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Volumn 42, Issue 11, 2006, Pages 1520-1529

Cytogenetics and molecular cytogenetics in multiple myeloma

Author keywords

Chromosome banding; Comparative genomic hybridization (CGH); Fluorescence in situ hybridization (FISH); Hyperdiploidy; IgH Translocation; Multiple myeloma; Paraproteinemias

Indexed keywords

ANEUPLOIDY; ARTICLE; CELL SELECTION; CHROMOSOME 13Q; CHROMOSOME 17P; CHROMOSOME 1Q; CHROMOSOME 21; CHROMOSOME 5; CHROMOSOME 7; CHROMOSOME 9; CHROMOSOME ABERRATION; CYTOGENETICS; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DELETION; GENE FREQUENCY; GENE TRANSLOCATION; GENOMICS; HUMAN; METHODOLOGY; MOLECULAR GENETICS; MONOSOMY; MULTIPLE MYELOMA; ONCOGENE; PATHOGENESIS; PRIORITY JOURNAL; TRISOMY;

EID: 33746362589     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2005.12.028     Document Type: Article
Times cited : (60)

References (104)
  • 1
    • 0033025034 scopus 로고    scopus 로고
    • Syndecan-1 (CD 138) in myeloma and lymphoid malignancies: a multifunctional regulator of cell behavior within the tumour microenvironment
    • Dhodapkar M.V., and Sanderson R.D. Syndecan-1 (CD 138) in myeloma and lymphoid malignancies: a multifunctional regulator of cell behavior within the tumour microenvironment. Leuk Lymphoma 34 (1999) 35-43
    • (1999) Leuk Lymphoma , vol.34 , pp. 35-43
    • Dhodapkar, M.V.1    Sanderson, R.D.2
  • 2
    • 0031929051 scopus 로고    scopus 로고
    • The myeloma cell antigen syndecan-1 is lost by apoptotic myeloma cells
    • Jourdan M., Ferlin M., Legouffe E., et al. The myeloma cell antigen syndecan-1 is lost by apoptotic myeloma cells. Br J Haematol 100 (1998) 637-646
    • (1998) Br J Haematol , vol.100 , pp. 637-646
    • Jourdan, M.1    Ferlin, M.2    Legouffe, E.3
  • 3
    • 20244363331 scopus 로고    scopus 로고
    • Chromosome abnormalities clustering and its implications for pathogenesis and prognosis in myeloma
    • Debes-Marun C., Dewald G., Bryant S., et al. Chromosome abnormalities clustering and its implications for pathogenesis and prognosis in myeloma. Leukemia 17 (2003) 427-436
    • (2003) Leukemia , vol.17 , pp. 427-436
    • Debes-Marun, C.1    Dewald, G.2    Bryant, S.3
  • 6
    • 0027195801 scopus 로고
    • Karyotype in multiple myeloma and plasma cell leukaemia
    • Weh H.J., Gutensohn K., Selbach J., et al. Karyotype in multiple myeloma and plasma cell leukaemia. Eur J Cancer 29A (1993) 1269-1273
    • (1993) Eur J Cancer , vol.29 A , pp. 1269-1273
    • Weh, H.J.1    Gutensohn, K.2    Selbach, J.3
  • 8
    • 0028947460 scopus 로고
    • Improved cytogenetics in multiple myeloma: a study of 151 patients including 117 patients at diagnosis
    • Lai J.L., Zandecki M., Mary J.Y., et al. Improved cytogenetics in multiple myeloma: a study of 151 patients including 117 patients at diagnosis. Blood 85 (1995) 2490-2497
    • (1995) Blood , vol.85 , pp. 2490-2497
    • Lai, J.L.1    Zandecki, M.2    Mary, J.Y.3
  • 9
    • 0030211192 scopus 로고    scopus 로고
    • Multiple myeloma: almost all patients are cytogenetically abnormal
    • Zandecki M., Lai J.L., and Facon T. Multiple myeloma: almost all patients are cytogenetically abnormal. Br J Haematol 94 (1996) 217-227
    • (1996) Br J Haematol , vol.94 , pp. 217-227
    • Zandecki, M.1    Lai, J.L.2    Facon, T.3
  • 10
    • 0030825598 scopus 로고    scopus 로고
    • Hypodiploidy and 22q11 rearrangements at diagnosis are associated with poor prognosis in patients with multiple myeloma
    • Calasanz M.J., Cigudosa J.C., Odero M.D., et al. Hypodiploidy and 22q11 rearrangements at diagnosis are associated with poor prognosis in patients with multiple myeloma. Br J Haematol 98 (1997) 418-425
    • (1997) Br J Haematol , vol.98 , pp. 418-425
    • Calasanz, M.J.1    Cigudosa, J.C.2    Odero, M.D.3
  • 11
    • 17144433568 scopus 로고    scopus 로고
    • Unique role of cytogenetics in the prognosis of patients with myeloma receiving high-dose therapy and autotransplants
    • Tricot G., Sawyer J.R., Jagannath S., et al. Unique role of cytogenetics in the prognosis of patients with myeloma receiving high-dose therapy and autotransplants. J Clin Oncol 15 (1997) 2659-2666
    • (1997) J Clin Oncol , vol.15 , pp. 2659-2666
    • Tricot, G.1    Sawyer, J.R.2    Jagannath, S.3
  • 12
    • 0030922231 scopus 로고    scopus 로고
    • Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3.
