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Volumn 104, Issue 4, 2004, Pages 1120-1126

Different mechanisms of cyclin D1 overexpression in multiple myeloma revealed by fluorescence in situ hybridization and quantitative analysis of mRNA levels

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; IMMUNOGLOBULIN HEAVY CHAIN; MESSENGER RNA; TATA BINDING PROTEIN;

EID: 3843111116     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-11-3837     Document Type: Article
Times cited : (102)

References (38)
  • 1
    • 0036512435 scopus 로고    scopus 로고
    • Multiple myeloma: Evolving genetic events and host interactions
    • Kuehl WM, Bergsagel PL. Multiple myeloma: evolving genetic events and host interactions. Nat Rev Cancer. 2002;2:175-187.
    • (2002) Nat Rev Cancer , vol.2 , pp. 175-187
    • Kuehl, W.M.1    Bergsagel, P.L.2
  • 2
    • 0036796603 scopus 로고    scopus 로고
    • Molecular aspects of multiple myeloma
    • Pratt G. Molecular aspects of multiple myeloma. Mol Pathol. 2002;55:273-283.
    • (2002) Mol Pathol , vol.55 , pp. 273-283
    • Pratt, G.1
  • 3
    • 0031201186 scopus 로고    scopus 로고
    • Virtually identical enhancers containing a segment of homology to murine 3′IgH-E(hs1,2) lie downstream of human Ig C alpha 1 and C alpha 2 genes
    • Chen C, Birshtein BK. Virtually identical enhancers containing a segment of homology to murine 3′IgH-E(hs1,2) lie downstream of human Ig C alpha 1 and C alpha 2 genes. J Immunol. 1997;159:1310-1318.
    • (1997) J Immunol , vol.159 , pp. 1310-1318
    • Chen, C.1    Birshtein, B.K.2
  • 4
    • 0030886813 scopus 로고    scopus 로고
    • Enhancer complexes located downstream of both human immunoglobulin Calpha genes
    • Mills FC, Harindranath N, Mitchell M, Max EE. Enhancer complexes located downstream of both human immunoglobulin Calpha genes. J Exp Med. 1997;186:845-858.
    • (1997) J Exp Med , vol.186 , pp. 845-858
    • Mills, F.C.1    Harindranath, N.2    Mitchell, M.3    Max, E.E.4
  • 5
    • 0035839841 scopus 로고    scopus 로고
    • Chromosome translocations in multiple myeloma
    • Bergsagel PL, Kuehl WM. Chromosome translocations in multiple myeloma. Oncogene. 2001;20:5611-5622.
    • (2001) Oncogene , vol.20 , pp. 5611-5622
    • Bergsagel, P.L.1    Kuehl, W.M.2
  • 6
    • 0032170964 scopus 로고    scopus 로고
    • Multicolor spectral karyotyping identifies new recurring breakpoints and translocations in multiple myeloma
    • Rao PH, Cigudosa JC, Ning Y, et al. Multicolor spectral karyotyping identifies new recurring breakpoints and translocations in multiple myeloma. Blood. 1998;92:1743-1748.
    • (1998) Blood , vol.92 , pp. 1743-1748
    • Rao, P.H.1    Cigudosa, J.C.2    Ning, Y.3
  • 7
    • 0032402134 scopus 로고    scopus 로고
    • Identification of new nonrandom translocations in multiple myeloma with multicolor spectral karyotyping
    • Sawyer JR, Lukacs JL, Munshi N, et al. Identification of new nonrandom translocations in multiple myeloma with multicolor spectral karyotyping. Blood. 1998;92:4269-4278.
    • (1998) Blood , vol.92 , pp. 4269-4278
    • Sawyer, J.R.1    Lukacs, J.L.2    Munshi, N.3
  • 8
    • 0030792866 scopus 로고    scopus 로고
    • The Ig heavy chain gene is frequently involved in chromosomal translocations in multiple myeloma and plasma cell leukemia as detected by in situ hybridization
    • Nishida K, Tamura A, Nakazawa N, et al. The Ig heavy chain gene is frequently involved in chromosomal translocations in multiple myeloma and plasma cell leukemia as detected by in situ hybridization. Blood. 1997;90:526-534.
