-
1
-
-
2342595765
-
Trends in antimicrobial drug development: implications for the future
-
Spellberg B., Powers J.H., Brass E.P., Miller L.G., and Edwards Jr. J.E. Trends in antimicrobial drug development: implications for the future. Clin Infect Dis 38 (2004) 1279-1286
-
(2004)
Clin Infect Dis
, vol.38
, pp. 1279-1286
-
-
Spellberg, B.1
Powers, J.H.2
Brass, E.P.3
Miller, L.G.4
Edwards Jr., J.E.5
-
2
-
-
0025156911
-
Discovery and development of new antimicrobial agents
-
Gootz T.D. Discovery and development of new antimicrobial agents. Clin Microbiol Rev 3 (1990) 13-31
-
(1990)
Clin Microbiol Rev
, vol.3
, pp. 13-31
-
-
Gootz, T.D.1
-
3
-
-
0034678055
-
Harnessing the power of the genome in the search for new antibiotics
-
Rosamond J., and Allsop A. Harnessing the power of the genome in the search for new antibiotics. Science 287 (2000) 1973-1976
-
(2000)
Science
, vol.287
, pp. 1973-1976
-
-
Rosamond, J.1
Allsop, A.2
-
4
-
-
0036771389
-
Novel approaches to antimicrobial therapy: peptide deformylase
-
Bacterial peptide deformylase (PDF) is one of the best and few examples of mechanism-based rational drug design. Because it is absent in humans and required for bacterial survival, PDF is a promising antimicrobial target, and already a few PDF inhibitors have entered clinical trials.
-
Waller A.S., and Clements J.M. Novel approaches to antimicrobial therapy: peptide deformylase. Curr Opin Drug Discov Devel 5 (2002) 785-792. Bacterial peptide deformylase (PDF) is one of the best and few examples of mechanism-based rational drug design. Because it is absent in humans and required for bacterial survival, PDF is a promising antimicrobial target, and already a few PDF inhibitors have entered clinical trials.
-
(2002)
Curr Opin Drug Discov Devel
, vol.5
, pp. 785-792
-
-
Waller, A.S.1
Clements, J.M.2
-
5
-
-
0034717008
-
Granuloma-specific expression of mycobacterium virulence proteins from the glycine-rich PE-PGRS family
-
Ramakrishnan L., Federspiel N.A., and Falkow S. Granuloma-specific expression of mycobacterium virulence proteins from the glycine-rich PE-PGRS family. Science 288 (2000) 1436-1439
-
(2000)
Science
, vol.288
, pp. 1436-1439
-
-
Ramakrishnan, L.1
Federspiel, N.A.2
Falkow, S.3
-
6
-
-
0032561394
-
Attenuation of virulence by disruption of the mycobacterium tuberculosis erp gene
-
Berthet F.X., Lagranderie M., Gounon P., Laurent-Winter C., Ensergueix D., Chavarot P., Thouron F., Maranghi E., Pelicic V., Portnoi D., et al. Attenuation of virulence by disruption of the mycobacterium tuberculosis erp gene. Science 282 (1998) 759-762
-
(1998)
Science
, vol.282
, pp. 759-762
-
-
Berthet, F.X.1
Lagranderie, M.2
Gounon, P.3
Laurent-Winter, C.4
Ensergueix, D.5
Chavarot, P.6
Thouron, F.7
Maranghi, E.8
Pelicic, V.9
Portnoi, D.10
-
7
-
-
0242628703
-
A report on the chemotherapy of bacterial infections
-
Domagk G. A report on the chemotherapy of bacterial infections. Deut Med Woch lxi (1935) 250
-
(1935)
Deut Med Woch
, vol.lxi
, pp. 250
-
-
Domagk, G.1
-
8
-
-
0001568182
-
Activity of p-aminophenylsulfamide in the experimental streptococcal infections of the mouse and rabbit
