Adenovirus mediated transduction of the human DNA polymerase eta cDNA

DNA Repair

Volumn 5, Issue 8, 2006, Pages 925-934

  Lima Bessa, Keronninn Moreno ^a   Chiganças, Vanessa ^b   Stary, Anne ^b   Kannouche, Patricia ^b   Sarasin, Alain ^b   Armelini, Melissa Gava ^a   de Fátima Jacysyn, Jacqueline ^a   Amarante Mendes, Gustavo P ^a   Cordeiro Stone, Marila ^c   Cleaver, James E ^d   Menck, Carlos Frederico Martins ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

DNA polymerase eta; DNA repair; Recombinant adenovirus; Ultraviolet light; Xeroderma pigmentosum

Indexed keywords

ADENOVIRUS VECTOR; COMPLEMENTARY DNA; DNA DIRECTED DNA POLYMERASE ETA; DNA POLYMERASE; ENHANCED GREEN FLUORESCENT PROTEIN; UNCLASSIFIED DRUG;

ADENOVIRUS; APOPTOSIS; ARTICLE; CELL CYCLE S PHASE; CELL SURVIVAL; CONTROLLED STUDY; DNA STRAND; DNA SYNTHESIS; EXCISION REPAIR; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; ULTRAVIOLET RADIATION; VIRUS RECOMBINANT; WESTERN BLOTTING; XERODERMA PIGMENTOSUM;

ADENOVIRIDAE; BLOTTING, WESTERN; CELLS, CULTURED; DNA REPAIR; DNA REPLICATION; DNA, COMPLEMENTARY; DNA-DIRECTED DNA POLYMERASE; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; TRANSDUCTION, GENETIC; ULTRAVIOLET RAYS; XERODERMA PIGMENTOSUM;

ADENOVIRIDAE; XERODERMA PIGMENTOSUM;

EID: 33746342482     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2006.05.037     Document Type: Article

References (42)

