAR gene cluster and characterization in vascular endothelial cells and platelets. J. Biol. Chem. 273, 15061 -15068.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15061-15068
-
-
Schmidt, V.A.1
Nierman, W.C.2
Maglott, D.R.3
Cupit, L.D.4
Moskowitz, K.A.5
Wainer, J.A.6
Bahou, W.F.7
-
56
-
-
0031813736
-
Thrombin is an extracellular signal that activates intracellular death protease pathways inducing apoptosis in model motor neurons
-
Smirnova, I. V., Zhang, S. X., Citron, B. A., Arnold, P. M. and Festoff, B. W. (1998). Thrombin is an extracellular signal that activates intracellular death protease pathways inducing apoptosis in model motor neurons. J. Neurobiol. 36, 64-80.
-
(1998)
J. Neurobiol.
, vol.36
, pp. 64-80
-
-
Smirnova, I.V.1
Zhang, S.X.2
Citron, B.A.3
Arnold, P.M.4
Festoff, B.W.5
-
57
-
-
0034053127
-
The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations
-
Striggow, F, Riek, M., Breder, J., Henrich Noack, P., Reymann, K. G. and Reiser, G. (2000). The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations. Proc. Natl. Acad. Sci. USA 97, 2264-2269.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2264-2269
-
-
Striggow, F.1
Riek, M.2
Breder, J.3
Henrich Noack, P.4
Reymann, K.G.5
Reiser, G.6
-
58
-
-
0036285822
-
Four different types of protease-activated receptors are widely expressed in the brain and are up-regulated in hippocampus by severe ischemia
-
Striggow, F., Riek-Burchardt, M., Kiesel, A., Schmidt, W., Henrich-Noack, P., Breder, J., Krug, M., Reymann, K. G. and Reiser, G. (2001). Four different types of protease-activated receptors are widely expressed in the brain and are up-regulated in hippocampus by severe ischemia. Eur. J. Neurosci. 14, 595-608.
-
(2001)
Eur. J. Neurosci.
, vol.14
, pp. 595-608
-
-
Striggow, F.1
Riek-Burchardt, M.2
Kiesel, A.3
Schmidt, W.4
Henrich-Noack, P.5
Breder, J.6
Krug, M.7
Reymann, K.G.8
Reiser, G.9
-
59
-
-
0031260271
-
Astrocyte spreading in response to thrombin and lysophosphatidic acid is dependent on the Rho GTPase
-
Suidan, H. S., Nobes, C. D., Hall, A. and Monard, D. (1997). Astrocyte spreading in response to thrombin and lysophosphatidic acid is dependent on the Rho GTPase. Glia 21, 244-252.
-
(1997)
Glia
, vol.21
, pp. 244-252
-
-
Suidan, H.S.1
Nobes, C.D.2
Hall, A.3
Monard, D.4
-
60
-
-
0036326804
-
Participation of protease-activated receptor-1 in thrombin-induced microglial activation
-
Suo, Z., Wu, M., Ameenuddin, S., Anderson, H. E., Zoloty, J. E., Citron, B. A., Andrade-Gordon, P. and Festoff, B. W. (2002a). Participation of protease-activated receptor-1 in thrombin-induced microglial activation. J. Neurochem. 80, 655-666.
-
(2002)
J. Neurochem.
, vol.80
, pp. 655-666
-
-
Suo, Z.1
Wu, M.2
Ameenuddin, S.3
Anderson, H.E.4
Zoloty, J.E.5
Citron, B.A.6
Andrade-Gordon, P.7
Festoff, B.W.8
-
61
-
-
4244169474
-
Persistent protease-activated receptor 4 signaling mediates thrombin-induced microglial activation
-
(Washington, DC, USA: Society for Neuroscience). Online: Abstract Viewer/Itinerary Planner, Program no. 190.191
-
Suo, Z., Wu, M., Citron, B. A. and Festoff, B. W. (2002b). Persistent protease-activated receptor 4 signaling mediates thrombin-induced microglial activation (Washington, DC, USA: Society for Neuroscience). Online: Abstract Viewer/Itinerary Planner, Program no. 190.191.
-
(2002)
-
-
Suo, Z.1
Wu, M.2
Citron, B.A.3
Festoff, B.W.4
-
62
-
-
17344365478
-
Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activation
-
Turgeon, V. L., Lloyd, E. D., Wang, S., Festoff, B. W. and Houenou, L. J. (1998). Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activation. J. Neurosci. 18, 6882-6891.
