메뉴 건너뛰기




Volumn 177, Issue 3, 2006, Pages 1500-1509

The thymus plays a role in oral tolerance in experimental autoimmune encephalomyelitis

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GLUCOCORTICOID; MYELIN BASIC PROTEIN; MYELIN PROTEIN; OVALBUMIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 33746210319     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.3.1500     Document Type: Article
Times cited : (28)

References (59)
  • 1
    • 0033546603 scopus 로고    scopus 로고
    • Multiple sclerosis in children under 6 years of age
    • Ruggieri, M., A. Polizzi, L. Pavone, and L. M. Grimaldi. 1999. Multiple sclerosis in children under 6 years of age. Neurology 53: 478-474.
    • (1999) Neurology , vol.53 , pp. 478-1474
    • Ruggieri, M.1    Polizzi, A.2    Pavone, L.3    Grimaldi, L.M.4
  • 4
    • 0029034068 scopus 로고
    • Immunological aspects of experimental allergic encephalomyelitis and multiple sclerosis
    • Martin, R., and H. F. McFarland. 1995. Immunological aspects of experimental allergic encephalomyelitis and multiple sclerosis. Crit. Rev. Clin. Lab. Sci. 32: 121-182.
    • (1995) Crit. Rev. Clin. Lab. Sci. , vol.32 , pp. 121-182
    • Martin, R.1    McFarland, H.F.2
  • 5
    • 0025246367 scopus 로고
    • The T lymphocyte in experimental allergic encephalomyelitis
    • Zamvil, S. S., and L. Steinman. 1990. The T lymphocyte in experimental allergic encephalomyelitis. Annu. Rev. Immunol. 8: 579-621.
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 579-621
    • Zamvil, S.S.1    Steinman, L.2
  • 6
    • 0036345337 scopus 로고    scopus 로고
    • Origin of regulatory T cells with known specificity for antigen
    • Apostolou, I., A. Sarukhan, L. Klein, and H. von Boehmer. 2002. Origin of regulatory T cells with known specificity for antigen. Nat. Immunol. 3: 756-763.
    • (2002) Nat. Immunol. , vol.3 , pp. 756-763
    • Apostolou, I.1    Sarukhan, A.2    Klein, L.3    Von Boehmer, H.4
  • 8
    • 0027504747 scopus 로고
    • The human myelin basic protein gene is included within a 179-kilobase transcription unit: Expression in the immune and central nervous systems
    • Pribyl, T. M., C. W. Campagnoni, K. Kampf, T. Kashima, V. W. Handley, J. McMahon, and A. T. Campagnoni. 1993. The human myelin basic protein gene is included within a 179-kilobase transcription unit: expression in the immune and central nervous systems. Proc. Natl. Acad. Sci. USA 90: 10695-10699.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10695-10699
    • Pribyl, T.M.1    Campagnoni, C.W.2    Kampf, K.3    Kashima, T.4    Handley, V.W.5    McMahon, J.6    Campagnoni, A.T.7
  • 9
    • 0027486298 scopus 로고
    • Identification of an embryonic isoform of myelin basic protein that is expressed widely in the mouse embryo
    • Mathisen, P. M., S. Pease, J. Garvey, L. Hood, and C. Readhead. 1993. Identification of an embryonic isoform of myelin basic protein that is expressed widely . in the mouse embryo. Proc. Natl. Acad. Sci. USA 90: 10125-10129.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10125-10129
    • Mathisen, P.M.1    Pease, S.2    Garvey, J.3    Hood, L.4    Readhead, C.5
  • 10
    • 0030589288 scopus 로고    scopus 로고
    • Thymic expression of myelin basic protein (MBP)
    • Fritz, R. B., and M.-L. Zhao. 1996. Thymic expression of myelin basic protein (MBP). J. Immunol. 157: 5249-5253.