1. Eisen J.A., and Hanawalt P.C. A phylogenomic study of repair genes, proteins, and processes. Mutat. Res. 435 (1999) 171-213
2. Magnaldo T., and Sarasin A. Xeroderma Pigmentosum: from symptoms and genetics to gene-based skin therapy. Cells Tissues Organs 177 (2004) 189-198
3. Costa R.M., Chiganças V., Galhardo R.S., Carvalho H., and Menck C.F. The eukaryotic nucleotide excision repair pathway. Biochimie 85 (2003) 1083-1099
4. Kannouche P., and Stary A. Xeroderma pigmentosum variant and error-prone DNA polymerases. Biochimie 85 (2003) 1123-1132
5. Cleaver J.E. Xeroderma pigmentosum: variants with normal DNA repair and normal sensitivity to ultraviolet light. J. Invest. Dermatol. 58 (1972) 124-128
6. Lehmann A.R., Kirk-Bell S., Arlet C.F., Patterson M.C., Lohman P.H.M., de Weerd-Kastelein E.A., and Bootsma D. Xeroderma pigmentosum cells with normal levels of excision repair have defect in DNA synthesis after UV-irradiation. Proc. Natl. Acad. Sci. U.S.A. 72 (1975) 219-223
7. Masutani C., Kusumoto R., Yamada A., Dohmae N., Yokoi M., Yuasa M., Araki M., Iwai S., Takio K., and Hanaoka F. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η. Nature 399 (1999) 700-704
8. Johnson R.E., Kondratick C.M., Prakash S., and Prakash L. hRAD30 mutations in the variant form of xeroderma pigmentosum. Science 285 (1999) 263-265
9. Plosky B.S., and Woodgate R. Switching from high-fidelity replicases to low-fidelity lesion-bypass polymerases. Curr. Opin. Genet. Dev. 14 (2004) 113-119
10. Friedberg E.C., Lehmann A.R., and Fuchs R.P.P. Trading places: how do DNA polymerases switch during translesion DNA synthesis?. Mol. Cell 18 (2005) 499-505
11. Ohmori H., Friedberg E.C., Fuchs R.P., Goodman M.F., Hanaoka F., Hinkle D., Kunkel T.A., Lawrence C.W., Livneh Z., Nohmi T., Prakash L., Prakash S., Todo T., Walker G.C., Wang Z., and Woodgate R. The Y-family of DNA polymerases. Mol. Cell 8 (2001) 7-8
12. Lehmann A.R. Replication of damaged DNA by translesion synthesis in human cells. FEBS Lett. 579 (2005) 873-876
13. Maher V.M., Ouellette L.M., Curren R.D., and McCormick J.J. Frequency of ultraviolet light-induced mutations is higher in xeroderma pigmentosum variant cells than in normal human cells. Nature 261 (1976) 593-595
14. Masutani C., Kusumoto R., Iwai S., and Hanaoka F. Mechanisms of accurate translesion synthesis by human DNA polymerase η. EMBO J. 19 (2000) 3100-3109
15. Kannouche P., Broughton B.C., Volker M., Hanaoka F., Mullenders L.H., and Lehmann A.R. Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells. Genes Dev. 15 (2001) 158-172
16. Trincao J., Johnson R.E., Escalante C.R., Prakash S., Prakash L., and Aggarwal A.K. Structure of the catalytic core of S. cerevisiae DNA polymerase eta: implications for translesion DNA synthesis. Mol. Cell 8 (2001) 417-426
17. Stary A., Kannouche P., Lehmann A.R., and Sarasin A. Role of DNA polymerase η in the UV mutation spectrum in human cells. J. Biol. Chem. 278 (2003) 18767-18775
18. Choi J.H., and Pfeifer G.P. The role of DNA polymerase η in UV mutational spectra. DNA Rep. 4 (2005) 211-220
19. Marchetto M.C., Muotri A.R., Magalhães G.S., Ventura A.M., and Menck C.F. The EGFP recombinant adenovirus: an example of efficient gene delivery and expression in human cells. Virus Rev. Res. 6 (2001) 23-33
20. Lusky M. Good manufacturing practice production of adenoviral vectors for clinical trials. Hum. Gene Ther. 16 (2005) 281-291
21. Graham F.L., and Prevec L. Methods for construction of adenovirus vectors. Mol. Biotechnol. 3 (1995) 207-220
22. Mittereder N., March K.L., and Trapnell B.C. Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy. J. Virol. 70 (1996) 7498-7509
23. Maher V.M., Ouellette L.M., Curren R.D., and McCormick J.J. Caffeine enhancement of the cytotoxic and mutagenic effect of ultraviolet irradiation in a xeroderma pigmentosum variant strain of human cells. Biochem. Biophys. Res. Commun. 71 (1976) 228-234