-
(1998)
J. Neurosci.
, vol.18
, pp. 6882-6891
-
-
Turgeon, V.L.1
Lloyd, E.D.2
Wang, S.3
Festoff, B.W.4
Houenou, L.J.5
-
63
-
-
0029029463
-
Regulation of neurite outgrowth from differentiated human neuroepithelial cells: A comparison of the activities of prothrombin and thrombin
-
Turnell, A. S., Brant, D. P., Brown, G. R., Finney, M., Gallimore, P. H., Kirk, C. J., Pagliuca, T. R., Campbell, C. J., Michell, R. H. and Grand, R. J. (1995). Regulation of neurite outgrowth from differentiated human neuroepithelial cells: a comparison of the activities of prothrombin and thrombin. Biochem. J. 308, 965-973.
-
(1995)
Biochem. J.
, vol.308
, pp. 965-973
-
-
Turnell, A.S.1
Brant, D.P.2
Brown, G.R.3
Finney, M.4
Gallimore, P.H.5
Kirk, C.J.6
Pagliuca, T.R.7
Campbell, C.J.8
Michell, R.H.9
Grand, R.J.10
-
64
-
-
0034473058
-
2+ signalling evoked by proteinase-activated receptor-1 (PAR-1) in rat astrocytes
-
2+ signalling evoked by proteinase-activated receptor-1 (PAR-1) in rat astrocytes. Adv. Exp. Med. Biol. 477, 323-329.
-
(2000)
Adv. Exp. Med. Biol.
, vol.477
, pp. 323-329
-
-
Ubl, J.J.1
Reiser, G.2
-
66
-
-
0029012029
-
Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults
-
Vaughan, P. J., Pike, C. J., Cotman, C. W. and Cunningham, D. D. (1995). Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults. J. Neurosci. 15, 5389-5401.
-
(1995)
J. Neurosci.
, vol.15
, pp. 5389-5401
-
-
Vaughan, P.J.1
Pike, C.J.2
Cotman, C.W.3
Cunningham, D.D.4
-
67
-
-
0028566867
-
Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease
-
Vaughan, P. J., Su, J., Cotman, C. W. and Cunningham, D. D. (1994). Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease. Brain. Res. 668, 160-170.
-
(1994)
Brain Res.
, vol.668
, pp. 160-170
-
-
Vaughan, P.J.1
Su, J.2
Cotman, C.W.3
Cunningham, D.D.4
-
68
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
-
Vu, T. K., Hung, D. T., Wheaton, V. I. and Coughlin, S. R. (1991). Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64, 1057-1068.
-
(1991)
Cell
, vol.64
, pp. 1057-1068
-
-
Vu, T.K.1
Hung, D.T.2
Wheaton, V.I.3
Coughlin, S.R.4
-
69
-
-
0037332454
-
2+-sensitive tyrosine kinase Pyk2 and Src in thrombin signaling in rat astrocytes
-
in press
-
2+-sensitive tyrosine kinase Pyk2 and Src in thrombin signaling in rat astrocytes. J. Neurochem., in press.
-
(2003)
J. Neurochem.
-
-
Wang, H.1
Reiser, G.2
-
70
-
-
0036006726
-
The four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling
-
Wang, H., Ubl, J. J. and Reiser, G. (2002a). The four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling. Glia 37, 53-63.
-
(2002)
Glia
, vol.37
, pp. 53-63
-
-
Wang, H.1
Ubl, J.J.2
Reiser, G.3
-
71
-
-
0036838021
-
Thrombin (PAR-1)-induced proliferation in astrocytes via MAP kinase involves multiple signaling pathways
-
Wang, H., Ubl, J. J., Stricker, R. and Reiser, G. (2002b). Thrombin (PAR-1)-induced proliferation in astrocytes via MAP kinase involves multiple signaling pathways. Am. J. Physiol. Cell Physiol. 283, C1351-C1364.
-
(2002)
Am. J. Physiol. Cell Physiol.
