-
1
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
-
Altschul, S. F., T. L. Madden, A. A. Schaffer, J. Zhang, Z. Zhang, W. Miller, and D. J. Lipman. 1997. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25:3389-3402.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schaffer, A.A.3
Zhang, J.4
Zhang, Z.5
Miller, W.6
Lipman, D.J.7
-
2
-
-
14744301187
-
Structure-activity relationship analysis and therapeutic potential of peptide deformylase inhibitors
-
Boularot, A., C. Giglione, I. Artaud, and T. Meinnel. 2004. Structure-activity relationship analysis and therapeutic potential of peptide deformylase inhibitors. Curr. Opin. Investig. Drugs 5:809-822.
-
(2004)
Curr. Opin. Investig. Drugs
, vol.5
, pp. 809-822
-
-
Boularot, A.1
Giglione, C.2
Artaud, I.3
Meinnel, T.4
-
3
-
-
0018255173
-
Classification of the Legionnaires' disease bacterium: An interim report
-
Brenner, D. J., A. Steigerwalt, J. E. Weaver, J. E. McDade, J. C. Feeley, and M. Mandel. 1978. Classification of the Legionnaires' disease bacterium: an interim report. Curr. Microbiol. 1:71-75.
-
(1978)
Curr. Microbiol.
, vol.1
, pp. 71-75
-
-
Brenner, D.J.1
Steigerwalt, A.2
Weaver, J.E.3
McDade, J.E.4
Feeley, J.C.5
Mandel, M.6
-
4
-
-
10044263696
-
Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity
-
Cazalet, C., C. Rusniok, H. Bruggemann, N. Zidane, A. Magnier, L. Ma, M. Tichit, S. Jarraud, C. Bouchier, F. Vandenesch, F. Kunst, J. Etienne, P. Glaser, and C. Buchrieser. 2004. Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity. Nat. Genet. 36:1165-1173.
-
(2004)
Nat. Genet.
, vol.36
, pp. 1165-1173
-
-
Cazalet, C.1
Rusniok, C.2
Bruggemann, H.3
Zidane, N.4
Magnier, A.5
Ma, L.6
Tichit, M.7
Jarraud, S.8
Bouchier, C.9
Vandenesch, F.10
Kunst, F.11
Etienne, J.12
Glaser, P.13
Buchrieser, C.14
-
5
-
-
0037336363
-
Characterization of a novel fucose-regulated promoter (Pf-csK) suitable for gene essentiality and antibacterial mode-of-action studies in Streptococcus pneumoniae
-
Chan, P. F., K. M. O'Dwyer, L. M. Palmer, J. D. Ambrad, K. A. Ingraham, C. So, M. A. Lonetto, S. Biswas, M. Rosenberg, D. J. Holmes, and M. Zalacain. 2003. Characterization of a novel fucose-regulated promoter (Pf-csK) suitable for gene essentiality and antibacterial mode-of-action studies in Streptococcus pneumoniae. J. Bacteriol. 185:2051-2058.
-
(2003)
J. Bacteriol.
, vol.185
, pp. 2051-2058
-
-
Chan, P.F.1
O'Dwyer, K.M.2
Palmer, L.M.3
Ambrad, J.D.4
Ingraham, K.A.5
So, C.6
Lonetto, M.A.7
Biswas, S.8
Rosenberg, M.9
Holmes, D.J.10
Zalacain, M.11
-
6
-
-
0034673093
-
Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor
-
Chen, D. Z., D. V. Patel, C. J. Hackbarth, W. Wang, G. Dreyer, D. C. Young, P. S. Margolis, C. Wu, Z. J. Ni, J. Trias, R. J. White, and Z. Yuan. 2000. Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor. Biochemistry 39:1256-1262.