    • (1996) J. Immunol. , vol.157 , pp. 5249-5253
    • Fritz, R.B.1    Zhao, M.-L.2
  • 11
    • 0031756654 scopus 로고    scopus 로고
    • Myelin protein expression in lymphoid tissues: Implications for peripheral tolerance
    • Voskuhl, R. R. 1998. Myelin protein expression in lymphoid tissues: implications for peripheral tolerance. Immunol. Rev. 164: 81-92.
    • (1998) Immunol. Rev. , vol.164 , pp. 81-92
    • Voskuhl, R.R.1
  • 12
    • 0028849807 scopus 로고
    • Major histocompatibility complex binding affinity of an antigenic determinant is crucial for the differential secretion of interleukin 4/5 or interferon γ by T cells
    • Kumar, V., V. Bhardwaj, L. Scares, J. Alexan-der, A. Sette, and E. Sercarz. 1995. Major histocompatibility complex binding affinity of an antigenic determinant is crucial for the differential secretion of interleukin 4/5 or interferon γ by T cells. Proc. Natl. Acad. Sci. USA 92: 9510-9514.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9510-9514
    • Kumar, V.1    Bhardwaj, V.2    Scares, L.3    Alexan-der, J.4    Sette, A.5    Sercarz, E.6
  • 14
    • 0028824098 scopus 로고
    • Low avidity recognition of self-antigen by T cells permits escape from central tolerance
    • Liu, G. Y., P. J. Fairchild, R. M. Smith, J. R. Prowie, D. Kioussis, and D. C. Wraith. 1995. Low avidity recognition of self-antigen by T cells permits escape from central tolerance. Immunity 3: 407-415.
    • (1995) Immunity , vol.3 , pp. 407-415
    • Liu, G.Y.1    Fairchild, P.J.2    Smith, R.M.3    Prowie, J.R.4    Kioussis, D.5    Wraith, D.C.6
  • 16
    • 0036345337 scopus 로고    scopus 로고
    • Origin of regulatory T cells with known specificity for antigen
    • Apostolou, I., A. Sarukhan, L. Klein, and H. von Boehmer. 2002. Origin of regulatory T cells with known specificity for antigen. Nat. Immunol. 3: 756-763.
    • (2002) Nat. Immunol. , vol.3 , pp. 756-763
    • Apostolou, I.1    Sarukhan, A.2    Klein, L.3    Von Boehmer, H.4
  • 17
    • 0035316363 scopus 로고    scopus 로고
    • Policing the regulators
    • Sakaguchi, S. 2001. Policing the regulators. Nat. Immunol. 2: 283-284.
    • (2001) Nat. Immunol. , vol.2 , pp. 283-284
    • Sakaguchi, S.1
  • 18
    • 0029164864 scopus 로고
    • Mechanisms of acquired thymic tolerance in experimental autoimmune encephalomyelitis: Thymic dendritic-enriched cells induce specific peripheral T cell unresponsiveness in vivo
    • Khoury, S. J., L. Gallon, W. Chen, K. Betres, M. E. Russell, W. W. Hancock, C. B. Carpenter, M. H. Sayegh, and H. L. Weiner. 1995. Mechanisms of acquired thymic tolerance in experimental autoimmune encephalomyelitis: thymic dendritic-enriched cells induce specific peripheral T cell unresponsiveness in vivo. J. Exp. Med. 182: 357-366.
    • (1995) J. Exp. Med. , vol.182 , pp. 357-366
    • Khoury, S.J.1    Gallon, L.2    Chen, W.3    Betres, K.4    Russell, M.E.5    Hancock, W.W.6    Carpenter, C.B.7    Sayegh, M.H.8    Weiner, H.L.9
  • 19
    • 0031939695 scopus 로고    scopus 로고
    • Mechanisms of acquired thymic tolerance in vivo: Intrathymic injection of antigen induces apoptosis of thymocytes and peripheral T cell anergy
    • Chen, W., M. H. Sayegh, and S. J. Khoury. 1998. Mechanisms of acquired thymic tolerance in vivo: intrathymic injection of antigen induces apoptosis of thymocytes and peripheral T cell anergy. J. Immunol. 160: 1504-1508.