-
Trefouel J., Nitti F., and Bovet D. Activity of p-aminophenylsulfamide in the experimental streptococcal infections of the mouse and rabbit. CR Seances Soc Biol 120 (1935) 756
-
(1935)
CR Seances Soc Biol
, vol.120
, pp. 756
-
-
Trefouel, J.1
Nitti, F.2
Bovet, D.3
-
9
-
-
0003409643
-
-
Ehrlich P. (Ed), Springer-Verlag
-
In: Ehrlich P. (Ed). Gesammelte Arbeiten (1957), Springer-Verlag
-
(1957)
Gesammelte Arbeiten
-
-
-
11
-
-
0038443820
-
Drosophila melanogaster is a genetically tractable model host for Mycobacterium marinum
-
Dionne M.S., Ghori N., and Schneider D.S. Drosophila melanogaster is a genetically tractable model host for Mycobacterium marinum. Infect Immun 71 (2003) 3540-3550
-
(2003)
Infect Immun
, vol.71
, pp. 3540-3550
-
-
Dionne, M.S.1
Ghori, N.2
Schneider, D.S.3
-
12
-
-
0345170715
-
Exploration of host-pathogen interactions using Listeria monocytogenes and Drosophila melanogaster
-
Mansfield B.E., Dionne M.S., Schneider D.S., and Freitag N.E. Exploration of host-pathogen interactions using Listeria monocytogenes and Drosophila melanogaster. Cell Microbiol 5 (2003) 901-911
-
(2003)
Cell Microbiol
, vol.5
, pp. 901-911
-
-
Mansfield, B.E.1
Dionne, M.S.2
Schneider, D.S.3
Freitag, N.E.4
-
13
-
-
0031446642
-
Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms
-
Lemaitre B., Reichhart J.M., and Hoffmann J.A. Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proc Natl Acad Sci USA 94 (1997) 14614-14619
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14614-14619
-
-
Lemaitre, B.1
Reichhart, J.M.2
Hoffmann, J.A.3
-
14
-
-
0033534534
-
Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model
-
Mahajan-Miklos S., Tan M.W., Rahme L.G., and Ausubel F.M. Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model. Cell 96 (1999) 47-56
-
(1999)
Cell
, vol.96
, pp. 47-56
-
-
Mahajan-Miklos, S.1
Tan, M.W.2
Rahme, L.G.3
Ausubel, F.M.4
-
15
-
-
0033582314
-
Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis
-
Tan M.W., Mahajan-Miklos S., and Ausubel F.M. Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis. Proc Natl Acad Sci USA 96 (1999) 715-720
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 715-720
-
-
Tan, M.W.1
Mahajan-Miklos, S.2
Ausubel, F.M.3
-
16
-
-
0029035765
-
Common virulence factors for bacterial pathogenicity in plants and animals
-
Rahme L.G., Stevens E.J., Wolfort S.F., Shao J., Tompkins R.G., and Ausubel F.M. Common virulence factors for bacterial pathogenicity in plants and animals. Science 268 (1995) 1899-1902
-
(1995)
Science
, vol.268
, pp. 1899-1902
-
-
Rahme, L.G.1
Stevens, E.J.2
Wolfort, S.F.3
Shao, J.4
Tompkins, R.G.5
Ausubel, F.M.6
-
17
-
-
0030725506
-
Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors
-
Rahme L.G., Tan M.W., Le L., Wong S.M., Tompkins R.G., Calderwood S.B., and Ausubel F.M. Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors. Proc Natl Acad Sci USA 94 (1997) 13245-13250
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13245-13250
-
-
Rahme, L.G.1
Tan, M.W.2
Le, L.3
Wong, S.M.4
Tompkins, R.G.5
Calderwood, S.B.6
Ausubel, F.M.7