    • (1997) Blood , vol.90 , pp. 526-534
    • Nishida, K.1    Tamura, A.2    Nakazawa, N.3
  • 9
    • 0021792205 scopus 로고
    • The clinical significance of cytogenetic studies in 100 patients with multiple myeloma, plasma cell leukemia, or amyloidosis
    • Dewald GW, Kyle RA, Hicks GA, Greipp PR. The clinical significance of cytogenetic studies in 100 patients with multiple myeloma, plasma cell leukemia, or amyloidosis. Blood. 1985;66:380-390.
    • (1985) Blood , vol.66 , pp. 380-390
    • Dewald, G.W.1    Kyle, R.A.2    Hicks, G.A.3    Greipp, P.R.4
  • 11
    • 0031861960 scopus 로고    scopus 로고
    • Chromosomal analysis in multiple myeloma: Cytogenetic evidence of two different diseases
    • Smadja NV, Fruchart C, Isnard F, et al. Chromosomal analysis in multiple myeloma: cytogenetic evidence of two different diseases. Leukemia. 1998;12:960-969.
    • (1998) Leukemia , vol.12 , pp. 960-969
    • Smadja, N.V.1    Fruchart, C.2    Isnard, F.3
  • 12
    • 0343355828 scopus 로고    scopus 로고
    • High incidence of translocations t(11;14)(q13;q32) and t(4;14)(p16;q32) in patients with plasma cell malignancies
    • Avet-Loiseau H, Li JY, Facon T, et al. High incidence of translocations t(11;14)(q13;q32) and t(4;14)(p16;q32) in patients with plasma cell malignancies. Cancer Res. 1998;58:5640-5645.
    • (1998) Cancer Res , vol.58 , pp. 5640-5645
    • Avet-Loiseau, H.1    Li, J.Y.2    Facon, T.3
  • 13
    • 9444286481 scopus 로고    scopus 로고
    • Direct visualization of dispersed 11q13 chromosomal translocations in mantle cell lymphoma by multicolor DNA fiber fluorescence in situ hybridization
    • Vaandrager JW, Schuuring E, Zwikstra E, et al. Direct visualization of dispersed 11q13 chromosomal translocations in mantle cell lymphoma by multicolor DNA fiber fluorescence in situ hybridization. Blood. 1996;88:1177-1182.
    • (1996) Blood , vol.88 , pp. 1177-1182
    • Vaandrager, J.W.1    Schuuring, E.2    Zwikstra, E.3
  • 14
    • 0031033513 scopus 로고    scopus 로고
    • The t(11; 14) (q13;q32) in multiple myeloma cell line KMS12 has its 11q13 breakpoint 330 kb ceniromeric from the cyclin D1 gene
    • Vaandrager JW, Kluin P, Schuurlng E. The t(11;14) (q13;q32) in multiple myeloma cell line KMS12 has its 11q13 breakpoint 330 kb ceniromeric from the cyclin D1 gene. Blood. 1997;89:349-350.
    • (1997) Blood , vol.89 , pp. 349-350
    • Vaandrager, J.W.1    Kluin, P.2    Schuurlng, E.3
  • 15
    • 0034656068 scopus 로고    scopus 로고
    • Concurrent activation of a novel putative transforming gene, myeov, and cyclin D1 in a subset of multiple myeloma cell lines with t(11;14)(q13; q32)
    • Janssen JW, Vaandrager JW, Heuser T, et al. Concurrent activation of a novel putative transforming gene, myeov, and cyclin D1 in a subset of multiple myeloma cell lines with t(11;14)(q13; q32). Blood. 2000;95:2691-2698.
    • (2000) Blood , vol.95 , pp. 2691-2698
    • Janssen, J.W.1    Vaandrager, J.W.2    Heuser, T.3
  • 16
    • 0036772195 scopus 로고    scopus 로고
    • Detection of three common translocation breakpoints in non-Hodgkin's lymphomas by fluorescence in situ hybridization on routine paraffin-embedded tissue sections
    • Haralambieva E, Kleiverda K, Mason DY, Schuuring E, Kluin PM. Detection of three common translocation breakpoints in non-Hodgkin's lymphomas by fluorescence in situ hybridization on routine paraffin-embedded tissue sections. J Pathol. 2002;198:163-170.