    • Chesi M., Nardini E., Brents L.A., et al. Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3. Nat Genet 16 (1997) 260-264
    • (1997) Nat Genet , vol.16 , pp. 260-264
    • Chesi, M.1    Nardini, E.2    Brents, L.A.3
  • 13
    • 0031839633 scopus 로고    scopus 로고
    • Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma
    • Chesi M., Bergsagel P.L., Shonukan O.O., et al. Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma. Blood 91 (1998) 4457-4463
    • (1998) Blood , vol.91 , pp. 4457-4463
    • Chesi, M.1    Bergsagel, P.L.2    Shonukan, O.O.3
  • 14
    • 0032402134 scopus 로고    scopus 로고
    • Identification of new nonrandom translocations in multiple myeloma with multicolour spectral karyotyping
    • Sawyer J.R., Lukacs J.L., Munshi N., et al. Identification of new nonrandom translocations in multiple myeloma with multicolour spectral karyotyping. Blood 92 (1998) 4269-4278
    • (1998) Blood , vol.92 , pp. 4269-4278
    • Sawyer, J.R.1    Lukacs, J.L.2    Munshi, N.3
  • 15
    • 0032889633 scopus 로고    scopus 로고
    • High incidence of cryptic translocations involving the Ig heavy chain gene in multiple myeloma, as shown by fluorescence in situ hybridization
    • Avet-Loiseau H., Brigaudeau C., Morineau N., et al. High incidence of cryptic translocations involving the Ig heavy chain gene in multiple myeloma, as shown by fluorescence in situ hybridization. Genes Chromosomes Cancer 24 (1999) 9-15
    • (1999) Genes Chromosomes Cancer , vol.24 , pp. 9-15
    • Avet-Loiseau, H.1    Brigaudeau, C.2    Morineau, N.3
  • 16
    • 0032522947 scopus 로고    scopus 로고
    • Characterization of nonrandom chromosomal gains and losses in multiple myeloma by comparative genomic hybridization
    • Cigudosa J.C., Rao P.H., Calasanz M.J., et al. Characterization of nonrandom chromosomal gains and losses in multiple myeloma by comparative genomic hybridization. Blood 91 (1998) 3007-3010
    • (1998) Blood , vol.91 , pp. 3007-3010
    • Cigudosa, J.C.1    Rao, P.H.2    Calasanz, M.J.3
  • 17
    • 0032532610 scopus 로고    scopus 로고
    • Detection of nonrandom chromosomal changes in multiple myeloma by comparative genomic hybridization
    • Avet-Loiseau H., and Bataille R. Detection of nonrandom chromosomal changes in multiple myeloma by comparative genomic hybridization. Blood 92 (1998) 2997-2998
    • (1998) Blood , vol.92 , pp. 2997-2998
    • Avet-Loiseau, H.1    Bataille, R.2
  • 18
  • 19
    • 0038824961 scopus 로고    scopus 로고
    • Value of Comparative Genomic Hybridization (CGH) and Fluorescence in situ Hybridization (FISH) for molecular diagnostics in multiple myeloma
    • Liebisch P., Viardot A., Bassermann N., et al. Value of Comparative Genomic Hybridization (CGH) and Fluorescence in situ Hybridization (FISH) for molecular diagnostics in multiple myeloma. Br J Haematol 122 (2003) 193-201
    • (2003) Br J Haematol , vol.122 , pp. 193-201
    • Liebisch, P.1    Viardot, A.2    Bassermann, N.3
  • 20
    • 7244234267 scopus 로고    scopus 로고
    • Prognostic and biologic significance of chromosomal imbalances assessed by comparative genomic hybridization in multiple myeloma
    • Gutierrez N.C., Garcia J.L., Hernandez J.M., et al. Prognostic and biologic significance of chromosomal imbalances assessed by comparative genomic hybridization in multiple myeloma. Blood 104 (2004) 2661-2666
    • (2004) Blood , vol.104 , pp. 2661-2666
    • Gutierrez, N.C.1    Garcia, J.L.2    Hernandez, J.M.3
  • 21
    • 9644263895 scopus 로고    scopus 로고
    • Frequent gains of the short arm of chromosome 9 in multiple myeloma with normal G-banded karyotype detected by comparative genomic hybridization
    • Tchinda J., Volpert S., Kropff M., et al. Frequent gains of the short arm of chromosome 9 in multiple myeloma with normal G-banded karyotype detected by comparative genomic hybridization. Am J Clin Pathol 122 (2004) 875-882
    • (2004) Am J Clin Pathol , vol.122 , pp. 875-882
    • Tchinda, J.1    Volpert, S.2    Kropff, M.3
  • 22
    • 0030701970 scopus 로고    scopus 로고
    • Matrix-based comparative genomic hybridization: biochips to screen for genomic imbalances
    • Solinas-Toldo S., Lampel S., Stilgenbauer S., et al. Matrix-based comparative genomic hybridization: biochips to screen for genomic imbalances. Genes Chromosomes Cancer 20 (1997) 399-407
    • (1997) Genes Chromosomes Cancer , vol.20 , pp. 399-407
    • Solinas-Toldo, S.1    Lampel, S.2    Stilgenbauer, S.3
  • 23
    • 33746353741 scopus 로고    scopus 로고
    • Automated screening for genomic imbalances in multiple myeloma using microarray-based comparative genomic hybridization (M-CGH)
    • abstr; suppl 2
    • Wendl C., Radlwimmer B., Wessendorf S., et al. Automated screening for genomic imbalances in multiple myeloma using microarray-based comparative genomic hybridization (M-CGH). Haematologica 90 (2005) 150 abstr; suppl 2
    • (2005) Haematologica , vol.90 , pp. 150
    • Wendl, C.1    Radlwimmer, B.2    Wessendorf, S.3
  • 24
    • 8944237001 scopus 로고    scopus 로고
    • Incidence of chromosome numerical changes in multiple myeloma: fluorescence in situ hybridization analysis using 15 chromosome-specific probes
    • Tabernero D., San Miguel J.F., Garcia-Sanz M., et al. Incidence of chromosome numerical changes in multiple myeloma: fluorescence in situ hybridization analysis using 15 chromosome-specific probes. Am J Pathol 149 (1996) 153-161
    • (1996) Am J Pathol , vol.149 , pp. 153-161
    • Tabernero, D.1    San Miguel, J.F.2    Garcia-Sanz, M.3
  • 26
    • 0029124130 scopus 로고
