-
1
-
-
0034818446
-
Post-translational modifications and activation of p53 by genotoxic stresses
-
Appella E. and Anderson C.W. 2001. Post-translational modifications and activation of p53 by genotoxic stresses. Eur. J. Biochem. 268: 2764.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 2764
-
-
Appella, E.1
Anderson, C.W.2
-
2
-
-
0034654623
-
PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family
-
Attardi L.D., Reczek E.E., Cosmas C., Demicco E.G., McCurrach M.E., Lowe S.W., and Jacks T. 2000. PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family. Genes Dev. 14: 704.
-
(2000)
Genes Dev.
, vol.14
, pp. 704
-
-
Attardi, L.D.1
Reczek, E.E.2
Cosmas, C.3
Demicco, E.G.4
McCurrach, M.E.5
Lowe, S.W.6
Jacks, T.7
-
3
-
-
0028339379
-
Is p53 polymorphism maintained by natural selection?
-
Beckman G., Birgander R., Sjalander A., Saha N, Holmberg P.A., Kivela A., and Beckman L. 1994. Is p53 polymorphism maintained by natural selection? Hum. Hered. 44: 266.
-
(1994)
Hum. Hered.
, vol.44
, pp. 266
-
-
Beckman, G.1
Birgander, R.2
Sjalander, A.3
Saha, N.4
Holmberg, P.A.5
Kivela, A.6
Beckman, L.7
-
4
-
-
15244344356
-
A portrait of AKT kinases: Human cancer and animal models depict a family with strong individualities
-
Bellacosa A., Testa J.R., Moore R., and Larue L. 2004. A portrait of AKT kinases: Human cancer and animal models depict a family with strong individualities. Cancer Biol. Ther. 3: 268.
-
(2004)
Cancer Biol. Ther.
, vol.3
, pp. 268
-
-
Bellacosa, A.1
Testa, J.R.2
Moore, R.3
Larue, L.4
-
5
-
-
0035057382
-
p53 functional assays: Detecting p53 mutations in both the germline and in sporadic tumours
-
Camplejohn R.S. and Rutherford J. 2001. p53 functional assays: Detecting p53 mutations in both the germline and in sporadic tumours. Cell Prolif. 34: 1.
-
(2001)
Cell Prolif.
, vol.34
, pp. 1
-
-
Camplejohn, R.S.1
Rutherford, J.2
-
6
-
-
0034052306
-
The value of rapid functional assays of germline p53 status in LFS and LFL families
-
Camplejohn R.S., Sodha N., Gilchrist R., Lomax M.E., Duddy P.M., Miner C., Alarcon-Gonzalez P., Barnes D.M., and Eeles R.A. 2000. The value of rapid functional assays of germline p53 status in LFS and LFL families. Br. J. Cancer 82: 1145.
-
(2000)
Br. J. Cancer
, vol.82
, pp. 1145
-
-
Camplejohn, R.S.1
Sodha, N.2
Gilchrist, R.3
Lomax, M.E.4
Duddy, P.M.5
Miner, C.6
Alarcon-Gonzalez, P.7
Barnes, D.M.8
Eeles, R.A.9
-
7
-
-
0037463328
-
Apoptosis, ageing and cancer susceptibility
-
Camplejohn R.S., Gilchrist R., Easton D., McKenzie-Edwards E., Barnes D.M., Eccles D.M., Ardern-Jones A., Hodgson S.V., Duddy P.M., and Eeles R.A. 2003. Apoptosis, ageing and cancer susceptibility. Br. J. Cancer 88: 487.
-
(2003)
Br. J. Cancer
, vol.88
, pp. 487
-
-
Camplejohn, R.S.1
Gilchrist, R.2
Easton, D.3
McKenzie-Edwards, E.4
Barnes, D.M.5
Eccles, D.M.6
Ardern-Jones, A.7
Hodgson, S.V.8
Duddy, P.M.9
Eeles, R.A.10
-
8
-
-
0028862865
-
Effects of genetic background on tumorigenesis in p53-deficient mice
-
Donehower L.A., Harvey M., Vogel H., McArthur M.J., Montgomery C.A., Jr., Park S.H., Thompson T., Ford R.J., and Bradley A. 1995. Effects of genetic background on tumorigenesis in p53-deficient mice. Mol. Carcinog. 14: 16.