    • (1998) J. Immunol. , vol.160 , pp. 1504-1508
    • Chen, W.1    Sayegh, M.H.2    Khoury, S.J.3
  • 20
    • 0027255487 scopus 로고
    • Acquired tolerance to experimental autoimmune encephalomyelitis by intrathymic injection of myelin basic protein or its major encephalitogenic peptide
    • Khoury, S. J., M. H. Sayegh, W. W. Hancock, L. C. B. Gallon, Carpenter, and H. L. Weiner. 1993. Acquired tolerance to experimental autoimmune encephalomyelitis by intrathymic injection of myelin basic protein or its major encephalitogenic peptide. J. Exp. Med. 178: 559-566.
    • (1993) J. Exp. Med. , vol.178 , pp. 559-566
    • Khoury, S.J.1    Sayegh, M.H.2    Hancock, W.W.3    Gallon, L.C.B.4    Carpenter5    Weiner, H.L.6
  • 21
    • 0033555417 scopus 로고    scopus 로고
    • Acquired thymic tolerance: Role of CTLA4 in the initiation and maintenance of tolerance in a clinically relevant autoimmune disease model
    • Issazadeh, S., M. Zhang, M. H. Sayegh, and S. J. Khoury. 1999. Acquired thymic tolerance: role of CTLA4 in the initiation and maintenance of tolerance in a clinically relevant autoimmune disease model. J. Immunol. 162: 761-765.
    • (1999) J. Immunol. , vol.162 , pp. 761-765
    • Issazadeh, S.1    Zhang, M.2    Sayegh, M.H.3    Khoury, S.J.4
  • 22
    • 0023927111 scopus 로고
    • Suppression of experimental autoimmune encephalomyelitis by the oral administration of myelin basic protein
    • Bitar, D. M., and C. C. Whitacre. 1988. Suppression of experimental autoimmune encephalomyelitis by the oral administration of myelin basic protein. Cell. Immunol. 112: 364-370.
    • (1988) Cell. Immunol. , vol.112 , pp. 364-370
    • Bitar, D.M.1    Whitacre, C.C.2
  • 23
    • 0026042008 scopus 로고
    • Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy
    • Whitacre, C. C., I. E. Gienapp, C. G. Orosz, and D. M. Bitar. 1991. Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy. J. Immunol. 147: 2155-2163.
    • (1991) J. Immunol. , vol.147 , pp. 2155-2163
    • Whitacre, C.C.1    Gienapp, I.E.2    Orosz, C.G.3    Bitar, D.M.4
  • 24
    • 0028146261 scopus 로고
    • Antigen-driven tissue-specific suppression following oral tolerance: Orally administered myelin basic protein suppresses proteolipid protein-induced experimental autoimmune encephalomyelitis in the SJL mouse
    • al-Sabbagh, A., A. Miller, L. M. Santos, and H. L. Weiner. 1994. Antigen-driven tissue-specific suppression following oral tolerance: orally administered myelin basic protein suppresses proteolipid protein-induced experimental autoimmune encephalomyelitis in the SJL mouse. Eur. J. Immunol. 24: 2104-2109.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2104-2109
    • Al-Sabbagh, A.1    Miller, A.2    Santos, L.M.3    Weiner, H.L.4
  • 25
    • 0029741439 scopus 로고    scopus 로고
    • Inhibition of relapsing experimental autoimmune encephalomyelitis in SJL mice by feeding the immunodominant PLP139-151 peptide
    • Karpus, W. J., K. J. Kennedy, W. S. Smith, and S. D. Miller. 1996. Inhibition of relapsing experimental autoimmune encephalomyelitis in SJL mice by feeding the immunodominant PLP139-151 peptide. J. Neurosci. Res. 45: 410-423.