    • Multiple myeloma: high incidence of chromosomal aneuploidy as detected by interphase fluorescence in situ hybridization
    • Drach J., Schuster J., Nowotny H., et al. Multiple myeloma: high incidence of chromosomal aneuploidy as detected by interphase fluorescence in situ hybridization. Cancer Res 55 (1995) 3854-3859
    • (1995) Cancer Res , vol.55 , pp. 3854-3859
    • Drach, J.1    Schuster, J.2    Nowotny, H.3
  • 27
    • 0028884252 scopus 로고
    • Interphase fluorescence in situ hybridization identifies chromosomal abnormalities in plasma cells from patients with monoclonal gammopathy of undetermined significance
    • Drach J., Angerler J., Schuster J., et al. Interphase fluorescence in situ hybridization identifies chromosomal abnormalities in plasma cells from patients with monoclonal gammopathy of undetermined significance. Blood 86 (1995) 3915-3921
    • (1995) Blood , vol.86 , pp. 3915-3921
    • Drach, J.1    Angerler, J.2    Schuster, J.3
  • 28
    • 0037103287 scopus 로고    scopus 로고
    • Genomic abnormalities in monoclonal gammopathy of undetermined significance
    • Fonseca R., Bailey R.J., Ahmann G.J., et al. Genomic abnormalities in monoclonal gammopathy of undetermined significance. Blood 100 (2002) 1417-1424
    • (2002) Blood , vol.100 , pp. 1417-1424
    • Fonseca, R.1    Bailey, R.J.2    Ahmann, G.J.3
  • 30
    • 24744434736 scopus 로고    scopus 로고
    • A validated FISH trisomy index demonstrates the hyperdiploid and nonhyperdiploid dichotomy in MGUS
    • Chng W.J., Van Wier S.A., Ahmann G.J., et al. A validated FISH trisomy index demonstrates the hyperdiploid and nonhyperdiploid dichotomy in MGUS. Blood 106 (2005) 2156-2161
    • (2005) Blood , vol.106 , pp. 2156-2161
    • Chng, W.J.1    Van Wier, S.A.2    Ahmann, G.J.3
  • 31
    • 0032005528 scopus 로고    scopus 로고
    • A novel three-colour, clone-specific fluorescence in situ hybridization procedure for monoclonal gammopathies
    • Ahmann G.J., Jalal S.M., Juneau A.L., et al. A novel three-colour, clone-specific fluorescence in situ hybridization procedure for monoclonal gammopathies. Cancer Genet Cytogenet 101 (1998) 7-11
    • (1998) Cancer Genet Cytogenet , vol.101 , pp. 7-11
    • Ahmann, G.J.1    Jalal, S.M.2    Juneau, A.L.3
  • 32
    • 0034490134 scopus 로고    scopus 로고
    • Chromosome 13 abnormalities in multiple myeloma are mostly monosomy 13
    • Avet-Loiseau H., Daviet A., Saunier S., and Bataille R. Chromosome 13 abnormalities in multiple myeloma are mostly monosomy 13. Br J Haematol 111 (2000) 1116-1117
    • (2000) Br J Haematol , vol.111 , pp. 1116-1117
    • Avet-Loiseau, H.1    Daviet, A.2    Saunier, S.3    Bataille, R.4
  • 33
    • 0034988904 scopus 로고    scopus 로고
    • Deletions of chromosome 13 in multiple myeloma identified by interphase FISH usually denote large deletions of the q-arm or monosomy
    • Fonseca R., Oken M., Harrington D., et al. Deletions of chromosome 13 in multiple myeloma identified by interphase FISH usually denote large deletions of the q-arm or monosomy. Leukemia 15 (2001) 981-986
    • (2001) Leukemia , vol.15 , pp. 981-986
    • Fonseca, R.1    Oken, M.2    Harrington, D.3
  • 34
    • 0037226950 scopus 로고    scopus 로고
    • Delineation of the minimal region of loss at 13q14 in multiple myeloma
    • Elnenaei M.O., Hamoudi R.A., Swansbury J., et al. Delineation of the minimal region of loss at 13q14 in multiple myeloma. Genes Chromosomes Cancer 36 (2003) 99-106
    • (2003) Genes Chromosomes Cancer , vol.36 , pp. 99-106
    • Elnenaei, M.O.1    Hamoudi, R.A.2    Swansbury, J.3
  • 35
    • 0032147210 scopus 로고    scopus 로고
    • Presence of a p53 gene deletion in patients with multiple myeloma predicts for short survival after conventional-dose chemotherapy
    • Drach J., Ackermann J., Fritz E., et al. Presence of a p53 gene deletion in patients with multiple myeloma predicts for short survival after conventional-dose chemotherapy. Blood 92 (1998) 802-809
    • (1998) Blood , vol.92 , pp. 802-809
    • Drach, J.1    Ackermann, J.2    Fritz, E.3
  • 36
    • 0032854511 scopus 로고    scopus 로고
    • P53 deletion is not a frequent event in multiple myeloma
    • Avet-Loiseau H., Li J.Y., Godon C., et al. P53 deletion is not a frequent event in multiple myeloma. Br J Haematol 106 (1999) 717-719
    • (1999) Br J Haematol , vol.106 , pp. 717-719
    • Avet-Loiseau, H.1    Li, J.Y.2    Godon, C.3
  • 38
    • 0038142356 scopus 로고    scopus 로고
    • Clinical and biologic implications of recurrent genomic aberrations in myeloma
    • Fonseca R., Blood E., Rue M., et al. Clinical and biologic implications of recurrent genomic aberrations in myeloma. Blood 101 (2003) 4569-4575
    • (2003) Blood , vol.101 , pp. 4569-4575
    • Fonseca, R.1    Blood, E.2    Rue, M.3
  • 39
    • 9144264192 scopus 로고    scopus 로고
    • High incidence of trisomies 1q, 9q, and 11q in multiple myeloma: results from a comprehensive molecular cytogenetic analysis
    • Liebisch P., Wendl C., Wellmann A., et al. High incidence of trisomies 1q, 9q, and 11q in multiple myeloma: results from a comprehensive molecular cytogenetic analysis. Leukemia 17 (2003) 2535-2537
    • (2003) Leukemia , vol.17 , pp. 2535-2537
    • Liebisch, P.1    Wendl, C.2    Wellmann, A.3
  • 40
    • 27144441760 scopus 로고    scopus 로고
    • Clinical implications of t(11;14)(q13;q32), t(4;14)(p16.3;q32), and -17p13 in myeloma patients treated with high-dose therapy
    • Gertz M.A., Lacy M.Q., Dispenzieri A., et al. Clinical implications of t(11;14)(q13;q32), t(4;14)(p16.3;q32), and -17p13 in myeloma patients treated with high-dose therapy. Blood 106 (2005) 2837-2840