    • (2002) J Pathol , vol.198 , pp. 163-170
    • Haralambieva, E.1    Kleiverda, K.2    Mason, D.Y.3    Schuuring, E.4    Kluin, P.M.5
  • 17
    • 0023125752 scopus 로고
    • Histologic classification and staging of multiple myeloma: A retrospective and prospective study of 674 cases
    • Bartl R, Frisch B, Fateh-Moghadam A, Kettner G, Jaeger K, Sommerfeld W. Histologic classification and staging of multiple myeloma: a retrospective and prospective study of 674 cases. Am J Clin Pathol. 1987;87:342-355.
    • (1987) Am J Clin Pathol , vol.87 , pp. 342-355
    • Bartl, R.1    Frisch, B.2    Fateh-Moghadam, A.3    Kettner, G.4    Jaeger, K.5    Sommerfeld, W.6
  • 18
    • 0037408535 scopus 로고    scopus 로고
    • Analysis of signal transducer and activator of transcription 3 (Stat 3) pathway in multiple myeloma: Stat3 activation and cyclin D1 dysregulation are mutually exclusive events
    • Quintanilla-Martinez L, Kremer M, Specht K, et al. Analysis of signal transducer and activator of transcription 3 (Stat 3) pathway in multiple myeloma: Stat3 activation and cyclin D1 dysregulation are mutually exclusive events. Am J Pathol. 2003;162:1449-1461.
    • (2003) Am J Pathol , vol.162 , pp. 1449-1461
    • Quintanilla-Martinez, L.1    Kremer, M.2    Specht, K.3
  • 19
    • 0036718690 scopus 로고    scopus 로고
    • Identification of cyclin D1 mRNA overexpression in B-cell neoplasias by real-time reverse transcription-PCR of microdissected paraffin sections
    • Specht K, Kremer M, Muller U, et al. Identification of cyclin D1 mRNA overexpression in B-cell neoplasias by real-time reverse transcription-PCR of microdissected paraffin sections. Clin Cancer Res. 2002;8:2902-2911.
    • (2002) Clin Cancer Res , vol.8 , pp. 2902-2911
    • Specht, K.1    Kremer, M.2    Muller, U.3
  • 20
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanatephenol-chloroform extraction
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanatephenol-chloroform extraction. Anal Biochem. 1987;162:156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 21
    • 0030058567 scopus 로고    scopus 로고
    • Detection of 11q13 rearrangements in hematologic neoplasias by double-color fluorescence in situ hybridization
    • Coignet LJ, Schuuring E, Kibbelaar RE, et al. Detection of 11q13 rearrangements in hematologic neoplasias by double-color fluorescence in situ hybridization. Blood. 1996;87:1512-1519.
    • (1996) Blood , vol.87 , pp. 1512-1519
    • Coignet, L.J.1    Schuuring, E.2    Kibbelaar, R.E.3
  • 22
    • 0025282239 scopus 로고
    • Organization of variable region segments of the human immunoglobulin heavy chain: Duplication of the D5 cluster within the locus and interchromosomal translocation of variable region segments
    • Matsuda F, Shin EK, Hirabayashi Y, et al. Organization of variable region segments of the human immunoglobulin heavy chain: duplication of the D5 cluster within the locus and interchromosomal translocation of variable region segments, EMBO J. 1990;9:2501-2506.
    • (1990) EMBO J , vol.9 , pp. 2501-2506
    • Matsuda, F.1    Shin, E.K.2    Hirabayashi, Y.3
  • 23
    • 0032532328 scopus 로고    scopus 로고
    • DNA fiber fluorescence in situ hybridization analysis of immunoglobulin class switching in B-cell neoplasia: Aberrant CH gene rearrangements in follicle center-cell lymphoma
    • Vaandrager JW, Schuuring E, Kluin-Nelemans HC, Dyer MJ, Raap AK, Kluin PM. DNA fiber fluorescence in situ hybridization analysis of immunoglobulin class switching in B-cell neoplasia: aberrant CH gene rearrangements in follicle center-cell lymphoma. Blood. 1998;92:2871-2878.