    • (1996) J. Neurosci. Res. , vol.45 , pp. 410-423
    • Karpus, W.J.1    Kennedy, K.J.2    Smith, W.S.3    Miller, S.D.4
  • 26
    • 0030293682 scopus 로고    scopus 로고
    • Suppression of murine chronic relapsing experimental autoimmune encephalomyelitis by the oral administration of myelin basic protein
    • Meyer, A. L., J. M. Benson, I. E. Gienapp, K. L. Cox, and C. C. Whitacre. 1996. Suppression of murine chronic relapsing experimental autoimmune encephalomyelitis by the oral administration of myelin basic protein. J. Immunol. 157: 4230-4238.
    • (1996) J. Immunol. , vol.157 , pp. 4230-4238
    • Meyer, A.L.1    Benson, J.M.2    Gienapp, I.E.3    Cox, K.L.4    Whitacre, C.C.5
  • 27
    • 0033563260 scopus 로고    scopus 로고
    • Oral administration of myelin basic protein is superior to myelin in suppressing established relapsing experimental autoimmune encephalomyelitis
    • Benson, J. M., S. S. Stuckman, K. L. Cox, R. M. Wardrop, I. E. Gienapp, A. H. Cross, J. L. Trotter, and C. C. Whitacre. 1999. Oral administration of myelin basic protein is superior to myelin in suppressing established relapsing experimental autoimmune encephalomyelitis. J. Immunol. 162: 6247-6254.
    • (1999) J. Immunol. , vol.162 , pp. 6247-6254
    • Benson, J.M.1    Stuckman, S.S.2    Cox, K.L.3    Wardrop, R.M.4    Gienapp, I.E.5    Cross, A.H.6    Trotter, J.L.7    Whitacre, C.C.8
  • 28
    • 0037372887 scopus 로고    scopus 로고
    • Induction of low dose oral tolerance in monocyte chemoattractant protein-1- and CCR2-deficient mice
    • Gonnella, P. A., D. Kodali, and H. L. Weiner. 2003. Induction of low dose oral tolerance in monocyte chemoattractant protein-1- and CCR2-deficient mice. J. Immunol. 170: 2316-2322.
    • (2003) J. Immunol. , vol.170 , pp. 2316-2322
    • Gonnella, P.A.1    Kodali, D.2    Weiner, H.L.3
  • 29
    • 0034991196 scopus 로고    scopus 로고
    • Mucosal administration of IL-10 enhances oral tolerance in autoimmune encephalomyelitis and diabetes
    • Slavin, A. J., R. Maron, and H. L. Weiner. 2001. Mucosal administration of IL-10 enhances oral tolerance in autoimmune encephalomyelitis and diabetes. Int. Immunol. 13: 825-833.
    • (2001) Int. Immunol. , vol.13 , pp. 825-833
    • Slavin, A.J.1    Maron, R.2    Weiner, H.L.3
  • 30
    • 0035340263 scopus 로고    scopus 로고
    • Rapid depletion of peripheral antigen-specific T cells in TCR-transgenic mice after oral administration of myelin basic protein
    • Meyer, A. L., J. Benson, F. Song, N. Javed, I. E. Gienapp, J. Goverman, T. A. Brabb, L. Hood, and C. C. Whitacre. 2001. Rapid depletion of peripheral antigen-specific T cells in TCR-transgenic mice after oral administration of myelin basic protein. J. Immunol. 166: 5773-5781.
    • (2001) J. Immunol. , vol.166 , pp. 5773-5781
    • Meyer, A.L.1    Benson, J.2    Song, F.3    Javed, N.4    Gienapp, I.E.5    Goverman, J.6    Brabb, T.A.7    Hood, L.8    Whitacre, C.C.9
  • 31
    • 0037006430 scopus 로고    scopus 로고
    • Differences between two strains of myelin basic protein (MBP) TCR transgenic mice: Implications for tolerance induction
    • Song, F., R. M. Wardrop, I. E. Gienapp, S. S. Stuckman, J. Goverman, and C. C. Whitacre. 2002. Differences between two strains of myelin basic protein (MBP) TCR transgenic mice: implications for tolerance induction. J. Autoimmun. 18: 27-37.