    • (2005) Blood , vol.106 , pp. 2837-2840
    • Gertz, M.A.1    Lacy, M.Q.2    Dispenzieri, A.3
  • 41
    • 0033568514 scopus 로고    scopus 로고
    • 14q32 translocations and monosomy 13 observed in monoclonal gammopathy of undetermined significance delineate a multistep process fo the oncogenesis of multiple myeloma Intergroupe Francophone du Myelome
    • Avet-Loiseau H., Facon T., Daviet A., et al. 14q32 translocations and monosomy 13 observed in monoclonal gammopathy of undetermined significance delineate a multistep process fo the oncogenesis of multiple myeloma Intergroupe Francophone du Myelome. Cancer Res 59 (1999) 4546-4550
    • (1999) Cancer Res , vol.59 , pp. 4546-4550
    • Avet-Loiseau, H.1    Facon, T.2    Daviet, A.3
  • 42
    • 0037092981 scopus 로고    scopus 로고
    • Myeloma and the t(11;14)(q13;q32) represents a uniquely defined biological subset of patients
    • Fonseca R., Harrington D., Oken M., et al. Myeloma and the t(11;14)(q13;q32) represents a uniquely defined biological subset of patients. Blood 99 (2002) 3735-3741
    • (2002) Blood , vol.99 , pp. 3735-3741
    • Fonseca, R.1    Harrington, D.2    Oken, M.3
  • 43
    • 0343355828 scopus 로고    scopus 로고
    • High incidence of translocations t(11;14)(q13;q32) and t(4;14)(p16;q32)
    • Avet-Loiseau H., Li J.Y., Facon T., et al. High incidence of translocations t(11;14)(q13;q32) and t(4;14)(p16;q32). Cancer Res 58 (1998) 5640-5645
    • (1998) Cancer Res , vol.58 , pp. 5640-5645
    • Avet-Loiseau, H.1    Li, J.Y.2    Facon, T.3
  • 44
    • 0032170964 scopus 로고    scopus 로고
    • Multicolour spectral karyotyping identifies new recurring breakpoints and translocations in multiple myeloma
    • Rao P.H., Cigudosa J.C., Ning Y., et al. Multicolour spectral karyotyping identifies new recurring breakpoints and translocations in multiple myeloma. Blood 92 (1998) 1743-1748
    • (1998) Blood , vol.92 , pp. 1743-1748
    • Rao, P.H.1    Cigudosa, J.C.2    Ning, Y.3
  • 45
    • 0035133202 scopus 로고    scopus 로고
    • Multicolour spectral karyotyping identifies new translocations and a recurring pathway for chromosome loss in multiple myeloma
    • Sawyer J.R., Lukacs J.L., Thomas E.L., et al. Multicolour spectral karyotyping identifies new translocations and a recurring pathway for chromosome loss in multiple myeloma. Br J Haematol 112 (2001) 167-174
    • (2001) Br J Haematol , vol.112 , pp. 167-174
    • Sawyer, J.R.1    Lukacs, J.L.2    Thomas, E.L.3
  • 46
    • 22844435493 scopus 로고    scopus 로고
    • Multicolour spectral karyotyping in multiple myeloma
    • Sawyer J.R. Multicolour spectral karyotyping in multiple myeloma. Methods Mol Med 113 (2005) 49-58
    • (2005) Methods Mol Med , vol.113 , pp. 49-58
    • Sawyer, J.R.1
  • 47
    • 0029014965 scopus 로고
    • Jumping genes and the immunoglobulin V gene system
    • Schwartz R.S. Jumping genes and the immunoglobulin V gene system. N Engl J Med 333 (1995) 42-44
    • (1995) N Engl J Med , vol.333 , pp. 42-44
    • Schwartz, R.S.1
  • 48
    • 0031985198 scopus 로고    scopus 로고
    • Multiple myeloma: increasing evidence for a multistep transformation process
    • Hallek M., Leif Bergsagel P., and Anderson K.C. Multiple myeloma: increasing evidence for a multistep transformation process. Blood 91 (1998) 3-21
    • (1998) Blood , vol.91 , pp. 3-21
    • Hallek, M.1    Leif Bergsagel, P.2    Anderson, K.C.3
  • 49
    • 0036512435 scopus 로고    scopus 로고
    • Multiple myeloma:increasing evidence for a multistep transformation process
    • Kuehl W.M., and Bergsagel P.L. Multiple myeloma:increasing evidence for a multistep transformation process. Nat Rev Cancer 2 (2002) 175-187
    • (2002) Nat Rev Cancer , vol.2 , pp. 175-187
    • Kuehl, W.M.1    Bergsagel, P.L.2
  • 50
    • 0034254687 scopus 로고    scopus 로고
    • The role of immunoglobulin translocations in the pathogenesis of B-cell malignancies
    • Willis T.G., and Dyer M.J. The role of immunoglobulin translocations in the pathogenesis of B-cell malignancies. Blood 96 (2000) 808-822
    • (2000) Blood , vol.96 , pp. 808-822
    • Willis, T.G.1    Dyer, M.J.2
  • 51
    • 0035839959 scopus 로고    scopus 로고
    • Mechanisms of chromosomal translocations in B cell lymphomas
    • Küppers R., and Dalla-Favera R. Mechanisms of chromosomal translocations in B cell lymphomas. Oncogene 20 (2001) 5580-5594
    • (2001) Oncogene , vol.20 , pp. 5580-5594
    • Küppers, R.1    Dalla-Favera, R.2
  • 52
  • 53
    • 0030792866 scopus 로고    scopus 로고
    • The Ig heavy chain gene is frequently involved in chromosomal translocations in multiple myeloma and plasma cell leukaemia as detected by in situ hybridization
    • Nishida K., Tamura A., Nakazawa N., et al. The Ig heavy chain gene is frequently involved in chromosomal translocations in multiple myeloma and plasma cell leukaemia as detected by in situ hybridization. Blood 90 (1997) 526-534
    • (1997) Blood , vol.90 , pp. 526-534
    • Nishida, K.1    Tamura, A.2    Nakazawa, N.3
  • 54
    • 0035839841 scopus 로고    scopus 로고
    • Chromosome translocations in multiple myeloma
    • Bergsagel P.L., and Kuehl W.M. Chromosome translocations in multiple myeloma. Oncogene 20 (2001) 5611-5622
    • (2001) Oncogene , vol.20 , pp. 5611-5622
    • Bergsagel, P.L.1    Kuehl, W.M.2
  • 55
    • 0038675193 scopus 로고    scopus 로고
    • Critical roles for immunoglobulin translocations and cyclin D dysregulation in multiple myeloma
    • Bergsagel P., and Kuehl W. Critical roles for immunoglobulin translocations and cyclin D dysregulation in multiple myeloma. Immunol Rev 194 (2003) 96-104
