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Volumn 84, Issue 2, 2006, Pages 389-397

Gαs sensitizes human SH-SY5Y cells to apoptosis independently of the protein kinase A pathway

Author keywords

Apoptosis; Bipolar disorder; Cellular stress; G protein; Protein kinase A

Indexed keywords

ADENOSINE 3' 5' CYCLIC MONOPHOSPHOROTHIOATE; BENZYLOXYCARBONYL VALYL ALANYL ASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE INHIBITOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP DERIVATIVE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; HOE 33342; KT 5720; UNCLASSIFIED DRUG; CASP3 PROTEIN, HUMAN; CASPASE; CYCLIC AMP; DRUG DERIVATIVE; ENZYME INHIBITOR;

EID: 33746400092     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.20875     Document Type: Article
Times cited : (6)

References (53)
  • 1
    • 0026831726 scopus 로고
    • The involvement of guanine nucleotide binding proteins in the pathogenesis and treatment of affective disorders
    • Avissar S, Schreiber G. 1992. The involvement of guanine nucleotide binding proteins in the pathogenesis and treatment of affective disorders. Biol Psychiatry 31:435-459.
    • (1992) Biol Psychiatry , vol.31 , pp. 435-459
    • Avissar, S.1    Schreiber, G.2
  • 2
    • 0032527572 scopus 로고    scopus 로고
    • A reduction of nonpyramidal cells in sector CA2 of schizophrenics and manic depressives
    • Benes FM, Kwok EW, Vincent SL, Todtenkopf MS. 1998. A reduction of nonpyramidal cells in sector CA2 of schizophrenics and manic depressives. Biol Psychiatry 44:88-97.
    • (1998) Biol Psychiatry , vol.44 , pp. 88-97
    • Benes, F.M.1    Kwok, E.W.2    Vincent, S.L.3    Todtenkopf, M.S.4
  • 3
    • 0032521673 scopus 로고    scopus 로고
    • s-induced neurodegeneration in Caenorhabditis elegans
    • s-induced neurodegeneration in Caenorhabditis elegans. J Neurosci 18:2871-2880.
    • (1998) J Neurosci , vol.18 , pp. 2871-2880
    • Berger, A.J.1    Hart, A.C.2    Kaplan, J.M.3
  • 5
    • 0030788099 scopus 로고    scopus 로고
    • Characterization of the cell death process induced by staurosporine in human neuroblastoma cell lines
    • Boix J, Llecha N, Yuste V-J, Comella JX. 1997. Characterization of the cell death process induced by staurosporine in human neuroblastoma cell lines. Neuropharmacology 36:811-821.
    • (1997) Neuropharmacology , vol.36 , pp. 811-821
    • Boix, J.1    Llecha, N.2    Yuste, V.-J.3    Comella, J.X.4
  • 6
    • 0016669563 scopus 로고
    • Selection of a variant lymphoma cell deficient in adenylate cyclase
    • Bourne HR, Coffino P, Tomkins GM. 1975. Selection of a variant lymphoma cell deficient in adenylate cyclase. Science 187:750-752.
    • (1975) Science , vol.187 , pp. 750-752
    • Bourne, H.R.1    Coffino, P.2    Tomkins, G.M.3
  • 7
    • 0037317158 scopus 로고    scopus 로고
    • Altered cAMP-dependent protein kinase subunit immunolabeling in post-mortem brain from patients with bipolar affective disorder
    • Chang A, Li PP, Warsh JJ. 2003. Altered cAMP-dependent protein kinase subunit immunolabeling in post-mortem brain from patients with bipolar affective disorder. J Neurochem 84:781-791.
    • (2003) J Neurochem , vol.84 , pp. 781-791
    • Chang, A.1    Li, P.P.2    Warsh, J.J.3
  • 8
    • 0024522783 scopus 로고
    • Cholera toxin induces cAMP-independent degradation of Gs
    • Chang FH, Bourne HR. 1989. Cholera toxin induces cAMP-independent degradation of Gs. J Biol Chem 264:5352-5357.
    • (1989) J Biol Chem , vol.264 , pp. 5352-5357
    • Chang, F.H.1    Bourne, H.R.2
  • 9
    • 0035195434 scopus 로고    scopus 로고
    • Sα) in proliferation of PC-3M prostate cancer cells
    • Sα) in proliferation of PC-3M prostate cancer cells. Int J Cancer 91:46-54.
    • (2001) Int J Cancer , vol.91 , pp. 46-54
    • Chien, J.1    Shah, G.V.2
  • 11
    • 0032844695 scopus 로고    scopus 로고