    • (2002) J. Autoimmun. , vol.18 , pp. 27-37
    • Song, F.1    Wardrop, R.M.2    Gienapp, I.E.3    Stuckman, S.S.4    Goverman, J.5    Whitacre, C.C.6
  • 34
    • 0035113503 scopus 로고    scopus 로고
    • Oral administration of insulin to neonates suppresses spontaneous and cyclophosphamide induced diabetes in the NOD mouse
    • Maron, R., M. Guerau-de-Arellano, X. Zhang, and H. L. Weiner. 2001. Oral administration of insulin to neonates suppresses spontaneous and cyclophosphamide induced diabetes in the NOD mouse. J. Autoimmun. 16: 21-28.
    • (2001) J. Autoimmun. , vol.16 , pp. 21-28
    • Maron, R.1    Guerau-De-Arellano, M.2    Zhang, X.3    Weiner, H.L.4
  • 35
    • 0030847054 scopus 로고    scopus 로고
    • Oral tolerance: Immune mechanisms and treatment of autoimmune diseases
    • Weiner, H. L. 1997. Oral tolerance: immune mechanisms and treatment of autoimmune diseases. Immunol. Today 18: 335-343.
    • (1997) Immunol. Today , vol.18 , pp. 335-343
    • Weiner, H.L.1
  • 36
    • 0035186416 scopus 로고    scopus 로고
    • Induction and mechanism of action of transforming growth factor β-secreting Th3 regulatory cells
    • Weiner, H. L. 2001. Induction and mechanism of action of transforming growth factor β-secreting Th3 regulatory cells. Immunol. Rev. 182: 207-214.
    • (2001) Immunol. Rev. , vol.182 , pp. 207-214
    • Weiner, H.L.1
  • 37
    • 0034716925 scopus 로고    scopus 로고
    • Regulatory T cells: Key controllers of immunologic self-tolerance
    • Sakaguchi, S. 2000. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 101: 455-458.
    • (2000) Cell , vol.101 , pp. 455-458
    • Sakaguchi, S.1
  • 38
    • 7144259082 scopus 로고    scopus 로고
    • Regulatory CD4 T cells: Expression of IL-2R α chain, resistance to clonal deletion and IL-2 dependency
    • Papiernik, M., M. L. de Moraes, C. Pontoux, F. Vasseur, and C. Penit. 1998. Regulatory CD4 T cells: expression of IL-2R α chain, resistance to clonal deletion and IL-2 dependency. Int. Immunol. 10: 371-378.
    • (1998) Int. Immunol. , vol.10 , pp. 371-378
    • Papiernik, M.1    De Moraes, M.L.2    Pontoux, C.3    Vasseur, F.4    Penit, C.5
  • 39
    • 0035399985 scopus 로고    scopus 로고
    • +CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen
    • +CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen. J. Immunol. 167: 188-195.
    • (2001) J. Immunol. , vol.167 , pp. 188-195
    • Thorstenson, K.M.1    Khoruts, A.2
  • 40
    • 0028102655 scopus 로고
    • High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice
    • Lafaille, J. J., K. Nagashima, M. Katsuki, and S. Tonegawa. 1994. High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell 78: 399-408.
    • (1994) Cell , vol.78 , pp. 399-408
    • Lafaille, J.J.1    Nagashima, K.2    Katsuki, M.3    Tonegawa, S.4
  • 41
    • 0028929345 scopus 로고
    • An improved technique of thymectomy in the adult mouse
    • DeMatteo, R. P., J. F. Markmann, and S. E. Raper. 1995. An improved technique of thymectomy in the adult mouse. Transplantation 59: 787-789.
    • (1995) Transplantation , vol.59 , pp. 787-789
    • DeMatteo, R.P.1    Markmann, J.F.2    Raper, S.E.3
  • 42
    • 0015955514 scopus 로고
    • Studies on the species-variability of experimental allergic encephalomyelitis in guinea pigs and rats
    • Swanborg, R. H., J. E. Swierkosz, and R. G. Saieg. 1974. Studies on the species-variability of experimental allergic encephalomyelitis in guinea pigs and rats. J. Immunol. 112: 594-600.