    • (1998) Blood , vol.92 , pp. 2871-2878
    • Vaandrager, J.W.1    Schuuring, E.2    Kluin-Nelemans, H.C.3    Dyer, M.J.4    Raap, A.K.5    Kluin, P.M.6
  • 24
    • 0030667493 scopus 로고    scopus 로고
    • Visualization of mono-allelic chromosomal aberrations 3′ and 5′ of the cyclin D1 gene in mantle cell lymphoma using DNA fiber fluorescence in situ hybridization
    • de Boer CJ, Vaandrager JW, van Krieken JH, Holmes Z, Kluin PM, Schuuring E. Visualization of mono-allelic chromosomal aberrations 3′ and 5′ of the cyclin D1 gene in mantle cell lymphoma using DNA fiber fluorescence in situ hybridization. Oncogene. 1997;15:1599-1603.
    • (1997) Oncogene , vol.15 , pp. 1599-1603
    • De Boer, C.J.1    Vaandrager, J.W.2    Van Krieken, J.H.3    Holmes, Z.4    Kluin, P.M.5    Schuuring, E.6
  • 25
    • 0032733591 scopus 로고    scopus 로고
    • 20q13.2 amplification in intraductal hyperplasia adjacent to in situ and invasive ductal carcinoma of the breast
    • Werner M, Mattis A, Aubele M, et al. 20q13.2 amplification in intraductal hyperplasia adjacent to in situ and invasive ductal carcinoma of the breast. Virchows Arch. 1999;435:469-472.
    • (1999) Virchows Arch , vol.435 , pp. 469-472
    • Werner, M.1    Mattis, A.2    Aubele, M.3
  • 26
    • 0023949872 scopus 로고
    • In situ hybridization as a tool to study numerical chromosome aberrations in solid bladder tumors
    • Hopman AH, Ramaekers FC, Raap AK, et al. In situ hybridization as a tool to study numerical chromosome aberrations in solid bladder tumors. Histochemistry. 1988;89:307-316.
    • (1988) Histochemistry , vol.89 , pp. 307-316
    • Hopman, A.H.1    Ramaekers, F.C.2    Raap, A.K.3
  • 27
    • 0042943201 scopus 로고    scopus 로고
    • Cyclin D1 overexpression is a favorable prognostic variable for newly diagnosed multiple myeloma patients treated with high-dose chemotherapy and single or double autologous transplantation
    • Soverini S, Cavo M, Cellini C, et al. Cyclin D1 overexpression is a favorable prognostic variable for newly diagnosed multiple myeloma patients treated with high-dose chemotherapy and single or double autologous transplantation. Blood. 2003;102:1588-1594.
    • (2003) Blood , vol.102 , pp. 1588-1594
    • Soverini, S.1    Cavo, M.2    Cellini, C.3
  • 28
    • 0038466245 scopus 로고    scopus 로고
    • Real-time quantitative RT-PCR of cyclin D1 mRNA in mantle cell lymphoma: Comparison with FISH and immunohistochemistry
    • Hui P, Howe JG, Crouch J, et al. Real-time quantitative RT-PCR of cyclin D1 mRNA in mantle cell lymphoma: comparison with FISH and immunohistochemistry. Leuk Lymphoma. 2003;44:1385-1394.
    • (2003) Leuk Lymphoma , vol.44 , pp. 1385-1394
    • Hui, P.1    Howe, J.G.2    Crouch, J.3
  • 29
    • 0035711310 scopus 로고    scopus 로고
    • Frequency and prognostic relevance of cyclin D1 dysregulation in multiple myeloma
    • Rasmussen T, Knudsen LM, Johnsen HE. Frequency and prognostic relevance of cyclin D1 dysregulation in multiple myeloma. Eur J Haematol. 2001;67:296-301.
    • (2001) Eur J Haematol , vol.67 , pp. 296-301
    • Rasmussen, T.1    Knudsen, L.M.2    Johnsen, H.E.3
  • 30
    • 0033838792 scopus 로고    scopus 로고
    • Immunohistochemical analysis of cyclin D1 shows deregulated expression in multiple myeloma with the t(11;14)
    • Pruned G, Fabris S, Baldini L, et al. Immunohistochemical analysis of cyclin D1 shows deregulated expression in multiple myeloma with the t(11;14). Am J Pathol. 2000;156:1505-1513.