24. Cleaver J.E., Bartholomew J., Char S., Crowley E., Feeney L., and Limoli C.L. Polymerase η and p53 jointly regulate cell survival, apoptosis and Mre11 recombination during S phase checkpoint arrest after UV-irradiation. DNA Rep. 3 (2002) 1-17
25. Laposa R.R., Feeney L., and Cleaver J.E. Recapitulation of the cellular xeroderma pigmentosum-variant phenotypes using short interfering RNA for DNA polymerase H. Cancer Res. 63 (2003) 3909-3912
26. Tissier A., Kannouche P., Reck M.P., Lehmann A.R., Fuchs R.P., and Cordonnier A. Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl protein. DNA Rep. 3 (2004) 1503-1514
27. Kaufmann W.K., Heffernan T.P., Beaulieu L.M., Doherty S., Frank A.R., Zhou Y., Bryant M.F., Zhou T., Luche D.D., Nikolaishvili-Feinberg N., Simpson D.A., and Cordeiro-Stone M. Caffeine and human DNA metabolism: the magic and the mystery. Mutat. Res. 532 (2003) 85-102
28. Cortez D. Caffeine inhibits checkpoint responses without inhibiting the ataxia-telangiectasia-mutated (ATM) and ATM- and Rad3-related (ATR) protein kinases. J. Biol. Chem. 278 (2003) 37139-37145
29. Sarkaria J.N., Busby E.C., Tibbetts R.S., Roos P., Taya Y., Karnitz L.M., and Abraham R.T. Inhibition of ATM and ATR kinase activities by the radiosensitizing agent caffeine. Cancer Res. 59 (1999) 4375-4382
30. Cordeiro-Stone M., Frank A., Bryant M., Oguejiofor I., Hatch S.B., McDaniel L.D., and Kaufmann W.K. DNA damage responses protect xeroderma pigmentosum variant from UVC-induced clastogenesis. Carcinogenesis 23 (2002) 959-965
31. Heffernan T.P., Simpson D.A., Frank A.R., Heinloth A.N., Paules R.S., Cordeiro-Stone M., and Kaufmann W.K. An ATR- and Chk1-ependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage. Mol. Cell. Biol. 22 (2002) 8552-8561
32. King N.M., Nikolaishvili-Feinberg N., Bryant M.F., Luche D.D., Heffernan T.P., Simpson D.A., Hanaoka F., Kaufmann W.K., and Cordeiro-Stone M. Overproduction of DNA polymerase eta does not raise the spontaneous mutation rate in diploid human fibroblasts. DNA Rep. 4 (2005) 714-724
33. Muotri A.R., Marchetto M.C., Zerbini L.F.C., Libermann T.A., Ventura A.M., Sarasin A., and Menck C.F. Complementation of the DNA repair deficiency in human xeroderma pigmentosum group A and C cells by recombinant adenovirus-mediated gene transfer. Hum. Gene Ther. 13 (2002) 1833-1844
34. Armelini M.G., Muotri A.R., Marchetto M.C., Lima-Bessa K.M., Sarasin A., and Menck C.F. Restoring DNA repair capacity of cells from three distinct diseases by XPD gene-recombinant adenovirus. Cancer Gene Ther. 12 (2005) 389-396
35. Marchetto M.C., Muotri A.R., Burns D.K., Friedberg E.C., and Menck C.F. Gene transduction in skin cells: preventing cancer in xeroderma pigmentosum mice. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 17759-17764
36. Masutani C., Araki M., Yamada A., Kusumoto R., Nogimori T., Maekawa T., Iwai S., and Hanaoka F. Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity. EMBO J. 18 (1999) 3491-3501
37. Johnson R.E., Haracska L., Prakash S., and Prakash L. Role of DNA polymerase eta in the bypass of a (6-4) TT photoproduct. Mol. Cell. Biol. 21 (2001) 3558-3563
38. Nikolaishvili-Feinberg N., and Cordeiro-Stone M. Bypass replication in vitro of UV-induced photoproducts blocking leading or lagging strand synthesis. Biochemistry 40 (2001) 15215-15223
39. Yao J., Dixon K., and Carty M.P. A single (6-4) photoproduct inhibits plasmid DNA replication in xeroderma pigmentosum variant cell extracts. Environ. Mol. Mutagen. 38 (2001) 19-29
40. Chiganças V., Sarasin A., and Menck C.F.M. CPD-photolyase adenovirus-mediated gene transfer in normal and DNA-repair-deficient human cells. J. Cell Sci. 117 (2004) 3579-3592
41. Nakajima S., Lan L., Kanno S., Takao M., Yamamoto K., Eker A.P., and Yasui A. UV light-induced DNA damage and tolerance for the survival of nucleotide excision repair-deficient human cells. J. Biol. Chem. 279 (2004) 46674-46677
42. Lin Q., Clark A.B., McCulloch S.D., Yuan T., Bronson R.T., Kunkel T.A., and Kucherlapati R. Increased susceptibility to UV-induced skin carcinogenesis in polymerase η-deficient mice. Cancer Res. 66 (2006) 87-94