-
18
-
-
0036185610
-
Tackling both sides of the host-pathogen equation with Caenorhabditis elegans
-
Ewbank J.J. Tackling both sides of the host-pathogen equation with Caenorhabditis elegans. Microbes Infect 4 (2002) 247-256
-
(2002)
Microbes Infect
, vol.4
, pp. 247-256
-
-
Ewbank, J.J.1
-
19
-
-
0242581687
-
The immune response of drosophila
-
Hoffmann J.A. The immune response of drosophila. Nature 426 (2003) 33-38
-
(2003)
Nature
, vol.426
, pp. 33-38
-
-
Hoffmann, J.A.1
-
20
-
-
0037731431
-
Caenorhabditis elegans: an emerging genetic model for the study of innate immunity
-
Kurz C.L., and Ewbank J.J. Caenorhabditis elegans: an emerging genetic model for the study of innate immunity. Nat Rev Genet 4 (2003) 380-390
-
(2003)
Nat Rev Genet
, vol.4
, pp. 380-390
-
-
Kurz, C.L.1
Ewbank, J.J.2
-
21
-
-
0030728460
-
GATA-1 expression pattern can be recapitulated in living transgenic zebrafish using GFP reporter gene
-
Long Q., Meng A., Wang H., Jessen J.R., Farrell M.J., and Lin S. GATA-1 expression pattern can be recapitulated in living transgenic zebrafish using GFP reporter gene. Development 124 (1997) 4105-4111
-
(1997)
Development
, vol.124
, pp. 4105-4111
-
-
Long, Q.1
Meng, A.2
Wang, H.3
Jessen, J.R.4
Farrell, M.J.5
Lin, S.6
-
22
-
-
0032605466
-
Wholemount in situ hybridization of xenopus and zebrafish embryos
-
Broadbent J., and Read E.M. Wholemount in situ hybridization of xenopus and zebrafish embryos. Methods Mol Biol 127 (1999) 57-67
-
(1999)
Methods Mol Biol
, vol.127
, pp. 57-67
-
-
Broadbent, J.1
Read, E.M.2
-
23
-
-
0032619474
-
Zebrafish immunohistochemistry
-
Macdonald R. Zebrafish immunohistochemistry. Methods Mol Biol 127 (1999) 77-88
-
(1999)
Methods Mol Biol
, vol.127
, pp. 77-88
-
-
Macdonald, R.1
-
24
-
-
0033780376
-
Effective targeted gene 'knockdown' in zebrafish
-
Nasevicius A., and Ekker S.C. Effective targeted gene 'knockdown' in zebrafish. Nat Genet 26 (2000) 216-220
-
(2000)
Nat Genet
, vol.26
, pp. 216-220
-
-
Nasevicius, A.1
Ekker, S.C.2
-
25
-
-
1842684987
-
The use of zebrafish to understand immunity
-
Trede N.S., Langenau D.M., Traver D., Look A.T., and Zon L.I. The use of zebrafish to understand immunity. Immunity 20 (2004) 367-379
-
(2004)
Immunity
, vol.20
, pp. 367-379
-
-
Trede, N.S.1
Langenau, D.M.2
Traver, D.3
Look, A.T.4
Zon, L.I.5
-
26
-
-
22844451392
-
Recent advances on the complement system of teleost fish
-
Boshra H., Li J., and Sunyer J.O. Recent advances on the complement system of teleost fish. Fish Shellfish Immunol 20 (2006) 239-262
-
(2006)
Fish Shellfish Immunol
, vol.20
, pp. 239-262
-
-
Boshra, H.1
Li, J.2
Sunyer, J.O.3
-
27
-
-
0347480221
-
Expression analysis of the toll-like receptor and TIR domain adaptor families of zebrafish
-
•]) demonstrated the presence of Toll-like receptors (TLRs) in zebrafish and their homology to human TLRs, validating the use of zebrafish as a model to study innate immunity.
-
•]) demonstrated the presence of Toll-like receptors (TLRs) in zebrafish and their homology to human TLRs, validating the use of zebrafish as a model to study innate immunity.