    • (2003) Immunol Rev , vol.194 , pp. 96-104
    • Bergsagel, P.1    Kuehl, W.2
  • 56
    • 8844266049 scopus 로고    scopus 로고
    • Both IGH translocations and chromosome 13q deletions are early events in monoclonal gammopathy of undetermined significance and do not evolve during transition to multiple myeloma
    • Kaufmann H., Ackermann J., Baldia C., et al. Both IGH translocations and chromosome 13q deletions are early events in monoclonal gammopathy of undetermined significance and do not evolve during transition to multiple myeloma. Leukemia 18 (2004) 1879-1882
    • (2004) Leukemia , vol.18 , pp. 1879-1882
    • Kaufmann, H.1    Ackermann, J.2    Baldia, C.3
  • 57
    • 3242777803 scopus 로고    scopus 로고
    • Advances in biology of multiple myeloma: clinical applications
    • Hideshima T., Bergsagel P.L., Kuehl W.M., and Anderson K.C. Advances in biology of multiple myeloma: clinical applications. Blood 104 (2004) 607-618
    • (2004) Blood , vol.104 , pp. 607-618
    • Hideshima, T.1    Bergsagel, P.L.2    Kuehl, W.M.3    Anderson, K.C.4
  • 59
    • 0028033750 scopus 로고
    • A new method for the analysis of plasma cell DNA content in mutiple myeloma samples using a CD38/propidium iodide double staining technique
    • Orfao A., Garcia-Sanz R., Lopez-Berges M.C., et al. A new method for the analysis of plasma cell DNA content in mutiple myeloma samples using a CD38/propidium iodide double staining technique. Cytometry 17 (1994) 332-339
    • (1994) Cytometry , vol.17 , pp. 332-339
    • Orfao, A.1    Garcia-Sanz, R.2    Lopez-Berges, M.C.3
  • 61
    • 0035496928 scopus 로고    scopus 로고
    • Hypodiploidy is a major prognostic factor in multiple myeloma
    • Smadja N.V., Bastard C., Brigaudeau C., Leroux D., and Fruchart C. Hypodiploidy is a major prognostic factor in multiple myeloma. Blood 98 (2001) 2229-2238
    • (2001) Blood , vol.98 , pp. 2229-2238
    • Smadja, N.V.1    Bastard, C.2    Brigaudeau, C.3    Leroux, D.4    Fruchart, C.5
  • 62
    • 0031861960 scopus 로고    scopus 로고
    • Chromosomal analysis in multiple myeloma: cytogenetic evidence of two different diseases
    • Smadja N.V., Fruchart C., Isnard F., et al. Chromosomal analysis in multiple myeloma: cytogenetic evidence of two different diseases. Leukemia 12 (1998) 960-969
    • (1998) Leukemia , vol.12 , pp. 960-969
    • Smadja, N.V.1    Fruchart, C.2    Isnard, F.3
  • 63
    • 10744223381 scopus 로고    scopus 로고
    • Genetics and cytogenetics of multiple myeloma: a workshop report
    • Fonseca R., Barlogie B., Bataille R., et al. Genetics and cytogenetics of multiple myeloma: a workshop report. Cancer Res 64 (2004) 1546-1558
    • (2004) Cancer Res , vol.64 , pp. 1546-1558
    • Fonseca, R.1    Barlogie, B.2    Bataille, R.3
  • 64
    • 0141481984 scopus 로고    scopus 로고
    • The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma
    • Fonseca R., Debes-Marun C., Picken E., et al. The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma. Blood 102 (2003) 2562-2567
    • (2003) Blood , vol.102 , pp. 2562-2567
    • Fonseca, R.1    Debes-Marun, C.2    Picken, E.3
  • 65
    • 0141993685 scopus 로고    scopus 로고
    • Further cytogenetic characterization of multiple myeloma confirms that 14q32 translocations are a very rare event in hyperdiploid patients
    • Smadja N.V., Leroux D., Soulier J., et al. Further cytogenetic characterization of multiple myeloma confirms that 14q32 translocations are a very rare event in hyperdiploid patients. Genes Chromosomes Cancer 38 (2003) 234-239
    • (2003) Genes Chromosomes Cancer , vol.38 , pp. 234-239
    • Smadja, N.V.1    Leroux, D.2    Soulier, J.3
  • 66
    • 9644303290 scopus 로고    scopus 로고
    • Duplication of chromosome arms 9q and 11q: Evidence for a novel, 14q32 translocation-independent pathogenetic pathway in multiple myeloma
    • Liebisch P., Scheck D., Erné S.A., et al. Duplication of chromosome arms 9q and 11q: Evidence for a novel, 14q32 translocation-independent pathogenetic pathway in multiple myeloma. Genes Chromosomes Cancer 42 (2005) 78-81
    • (2005) Genes Chromosomes Cancer , vol.42 , pp. 78-81
    • Liebisch, P.1    Scheck, D.2    Erné, S.A.3
  • 67
    • 0037307238 scopus 로고    scopus 로고
    • Gene expression profiling of human plasma cell differentiation and classification of multiple myeloma based on similarities to distinct stages of late-stage B-cell development
    • Zhan F., Tian E., Bumm K., Smith R., Barlogie B., and Shaughnessy Jr. J. Gene expression profiling of human plasma cell differentiation and classification of multiple myeloma based on similarities to distinct stages of late-stage B-cell development. Blood 101 (2003) 1128-1140
    • (2003) Blood , vol.101 , pp. 1128-1140
    • Zhan, F.1    Tian, E.2    Bumm, K.3    Smith, R.4    Barlogie, B.5    Shaughnessy Jr., J.6
  • 68
    • 0037103205 scopus 로고    scopus 로고
    • Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts
    • Tarte K., De Vos J., Thykjaer T., et al. Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts. Blood 100 (2002) 1113-1122
    • (2002) Blood , vol.100 , pp. 1113-1122
    • Tarte, K.1    De Vos, J.2    Thykjaer, T.3
  • 69
    • 3843111116 scopus 로고    scopus 로고
    • Different mechanisms of cyclin D1 overexpression in multiple myeloma revealed by fluorescence in situ hybridization and quantitative analysis of mRNA levels
    • Specht K., Haralambieva E., Bink K., et al. Different mechanisms of cyclin D1 overexpression in multiple myeloma revealed by fluorescence in situ hybridization and quantitative analysis of mRNA levels. Blood 104 (2004) 1120-1126
