Biochemical parameters in autistic children

Developmental Brain Dysfunction

Volumn 10, Issue 1, 1997, Pages 40-43

  Waring, R H ^a   Ngong, J M ^b   Klovrza, L ^b   Green, S ^b   Sharp, H ^b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b NONE

Author keywords

Autism; Paracetamol (acetaminophen); Phenolsulphotransferase; Sulphate; Sulphation

Indexed keywords

PARACETAMOL; SULFATE;

ARTICLE; AUTISM; CHILD; DEVELOPMENTAL DISORDER; DRUG BLOOD LEVEL; DRUG EXCRETION; HUMAN; HYPERACTIVITY; MENTAL DEFICIENCY; MIGRAINE; NEUROLOGIC DISEASE; SEROLOGY; SULFATION;

EID: 0031052835     PISSN: 10195815     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Cohen D, Caparulo BK, Shaywitz BA, Bower MB: Dopamine and serotonin metabolism in neuropsychiatrically disturbed children. Arch Gen Psychiatry 1977;42:780-783.
2. Weinshilboum R: Sulfotranferase pharmacogenetics; in Kalow W (ed): Pharmacogenetics of Drug Metabolism. Oxford, Pergamon Press, 1992, pp 227-242.
3. 3H-imipramine binding and sulphotransferase activity in primary headache. Cephalalgia 1994;14:210-214.
4. Steventon GB, Heafield MTE, Waring RH, Williams AC, Sturman S, Green M: Metabolism of low-dose paracetamol in patients with chronic neurological disease. Xenobiotica 1990;20: 117-122.
5. Heafield MTE, Fearn S, Steventon GB, Waring RH, Williams AC: Plasma cysteine and sulphate levels in motor neurone, Parkinson's and Alzheimer's disease. Neurosci Lett 1990;110:216-220.
6. Bradley H, Waring RH, Emery P, Arthur V: Metabolism of low-dose paracetamol in patients with rheumatoid arthritis. Xenobiotica 1991;21: 689-693.
7. Pilkington AE, Waring RH: The determination of inorganic sulphate levels in biological fluids. Med Sci Res 1989;16:35-36.
8. Bradford MM: A rapid and sensitive method for the quantification of microgram quantities of protein utilising the principles of protein-dye binding. Anal Biochem 1976;72:248-254.
9. Anderson RJ, Weinshilboum RM: Phenolsulphotransferase in human tissue: Radiochemical enzymatic assay and biochemical propeaies. Clin Chim Acta 1980;103:79-90.
10. Alam ZI, Waring RH, Williams AC, Coombes N: Migraine in family studies. Proc 6th North Am ISSX Meet, Raleigh, 1994, vol 6, p 249.
11. Levy G: Sulphate conjugation in drug metabolism: Role of inorganic sulphate. Fed Proc 1986;45: 2235-2240.
12. Kuchel O, Buu NT, Racz K, de Lean A, Servi O, Kyncl J: Role of sulfate conjugation of catecholamines in blood pressure regulation. Fed Proc 1986;45:2254-2259.
13. Barthélémy C, Bruneau N, Cottet-Eynard JM, Domenech-Jouve J, Garreau B, Lelord G, Muh JP, Peyrin L: Urinary free and conjugated catecholamines and metabolites in autistic children. J Autism Dev Disord 1988;18:583-591.
14. Ngong JM: Metabolic Patterns in Clinical Conditions (PhD thesis). University of Birmingham, 1993.
15. Bonham-Carter SM, Glover V, Sandler M, Filman PK, Bridges PK: Human platelet PST: Separate control of two forms and activity range in depressive illness. Clin Chim Acta 1981;117: 333-337.
16. Gibb C, Glover V, Sandler M: In vitro inhibition of phenolsulphotransferase by food and drink constituents. Biochem Pharmacol 1987;36:2325-2930.
17. Murch SH, MacDonald TT, Walker-Smith JH, Levin M, Lionetti P, Klein NJ: Disruption of sulphated glycoamino glycans in intestinal inflammation. Lancet 1993;i:711-714.
18. Reichelt KL: Perspectives in autism; in Linfoot G, Saveray D, Shattock P (eds): Biological Perspectives in Autism. Sunderland, University Press, 1993, pp 65-82.