-
(2004)
Mol Immunol
, vol.40
, pp. 773-783
-
-
Meijer, A.H.1
Gabby Krens, S.F.2
Medina Rodriguez, I.A.3
He, S.4
Bitter, W.5
Ewa Snaar-Jagalska, B.6
Spaink, H.P.7
-
29
-
-
0035892098
-
Morphologic and functional characterization of granulocytes and macrophages in embryonic and adult zebrafish
-
Lieschke G.J., Oates A.C., Crowhurst M.O., Ward A.C., and Layton J.E. Morphologic and functional characterization of granulocytes and macrophages in embryonic and adult zebrafish. Blood 98 (2001) 3087-3096
-
(2001)
Blood
, vol.98
, pp. 3087-3096
-
-
Lieschke, G.J.1
Oates, A.C.2
Crowhurst, M.O.3
Ward, A.C.4
Layton, J.E.5
-
30
-
-
0032861322
-
Ontogeny and behaviour of early macrophages in the zebrafish embryo
-
Herbomel P., Thisse B., and Thisse C. Ontogeny and behaviour of early macrophages in the zebrafish embryo. Development 126 (1999) 3735-3745
-
(1999)
Development
, vol.126
, pp. 3735-3745
-
-
Herbomel, P.1
Thisse, B.2
Thisse, C.3
-
31
-
-
0030891473
-
Characterization and expression of the recombination activating genes (rag1 and rag2) of zebrafish
-
Willett C.E., Cherry J.J., and Steiner L.A. Characterization and expression of the recombination activating genes (rag1 and rag2) of zebrafish. Immunogenetics 45 (1997) 394-404
-
(1997)
Immunogenetics
, vol.45
, pp. 394-404
-
-
Willett, C.E.1
Cherry, J.J.2
Steiner, L.A.3
-
32
-
-
14944348431
-
The immunoglobulin heavy-chain locus in zebrafish: identification and expression of a previously unknown isotype, immunoglobulin Z
-
This paper reports the identification of a new immunoglobin subtype in zebrafish which does not have a counterpart in humans, cautioning us against straightforward extrapolation of insights from zebrafish immune system studies to human immunity.
-
Danilova N., Bussmann J., Jekosch K., and Steiner L.A. The immunoglobulin heavy-chain locus in zebrafish: identification and expression of a previously unknown isotype, immunoglobulin Z. Nat Immunol 6 (2005) 295-302. This paper reports the identification of a new immunoglobin subtype in zebrafish which does not have a counterpart in humans, cautioning us against straightforward extrapolation of insights from zebrafish immune system studies to human immunity.
-
(2005)
Nat Immunol
, vol.6
, pp. 295-302
-
-
Danilova, N.1
Bussmann, J.2
Jekosch, K.3
Steiner, L.A.4
-
33
-
-
3242881303
-
The phylogenetic origins of the antigen-binding receptors and somatic diversification mechanisms
-
Cannon J.P., Haire R.N., Rast J.P., and Litman G.W. The phylogenetic origins of the antigen-binding receptors and somatic diversification mechanisms. Immunol Rev 200 (2004) 12-22
-
(2004)
Immunol Rev
, vol.200
, pp. 12-22
-
-
Cannon, J.P.1
Haire, R.N.2
Rast, J.P.3
Litman, G.W.4
-
34
-
-
25144507127
-
Evolution of the zebrafish model: from development to immunity and infectious disease
-
Phelps H.A., and Neely M.N. Evolution of the zebrafish model: from development to immunity and infectious disease. Zebrafish 2 (2005) 87-103
-
(2005)
Zebrafish
, vol.2
, pp. 87-103
-
-
Phelps, H.A.1
Neely, M.N.2
-
36
-
-
0034523554
-
Effects of infectious hematopoietic necrosis virus and infectious pancreatic necrosis virus infection on hematopoietic precursors of the zebrafish
-
LaPatra S.E., Barone L., Jones G.R., and Zon L.I. Effects of infectious hematopoietic necrosis virus and infectious pancreatic necrosis virus infection on hematopoietic precursors of the zebrafish. Blood Cells Mol Dis 26 (2000) 445-452
-
(2000)
Blood Cells Mol Dis
, vol.26
, pp. 445-452
-
-
LaPatra, S.E.1
Barone, L.2
Jones, G.R.3
Zon, L.I.4
-
37
-
-
0037362162
-
Characterization of rainbow trout and zebrafish eukaryotic initiation factor 2alpha and its response to endoplasmic reticulum stress and IPNV infection
-
