Computational model for the IGF-II/IGF2R complex that is predictive of mutational and surface plasmon resonance data

Proteins: Structure, Function and Genetics

Volumn 64, Issue 3, 2006, Pages 758-768

  Roche, Philippe ^a,c   Brown, James ^a   Denley, Adam ^b,d   Forbes, Briony E ^b   Wallace, John C ^b   Jones, E Yvonne ^a   Esnouf, Robert M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c AIX MARSEILLE UNIVERSITÉ   (France)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

3D Dock; Biacore; Docking; Insulin like growth factor; Protein protein interactions; Structure

Indexed keywords

SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR;

ARTICLE; BINDING KINETICS; COMPLEX FORMATION; COMPUTER MODEL; COMPUTER PROGRAM; CRYSTAL STRUCTURE; MOLECULAR DYNAMICS; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; SURFACE PLASMON RESONANCE;

BINDING SITES; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, IGF TYPE 2; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PLASMON RESONANCE;

EID: 33746267366     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21035     Document Type: Article

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