, vol.283
-
-
Wang, H.1
Ubl, J.J.2
Stricker, R.3
Reiser, G.4
-
72
-
-
0033000918
-
Attenuation of thrombin-induced brain edema by cerebral thrombin preconditioning
-
Xi, G., Keep, R. F., Hua, Y., Xiang, J. and Hoff, J. T. (1999). Attenuation of thrombin-induced brain edema by cerebral thrombin preconditioning. Stroke 30, 1247-1255.
-
(1999)
Stroke
, vol.30
, pp. 1247-1255
-
-
Xi, G.1
Keep, R.F.2
Hua, Y.3
Xiang, J.4
Hoff, J.T.5
-
73
-
-
0034570591
-
Thrombin preconditioning, heat shock proteins and thrombin-induced brain edema
-
Xi, G., Keep, R. F., Hua, Y. and Hoff, J. T. (2000). Thrombin preconditioning, heat shock proteins and thrombin-induced brain edema. Acta Neurochir. 76 (Suppl.), 511-515.
-
(2000)
Acta Neurochir.
, vol.76
, Issue.SUPPL.
, pp. 511-515
-
-
Xi, G.1
Keep, R.F.2
Hua, Y.3
Hoff, J.T.4
-
74
-
-
0035937433
-
Activation of p44/42 mitogen activated protein kinases in thrombin-induced brain tolerance
-
Xi, G., Hua, Y., Keep, R. F., Duong, H. K. and Hoff, J. T. (2001). Activation of p44/42 mitogen activated protein kinases in thrombin-induced brain tolerance. Brain. Res. 895, 153-159.
-
(2001)
Brain Res.
, vol.895
, pp. 153-159
-
-
Xi, G.1
Hua, Y.2
Keep, R.F.3
Duong, H.K.4
Hoff, J.T.5
-
75
-
-
0037265689
-
The role of thrombin and thrombin receptors in ischemic, homorrhagic and traumatic brain injury: Deleterious or protective?
-
Xi, G., Reiser, G. and Keep, R. F. (2003). The role of thrombin and thrombin receptors in ischemic, homorrhagic and traumatic brain injury: deleterious or protective? J. Neurochem. 84, 3-9.
-
(2003)
J. Neurochem.
, vol.84
, pp. 3-9
-
-
Xi, G.1
Reiser, G.2
Keep, R.F.3
-
76
-
-
0032499696
-
Cloning and characterization of human protease-activated receptor 4
-
Xu, W. F., Andersen, H., Whitmore, T. E., Presnell, S. R., Yee, D. P., Ching, A., Gilbert, T., Davie, E. W. and Foster, D. C. (1998). Cloning and characterization of human protease-activated receptor 4. Proc. Natl. Acad. Sci. USA 95, 6642-6646.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6642-6646
-
-
Xu, W.F.1
Andersen, H.2
Whitmore, T.E.3
Presnell, S.R.4
Yee, D.P.5
Ching, A.6
Gilbert, T.7
Davie, E.W.8
Foster, D.C.9
-
77
-
-
0034827647
-
Acute tissue damage after injections of thrombin and plasmin into rat striatum
-
Xue, M. and Del Bigio, M. R. (2001). Acute tissue damage after injections of thrombin and plasmin into rat striatum. Stroke 32, 2164-2169.
-
(2001)
Stroke
, vol.32
, pp. 2164-2169
-
-
Xue, M.1
Del Bigio, M.R.2
-
78
-
-
0035939668
-
U. Hsp9O: A specialized but essential protein-folding tool
-
Young, J. C., Moarefi, I. and Hartl, F. U. (2001). Hsp9O: a specialized but essential protein-folding tool. J. Cell. Biol. 154, 267-273.
-
(2001)
J. Cell. Biol.
, vol.154
, pp. 267-273
-
-
Young, J.C.1
Moarefi, I.2
Hartl, F.3
-
79
-
-
0034810131
-
A novel PAR-1-type thrombin receptor signaling pathway: Cyclic AMP-independent activation of PKA in SNB-19 glioblastoma cells
-
Zieger, M., Tausch, S., Henklein, P., Nowak, G. and Kaufmann, R. (2001). A novel PAR-1-type thrombin receptor signaling pathway: cyclic AMP-independent activation of PKA in SNB-19 glioblastoma cells. Biochem. Biophys. Res. Commun. 282, 952-957.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.282
, pp. 952-957
-
-
Zieger, M.1
Tausch, S.2
Henklein, P.3
Nowak, G.4
Kaufmann, R.5
|