-
(2000)
Biochemistry
, vol.39
, pp. 1256-1262
-
-
Chen, D.Z.1
Patel, D.V.2
Hackbarth, C.J.3
Wang, W.4
Dreyer, G.5
Young, D.C.6
Margolis, P.S.7
Wu, C.8
Ni, Z.J.9
Trias, J.10
White, R.J.11
Yuan, Z.12
-
7
-
-
4644276577
-
The genomic sequence of the accidental pathogen Legionella pneumophila
-
Chien, M., I. Morozova, S. Shi, H. Sheng, J. Chen, S. M. Gomez, G. Asamani, K. Hill, J. Nuara, M. Feder, J. Rineer, J. J. Greenberg, V. Steshenko, S. H. Park, B. Zhao, E. Teplitskaya, J. R. Edwards, S. Pampou, A. Georghiou, I. C. Chou, W. Iannuccilli, M. E. Ulz, D. H. Kim, A. Geringer-Sameth, C. Goldsherry, P. Morozov, S. G. Fischer, G. Segal, X. Qu, A. Rzhetsky, P. Zhang, E. Cayanis, P. J. De Jong, J. Ju, S. Kalachikov, H. A. Shuman, and J. J. Russo. 2004. The genomic sequence of the accidental pathogen Legionella pneumophila. Science 305:1966-1968.
-
(2004)
Science
, vol.305
, pp. 1966-1968
-
-
Chien, M.1
Morozova, I.2
Shi, S.3
Sheng, H.4
Chen, J.5
Gomez, S.M.6
Asamani, G.7
Hill, K.8
Nuara, J.9
Feder, M.10
Rineer, J.11
Greenberg, J.J.12
Steshenko, V.13
Park, S.H.14
Zhao, B.15
Teplitskaya, E.16
Edwards, J.R.17
Pampou, S.18
Georghiou, A.19
Chou, I.C.20
Iannuccilli, W.21
Ulz, M.E.22
Kim, D.H.23
Geringer-Sameth, A.24
Goldsherry, C.25
Morozov, P.26
Fischer, S.G.27
Segal, G.28
Qu, X.29
Rzhetsky, A.30
Zhang, P.31
Cayanis, E.32
De Jong, P.J.33
Ju, J.34
Kalachikov, S.35
Shuman, H.A.36
Russo, J.J.37
more..
-
8
-
-
0035143273
-
Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor
-
Clements, J. M., R. P. Beckett, A. Brown, G. Catlin, M. Lobell, S. Palan, W. Thomas, M. Whittaker, S. Wood, S. Salama, P. J. Baker, H. F. Rodgers, V. Barynin, D. W. Rice, and M. G. Hunter. 2001. Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor. Antimicrob. Agents Chemother. 45:563-570.
-
(2001)
Antimicrob. Agents Chemother.
, vol.45
, pp. 563-570
-
-
Clements, J.M.1
Beckett, R.P.2
Brown, A.3
Catlin, G.4
Lobell, M.5
Palan, S.6
Thomas, W.7
Whittaker, M.8
Wood, S.9
Salama, S.10
Baker, P.J.11
Rodgers, H.F.12
Barynin, V.13
Rice, D.W.14
Hunter, M.G.15
-
9
-
-
0021324319
-
Legionnaires' disease. A review
-
Edelstein, P. H., and R. D. Meyer. 1984. Legionnaires' disease. A review. Chest 85:114-120.
-
(1984)
Chest
, vol.85
, pp. 114-120
-
-
Edelstein, P.H.1
Meyer, R.D.2
-
11
-
-
0036314980
-
Legionella and Legionnaires' disease: 25 Years of investigation
-
Fields, B. S., R. F. Benson, and R. E. Besser. 2002. Legionella and Legionnaires' disease: 25 years of investigation. Clin. Microbiol. Rev. 15:506-526.
-
(2002)
Clin. Microbiol. Rev.
, vol.15
, pp. 506-526
-
-
Fields, B.S.1
Benson, R.F.2
Besser, R.E.3
-
12
-
-
16244411296
-
Comparative antimicrobial characterization of LBM415 (NVP PDF-713), a new peptide deformylase inhibitor of clinical importance
-
Fritsche, T. R., H. S. Sader, R. Cleeland, and R. N. Jones. 2005. Comparative antimicrobial characterization of LBM415 (NVP PDF-713), a new peptide deformylase inhibitor of clinical importance. Antimicrob. Agents Chemother. 49:1468-1476.
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 1468-1476
-
-
Fritsche, T.R.1
Sader, H.S.2
Cleeland, R.3
Jones, R.N.4
-
13
-
-
0035543404
-
Organellar peptide deformylases: Universality of the N-terminal methionine cleavage mechanism
-
Giglione, C., and T. Meinnel. 2001. Organellar peptide deformylases: universality of the N-terminal methionine cleavage mechanism. Trends Plant Sci. 6:566-572.