-
(1995)
Mol. Carcinog.
, vol.14
, pp. 16
-
-
Donehower, L.A.1
Harvey, M.2
Vogel, H.3
McArthur, M.J.4
Montgomery Jr., C.A.5
Park, S.H.6
Thompson, T.7
Ford, R.J.8
Bradley, A.9
-
9
-
-
0037372005
-
The codon 72 polymorphic variants of p53 have markedly different apoptotic potential
-
Dumont P., Leu J.I., Della Pietra A.C., III, George D.L., and Murphy M. 2003. The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat. Genet. 33: 357.
-
(2003)
Nat. Genet.
, vol.33
, pp. 357
-
-
Dumont, P.1
Leu, J.I.2
Della Pietra III, A.C.3
George, D.L.4
Murphy, M.5
-
10
-
-
0842310838
-
Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia
-
Emamian E.S., Hall D., Birnbaum M.J., Karayiorgou M., and Gogos J.A. 2004. Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia. Nat. Genet. 36: 131.
-
(2004)
Nat. Genet.
, vol.36
, pp. 131
-
-
Emamian, E.S.1
Hall, D.2
Birnbaum, M.J.3
Karayiorgou, M.4
Gogos, J.A.5
-
11
-
-
4143053880
-
Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation
-
Feng J., Tamaskovic R., Yang Z., Brazil D.P., Merlo A., Hess D., and Hemmings B.A. 2004. Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation. J. Biol. Chem. 279: 35510.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 35510
-
-
Feng, J.1
Tamaskovic, R.2
Yang, Z.3
Brazil, D.P.4
Merlo, A.5
Hess, D.6
Hemmings, B.A.7
-
12
-
-
85047699328
-
Cross-talk between Akt, p53 and Mdm2: Possible implications for the regulation of apoptosis
-
Gottlieb T.M., Leal J.F., Seger R., Taya Y., and Oren M. 2002. Cross-talk between Akt, p53 and Mdm2: Possible implications for the regulation of apoptosis. Oncogene 21: 1299.
-
(2002)
Oncogene
, vol.21
, pp. 1299
-
-
Gottlieb, T.M.1
Leal, J.F.2
Seger, R.3
Taya, Y.4
Oren, M.5
-
13
-
-
13844313862
-
Whole-genome patterns of common DNA variation in three human populations
-
Hinds D.A., Stuve L.L., Nilsen G.B., Halperin E., Eskin E., Ballinger D.G., Frazer K.A., and Cox D.R. 2005. Whole-genome patterns of common DNA variation in three human populations. Science 307: 1072.
-
(2005)
Science
, vol.307
, pp. 1072
-
-
Hinds, D.A.1
Stuve, L.L.2
Nilsen, G.B.3
Halperin, E.4
Eskin, E.5
Ballinger, D.G.6
Frazer, K.A.7
Cox, D.R.8
-
14
-
-
0345269984
-
Germline p53 mutations in a cohort with childhood sarcoma: Sex differences in cancer risk
-
Hwang S.J., Lozano G., Amos C.I., and Strong L.C. 2003. Germline p53 mutations in a cohort with childhood sarcoma: Sex differences in cancer risk. Am. J. Hum. Genet. 72: 975.
-
(2003)
Am. J. Hum. Genet.
, vol.72
, pp. 975
-
-
Hwang, S.J.1
Lozano, G.2
Amos, C.I.3
Strong, L.C.4
-
15
-
-
13244268800
-
Perp-etrating p53-dependent apoptosis
-
Ihrie R.A. and Attardi L.D. 2004. Perp-etrating p53-dependent apoptosis. Cell Cycle 3: 267.
