In vitro anti-tumor activity of isorhamnetin isolated from Hippophae rhamnoides L. against BEL-7402 cells

Pharmacological Research

Volumn 54, Issue 3, 2006, Pages 186-194

  Teng, Bao song ^a   Lu, Yan Hua ^a   Wang, Zheng Tao ^b   Tao, Xin Yi ^a   Wei, Dong Zhi ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SHANGHAI UNIVERSITY   (China)

Author keywords

Apoptosis; Flavonoids; Isorhamnetin; Proliferation; Tumor

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CELL DNA; FLAVONOL DERIVATIVE; HIPPOPHAE RHAMNOIDES EXTRACT; ISORHAMNETIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL LEVEL; CELL MEMBRANE PERMEABILITY; CHINESE MEDICINE; CHROMATIN; CHRONOPHARMACOLOGY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIPLOIDY; DNA CONTENT; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG PENETRATION; DRUG POTENCY; DRUG SCREENING; DRUG TRANSPORT; FLOW CYTOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOPHAE RHAMNOIDES; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; INTRACELLULAR TRANSPORT; LIVER CELL CARCINOMA; PRIORITY JOURNAL; STAINING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL NUCLEUS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLAVONOLS; G1 PHASE; HIPPOPHAE; HUMANS; LIVER NEOPLASMS;

EID: 33746330765     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2006.04.007     Document Type: Article

References (44)