    • (1974) J. Immunol. , vol.112 , pp. 594-600
    • Swanborg, R.H.1    Swierkosz, J.E.2    Saieg, R.G.3
  • 43
    • 0028466130 scopus 로고
    • Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo
    • Keamey, E. R., K. A. Pape, D. Y., Loh, and M. K. Jenkins. 1994. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1: 327-339.
    • (1994) Immunity , vol.1 , pp. 327-339
    • Keamey, E.R.1    Pape, K.A.2    Loh, D.Y.3    Jenkins, M.K.4
  • 44
    • 0032863914 scopus 로고    scopus 로고
    • Differential age effect of oral administration of an antigen on antibody response: An induction of tolerance in young mice but enhancement of immune response in old mice
    • Wakabayashi, A., M. Utsuyama, T. Hosoda, K. Sato, and K. Hirokawa. 1999. Differential age effect of oral administration of an antigen on antibody response: an induction of tolerance in young mice but enhancement of immune response in old mice. Mech. Ageing Dev. 109: 191-201.
    • (1999) Mech. Ageing Dev. , vol.109 , pp. 191-201
    • Wakabayashi, A.1    Utsuyama, M.2    Hosoda, T.3    Sato, K.4    Hirokawa, K.5
  • 45
    • 0034698828 scopus 로고    scopus 로고
    • Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells
    • Cho, B. K., V. P. Rao, Q. Ge, H. N. Eisen, and J. Chen. 2000. Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells. J. Exp. Med. 192: 549-556.
    • (2000) J. Exp. Med. , vol.192 , pp. 549-556
    • Cho, B.K.1    Rao, V.P.2    Ge, Q.3    Eisen, H.N.4    Chen, J.5
  • 46
    • 0034663776 scopus 로고    scopus 로고
    • Cutting edge: Naive T cells masquerading as memory cells
    • Murali-Krishna, K., and R. Ahmed. 2000. Cutting edge: naive T cells masquerading as memory cells. J. Immunol. 165: 1733-1737.
    • (2000) J. Immunol. , vol.165 , pp. 1733-1737
    • Murali-Krishna, K.1    Ahmed, R.2
  • 48
    • 0035477990 scopus 로고    scopus 로고
    • + T cells: Costimulatory requirements and role in memory formation
    • + T cells: costimulatory requirements and role in memory formation. J. Immunol. 167: 3699-3707.
    • (2001) J. Immunol. , vol.167 , pp. 3699-3707
    • Gudmundsdottir, H.1    Turka, L.A.2
  • 49
    • 0037062420 scopus 로고    scopus 로고
    • Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice
    • Hori, S., M. Haury, A. Coutinho, and J. Demengeot. 2002. Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice. Proc. Natl. Acad. Sci. USA 99: 8213-8218.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 8213-8218
    • Hori, S.1    Haury, M.2    Coutinho, A.3    Demengeot, J.4
  • 51
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • Bluestone, J. A., and A. K. Abbas. 2003. Natural versus adaptive regulatory T cells. Nat. Rev. Immunol. 3: 253-257.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 253-257
    • Bluestone, J.A.1    Abbas, A.K.2
  • 55
    • 0030890603 scopus 로고    scopus 로고
    • Mouse CD1-specific NK1 T cells: Development, specificity, and function
    • Bendelac, A., M. N. Rivera, S. H. Park, and J. H. Roark. 1997. Mouse CD1-specific NK1 T cells: development, specificity, and function. Annu. Rev. Immunol. 15: 535-562.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 535-562
    • Bendelac, A.1    Rivera, M.N.2    Park, S.H.3    Roark, J.H.4
  • 58
    • 0028267677 scopus 로고
    • Turnover of naive- and memory-phenotype T cells
    • Tough, D. F., and J. Sprent. 1994. Turnover of naive- and memory-phenotype T cells. J. Exp. Med. 179: 1127-1135.
    • (1994) J. Exp. Med. , vol.179 , pp. 1127-1135
    • Tough, D.F.1    Sprent, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.