    • Increased cyclic AMP-dependent protein kinase activity in postmortem brain from patients with bipolar affective disorder
    • Fields A, Li PP, Kish SJ, Warsh JJ. 1999. Increased cyclic AMP-dependent protein kinase activity in postmortem brain from patients with bipolar affective disorder. J Neurochem 73:1704-1710.
    • (1999) J Neurochem , vol.73 , pp. 1704-1710
    • Fields, A.1    Li, P.P.2    Kish, S.J.3    Warsh, J.J.4
  • 12
    • 0029796167 scopus 로고    scopus 로고
    • Receptor-mediated activation of G proteins is increased in postmortem brains of bipolar affective disorder subjects
    • Friedman E, Wang HY. 1996. Receptor-mediated activation of G proteins is increased in postmortem brains of bipolar affective disorder subjects. J Neurochem 67:1145-1152.
    • (1996) J Neurochem , vol.67 , pp. 1145-1152
    • Friedman, E.1    Wang, H.Y.2
  • 13
    • 0028141937 scopus 로고
    • Genomic effects of the putative oncogene Gαs. Chronic transcriptional activation of the c-fos proto-oncogene in endocrine cells
    • Gaiddon C, Boutillier A, Monnier D, Mercken L, Loeffler J. 1994. Genomic effects of the putative oncogene Gαs. Chronic transcriptional activation of the c-fos proto-oncogene in endocrine cells. J Biol Chem 269:22663-22671.
    • (1994) J Biol Chem , vol.269 , pp. 22663-22671
    • Gaiddon, C.1    Boutillier, A.2    Monnier, D.3    Mercken, L.4    Loeffler, J.5
  • 16
    • 4544342085 scopus 로고    scopus 로고
    • New insights help define the pathophysiology of bipolar affective disorder: Neuroimaging and neuropathology findings
    • Haldane M, Frangou S. 2004. New insights help define the pathophysiology of bipolar affective disorder: neuroimaging and neuropathology findings. Prog Neuropsychopharmacol Biol Psychiatry 28:943-960.
    • (2004) Prog Neuropsychopharmacol Biol Psychiatry , vol.28 , pp. 943-960
    • Haldane, M.1    Frangou, S.2
  • 17
    • 0025328057 scopus 로고
    • Reduction of adenylyl cyclase activity by cholera toxin in myeloid cells: Long-term down-regulation of Gsα subunits by cholera toxin treatment
    • Hermouet S, Milligan G, Lanotte M. 1990. Reduction of adenylyl cyclase activity by cholera toxin in myeloid cells: Long-term down-regulation of Gsα subunits by cholera toxin treatment. FEBS Lett 267:221-225.
    • (1990) FEBS Lett , vol.267 , pp. 221-225
    • Hermouet, S.1    Milligan, G.2    Lanotte, M.3
  • 19
    • 0034280096 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in bipolar disorder
    • Kato T, Kato N. 2000. Mitochondrial dysfunction in bipolar disorder. Bipolar Disord 2:180-190.
    • (2000) Bipolar Disord , vol.2 , pp. 180-190
    • Kato, T.1    Kato, N.2
  • 20
    • 0030969879 scopus 로고    scopus 로고
    • An activating mutation in a Caenorhabditis elegans Gs protein induces neural degeneration
    • Korswagen HC, Park JH, Ohshima Y, Plasterk RH. 1997. An activating mutation in a Caenorhabditis elegans Gs protein induces neural degeneration. Genes Dev 11:1493-1503.
    • (1997) Genes Dev , vol.11 , pp. 1493-1503
    • Korswagen, H.C.1    Park, J.H.2    Ohshima, Y.3    Plasterk, R.H.4
  • 21
    • 0032167376 scopus 로고    scopus 로고
    • G protein hyperactivation of the Caenorhabditis elegans adenylyl cyclase SGS-1 induces neuronal degeneration
    • Korswagen HC, van der Linden AM, Plasterk RH. 1998. G protein hyperactivation of the Caenorhabditis elegans adenylyl cyclase SGS-1 induces neuronal degeneration. EMBO J 17:5059-5065.
    • (1998) EMBO J , vol.17 , pp. 5059-5065
    • Korswagen, H.C.1    Van Der Linden, A.M.2    Plasterk, R.H.3
  • 22
    • 0026474549 scopus 로고
    • Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity
    • Levis MJ, Bourne HR. 1992. Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity. J Cell Biol 119:1297-1307.
    • (1992) J Cell Biol , vol.119 , pp. 1297-1307
    • Levis, M.J.1    Bourne, H.R.2
  • 23
    • 0141953294 scopus 로고    scopus 로고