-
(2001)
Trends Plant Sci.
, vol.6
, pp. 566-572
-
-
Giglione, C.1
Meinnel, T.2
-
14
-
-
0033936704
-
Peptide deformylase as a target for new generation, broad spectrum antimicrobial agents
-
Giglione, C., M. Pierre, and T. Meinnel. 2000. Peptide deformylase as a target for new generation, broad spectrum antimicrobial agents. Mol. Microbiol. 36:1197-1205.
-
(2000)
Mol. Microbiol.
, vol.36
, pp. 1197-1205
-
-
Giglione, C.1
Pierre, M.2
Meinnel, T.3
-
15
-
-
0035573721
-
Inhibition and structure-activity studies of methionine hydroxamic acid derivatives with bacterial peptide deformylase
-
Grant, S. K., B. G. Green, and J. W. Kozarich. 2001. Inhibition and structure-activity studies of methionine hydroxamic acid derivatives with bacterial peptide deformylase. Bioorg. Chem. 29:211-222.
-
(2001)
Bioorg. Chem.
, vol.29
, pp. 211-222
-
-
Grant, S.K.1
Green, B.G.2
Kozarich, J.W.3
-
16
-
-
0032546490
-
Isolation and crystallization of functionally competent Escherichia coli peptide deformylase forms containing either iron or nickel in the active site
-
Groche, D., A. Becker, I. Schlichting, W. Kabsch, S. Schultz, and A. F. Wagner. 1998. Isolation and crystallization of functionally competent Escherichia coli peptide deformylase forms containing either iron or nickel in the active site. Biochem. Biophys. Res. Commun. 246:342-346.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.246
, pp. 342-346
-
-
Groche, D.1
Becker, A.2
Schlichting, I.3
Kabsch, W.4
Schultz, S.5
Wagner, A.F.6
-
17
-
-
12144286857
-
Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor
-
Gross, M., J. Clements, R. P. Beckett, W. Thomas, S. Taylor, D. Lofland, S. Ramanathan-Girish, M. Garcia, S. Difuntorum, U. Hoch, H. Chen, and K. W. Johnson. 2004. Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor. J. Antimicrob. Chemother. 53:487-493.
-
(2004)
J. Antimicrob. Chemother.
, vol.53
, pp. 487-493
-
-
Gross, M.1
Clements, J.2
Beckett, R.P.3
Thomas, W.4
Taylor, S.5
Lofland, D.6
Ramanathan-Girish, S.7
Garcia, M.8
Difuntorum, S.9
Hoch, U.10
Chen, H.11
Johnson, K.W.12
-
18
-
-
0036077847
-
The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: A platform for the structure-based design of antibacterial agents
-
Guilloteau, J. P., M. Mathieu, C. Giglione, V. Blanc, A. Dupuy, M. Chevrier, P. Gil, A. Famechon, T. Meinnel, and V. Mikol. 2002. The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents. J. Mol. Biol. 320:951-962.
-
(2002)
J. Mol. Biol.
, vol.320
, pp. 951-962
-
-
Guilloteau, J.P.1
Mathieu, M.2
Giglione, C.3
Blanc, V.4
Dupuy, A.5
Chevrier, M.6
Gil, P.7
Famechon, A.8
Meinnel, T.9
Mikol, V.10
-
19
-
-
2342654040
-
Antimicrobial spectrum and activity of NVP PDF-713, a novel peptide deformylase inhibitor, tested against 1,837 recent Gram-positive clinical isolates
-
Jones, R. N., T. R. Fritsche, and H. S. Sader. 2004. Antimicrobial spectrum and activity of NVP PDF-713, a novel peptide deformylase inhibitor, tested against 1,837 recent Gram-positive clinical isolates. Diagn. Microbiol. Infect. Dis. 49:63-65.
-
(2004)
Diagn. Microbiol. Infect. Dis.
, vol.49
, pp. 63-65
-
-
Jones, R.N.1
Fritsche, T.R.2
Sader, H.S.3
-
20
-
-
0031025121
-
Formate dehydrogenase-coupled spectrophotometric assay of peptide deformylase
-
Lazennec, C., and T. Meinnel. 1997. Formate dehydrogenase-coupled spectrophotometric assay of peptide deformylase. Anal. Biochem. 244:180-182.
