The phylogenetic origins of the antigen-binding receptors and somatic diversification mechanisms

Immunological Reviews

Volumn 200, Issue , 2004, Pages 12-22

  Cannon, John P ^a,b   Haire, Robert N ^c   Rast, Jonathan P ^d   Litman, Gary W ^a,b,c  

^a JOHNS HOPKINS ALL CHILDREN S HOSPITAL   (United States)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d SUNNYBROOK RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CHITIN; COMPLEMENTARY DNA; DEAMINASE; DNA; IMMUNOGLOBULIN; IMMUNOGLOBULIN M; LYMPHOCYTE ANTIGEN RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; RAG1 PROTEIN; RAG2 PROTEIN; T LYMPHOCYTE RECEPTOR;

ANTIBODY AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL LINEAGE; ECHINODERM; GENE CLUSTER; GENE CONVERSION; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENE LOCUS; GENE REARRANGEMENT; GENE SEQUENCE; GENE SWITCHING; GENETIC ANALYSIS; GENETIC RECOMBINATION; IMMUNE SYSTEM; IMMUNITY; INVERTEBRATE; LYMPHOCYTE; MOLECULAR RECOGNITION; MULTIGENE FAMILY; NONHUMAN; PHYLOGENY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; REVIEW; SEQUENCE HOMOLOGY; SOMATIC HYPERMUTATION; SOMATIC MUTATION; VERTEBRATE;

ANIMALS; ANTIBODY DIVERSITY; ECHINODERMATA; EVOLUTION, MOLECULAR; GENES, IMMUNOGLOBULIN; HUMANS; MUTATION; PHYLOGENY; RECEPTORS, ANTIGEN, T-CELL; VDJ RECOMBINASES; VERTEBRATES;

EID: 3242881303     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0105-2896.2004.00166.x     Document Type: Review

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