Interactions between impermeant blocking ions in the cystic fibrosis transmembrane conductance regulator chloride channel pore: Evidence for anion-induced conformational changes

Journal of Membrane Biology

Volumn 210, Issue 1, 2006, Pages 31-42

  Ge, Ning ^a   Linsdell, Paul ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Anion permeation; Blocker knock off; Ion channel; Ion ion interaction; Multi ion pore; Open channel block

Indexed keywords

5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; ANION; CHLORIDE CHANNEL; GLIBENCLAMIDE; IRON DERIVATIVE; PLATINUM DERIVATIVE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARTICLE; BINDING SITE; CHEMICAL INTERACTION; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION;

ANIMALS; ANIONS; CELL LINE; CHLORIDES; CRICETINAE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENZYME INHIBITORS; HUMANS; ION CHANNEL GATING; MEMBRANE POTENTIALS; MODELS, CHEMICAL; MOLECULAR CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33745894984     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-005-7028-2     Document Type: Article

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