    • Activation of stimulatory heterotrimeric G proteins increases glutathione and protects neuronal cells against oxidative stress
    • Lewerenz J, Letz J, Methner A. 2003. Activation of stimulatory heterotrimeric G proteins increases glutathione and protects neuronal cells against oxidative stress. J Neurochem 87:522-531.
    • (2003) J Neurochem , vol.87 , pp. 522-531
    • Lewerenz, J.1    Letz, J.2    Methner, A.3
  • 25
    • 0034268796 scopus 로고    scopus 로고
    • Src tyrosine kinase is a novel direct effector of G proteins
    • Ma YC, Huang J, Ali S, Lowry W, Huang XY. 2000. Src tyrosine kinase is a novel direct effector of G proteins. Cell 102:635-646.
    • (2000) Cell , vol.102 , pp. 635-646
    • Ma, Y.C.1    Huang, J.2    Ali, S.3    Lowry, W.4    Huang, X.Y.5
  • 27
    • 13144305132 scopus 로고    scopus 로고
    • Chronic stress alters synaptic terminal structure in hippocampus
    • Magarinos AM, Verdugo JM, McEwen BS. 1997. Chronic stress alters synaptic terminal structure in hippocampus. Proc Natl Acad Sci U S A 94:14002-14008.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 14002-14008
    • Magarinos, A.M.1    Verdugo, J.M.2    McEwen, B.S.3
  • 28
    • 0035295487 scopus 로고    scopus 로고
    • Impairments of neuroplasticity and cellular resilience in severe mood disorders: Implications for the development of novel therapeutics
    • Manji HK, Duman RS. 2001. Impairments of neuroplasticity and cellular resilience in severe mood disorders: implications for the development of novel therapeutics. Psychopharmacol Bull 35:5-49.
    • (2001) Psychopharmacol Bull , vol.35 , pp. 5-49
    • Manji, H.K.1    Duman, R.S.2
  • 29
    • 0028942060 scopus 로고
    • Guanine nucleotide-binding proteins in bipolar affective disorder. Effects of long-term lithium treatment
    • Manji HK, Chen G, Shimon H, Hsiao JK, Potter WZ, Belmaker RH. 1995. Guanine nucleotide-binding proteins in bipolar affective disorder. Effects of long-term lithium treatment. Arch Gen Psychiatry 52:135-144.
    • (1995) Arch Gen Psychiatry , vol.52 , pp. 135-144
    • Manji, H.K.1    Chen, G.2    Shimon, H.3    Hsiao, J.K.4    Potter, W.Z.5    Belmaker, R.H.6
  • 30
    • 0035370949 scopus 로고    scopus 로고
    • Intracellular signaling from the endoplasmic reticulum to the nucleus: The unfolded protein response in yeast and mammals
    • Patil C, Walter P. 2001. Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals. Curr Opin Cell Biol 13:349-355.
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 349-355
    • Patil, C.1    Walter, P.2
  • 31
    • 0031011697 scopus 로고    scopus 로고
    • Characterization of CPP32-like protease activity following apoptotic challenge in SH-SY5Y neuroblastoma cells
    • Posmantur R, McGinnis K, Nadimpalli R, Gilbertsen RB, Wang KK. 1997. Characterization of CPP32-like protease activity following apoptotic challenge in SH-SY5Y neuroblastoma cells. J Neurochem 68:2328-2337.
    • (1997) J Neurochem , vol.68 , pp. 2328-2337
    • Posmantur, R.1    McGinnis, K.2    Nadimpalli, R.3    Gilbertsen, R.B.4    Wang, K.K.5
  • 32
  • 34
    • 0036102199 scopus 로고    scopus 로고
    • Cell pathology in bipolar disorder
    • Rajkowska G. 2002. Cell pathology in bipolar disorder. Bipolar Disord 4:105-116.
    • (2002) Bipolar Disord , vol.4 , pp. 105-116
    • Rajkowska, G.1
  • 37
    • 0025851833 scopus 로고
    • Hyperfunctional G proteins in mononuclear leukocytes of patients with mania
    • Schreiber G, Avissar S, Danon A, Belmaker RH. 1991. Hyperfunctional G proteins in mononuclear leukocytes of patients with mania. Biol Psychiatry 29:273-280.
    • (1991) Biol Psychiatry , vol.29 , pp. 273-280
    • Schreiber, G.1    Avissar, S.2    Danon, A.3    Belmaker, R.H.4
  • 38
    • 27144492384 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in bipolar disorder: Evidence from magnetic resonance spectroscopy research
    • doi:10
