Expression and characterization of constitutively active human caspase-14

Biochemical and Biophysical Research Communications

Volumn 347, Issue 4, 2006, Pages 941-948

  Park, Kyewhan ^a   Kuechle, Melanie K ^a   Choe, Youngchool ^b   Craik, Charles S ^b   Lawrence, Owen T ^a   Presland, Richard B ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Caspase; Caspase 14; Endoproteinase; Keratinocyte; Recombinant protein

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 14; CELL EXTRACT; TETRAPEPTIDE;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CULTURE; CELL DIFFERENTIATION; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; HUMAN; HUMAN CELL; KERATINOCYTE; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN ENGINEERING; PROTEIN EXPRESSION;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; CASPASE 14; CASPASES; CELL DIFFERENTIATION; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; COS CELLS; ESCHERICHIA COLI; HUMANS; KERATINOCYTES; OLIGOPEPTIDES; RATS; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI; MAMMALIA;

EID: 33746355249     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.06.156     Document Type: Article

References (40)

1. Thornberry N.A., and Lazebnik Y. Caspases: enemies within. Science 281 (1998) 1312-1316
2. Earnshaw W.C., Martins L.M., and Kaufmann S.H. Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu. Rev. Biochem. 68 (1999) 383-424
3. Garcia-Calvo M., Peterson E.P., Rasper D.M., Vaillancourt J.P., Zamboni R., Nicholson D.W., and Thornberry N.A. Purification and catalytic properties of human caspase family members. Cell Death Differ. 6 (1999) 362-369
4. Denault J.B., and Salvesen G.S. Caspases: keys in the ignition of cell death. Chem. Rev. 102 (2002) 4489-4500
5. Eckhart L., Ballaun C., Uthman A., Kittel C., Stichenwirth M., Buchberger M., Fischer H., Sipos W., and Tschachler E. Identification and characterization of a novel mammalian caspase with proapoptotic activity. J. Biol. Chem. 280 (2005) 35077-35080
6. Metkar S.S., Wang B., Ebbs M.L., Kim J.H., Lee Y.J., Raja S.M., and Froelich C.J. Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis. J. Cell Biol. 160 (2003) 875-885
7. Bizat N., Hermel J.M., Humbert S., Jacquard C., Creminon C., Escartin C., Saudou F., Krajewski S., Hantraye P., and Brouillet E. In vivo calpain/caspase cross-talk during 3-nitropropionic acid-induced striatal degeneration: implication of a calpain-mediated cleavage of active caspase-3. J. Biol. Chem. 278 (2003) 43245-43253
8. Kuechle M.K., Predd H.M., Fleckman P., Dale B.A., and Presland R.B. Caspase-14, a keratinocyte specific caspase: mRNA splice variants and expression pattern in embryonic and adult mouse. Cell Death Differ. 8 (2001) 868-870
9. Lippens S., VandenBroecke C., Van Damme E., Tschachler E., Vandenabeele P., and Declercq W. Caspase-14 is expressed in the epidermis, the choroid plexus, the retinal pigment epithelium and thymic Hassall's bodies. Cell Death Differ. 10 (2003) 257-259
10. Hathaway T.R., and Kuechle M.K. Apoptosis and cutaneous biology. Adv. Dermatol. 18 (2002) 287-311
11. Lippens S., Kockx M., Knaapen M., Mortier L., Polakowska R., Verheyen A., Garmyn M., Zwijsen A., Formstecher P., Huylebroeck D., Vandenabeele P., and Declercq W. Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing. Cell Death Differ. 7 (2000) 1218-1224
12. Alibardi L., Dockal M., Reinisch C., Tschachler E., and Eckhart L. Ultrastructural localization of caspase-14 in human epidermis. J. Histochem. Cytochem. 52 (2004) 1561-1574
13. Krajewska M., Rosenthal R.E., Mikolajczyk J., Stennicke H.R., Wiesenthal T., Mai J., Naito M., Salvesen G.S., Reed J.C., Fiskum G., and Krajewski S. Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation. Exp. Neurol. 189 (2004) 261-279
14. Kam D.W., Charles A.K., and Dharmarajan A.M. Caspase-14 expression in the human placenta. Reprod. Biomed. Online 11 (2005) 236-243
15. Ahmad M., Srinivasula S.M., Hegde R., Mukattash R., Fernandes-Alnemri T., and Alnemri E.S. Identification and characterization of murine caspase-14, a new member of the caspase family. Cancer Res. 58 (1998) 5201-5205
16. Mikolajczyk J., Scott F.L., Krajewski S., Sutherlin D.P., and Salvesen G.S. Activation and substrate specificity of caspase-14. Biochemistry 43 (2004) 10560-10569
17. Van de Craen M., Van Loo G., Pype S., Van Criekinge W., Van den brande I., Molemans F., Fiers W., Declercq W., and Vandenabeele P. Identification of a new caspase homologue: caspase-14. Cell Death Differ. 5 (1998) 838-846
18. Chien A.J., Presland R.B., and Kuechle M.K. Processing of native caspase-14 occurs at an atypical cleavage site in normal epidermal differentiation. Biochem. Biophys. Res. Commun. 296 (2002) 911-917