-
(1997)
Anal. Biochem.
, vol.244
, pp. 180-182
-
-
Lazennec, C.1
Meinnel, T.2
-
21
-
-
1642373345
-
In vitro antibacterial activity of the peptide deformylase inhibitor BB-83698
-
Lofland, D., S. Difuntorum, A. Waller, J. M. Clements, M. K. Weaver, J. A. Karlowsky, and K. Johnson. 2004. In vitro antibacterial activity of the peptide deformylase inhibitor BB-83698. J. Antimicrob. Chemother. 53:664-668.
-
(2004)
J. Antimicrob. Chemother.
, vol.53
, pp. 664-668
-
-
Lofland, D.1
Difuntorum, S.2
Waller, A.3
Clements, J.M.4
Weaver, M.K.5
Karlowsky, J.A.6
Johnson, K.7
-
22
-
-
0033919993
-
Peptide deformylase in Staphylococcus aureus: Resistance to inhibition is mediated by mutations in the formyltransferase gene
-
Margolis, P. S., C. J. Hackbarth, D. C. Young, W. Wang, D. Chen, Z. Yuan, R. White, and J. Trias. 2000. Peptide deformylase in Staphylococcus aureus: resistance to inhibition is mediated by mutations in the formyltransferase gene. Antimicrob. Agents Chemother. 44:1825-1831.
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, pp. 1825-1831
-
-
Margolis, P.S.1
Hackbarth, C.J.2
Young, D.C.3
Wang, W.4
Chen, D.5
Yuan, Z.6
White, R.7
Trias, J.8
-
23
-
-
0031552348
-
Structure-function relationships within the peptide deformylase family. Evidence for a conserved architecture of the active site involving three conserved motifs and a metal ion
-
Meinnel, T., C. Lazennec, S. Villoing, and S. Blanquet. 1997. Structure-function relationships within the peptide deformylase family. Evidence for a conserved architecture of the active site involving three conserved motifs and a metal ion. J. Mol. Biol. 4:749-761.
-
(1997)
J. Mol. Biol.
, vol.4
, pp. 749-761
-
-
Meinnel, T.1
Lazennec, C.2
Villoing, S.3
Blanquet, S.4
-
24
-
-
3142512687
-
Differentiate to thrive: Lessons from the Legionella pneumophila life cycle
-
Molofsky, A. B., and M. S. Swanson. 2004. Differentiate to thrive: lessons from the Legionella pneumophila life cycle. Mol. Microbiol. 53:29-40.
-
(2004)
Mol. Microbiol.
, vol.53
, pp. 29-40
-
-
Molofsky, A.B.1
Swanson, M.S.2
-
25
-
-
0042473206
-
Characterization of a human peptide deformylase: Implications for antibacterial drug design
-
Nguyen, K. T., X. Hu, C. Colton, R. Chakrabarti, M. X. Zhu, and D. Pei. 2003. Characterization of a human peptide deformylase: implications for antibacterial drug design. Biochemistry 42:9952-9958.
-
(2003)
Biochemistry
, vol.42
, pp. 9952-9958
-
-
Nguyen, K.T.1
Hu, X.2
Colton, C.3
Chakrabarti, R.4
Zhu, M.X.5
Pei, D.6
-
26
-
-
1942421679
-
Slow-binding inhibition of peptide deformylase by cyclic peptidomimetics as revealed by a new spectrophotometric assay
-
Nguyen, K. T., X. Hu, and D. Pei. 2004. Slow-binding inhibition of peptide deformylase by cyclic peptidomimetics as revealed by a new spectrophotometric assay. Bioorg. Chem. 32:178-191.
-
(2004)
Bioorg. Chem.
, vol.32
, pp. 178-191
-
-
Nguyen, K.T.1
Hu, X.2
Pei, D.3
-
27
-
-
0030203863
-
Tree View: An application to display phylogenetic trees on personal computers
-
Page, R. D. 1996. Tree View: an application to display phylogenetic trees on personal computers. Comput. Appl. Biosci. 12:357-358.
-
(1996)
Comput. Appl. Biosci.
