Phosphorylation of rat brain mitochondrial voltage-dependent anion as a potential tool to control leakage of cytochrome c

Journal of Neurochemistry

Volumn 98, Issue 3, 2006, Pages 670-676

  Banerjee, Jyotirmoy ^a   Ghosh, Subhendu ^b  

^a UNIVERSITY OF DELHI   (India)

^b UNIVERSITY OF HYDERABAD   (India)

Author keywords

Bax; Bilayer electrophysiology; Cell death; Phosphorylation; Protein kinase A; Voltage dependent anion channel

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE A; CYTOCHROME C; MEMBRANE PROTEIN; PROTEIN BAX; PROTEIN BID; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL;

ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; CHANNEL GATING; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ENZYME RELEASE; ION CONDUCTANCE; LIPID BILAYER; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT;

ANIMALS; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BRAIN; CELL DEATH; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOCHROMES C; LIPID BILAYERS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; PHOSPHORYLATION; RATS; TIME FACTORS; VOLTAGE-DEPENDENT ANION CHANNELS;

EID: 33745920512     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03853.x     Document Type: Article

References (36)

1. Adams J. M. and Cory S. (2001) Life-or-death decisions by the Bcl-2 protein family. Trends Biochem. Sci. 26, 61-66.
2. Banerjee J. and Ghosh S. (2004a) Bax increases the pore size of rat brain mitochondrial VDAC in the presence of tBid. Biochem. Biophys. Res. Commn. 323, 310-314.
3. Banerjee J. and Ghosh S. (2004b) Interaction of mitochondrial voltage-dependent anion channel from rat brain with plasminogen protein leads to partial closure of the channel. Biochim. Biophys. Acta 1663, 6-8.
4. Banerjee J. and Ghosh S. (2005) Investigating interaction of ligands with voltage dependent anion channel through noise analyses. Arch. Biochem. Biophys. 435, 369-371.
5. Bera A. K. and Ghosh S. (2001) Dual mode of gating of voltage-dependent anion channel as revealed by phosphorylation. J. Struc. Biol. 135, 67-72.
6. Bera A. K., Ghosh S. and Das S. (1995) Mitochondrial VDAC can be phosphorylated by cyclic AMP-dependent protein kinase. Biochim. Biophys. Res. Commun. 209, 213-217.
7. Budihardjo I., Oliver H., Lutter M., Luo X. and Wang X. (1999) Biochemical pathways of caspase activation during apoptosis. Annu. Rev. Cell Dev. Biol. 15, 269-290.
8. Catterall W. A. (1988) Structure and function of voltage-sensitive ion channels. Science 242, 50-61.
9. Clayton R., Clark J. B. and Sharpe M. (2005) Cytochrome c release from rat brain mitochondria is proportional to the mitochondrial functional deficit: implications for apoptosis and neurodegenerative disease. J. Neurochem. 92, 840-849.
10. Cohen P. (1988) Protein phosphorylation and hormone action. Proc. R. Soc. Lond., B 234, 115-144.
11. Cohen P. (1992) Signal integration at the level of protein kinases, protein phosphatases and their substrates. Trends Biochem. Sci. 17, 408-413.
12. De Pinto V., Tommasino M., Benz R. and Palmieri F. (1985) The 35 kDa DCCD-binding protein from pig heart mitochondria is the mitochondrial porin. Biochim. Biophys. Acta. 813, 230-242.
13. De Pinto V., Prezioso G. and Palmieri F. (1987) A simple and rapid method for purification of the mitochondrial porin from mammalian tissues. Biochim. Biophys. Acta. 905, 499-502.
14. Du C. Y., Fang M., Li Y. C., Li L. and Wang X. D. (2000) Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102, 33-42.
15. Gincel D. and Shoshan-Barmatz V. (2004) Glutamate interacts with VDAC and modulates opening of the mitochondrial permeability transition pore. J. Bioenerg. Biomembr. 36, 179-186.