-
(2004)
Cell Cycle
, vol.3
, pp. 267
-
-
Ihrie, R.A.1
Attardi, L.D.2
-
16
-
-
0242456720
-
Perp is a mediator of p53-dependent apoptosis in diverse cell types
-
Ihrie R.A., Reczek E., Horner J.S., Khachatrian L., Sage J., Jacks T., and Attardi L.D. 2003. Perp is a mediator of p53-dependent apoptosis in diverse cell types. Curr. Biol. 13: 1985.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1985
-
-
Ihrie, R.A.1
Reczek, E.2
Horner, J.S.3
Khachatrian, L.4
Sage, J.5
Jacks, T.6
Attardi, L.D.7
-
17
-
-
17644381260
-
Perp is a p63-regulated gene essential for epithelial integrity
-
Ihrie R.A., Marques M.R., Nguyen B.T., Horner J.S., Papazoglu C., Bronson R.T., Mills A.A., and Attardi L.D. 2005. Perp is a p63-regulated gene essential for epithelial integrity. Cell 120: 843.
-
(2005)
Cell
, vol.120
, pp. 843
-
-
Ihrie, R.A.1
Marques, M.R.2
Nguyen, B.T.3
Horner, J.S.4
Papazoglu, C.5
Bronson, R.T.6
Mills, A.A.7
Attardi, L.D.8
-
18
-
-
0035211073
-
The p53 functional circuit
-
Jin S. and Levine A.J. 2001. The p53 functional circuit. J. Cell Sci. 114: 4139.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 4139
-
-
Jin, S.1
Levine, A.J.2
-
19
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander E.S., Linton L.M., Birren B., Nusbaum C., Zody M.C., Baldwin J., Devon K., Dewar K., Doyle M., FitzHugh W., Funke R., Gage D., Harris K., Heaford A., Howland J., Kann L., Lehoczky J., LeVine R., McEwan P., McKernan K., Meldrim J., Mesirov J.P., Miranda C., Morris W., and Naylor J., et al. (International Human Genome Sequencing Consortium). 2001. Initial sequencing and analysis of the human genome. Nature 409: 860.
-
(2001)
Nature
, vol.409
, pp. 860
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
Devon, K.7
Dewar, K.8
Doyle, M.9
Fitzhugh, W.10
Funke, R.11
Gage, D.12
Harris, K.13
Heaford, A.14
Howland, J.15
Kann, L.16
Lehoczky, J.17
Levine, R.18
McEwan, P.19
McKernan, K.20
Meldrim, J.21
Mesirov, J.P.22
Miranda, C.23
Morris, W.24
Naylor, J.25
more..
-
20
-
-
0025395704
-
Familial cancer syndromes and clusters
-
Li F.P. 1990. Familial cancer syndromes and clusters. Curr. Probl. Cancer 14: 73.
-
(1990)
Curr. Probl. Cancer
, vol.14
, pp. 73
-
-
Li, F.P.1
-
21
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe S.W., Schmitt E.M., Smith S.W., Osborne B.A., and Jacks T. 1993. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847.
-
(1993)
Nature
, vol.362
, pp. 847
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
22
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
Malkin D., Li F.P., Strong L.C., Fraumeni J.F., Jr., Nelson C.E., Kim D.H., Kassel J., Gryka M.A., Bischoff F.Z., and Tainsky M.A., et al. 1990. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250: 1233-8.
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
Li, F.P.2
Strong, L.C.3
Fraumeni Jr., J.F.4
Nelson, C.E.5
Kim, D.H.6
Kassel, J.7
Gryka, M.A.8
Bischoff, F.Z.9
Tainsky, M.A.10
-
23
-
-
0034063604
-
A common polymorphism acts as an intragenic modifier of mutant p53 behaviour
-
Marin M.C., Jost C.A., Brooks L.A., Irwin M.S., O'Nions J., Tidy J.A., James N., McGregor J.M., Harwood C.A., Yulug I.G., Vousden K.H., Allday M.J., Gusterson B., Ikawa S., Hinds P.W., Crook T., and Kaelin W.G., Jr. 2000. A common polymorphism acts as an intragenic modifier of mutant p53 behaviour. Nat. Genet. 25: 47.
-
(2000)
Nat. Genet.
, vol.25
, pp. 47
-
-
Marin, M.C.1
Jost, C.A.2
Brooks, L.A.3
Irwin, M.S.4
O'Nions, J.5
Tidy, J.A.6
James, N.7
McGregor, J.M.8
Harwood, C.A.9
Yulug, I.G.10
Vousden, K.H.11
Allday, M.J.12
Gusterson, B.13
Ikawa, S.14
Hinds, P.W.15
Crook, T.16
Kaelin Jr., W.G.17
-
24
-
-
0035949588
-
A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
-
Mayo L.D. and Donner D.B. 2001. A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus. Proc. Natl. Acad. Sci. 98: 11598.