    • (2004) Blood , vol.104 , pp. 1120-1126
    • Specht, K.1    Haralambieva, E.2    Bink, K.3
  • 70
    • 0022472775 scopus 로고
    • Biclonal and hypodiploid multiple myeloma
    • Smith L., Barlogie B., and Alexanian R. Biclonal and hypodiploid multiple myeloma. Am. J. Med 80 (1986) 841-843
    • (1986) Am. J. Med , vol.80 , pp. 841-843
    • Smith, L.1    Barlogie, B.2    Alexanian, R.3
  • 71
    • 0028880424 scopus 로고
    • Poor prognosis in multiple myeloma is associated only with partial or complete deletions of chromosome 13 or abnormalities involving 11q and not with other karyotype abnormalities
    • Tricot G., Barlogie B., Jagannath S., et al. Poor prognosis in multiple myeloma is associated only with partial or complete deletions of chromosome 13 or abnormalities involving 11q and not with other karyotype abnormalities. Blood 86 (1995) 4250-4256
    • (1995) Blood , vol.86 , pp. 4250-4256
    • Tricot, G.1    Barlogie, B.2    Jagannath, S.3
  • 72
    • 7144255524 scopus 로고    scopus 로고
    • Prognostic value of cytogenetics in multiple myeloma
    • Seong C., Delasalle K., Hayes K., et al. Prognostic value of cytogenetics in multiple myeloma. Br J Haematol 101 (1998) 189-194
    • (1998) Br J Haematol , vol.101 , pp. 189-194
    • Seong, C.1    Delasalle, K.2    Hayes, K.3
  • 73
    • 18544409610 scopus 로고    scopus 로고
    • Results of high-dose therapy for 1000 patients with multiple myeloma: durable complete remissions and superior survival in the absence of chromosome 13 abnormalities
    • Desikan R., Barlogie B., Sawyer J., et al. Results of high-dose therapy for 1000 patients with multiple myeloma: durable complete remissions and superior survival in the absence of chromosome 13 abnormalities. Blood 95 (2000) 4008-4010
    • (2000) Blood , vol.95 , pp. 4008-4010
    • Desikan, R.1    Barlogie, B.2    Sawyer, J.3
  • 74
    • 18544363372 scopus 로고    scopus 로고
    • Both hypodiploidy and deletion of chromosome 13 independently confer poor prognosis in multiple myeloma
    • Fassas A.B., Spencer T., Sawyer J., et al. Both hypodiploidy and deletion of chromosome 13 independently confer poor prognosis in multiple myeloma. Br J Haematol 118 (2002) 1041-1047
    • (2002) Br J Haematol , vol.118 , pp. 1041-1047
    • Fassas, A.B.1    Spencer, T.2    Sawyer, J.3
  • 75
    • 0038495926 scopus 로고    scopus 로고
    • Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I: interpretation in the context of global gene expression
    • Shaughnessy J., Jacobson J., Sawyer J., et al. Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I: interpretation in the context of global gene expression. Blood 101 (2003) 3849-3856
    • (2003) Blood , vol.101 , pp. 3849-3856
    • Shaughnessy, J.1    Jacobson, J.2    Sawyer, J.3
  • 76
    • 2642617778 scopus 로고    scopus 로고
    • Prognostic value of numerical chromosome aberrations in multiple myeloma: A FISH analysis of 15 different chromosomes
    • Perez-Simon J.A., Garcia-Sanz R., Tabernero M.D., et al. Prognostic value of numerical chromosome aberrations in multiple myeloma: A FISH analysis of 15 different chromosomes. Blood 91 (1998) 3366-3371
    • (1998) Blood , vol.91 , pp. 3366-3371
    • Perez-Simon, J.A.1    Garcia-Sanz, R.2    Tabernero, M.D.3
  • 77
    • 17344395438 scopus 로고    scopus 로고
    • Deletion of 13q14 remains an independent adverse prognostic variable in multiple myeloma despite its frequent detection by interphase fluorescence in situ hybridization
    • Zojer N., Königsberg R., Ackermann J., et al. Deletion of 13q14 remains an independent adverse prognostic variable in multiple myeloma despite its frequent detection by interphase fluorescence in situ hybridization. Blood 95 (2000) 1925-1930
    • (2000) Blood , vol.95 , pp. 1925-1930
    • Zojer, N.1    Königsberg, R.2    Ackermann, J.3
  • 78
    • 0035869257 scopus 로고    scopus 로고
    • Chromosome 13 abnormalities identified by FISH analysis and serum ß-2-microglobulin produce a powerful myeloma staging system for patients receiving high-dose therapy
    • Facon T., Avet-Loiseau H., Guillerm G., et al. Chromosome 13 abnormalities identified by FISH analysis and serum ß-2-microglobulin produce a powerful myeloma staging system for patients receiving high-dose therapy. Blood 97 (2001) 1566-1571
    • (2001) Blood , vol.97 , pp. 1566-1571
    • Facon, T.1    Avet-Loiseau, H.2    Guillerm, G.3
  • 79
    • 0036468246 scopus 로고    scopus 로고
    • Biologic and prognostic significance of interphase FISH detection of chromosome 13 abnormalities (Δ13) in multiple myeloma: an Eastern Cooperative Oncology Group (ECOG) Study
    • Fonseca R., Harrington D., Oken M., et al. Biologic and prognostic significance of interphase FISH detection of chromosome 13 abnormalities (Δ13) in multiple myeloma: an Eastern Cooperative Oncology Group (ECOG) Study. Cancer Res 62 (2002) 715-720
    • (2002) Cancer Res , vol.62 , pp. 715-720
    • Fonseca, R.1    Harrington, D.2    Oken, M.3
  • 80
    • 0037441747 scopus 로고    scopus 로고
    • In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression
    • Keats J.J., Reiman T., Maxwell C.A., et al. In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression. Blood 101 (2003) 1520-1529
    • (2003) Blood , vol.101 , pp. 1520-1529
    • Keats, J.J.1    Reiman, T.2    Maxwell, C.A.3
  • 81
    • 0033763998 scopus 로고    scopus 로고
    • Deletions of chromosome 13q in monoclonal gammopathy of undetermined significance