19. Srinivasula S.M., Ahmad M., MacFarlane M., Luo Z., Huang Z., Fernandes-Alnemri T., and Alnemri E.S. Generation of constitutively active recombinant caspases-3 and -6 by rearrangement of their subunits. J. Biol. Chem. 273 (1998) 10107-10111
20. Presland R.B., Tomic-Canic M., Lewis S.P., and Dale B.A. Regulation of human profilaggrin promoter activity in cultured epithelial cells by retinoic acid and glucocorticoids. J. Dermatol. Sci. 27 (2001) 192-205
21. Presland R.B., Bassuk J.A., Kimball J.R., and Dale B.A. Characterization of two distinct calcium-binding sites in the amino-terminus of human profilaggrin. J. Invest. Dermatol. 104 (1995) 218-223
22. Garcia-Calvo M., Peterson E.P., Leiting B., Ruel R., Nicholson D.W., and Thornberry N.A. Inhibition of human caspases by peptide-based and macromolecular inhibitors. J. Biol. Chem. 273 (1998) 32608-32613
23. Choe Y., Leonetti F., Greenbaum D.C., Lecaille F., Bogyo M., Bromme D., Ellman J.A., and Craik C.S. Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities. J. Biol. Chem. 281 (2006) 12824-12832
24. Harris J.L., Backes B.J., Leonetti F., Mahrus S., Ellman J.A., and Craik C.S. Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries. Proc. Natl. Acad. Sci. USA 97 (2000) 7754-7759
25. Haydock P.V., Blomquist C., Brumbaugh S., Dale B.A., Holbrook K.A., and Fleckman P. Antisense profilaggrin RNA delays and decreases profilaggrin expression and alters in vitro differentiation of rat epidermal keratinocytes. J. Invest. Dermatol. 101 (1993) 118-126
26. Presland R.B., Kuechle M.K., Lewis S.P., Fleckman P., and Dale B.A. Regulated expression of human filaggrin in keratinocytes results in cytoskeletal disruption, loss of cell-cell adhesion, and cell cycle arrest. Exp. Cell Res. 270 (2001) 199-213
27. Kuechle M.K., Thulin C.D., Presland R.B., and Dale B.A. Profilaggrin requires both linker and filaggrin peptide sequences to form granules: implications for profilaggrin processing in vivo. J. Invest. Dermatol. 112 (1999) 843-852
28. Dusek R.L., Getsios S., Chen F., Park J.K., Amargo E.V., Cryns V.L., and Green K.J. The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes. J. Biol. Chem. 281 (2005) 3614-3624
29. Byun Y., Chen F., Chang R., Trivedi M., Green K.J., and Cryns V.L. Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis. Cell Death Differ. 8 (2001) 443-450
30. Araya R., Takahashi R., and Nomura Y. Yeast two-hybrid screening using constitutive-active caspase-7 as bait in the identification of PA28gamma as an effector caspase substrate. Cell Death Differ. 9 (2002) 322-328
31. Backes B.J., Harris J.L., Leonetti F., Craik C.S., and Ellman J.A. Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin. Nat. Biotechnol. 18 (2000) 187-193
32. Eckhart L., Declercq W., Ban J., Rendl M., Lengauer B., Mayer C., Lippens S., Vandenabeele P., and Tschachler E. Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation. J. Invest. Dermatol. 115 (2000) 1148-1151
33. Fischer H., Rossiter H., Ghannadan M., Jaeger K., Barresi C., Declercq W., Tschachler E., and Eckhart L. Caspase-14 but not caspase-3 is processed during the development of fetal mouse epidermis. Differentiation 73 (2005) 406-413
34. Rozman-Pungercar J., Kopitar-Jerala N., Bogyo M., Turk D., Vasiljeva O., Stefe I., Vandenabeele P., Bromme D., Puizdar V., Fonovic M., Trstenjak-Prebanda M., Dolenc I., Turk V., and Turk B. Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. Cell Death Differ. 10 (2003) 881-888
35. Fischer H., Stichenwirth M., Dockal M., Ghannadan M., Buchberger M., Bach J., Kapetanopoulos A., Declercq W., Tschachler E., and Eckhart L. Stratum corneum-derived caspase-14 is catalytically active. FEBS Lett. 577 (2004) 446-450
36. Aho S. Plakin proteins are coordinately cleaved during apoptosis but preferentially through the action of different caspases. Exp. Dermatol. 13 (2004) 700-707
37. Kalinin A.E., Aho M., Uitto J., and Aho S. Breaking the connection: caspase 6 disconnects intermediate filament-binding domain of periplakin from its actin-binding N-terminal region. J. Invest. Dermatol. 124 (2005) 46-55
38. Oshima R.G. Apoptosis and keratin intermediate filaments. Cell Death Differ. 9 (2002) 486-492
39. Korfali N., Ruchaud S., Loegering D., Bernard D., Dingwall C., Kaufmann S.H., and Earnshaw W.C. Caspase-7 gene disruption reveals an involvement of the enzyme during the early stages of apoptosis. J. Biol. Chem. 279 (2004) 1030-1039
40. Wu K.C., Bryan J.T., Morasso M.I., Jang S.I., Lee J.H., Yang J.M., Marekov L.N., Parry D.A., and Steinert P.M. Coiled-coil trigger motifs in the 1B and 2B rod domain segments are required for the stability of keratin intermediate filaments. Mol. Biol. Cell 11 (2000) 3539-3558