16. van der Heiden M. G., Li X. X., Gotteleib E., Hill R. B., Thompson C. B. and Colombini M. (2001) Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane. J. Biol. Chem. 276, 19414-19419.
17. Hemmings H. C., Nairn A. C., McGuinness T. L., Huganir R. L. and Greengard P. (1991) Role of protein phosphorylation in neuronal signal transduction. FASEB J. 3, 1582-1592.
18. Jiang X. and Wang X. D. (2004) Cytochrome c-mediated apoptosis. Annu. Rev. Biochem. 73, 87-106.
19. Krippner A., Matsuno-Yagi A., Gottlieb R. A. and Baboir B. M. (1996) Loss of function of cytochrome c in Jurkat cells undergoing fasmediated apoptosis. J. Biol. Chem. 271, 21 629-21 636.
20. Le Mellay V., Troppmair J., Benz R. and Rapp U. R. (2002) Negative regulation of mitochondrial VDAC channels by C-Raf kinase. BMC Cell Biol. 3, 14-25.
21. Levitan I. B. (1988) Modulation of ion channels in neurons and other cells. Annu. Rev. Neurosci. 11, 119-136.
22. Levitan I. B. (1994) Modulation of ion channels by protein phosphorylation and dephosphorylation. Annu. Rev. Physiol. 56, 193-212.
23. Li P., Nijhwan D., Budiharjo I., Srinivasula S. M., Ahmad M., Alnemeri E. S. and Wang X. (1997) Cytochrome c and dATP dependent formation of Apaf-1/Caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-489.
24. Li L. Y., Luo L. and Wang X. D. (2001) Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 412, 95-99.
25. MacGibbon G. A., Lawlor P. A., Sirimanne E. S. et al. (1997) Bax expression in mammalian neurons undergoing apoptosis, and in Alzheimer's disease hippocampus. Brain Res. 750, 223-234.
26. Roos N., Benz R. and Brdiczka D. (1982) Identification and characterization of pore-forming protein in the outer membrane of rat liver mitochondria. Biochim. Biophys. Acta 686, 204-214.
27. Rostovtseva T. K., Antonsson B., Suzuki M., Youle R. J., Colombini M. and Bezrukov S. M. (2004) Bid but not Bax regulates VDAC channels. J.Biol. Chem. 279, 13 575-13 583.
28. Rostovtseva T. K., Tan W. and Colombini M. (2005) On the role of VDAC in apoptosis: fact and fiction. J. Bioenerg. Biomembr. 37, 129-142.
29. Roucou X., Rostovtseva T. K., Montessuit S., Martinou J. C. and Antonsson B. (2002) Bid induces cytochrome c-impermeable Bax channels in liposomes. Biochem. J. 363, 547-552.
30. Shimizu S., Narita M. and Tsujimoto Y. (1999) Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 399, 483-487.
31. Shimizu S., Ide T., Yanagida T. and Tsujimoto Y. (2000) Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c. J. Biol. Chem. 275, 12 321-12 325.
32. Su J. H., Deng G. and Cotman C. W. (1997) Bax protein expression is increased in Alzheimer's brain: correlations with DNA damage, Bcl-2 expression, and brain pathology. J. Neuropathol. Exp. Neurol. 56, 86-93.
33. Susin S. A., Lorenzo H. K., Zamzami N. et al. (1999) Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397, 441-446.
34. Verhagen A. M., Ekert P. G., Pakusch M., Silke J., Connolly L. M., Reid G. E., Moritz R. L., Simpson R. J. and Vaux D. L. (2000) Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 102, 43-53.
35. Vila M., Jackson-Lewis V., Vukosavic S., Djaldetti R., Liberatore G., Offen D., Korsmeyer S. J. and Przedborski S. (2001) Bax ablation prevents dopaminergic neuro-degeneration in the 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine mouse model of Parkinson's disease. Proc. Natl Acad. Sci. USA 98, 2837-2842.
36. Zizi M., Forte M., Blachly-Dyson E. and Colombini M. (1994) NADH regulates the gating of VDAC, the mitochondrial outer membrane channel. J. Biol. Chem. 269, 1614-1616.