Differential age effect of oral administration of an antigen on antibody response: An induction of tolerance in young mice but enhancement of immune response in old mice

Mechanisms of Ageing and Development

Volumn 109, Issue 3, 1999, Pages 191-201

  Wakabayashi, Ayako ^a,b,c   Utsuyama, Masanori ^b,c   Hosoda, Tomoko ^c,d   Sato, Kazuto ^d   Hirokawa, Katsuiku ^b  

^a Japan Found for Aging and Health   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^d JAPAN WOMEN'S UNIVERSITY   (Japan)

Author keywords

Antibody response; Old mice; Oral administration; Sheep red blood cells; Tolerance

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY;

AGE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SHEEP ERYTHROCYTE; T LYMPHOCYTE;

ADMINISTRATION, ORAL; AGING; ANIMALS; ANTIBODIES; ANTIGENS; B-LYMPHOCYTES; ERYTHROCYTES; FEMALE; IMMUNE TOLERANCE; INJECTIONS, INTRAPERITONEAL; MALE; MICE; MICE, INBRED C57BL; SHEEP; T-LYMPHOCYTES;

OVIS ARIES;

EID: 0032863914     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(99)00036-6     Document Type: Article

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