    • Königsberg R., Ackermann J., Kaufmann H., et al. Deletions of chromosome 13q in monoclonal gammopathy of undetermined significance. Leukemia 14 (2000) 1975-1979
    • (2000) Leukemia , vol.14 , pp. 1975-1979
    • Königsberg, R.1    Ackermann, J.2    Kaufmann, H.3
  • 82
    • 0034663292 scopus 로고    scopus 로고
    • High incidence of chromosome 13 deletion in multiple myeloma detected by multiprobe interphase FISH
    • Shaughnessy J., Tian E., Sawyer J., et al. High incidence of chromosome 13 deletion in multiple myeloma detected by multiprobe interphase FISH. Blood 96 (2000) 1505-1511
    • (2000) Blood , vol.96 , pp. 1505-1511
    • Shaughnessy, J.1    Tian, E.2    Sawyer, J.3
  • 83
    • 33746375088 scopus 로고    scopus 로고
    • Gains on chromosome arm 9q represent a novel and independent marker of adverse prognosis in multiple myeloma patients receiving upfront high-dose chemotherapy and autologous stem cell transplantation
    • abstr; suppl 2
    • Liebisch P., Benner A., Tschajka K., et al. Gains on chromosome arm 9q represent a novel and independent marker of adverse prognosis in multiple myeloma patients receiving upfront high-dose chemotherapy and autologous stem cell transplantation. Haematologica 90 (2005) 88 abstr; suppl 2
    • (2005) Haematologica , vol.90 , pp. 88
    • Liebisch, P.1    Benner, A.2    Tschajka, K.3
  • 84
    • 2542499695 scopus 로고    scopus 로고
    • Deletion of chromosome band 13q14 as detected by fluorescence in situ hybridization is a prognostic factor in patients with multiple myeloma who are receiving allogeneic dose-reduced stem cell transplantation
    • Kröger N., Schilling G., Einsele H., et al. Deletion of chromosome band 13q14 as detected by fluorescence in situ hybridization is a prognostic factor in patients with multiple myeloma who are receiving allogeneic dose-reduced stem cell transplantation. Blood 103 (2004) 4056-4061
    • (2004) Blood , vol.103 , pp. 4056-4061
    • Kröger, N.1    Schilling, G.2    Einsele, H.3
  • 85
    • 0037973279 scopus 로고    scopus 로고
    • A phase 2 study of bortezomib in relapsed, refractory myeloma
    • Richardson P.G., Barlogie B., Berenson J., et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 348 (2003) 2609-2617
    • (2003) N Engl J Med , vol.348 , pp. 2609-2617
    • Richardson, P.G.1    Barlogie, B.2    Berenson, J.3
  • 86
    • 27744568383 scopus 로고    scopus 로고
    • Relationship of patient survival and chromosome anomalies detected in metaphase and/or interphase cells at diagnosis of myeloma
    • Dewald G.W., Therneau T., Larson D., et al. Relationship of patient survival and chromosome anomalies detected in metaphase and/or interphase cells at diagnosis of myeloma. Blood 106 (2005) 3553-3558
    • (2005) Blood , vol.106 , pp. 3553-3558
    • Dewald, G.W.1    Therneau, T.2    Larson, D.3
  • 87
    • 11144219996 scopus 로고    scopus 로고
    • p53 gene deletion detected by fluorescence in situ hybridization is an adverse prognostic factor for patients with multiple myeloma following autologous stem cell transplantation
    • Chang H., Qi C., Yi Q.L., Reece D., and Stewart A.K. p53 gene deletion detected by fluorescence in situ hybridization is an adverse prognostic factor for patients with multiple myeloma following autologous stem cell transplantation. Blood 105 (2005) 358-360
    • (2005) Blood , vol.105 , pp. 358-360
    • Chang, H.1    Qi, C.2    Yi, Q.L.3    Reece, D.4    Stewart, A.K.5
  • 88
    • 0026508061 scopus 로고
    • Mutations of the p53 gene in human myeloma cell lines
    • Mazars G.R., Portier M., Zhang X.G., et al. Mutations of the p53 gene in human myeloma cell lines. Oncogene 7 (1992) 1015-1018
    • (1992) Oncogene , vol.7 , pp. 1015-1018
    • Mazars, G.R.1    Portier, M.2    Zhang, X.G.3
  • 89
    • 0028302085 scopus 로고
    • Inactivation of tumour suppressor genes, p53 and Rb1, in plasma cell dyscrasias
    • Corradini P., Inghirami G., Astolfi M., et al. Inactivation of tumour suppressor genes, p53 and Rb1, in plasma cell dyscrasias. Leukemia 8 (1994) 758-767
    • (1994) Leukemia , vol.8 , pp. 758-767
    • Corradini, P.1    Inghirami, G.2    Astolfi, M.3
  • 90
    • 0027505575 scopus 로고
    • p53 gene mutations in multiple myeloma are associated with advanced forms of malignancy
    • Neri A., Baldini L., Trecca D., Cro L., Polli E., and Maiolo A.T. p53 gene mutations in multiple myeloma are associated with advanced forms of malignancy. Blood 81 (1993) 128-135
    • (1993) Blood , vol.81 , pp. 128-135
    • Neri, A.1    Baldini, L.2    Trecca, D.3    Cro, L.4    Polli, E.5    Maiolo, A.T.6
  • 91
    • 0026780478 scopus 로고
    • Rare occurrence of p53 gene mutations in multiple myeloma
    • Preudhomme C., Facon T., Zandecki M., et al. Rare occurrence of p53 gene mutations in multiple myeloma. Br J Haematol 81 (1992) 440-443
    • (1992) Br J Haematol , vol.81 , pp. 440-443
    • Preudhomme, C.1    Facon, T.2    Zandecki, M.3
  • 92
    • 0032428365 scopus 로고    scopus 로고
    • Absence of p53 deletions in bone marrow plasma cells of patients with monoclonal gammopathy of undetermined significance
    • Ackermann J., Meidlinger P., Zojer N., Gisslinger H., Ludwig H., Huber H., and Drach J. Absence of p53 deletions in bone marrow plasma cells of patients with monoclonal gammopathy of undetermined significance. Br J Haematol 103 (1998) 1161-1163
    • (1998) Br J Haematol , vol.103 , pp. 1161-1163
    • Ackermann, J.1    Meidlinger, P.2    Zojer, N.3    Gisslinger, H.4    Ludwig, H.5    Huber, H.6    Drach, J.7
  • 93
    • 0037443390 scopus 로고    scopus 로고