Garner J.N., Joshi B., and Jagus R. Characterization of rainbow trout and zebrafish eukaryotic initiation factor 2alpha and its response to endoplasmic reticulum stress and IPNV infection. Dev Comp Immunol 27 (2003) 217-231
-
(2003)
Dev Comp Immunol
, vol.27
, pp. 217-231
-
-
Garner, J.N.1
Joshi, B.2
Jagus, R.3
-
38
-
-
0242721817
-
Susceptibility of zebrafish (Danio rerio) to a model pathogen, spring viremia of carp virus
-
Sanders G.E., Batts W.N., and Winton J.R. Susceptibility of zebrafish (Danio rerio) to a model pathogen, spring viremia of carp virus. Comp Med 53 (2003) 514-521
-
(2003)
Comp Med
, vol.53
, pp. 514-521
-
-
Sanders, G.E.1
Batts, W.N.2
Winton, J.R.3
-
39
-
-
13744250484
-
Characterization of snakehead rhabdovirus infection in zebrafish (Danio rerio)
-
Phelan P.E., Pressley M.E., Witten P.E., Mellon M.T., Blake S., and Kim C.H. Characterization of snakehead rhabdovirus infection in zebrafish (Danio rerio). J Virol 79 (2005) 1842-1852
-
(2005)
J Virol
, vol.79
, pp. 1842-1852
-
-
Phelan, P.E.1
Pressley, M.E.2
Witten, P.E.3
Mellon, M.T.4
Blake, S.5
Kim, C.H.6
-
40
-
-
33746039074
-
Skin infection caused by a new type of Mycobacterium in swimming pools
-
Linell F., and Norden A. Skin infection caused by a new type of Mycobacterium in swimming pools. Nord Med 47 (1952) 888-891
-
(1952)
Nord Med
, vol.47
, pp. 888-891
-
-
Linell, F.1
Norden, A.2
-
41
-
-
0031943169
-
Differentiation of Mycobacterium ulcerans, M. marinum, and M. haemophilum: mapping of their relationships to M. tuberculosis by fatty acid profile analysis, DNA-DNA hybridization, and 16S rRNA gene sequence analysis
-
Tonjum T., Welty D.B., Jantzen E., and Small P.L. Differentiation of Mycobacterium ulcerans, M. marinum, and M. haemophilum: mapping of their relationships to M. tuberculosis by fatty acid profile analysis, DNA-DNA hybridization, and 16S rRNA gene sequence analysis. J Clin Microbiol 36 (1998) 918-925
-
(1998)
J Clin Microbiol
, vol.36
, pp. 918-925
-
-
Tonjum, T.1
Welty, D.B.2
Jantzen, E.3
Small, P.L.4
-
42
-
-
0642333705
-
Zebrafish-Mycobacterium marinum model for mycobacterial pathogenesis
-
Prouty M.G., Correa N.E., Barker L.P., Jagadeeswaran P., and Klose K.E. Zebrafish-Mycobacterium marinum model for mycobacterial pathogenesis. FEMS Microbiol Lett 225 (2003) 177-182
-
(2003)
FEMS Microbiol Lett
, vol.225
, pp. 177-182
-
-
Prouty, M.G.1
Correa, N.E.2
Barker, L.P.3
Jagadeeswaran, P.4
Klose, K.E.5
-
43
-
-
7044286148
-
Mycobacterium marinum strains can be divided into two distinct types based on genetic diversity and virulence
-
van der Sar A.M., Abdallah A.M., Sparrius M., Reinders E., Vandenbroucke-Grauls C.M., and Bitter W. Mycobacterium marinum strains can be divided into two distinct types based on genetic diversity and virulence. Infect Immun 72 (2004) 6306-6312
-
(2004)
Infect Immun
, vol.72
, pp. 6306-6312
-
-
van der Sar, A.M.1
Abdallah, A.M.2
Sparrius, M.3
Reinders, E.4
Vandenbroucke-Grauls, C.M.5
Bitter, W.6
-
44
-
-
18744363879
-
Real-time visualization of mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos
-
First use of zebrafish for real-time analysis of a pathogen infecting a vertebrate host.
-
Davis J.M., Clay H., Lewis J.L., Ghori N., Herbomel P., and Ramakrishnan L. Real-time visualization of mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos. Immunity 17 (2002) 693-702. First use of zebrafish for real-time analysis of a pathogen infecting a vertebrate host.
-
(2002)
Immunity
, vol.17
, pp. 693-702
-
-
Davis, J.M.1
Clay, H.2
Lewis, J.L.3
Ghori, N.4
Herbomel, P.5
Ramakrishnan, L.6
-
45
-
-
17044418922
-
Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection
-
This report describes large-scale transcriptome analysis of gene expression changes on chronic mycobacterial-infection of zebrafish leading to new insights into mycobacterial pathogenesis.