    • (2000) Am J Pathol , vol.156 , pp. 1505-1513
    • Pruned, G.1    Fabris, S.2    Baldini, L.3
  • 31
    • 8944237001 scopus 로고    scopus 로고
    • Incidence of chromosome numerical changes in multiple myeloma: Fluorescence in situ hybridization analysis using 15 chromosome-specific probes
    • Tabernero D, San Miguel JF, Garcia-Sanz M, et al. Incidence of chromosome numerical changes in multiple myeloma: fluorescence in situ hybridization analysis using 15 chromosome-specific probes. Am J Pathol. 1996;149:153-161.
    • (1996) Am J Pathol , vol.149 , pp. 153-161
    • Tabernero, D.1    San Miguel, J.F.2    Garcia-Sanz, M.3
  • 32
    • 2642617778 scopus 로고    scopus 로고
    • Prognostic value of numerical chromosome aberrations in multiple myeloma: A FISH analysis of 15 different chromosomes
    • Perez-Simon JA, Garcia-Sanz R, Tabernero MD, et al. Prognostic value of numerical chromosome aberrations in multiple myeloma: a FISH analysis of 15 different chromosomes. Blood. 1998;91:3366-3371.
    • (1998) Blood , vol.91 , pp. 3366-3371
    • Perez-Simon, J.A.1    Garcia-Sanz, R.2    Tabernero, M.D.3
  • 33
    • 0037353820 scopus 로고    scopus 로고
    • A pooled analysis of karyotypic patterns, breakpoints and imbalances in 783 cytogenetically abnormal multiple myelomas reveals frequently involved chromosome segments as well as significant age-and sex-related differences
    • Nilsson T, Hoglund M, Lenhoff S, et al. A pooled analysis of karyotypic patterns, breakpoints and imbalances in 783 cytogenetically abnormal multiple myelomas reveals frequently involved chromosome segments as well as significant age-and sex-related differences. Br J Haematol. 2003;120:960-969.
    • (2003) Br J Haematol , vol.120 , pp. 960-969
    • Nilsson, T.1    Hoglund, M.2    Lenhoff, S.3
  • 34
    • 0029043876 scopus 로고
    • The involvement of the chromosome 11q13 region in human malignancies: Cyclin D1 and EMS1 are two new candidate oncogenes - A review
    • Schuuring E. The involvement of the chromosome 11q13 region in human malignancies: cyclin D1 and EMS1 are two new candidate oncogenes - a review. Gene. 1995;159:83-96.
    • (1995) Gene , vol.159 , pp. 83-96
    • Schuuring, E.1
  • 35
    • 0032971585 scopus 로고    scopus 로고
    • Insertion of excised IgH switch sequences causes overexpression of cyclin D1 in a myeloma tumor cell
    • Gabrea A, Bergsagel PL, Chesi M, Shou Y, Kuehl WM. Insertion of excised IgH switch sequences causes overexpression of cyclin D1 in a myeloma tumor cell. Mol Cell. 1999;3:119-123.
    • (1999) Mol Cell , vol.3 , pp. 119-123
    • Gabrea, A.1    Bergsagel, P.L.2    Chesi, M.3    Shou, Y.4    Kuehl, W.M.5
  • 36
    • 0037092981 scopus 로고    scopus 로고
    • Myeloma and the t(11;14)(q13;q32); evidence for a biologically defined unique subset of patients
    • Fonseca R, Blood EA, Oken MM, et al. Myeloma and the t(11;14)(q13;q32); evidence for a biologically defined unique subset of patients. Blood. 2002;99:3735-3741.
    • (2002) Blood , vol.99 , pp. 3735-3741
    • Fonseca, R.1    Blood, E.A.2    Oken, M.M.3
  • 37
    • 0141481984 scopus 로고    scopus 로고
    • The recurrent IgH translocations are highly associated with non-hyperdiploid variant multiple myeloma
    • Fonseca R, Debes-Marun CS, Picken EB, et al. The recurrent IgH translocations are highly associated with non-hyperdiploid variant multiple myeloma. Blood. 2003;102:2562-2567.
    • (2003) Blood , vol.102 , pp. 2562-2567
    • Fonseca, R.1    Debes-Marun, C.S.2    Picken, E.B.3
  • 38
    • 0036721371 scopus 로고    scopus 로고
    • Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy
    • Moreau P, Facon T, Leleu X, et al. Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy. Blood. 2002;100:1579-1583.
    • (2002) Blood , vol.100 , pp. 1579-1583
    • Moreau, P.1    Facon, T.2    Leleu, X.3


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