1. Abdulla M., and Gruber P. Role of diet modification in cancer prevention. Biofactors 12 (2000) 45-51
2. Cheng T.J. Protective action of seed oil of Hippophae rhamnoides L. (HR) against experimental liver injury in mice. Zhong hua Yu Fang Yi Xue Za Zhi 26 (1992) 227-229
3. Gao X., Ohlander M., Jeppsson N., Bjork L., and Trajkovski V. Changes in antioxidant effects and their relationship to phytonutrients in fruits of sea buckthorn (Hippophae rhamnoides L.) during maturation. J Agric Food Chem 48 (2000) 1485-1490
4. Li T.S.C., and Wang L.C.H. Physiological components and health effects of ginseng, Echinacea and sea buckthorn. In: Mazza G. (Ed). Functional foods, biochemical and processing aspects. Technomic (1998) 329-356
5. Suleyman H., Demirezer L.O., Buyukokuroglu M.E., Akcay M.F., Gepdiremen A., Banoglu Z.N., et al. Antiulcerogenic effect of Hippophae rhamnoides L. Phytother Res 15 (2001) 625-627
6. Beveridge T., Li T.S., Oomah B.D., and Smith A. Seabuckthorn products: manufacture and composition. J Agric Food Chem 47 (1999) 3480-3488
7. Xu M.Y., Sun X.X., and Tong W.X. Medical research and development of seabuckthorn. Hippophae 7 (1994) 32-40
8. Bazaron E.G., and Tsybikova DTs. Seabuckthorn is the remedy of Indo-Tibet medicine. Rastit Resur 14 (1978) 67-69
9. Matafonov II. Khundan-ova LL, editor. Seabuckthorn (an influence on the animal organism). Novosibirsk, Nauka, Sibirdiv; 1983, p. 165
10. Shapiro D.K., Garanovich I.M., Anikhimovskaya L.V., Narizhnaya T.I., and Vereskovskii V.V. Biochemical and morphological characteristics of prospective forms of seabuckthorn populations of North Azerbaijan. Rastit Resur 14 1 (1978) 60-64
11. Vermenichev S.M. Experimental study of toxicity and anti-tumor activity of natural and synthetic compounds of pyrone series. Phenolic compounds and their physiological properties. Properties. Proceedings of the 2nd All-union Symposium on Phenolic Compounds, Held 17-21 May 1971 in Alma-Ata, 'Nauka' Kazakh. SSR (1973) 210-214
12. Tsybikava D.Ts., Rasputina D.B., Zalykeeva D.N., Darzhapova G.Zh., and Khundanova L.L. A study of leaves and the oil cake of seabuckthorn. Biol Chem Pharmacol Seabuckthorn (1983) 107-109
13. Geetha S., SaiRam M., Singh V., Ilavazhagan G., and Sawhney R.C. Anti-oxidant and immunomodulatory properties of seabuckthorn (Hippophae rhamnoides) - an in-vitro study. J Ethnopharmacol 79 (2002) 373-378
14. Ganju L., Padawad Y., Singh R., Karan D., Chanda S., Chopra M.K., et al. Anti-inflammatory activity of Seabuckthorn (Hippophae rhamnoides) leaves. Int Immunopharmacol 5 (2005) 1675-1684
15. Oh H.M., Kwon B.M., Baek N.I., Kim S.H., Chung I.S., Park M.H., et al. Inhibitory activity of isorhamnetin from Persicaria thunbergii on Farnesyl Protein Transferase. Arch Pharm Res 28 (2005) 169-171
16. Echeverry C., Blasina F., Arredondo F., Ferreira M., Abin-Carriquiry J.A., Vasquez L., et al. Cytoprotection by neutral fraction of tannat red wine against oxidative stress-induced cell death. J Agric Food Chem 52 (2004) 7395-7399
17. Kuti J.O. Antioxidant compounds from four Opuntia cactus pear fruit varieties. Food Chem 85 (2004) 527-533
18. Ibarra M., Perez-Vizcaino F., Cogolludo A., Duarte J., Zaragoza-Arnaez F., Lopez-Lopez J.G., et al. Cardiovascular effects of isorhamnetin and quercetin in isolated rat and porcine vascular smooth muscle and isolated rat atria. Planta Med 68 (2002) 307-310
19. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Meth 65 (1983) 55-63
20. Ye C.L., Liu J.W., Wei D.Z., Lu Y.H., and Qian F. In vitro anti-tumor activity of 2′,4′-dihydroxy-6′-methoxy-3′, 5′-dimethylchalcone against six established human cancer cell lines. Pharmacol Res 50 (2004) 505-510
21. Liu Y.B. Understanding the biological activity of amyloid proteins in vitro: from inhibited cellular MTT reduction to altered cellular cholesterol homeostatis. Prog Neuro-Psychopharmacol Biol Psychiat 23 (1999) 377-395
22. Ader P., Wessmann A., and Wolffram S. Bioavailability and metabolism of the flavonol quartering in the pig. Free Rad Biol Med 28 (2000) 1056-1067
23. Claudine M., Odile T., Françoise R., Georgine A., Christian D., and Christian R. Dietary quercetin is recovered in rat plasma as conjugated derivatives of isorhamnetin and quercetin. Nutr Biochem 7 (1996) 375-380
24. Gorczyca W., Gong J., Ardelt B., Trafanos F., and Darzynkiewicz Z. The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. Cancer Res 53 (1993) 3186-3192
25. Mccabe M.J.J., and Orrenius S. Genistein induces apoptosis in immature human thymocytes by inhibiting topoisomerase-II. Biochem Biophys Res Commun 194 (1993) 944-950
26. Bergamaschi G., Rosti V., Danova M., Ponchio L., Lucotti C., and Cazzola M. Inhibition of tyrosine phosphorylation induce apoptosis in human leukemia cells. Leukemia 7 (1993) 2012-2018
27. Kuo S.M. Antiproliferative potency of structurally distinct dietary flavonoid on human colon cancer cells. Cancer Lett 110 (1996) 41-48
28. Wei Y.Q., Zhao X., Kariya Y., Rukata H., Teshigawara K., and Uchida A. Induction of apoptosis by quercetin: involvement of heat shock protein. Cancer Res 54 (1994) 4952-4957
29. Csokay B., Prajda N., Weber G., and Olah E. Molecular mechanisms in the antiproliferative action of quercetin. Life Sci 60 (1997) 2157-2163
30. Chan F.L., Choi Z.Y., and Huang Y. Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin. Cancer Lett 160 (2000) 218-219
31. Iwashita K., Kobori M., Yamaki K., and Tsushida T. Flavonoids inhibit cell growth and induce apoptosis in B16 melanoma 4A5 cells. Biosci Biotechnol Biochem 64 (2000) 1813-1820
32. Kobori M., Iwashita K., Shinmoto H., and Tsushida T. Phloretin-induced apoptosis in B16 melanoma 4A5 cells and HL-60 huamn leukemia cells. Biosci Biotechnol Biochem 63 (1999) 719-725
33. Khatab A.M., Haggag E.G., and Grace M.H. Cytotoxic investigation of Cynara sibthorpiana. Asian J Chem 18 1 (2006) 423-431
34. Chen J., and Kang J.H. Quercetin and trichostatin. A cooperatively kill human leukemia cells. Pharmazie 60 11 (2005) 856-860
35. Niering P., Michels G., Watjen W., Ohler S., Steffan B., Chovolou Y., et al. Protective and detrimental effects of kaempferol in rat H4IIE cells: implication of oxidative stress and apoptosis. Toxicol Appl Pharmacol 209 2 (2005) 114-122
36. Chung S.Y., Sung M.K., Kim N.H., Jang J.O., Go E.J., and Lee H.J. Inhibition of P-glycoprotein by natural products in human breast cancer cells. Arch Pharm Res 28 7 (2005) 823-828
37. Wang Y., Cao J., Weng J.-H., and Zeng S. Simultaneous determination of quercetin, kaempferol and isorhamnetin accumulated human beast cancer cells, by high-performance liquid chromatography. J Pharm Biomed Anal 39 (2005) 328-333
38. Borst P., and Elferink R.O. Ann Rev Biochem 71 (2002) 537-592
39. Faber K.N., Muller M., and Jansen P.L. Adv Drug Deliv Rev 55 (2003) 107-124
40. Yang C.-L., Wang Z.-R., Tao D.-C., and Peng T. Effect of isorhamnetin on bcl-2 gene expression of HeLa cell. Med J West China 1 (2003) 196-198
41. Pomilio A.B., Sola G.A.R., Mayer A.M.S., and Rumi L.S. Antitumor and cytotoxic screen of 5,6,7-trisubstituted flavones from Gomphrena martiana. J Ethnopharmacol 44 (1994) 25-33
42. Yin X.M., Oltvai Z.N., Veis-Novack D.J., Linette G.P., and Korsmeyer S.J. Bcl-2 gene family and the regulation of programmed cell death. Cold Spring Harbor Symp Quant Biol 59 (1994) 387-393
43. Hockenbery D.M., Oltvai Z.N., Yin X.M., Milliman C.L., and Korsmeyer S.J. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75 (1993) 241-251
44. Reed J.C. Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance. Curr Opin Oncol 7 (1995) 541-546