-
Meijer A.H., Verbeek F.J., Salas-Vidal E., Corredor-Adamez M., Bussman J., van der Sar A.M., Otto G.W., Geisler R., and Spaink H.P. Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection. Mol Immunol 42 (2005) 1185-1203. This report describes large-scale transcriptome analysis of gene expression changes on chronic mycobacterial-infection of zebrafish leading to new insights into mycobacterial pathogenesis.
-
(2005)
Mol Immunol
, vol.42
, pp. 1185-1203
-
-
Meijer, A.H.1
Verbeek, F.J.2
Salas-Vidal, E.3
Corredor-Adamez, M.4
Bussman, J.5
van der Sar, A.M.6
Otto, G.W.7
Geisler, R.8
Spaink, H.P.9
-
46
-
-
0029821514
-
Comparative virulence between different strains of listeria in zebrafish (Brachydanio rerio) and mice
-
Menudier A., Rougier F.P., and Bosgiraud C. Comparative virulence between different strains of listeria in zebrafish (Brachydanio rerio) and mice. Pathol Biol (Paris) 44 (1996) 783-789
-
(1996)
Pathol Biol (Paris)
, vol.44
, pp. 783-789
-
-
Menudier, A.1
Rougier, F.P.2
Bosgiraud, C.3
-
47
-
-
0036081383
-
Streptococcus-zebrafish model of bacterial pathogenesis
-
Neely M.N., Pfeifer J.D., and Caparon M. Streptococcus-zebrafish model of bacterial pathogenesis. Infect Immun 70 (2002) 3904-3914
-
(2002)
Infect Immun
, vol.70
, pp. 3904-3914
-
-
Neely, M.N.1
Pfeifer, J.D.2
Caparon, M.3
-
48
-
-
0034999527
-
A functional genomic analysis of type 3 Streptococcus pneumoniae virulence
-
Lau G.W., Haataja S., Lonetto M., Kensit S.E., Marra A., Bryant A.P., McDevitt D., Morrison D.A., and Holden D.W. A functional genomic analysis of type 3 Streptococcus pneumoniae virulence. Mol Microbiol 40 (2001) 555-571
-
(2001)
Mol Microbiol
, vol.40
, pp. 555-571
-
-
Lau, G.W.1
Haataja, S.2
Lonetto, M.3
Kensit, S.E.4
Marra, A.5
Bryant, A.P.6
McDevitt, D.7
Morrison, D.A.8
Holden, D.W.9
-
49
-
-
12844276013
-
Large-scale screen highlights the importance of capsule for virulence in the zoonotic pathogen Streptococcus iniae
-
First large-scale attempt to identify host genes involved in zebrafish infection by Streptococcus iniae. This report provides proof of principle for use of zebrafish infection models in identification of host pathogenesis factors.
-
Miller J.D., and Neely M.N. Large-scale screen highlights the importance of capsule for virulence in the zoonotic pathogen Streptococcus iniae. Infect Immun 73 (2005) 921-934. First large-scale attempt to identify host genes involved in zebrafish infection by Streptococcus iniae. This report provides proof of principle for use of zebrafish infection models in identification of host pathogenesis factors.