, vol.12
, pp. 357-358
-
-
Page, R.D.1
-
28
-
-
0032540979
-
Control of peptide deformylase activity by metal cations
-
Ragusa, S., S. Blanquet, and T. Meinnel. 1998. Control of peptide deformylase activity by metal cations. J. Mol. Biol. 280:515-523.
-
(1998)
J. Mol. Biol.
, vol.280
, pp. 515-523
-
-
Ragusa, S.1
Blanquet, S.2
Meinnel, T.3
-
29
-
-
0032575507
-
Oxygen-mediated inactivation of peptide deformylase
-
Rajagopalan, P. T., and D. Pei. 1998. Oxygen-mediated inactivation of peptide deformylase. J. Biol. Chem. 273:22305-22310.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22305-22310
-
-
Rajagopalan, P.T.1
Pei, D.2
-
30
-
-
0000296163
-
Peptide deformylase: A new type of mononuclear iron protein
-
Rajagopalan, P. T., X. Yu, and D. Pei. 1997. Peptide deformylase: a new type of mononuclear iron protein. J. Am. Chem. Soc. 119:12418-12419.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 12418-12419
-
-
Rajagopalan, P.T.1
Yu, X.2
Pei, D.3
-
31
-
-
0004136246
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
-
Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning, a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
-
(1989)
Molecular Cloning, a Laboratory Manual, 2nd Ed.
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
32
-
-
0347993051
-
An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathway
-
Serero, A., C. Giglione, A. Sardini, J. Martinez-Sanz, and T. Meinnel. 2003. An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathway. J. Biol. Chem. 278:52953-52963.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 52953-52963
-
-
Serero, A.1
Giglione, C.2
Sardini, A.3
Martinez-Sanz, J.4
Meinnel, T.5
-
33
-
-
0037307109
-
Structural variation and inhibitor binding in polypeptide deformylase from four different bacterial species
-
Smith, K. J., C. M. Petit, K. Aubart, M. Smyth, E. McManus, J. Jones, A. Fosberry, C. Lewis, M. Lonetto, and S. B. Christensen. 2003. Structural variation and inhibitor binding in polypeptide deformylase from four different bacterial species. Protein Sci. 12:349-360.
-
(2003)
Protein Sci.
, vol.12
, pp. 349-360
-
-
Smith, K.J.1
Petit, C.M.2
Aubart, K.3
Smyth, M.4
McManus, E.5
Jones, J.6
Fosberry, A.7
Lewis, C.8
Lonetto, M.9
Christensen, S.B.10
-
34
-
-
0027968068
-
CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
-
Thompson, J. D., D. G. Higgins, and T. J. Gibson. 1994. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22:4673-4680.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 4673-4680
-
-
Thompson, J.D.1
Higgins, D.G.2
Gibson, T.J.3
-
35
-
-
19944427671
-
Mechanism of time-dependent inhibition of polypeptide deformylase by actinonin
-
Van Aller, G. S., R. Nandigama, C. M. Petit, W. E. DeWolf, Jr., C. J. Quinn, K. M. Aubart, M. Zalacain, S. B. Christensen, R. A. Copeland, and Z. Lai. 2005. Mechanism of time-dependent inhibition of polypeptide deformylase by actinonin. Biochemistry 44:253-260.
-
(2005)
Biochemistry
, vol.44
, pp. 253-260
-
-
Van Aller, G.S.1
Nandigama, R.2
Petit, C.M.3
DeWolf Jr., W.E.4
Quinn, C.J.5
Aubart, K.M.6
Zalacain, M.7
Christensen, S.B.8
Copeland, R.A.9
Lai, Z.10
-
36
-
-
0030683599
-
PAML: A program package for phylogenetic analysis by maximum likelihood
-
Yang, Z. 1997. PAML: a program package for phylogenetic analysis by maximum likelihood. Comput. Appl. Biosci. 13:555-556.
-
(1997)
Comput. Appl. Biosci.
, vol.13
, pp. 555-556
-
-
Yang, Z.1
-
37
-
-
0035885234
-
Deformylase as a novel antibacterial target
-
Yuan, Z., J. Trias, and R. J. White. 2001. Deformylase as a novel antibacterial target. Drug Discov. Today 6:954-961.
-
(2001)
Drug Discov. Today
, vol.6
, pp. 954-961
-
-
Yuan, Z.1
Trias, J.2
White, R.J.3
|