    • Overall and event-free survival are not improved by the use of myeloablative therapy following intensified chemotherapy in previously untreated patients with multiple myeloma: a prospective randomized phase 3 study
    • Segeren C.M., Sonneveld P., van der Holt B., et al. Overall and event-free survival are not improved by the use of myeloablative therapy following intensified chemotherapy in previously untreated patients with multiple myeloma: a prospective randomized phase 3 study. Blood 101 (2003) 2144-2151
    • (2003) Blood , vol.101 , pp. 2144-2151
    • Segeren, C.M.1    Sonneveld, P.2    van der Holt, B.3
  • 94
    • 29244455863 scopus 로고    scopus 로고
    • Amplification and overexpression of CKS1B at chromosome band 1q21 is associated with reduced levels of p27(Kip1) and an aggressive clinical course in multiple myeloma
    • Shaughnessy J. Amplification and overexpression of CKS1B at chromosome band 1q21 is associated with reduced levels of p27(Kip1) and an aggressive clinical course in multiple myeloma. Haematology 10 Suppl 1 (2005) 117-126
    • (2005) Haematology , vol.10 , Issue.SUPPL. 1 , pp. 117-126
    • Shaughnessy, J.1
  • 95
    • 0031838436 scopus 로고    scopus 로고
    • Multiple myeloma and the translocation t(11;14)(q13;q32) - a report on 13 cases
    • Fonseca R., Witzig T.E., Gertz M.A., et al. Multiple myeloma and the translocation t(11;14)(q13;q32) - a report on 13 cases. Br J Haematol 101 (1998) 296-301
    • (1998) Br J Haematol , vol.101 , pp. 296-301
    • Fonseca, R.1    Witzig, T.E.2    Gertz, M.A.3
  • 96
    • 0036493522 scopus 로고    scopus 로고
    • Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells
    • Zhan F., Hardin J., Kordsmeier B., et al. Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells. Blood 99 (2002) 1745-1757
    • (2002) Blood , vol.99 , pp. 1745-1757
    • Zhan, F.1    Hardin, J.2    Kordsmeier, B.3
  • 97
    • 0036721371 scopus 로고    scopus 로고
    • Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy
    • Moreau P., Facon T., Leleu X., et al. Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy. Blood 100 (2002) 1579-1583
    • (2002) Blood , vol.100 , pp. 1579-1583
    • Moreau, P.1    Facon, T.2    Leleu, X.3
  • 98
    • 0034502263 scopus 로고    scopus 로고
    • The (11;14)(q13;q32) translocation in multiple myeloma A morphologic and immunohistochemical study
    • Hoyer J.D., Hanson C.A., Fonseca R., Greipp P.R., Dewald G.W., and Kurtin P.J. The (11;14)(q13;q32) translocation in multiple myeloma A morphologic and immunohistochemical study. Am J Clin Pathol 113 (2000) 831-837
    • (2000) Am J Clin Pathol , vol.113 , pp. 831-837
    • Hoyer, J.D.1    Hanson, C.A.2    Fonseca, R.3    Greipp, P.R.4    Dewald, G.W.5    Kurtin, P.J.6
  • 99
    • 0042744766 scopus 로고    scopus 로고
    • CD20 is associated with a small mature plasma cell morphology and t(11;14) in multiple myeloma
    • Robillard N., Avet-Loiseau H., Garand R., et al. CD20 is associated with a small mature plasma cell morphology and t(11;14) in multiple myeloma. Blood 102 (2003) 1070-1071
    • (2003) Blood , vol.102 , pp. 1070-1071
    • Robillard, N.1    Avet-Loiseau, H.2    Garand, R.3
  • 100
    • 0037441892 scopus 로고    scopus 로고
    • Translocation t(11;14)(q13;q32) is the hallmark of IgM, IgE, and nonsecretory multiple myeloma variants
    • Avet-Loiseau H., Garand R., Lode L., Harousseau J.-L., and Bataille R. Translocation t(11;14)(q13;q32) is the hallmark of IgM, IgE, and nonsecretory multiple myeloma variants. Blood 101 (2003) 1570-1571
    • (2003) Blood , vol.101 , pp. 1570-1571
    • Avet-Loiseau, H.1    Garand, R.2    Lode, L.3    Harousseau, J.-L.4    Bataille, R.5
  • 101
    • 0042943201 scopus 로고    scopus 로고
    • Cyclin D1 overexpression is a favourable prognostic variable for newly diagnosed multiple myeloma patients treated with high-dose chemotherapy and single or double autologous transplantation
    • Soverini S., Cavo M., Cellini C., et al. Cyclin D1 overexpression is a favourable prognostic variable for newly diagnosed multiple myeloma patients treated with high-dose chemotherapy and single or double autologous transplantation. Blood 102 (2003) 1588-1594
    • (2003) Blood , vol.102 , pp. 1588-1594
    • Soverini, S.1    Cavo, M.2    Cellini, C.3
  • 102
    • 0030842266 scopus 로고    scopus 로고
    • A novel chromosomal translocation t(4;14)(p16.3;q32) in multiple myeloma involves the fibroblast growth-factor receptor 3 gene
    • Richelda R., Ronchetti D., Baldini L., et al. A novel chromosomal translocation t(4;14)(p16.3;q32) in multiple myeloma involves the fibroblast growth-factor receptor 3 gene. Blood 90 (1997) 4062-4070
    • (1997) Blood , vol.90 , pp. 4062-4070
    • Richelda, R.1    Ronchetti, D.2    Baldini, L.3
  • 103
    • 0037441747 scopus 로고    scopus 로고
    • In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression
    • Keats J.J., Reiman T., Maxwell C.A., et al. In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression. Blood 101 (2003) 1520-1529
    • (2003) Blood , vol.101 , pp. 1520-1529
    • Keats, J.J.1    Reiman, T.2    Maxwell, C.A.3
  • 104
    • 0037443417 scopus 로고    scopus 로고
    • A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript
    • Santra M., Zhan F., Tian E., Barlogie B., and Shaughnessy Jr. J. A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript. Blood 101 (2003) 2374-2376
    • (2003) Blood , vol.101 , pp. 2374-2376
    • Santra, M.1    Zhan, F.2    Tian, E.3    Barlogie, B.4    Shaughnessy Jr., J.5


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