-
(2005)
Infect Immun
, vol.73
, pp. 921-934
-
-
Miller, J.D.1
Neely, M.N.2
-
50
-
-
0346251029
-
Contribution of glutathione peroxidase to the virulence of Streptococcus pyogenes
-
Brenot A., King K.Y., Janowiak B., Griffith O., and Caparon M.G. Contribution of glutathione peroxidase to the virulence of Streptococcus pyogenes. Infect Immun 72 (2004) 408-413
-
(2004)
Infect Immun
, vol.72
, pp. 408-413
-
-
Brenot, A.1
King, K.Y.2
Janowiak, B.3
Griffith, O.4
Caparon, M.G.5
-
51
-
-
0034700166
-
Small molecule developmental screens reveal the logic and timing of vertebrate development
-
Peterson R.T., Link B.A., Dowling J.E., and Schreiber S.L. Small molecule developmental screens reveal the logic and timing of vertebrate development. Proc Natl Acad Sci USA 97 (2000) 12965-12969
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 12965-12969
-
-
Peterson, R.T.1
Link, B.A.2
Dowling, J.E.3
Schreiber, S.L.4
-
52
-
-
0037009971
-
A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening
-
Moon H.S., Jacobson E.M., Khersonsky S.M., Luzung M.R., Walsh D.P., Xiong W., Lee J.W., Parikh P.B., Lam J.C., Kang T.W., et al. A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening. J Am Chem Soc 124 (2002) 11608-11609
-
(2002)
J Am Chem Soc
, vol.124
, pp. 11608-11609
-
-
Moon, H.S.1
Jacobson, E.M.2
Khersonsky, S.M.3
Luzung, M.R.4
Walsh, D.P.5
Xiong, W.6
Lee, J.W.7
Parikh, P.B.8
Lam, J.C.9
Kang, T.W.10
-
53
-
-
0141732260
-
Facilitated forward chemical genetics using a tagged triazine library and zebrafish embryo screening
-
Khersonsky S.M., Jung D.W., Kang T.W., Walsh D.P., Moon H.S., Jo H., Jacobson E.M., Shetty V., Neubert T.A., and Chang Y.T. Facilitated forward chemical genetics using a tagged triazine library and zebrafish embryo screening. J Am Chem Soc 125 (2003) 11804-11805
-
(2003)
J Am Chem Soc
, vol.125
, pp. 11804-11805
-
-
Khersonsky, S.M.1
Jung, D.W.2
Kang, T.W.3
Walsh, D.P.4
Moon, H.S.5
Jo, H.6
Jacobson, E.M.7
Shetty, V.8
Neubert, T.A.9
Chang, Y.T.10
-
54
-
-
2342454415
-
Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation
-
Peterson R.T., Shaw S.Y., Peterson T.A., Milan D.J., Zhong T.P., Schreiber S.L., MacRae C.A., and Fishman M.C. Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation. Nat Biotechnol 22 (2004) 595-599
-
(2004)
Nat Biotechnol
, vol.22
, pp. 595-599
-
-
Peterson, R.T.1
Shaw, S.Y.2
Peterson, T.A.3
Milan, D.J.4
Zhong, T.P.5
Schreiber, S.L.6
MacRae, C.A.7
Fishman, M.C.8
-
55
-
-
33644788489
-
Small molecules that delay S phase suppress a zebrafish bmyb mutant
-
Stern H.M., Murphey R.D., Shepard J.L., Amatruda J.F., Straub C.T., Pfaff K.L., Weber G., Tallarico J.A., King R.W., and Zon L.I. Small molecules that delay S phase suppress a zebrafish bmyb mutant. Nat Chem Biol 1 (2005) 366-370
-
(2005)
Nat Chem Biol
, vol.1
, pp. 366-370
-
-
Stern, H.M.1
Murphey, R.D.2
Shepard, J.L.3
Amatruda, J.F.4
Straub, C.T.5
Pfaff, K.L.6
Weber, G.7
Tallarico, J.A.8
King, R.W.9
Zon, L.I.10
-
56
-
-
26944441684
-
Zebrafish as a model vertebrate for investigating chemical toxicity
-
Hill A.J., Teraoka H., Heideman W., and Peterson R.E. Zebrafish as a model vertebrate for investigating chemical toxicity. Toxicol Sci 86 (2005) 6-19
-
(2005)
Toxicol Sci
, vol.86
, pp. 6-19
-
-
Hill, A.J.1
Teraoka, H.2
Heideman, W.3
Peterson, R.E.4
-
57
-
-
12144273121
-
In vivo drug discovery in the zebrafish
-
Zon L.I., and Peterson R.T. In vivo drug discovery in the zebrafish. Nat Rev Drug Discov 4 (2005) 35-44
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 35-44
-
-
Zon, L.I.1
Peterson, R.T.2
-
58
-
-
0037257973
-
The state of the art of the zebrafish model for toxicology and toxicologic pathology research-advantages and current limitations
-
Spitsbergen J.M., and Kent M.L. The state of the art of the zebrafish model for toxicology and toxicologic pathology research-advantages and current limitations. Toxicol Pathol 31 (2003) 62-87
-
(2003)
Toxicol Pathol
, vol.31
, pp. 62-87
-
-
Spitsbergen, J.M.1
Kent, M.L.2
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