-
(2001)
Proc. Natl. Acad. Sci.
, vol.98
, pp. 11598
-
-
Mayo, L.D.1
Donner, D.B.2
-
25
-
-
11844288913
-
Perp is required for tissue-specific cell survival during zebrafish development
-
Nowak M., Koster C., and Hammerschmidt M. 2005. Perp is required for tissue-specific cell survival during zebrafish development. Cell Death Differ. 12: 52.
-
(2005)
Cell Death Differ.
, vol.12
, pp. 52
-
-
Nowak, M.1
Koster, C.2
Hammerschmidt, M.3
-
26
-
-
0037077230
-
Akt enhances Mdm2-mediated ubiquitination and degradation of p53
-
Ogawara Y., Kishishita S., Obata T., Isazawa Y., Suzuki T., Tanaka K., Masuyama N., and Gotoh Y. 2002. Akt enhances Mdm2-mediated ubiquitination and degradation of p53. J. Biol. Chem. 277: 21843.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21843
-
-
Ogawara, Y.1
Kishishita, S.2
Obata, T.3
Isazawa, Y.4
Suzuki, T.5
Tanaka, K.6
Masuyama, N.7
Gotoh, Y.8
-
27
-
-
0035865322
-
A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
-
Sachidanandam R., Weissman D., Schmidt S.C., Kakol J.M., Stein L.D., Marth G., Sherry S., Mullikin J.C., Mortimore B.J., Willey D.L., Hunt S.E., Cole C.G., Coggill P.C., Rice C.M., Ning Z., Rogers J., Bentley D.R., Kwok P.Y., Mardis E.R., Yeh R.T., Schultz B., Cook L., Davenport R., Dante M., and Fulton L., et al. (International SNP Map Working Group). 2001. A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature 409: 928.
-
(2001)
Nature
, vol.409
, pp. 928
-
-
Sachidanandam, R.1
Weissman, D.2
Schmidt, S.C.3
Kakol, J.M.4
Stein, L.D.5
Marth, G.6
Sherry, S.7
Mullikin, J.C.8
Mortimore, B.J.9
Willey, D.L.10
Hunt, S.E.11
Cole, C.G.12
Coggill, P.C.13
Rice, C.M.14
Ning, Z.15
Rogers, J.16
Bentley, D.R.17
Kwok, P.Y.18
Mardis, E.R.19
Yeh, R.T.20
Schultz, B.21
Cook, L.22
Davenport, R.23
Dante, M.24
Fulton, L.25
more..
-
28
-
-
0035751937
-
Assessing TP53 status in human tumours to evaluate clinical outcome
-
Soussi T. and Beroud C. 2001. Assessing TP53 status in human tumours to evaluate clinical outcome. Nat. Rev. Cancer 1: 233.
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 233
-
-
Soussi, T.1
Beroud, C.2
-
29
-
-
0035895505
-
The sequence of the human genome
-
Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H., Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., and Nelson C., et al. 2001. The sequence of the human genome. Science 291: 1304.
-
(2001)
Science
, vol.291
, pp. 1304
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
Smith, H.O.7
Yandell, M.8
Evans, C.A.9
Holt, R.A.10
Gocayne, J.D.11
Amanatides, P.12
Ballew, R.M.13
Huson, D.H.14
Wortman, J.R.15
Zhang, Q.16
Kodira, C.D.17
Zheng, X.H.18
Chen, L.19
Skupski, M.20
Subramanian, G.21
Thomas, P.D.22
Zhang, J.23
Gabor Miklos, G.L.24
Nelson, C.25
more..
-
31
-
-
0035736487
-
HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
-
Zhou B.P., Liao Y., Xia W., Zou Y., Spohn B., and Hung M.C. 2001. HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation. Nat. Cell Biol. 3: 973.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 973
-
-
Zhou, B.P.1
Liao, Y.2
Xia, W.3
Zou, Y.4
Spohn, B.5
Hung, M.C.6
|