    • Stork C, Renshaw PF. 2005. Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy research. Mol Psychiatry doi:10:900-919.
    • (2005) Mol Psychiatry , pp. 900-919
    • Stork, C.1    Renshaw, P.F.2
  • 39
    • 12344250469 scopus 로고    scopus 로고
    • The functional neuroanatomy of bipolar disorder: A review of neuroimaging findings
    • Strakowski SM, Delbello MP, Adler CM. 2005. The functional neuroanatomy of bipolar disorder: a review of neuroimaging findings. Mol Psychiatry 10:105-116.
    • (2005) Mol Psychiatry , vol.10 , pp. 105-116
    • Strakowski, S.M.1    Delbello, M.P.2    Adler, C.M.3
  • 42
    • 0033527747 scopus 로고    scopus 로고
    • sα repression of adipogenesis via Syk
    • sα repression of adipogenesis via Syk. J Biol Chem 274:32159-32166.
    • (1999) J Biol Chem , vol.274 , pp. 32159-32166
    • Wang, H.1    Malbon, C.C.2
  • 43
    • 0030614506 scopus 로고    scopus 로고
    • 2+-calmodulin-sensitive protein kinase type II is obligate for adipogenesis
    • 2+-calmodulin-sensitive protein kinase type II is obligate for adipogenesis. J Biol Chem 272:1817-1821.
    • (1997) J Biol Chem , vol.272 , pp. 1817-1821
    • Wang, H.1    Goligorsky, M.S.2    Malbon, C.C.3
  • 44
    • 0002570996 scopus 로고    scopus 로고
    • Guanine nucleotide binding protein disturbances in bipolar disorder
    • Manji HK, Bowden C, Belmaker RH, editors. Washington, DC: American Psychiatric Association Press
    • Warsh JJ, Young LT, Li PP. 2000. Guanine nucleotide binding protein disturbances in bipolar disorder. In: Manji HK, Bowden C, Belmaker RH, editors. Bipolar medications: mechanisms of action. Washington, DC: American Psychiatric Association Press. p 299-329.
    • (2000) Bipolar Medications: Mechanisms of Action , pp. 299-329
    • Warsh, J.J.1    Young, L.T.2    Li, P.P.3
  • 45
    • 13344283407 scopus 로고    scopus 로고
    • Role of intracellular calcium signaling in the pathophysiology and pharmacotherapy of bipolar disorder: Current status
    • Warsh JJ, Andreopoulos S, Li PP. 2004. Role of intracellular calcium signaling in the pathophysiology and pharmacotherapy of bipolar disorder: current status. Clin Neurosci Res 4:201-213.
    • (2004) Clin Neurosci Res , vol.4 , pp. 201-213
    • Warsh, J.J.1    Andreopoulos, S.2    Li, P.P.3
  • 46
    • 0026781307 scopus 로고
    • Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons
    • Watanabe Y, Gould E, McEwen BS. 1992. Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons. Brain Res 588:341-345.
    • (1992) Brain Res , vol.588 , pp. 341-345
    • Watanabe, Y.1    Gould, E.2    McEwen, B.S.3
  • 47
    • 0035889662 scopus 로고    scopus 로고
    • Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration
    • Wellman CL. 2001. Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration. J Neurobiol 49:245-253.
    • (2001) J Neurobiol , vol.49 , pp. 245-253
    • Wellman, C.L.1
  • 48
    • 0028144079 scopus 로고
    • Effects of restraint stress on components of adenylyl cyclase signal transduction in the rat hippocampus
    • Wolfgang D, Chen I, Wand GS. 1994. Effects of restraint stress on components of adenylyl cyclase signal transduction in the rat hippocampus. Neuropsychopharmacology 11:187-193.
    • (1994) Neuropsychopharmacology , vol.11 , pp. 187-193
    • Wolfgang, D.1    Chen, I.2    Wand, G.S.3
  • 51
    • 0023758453 scopus 로고
    • 2+ channels. Evidence for direct regulation independent of phosphorylation by cAMP-dependent protein kinase or stimulation by a dihydropyridine agonist
    • 2+ channels. Evidence for direct regulation independent of phosphorylation by cAMP-dependent protein kinase or stimulation by a dihydropyridine agonist. J Biol Chem 263:9887-9895.
    • (1988) J Biol Chem , vol.263 , pp. 9887-9895
    • Yatani, A.1    Imoto, Y.2    Codina, J.3    Hamilton, S.L.4    Brown, A.M.5    Birnbaumer, L.6


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