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Volumn 21, Issue 8, 2006, Pages 1334-1339

Influence of methylated p15INK4b and p16INK4a genes on clinicopathological features in colorectal cancer

Author keywords

Colorectal cancer; Methylation; Prognosis

Indexed keywords

BISULFITE; CYCLIN DEPENDENT KINASE INHIBITOR 2B; PROTEIN P15; PROTEIN P16INK4A; UNCLASSIFIED DRUG;

EID: 33745824650     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2006.04137.x     Document Type: Article
Times cited : (40)

References (27)
  • 1
    • 0023748414 scopus 로고
    • Genetic alterations during colorectal-tumor development
    • Vogelstein B, Fearon ER, Hamilton SR et al. Genetic alterations during colorectal-tumor development. N. Engl. J. Med. 1988; 319: 525-32.
    • (1988) N. Engl. J. Med. , vol.319 , pp. 525-532
    • Vogelstein, B.1    Fearon, E.R.2    Hamilton, S.R.3
  • 3
    • 0028321632 scopus 로고
    • Infrequent K-ras activation in superficial-type (flat) colorectal adenomas and adenocarcinomas
    • Minamoto T, Sawaguchi K, Mai M, Yamashita N, Sugimura T, Esumi H. Infrequent K-ras activation in superficial-type (flat) colorectal adenomas and adenocarcinomas. Cancer Res. 1994; 54: 2841-4.
    • (1994) Cancer Res. , vol.54 , pp. 2841-2844
    • Minamoto, T.1    Sawaguchi, K.2    Mai, M.3    Yamashita, N.4    Sugimura, T.5    Esumi, H.6
  • 4
    • 0028921585 scopus 로고
    • Common occurrence of APC and K-ras gene mutations in the spectrum of colitis-associated neoplasias
    • Redston MS, Papadopoulos N, Caldas C, Kinzler KW, Kern SE. Common occurrence of APC and K-ras gene mutations in the spectrum of colitis-associated neoplasias. Gastroenterology 1995; 108: 383-92.
    • (1995) Gastroenterology , vol.108 , pp. 383-392
    • Redston, M.S.1    Papadopoulos, N.2    Caldas, C.3    Kinzler, K.W.4    Kern, S.E.5
  • 6
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N. Engl. J. Med. 2003; 349: 2042-54.
    • (2003) N. Engl. J. Med. , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 7
    • 0842278570 scopus 로고    scopus 로고
    • Epigenetic changes in colorectal cancer
    • Kondo Y, Issa JP. Epigenetic changes in colorectal cancer. Cancer Metastasis Rev. 2004; 23: 29-39.
    • (2004) Cancer Metastasis Rev. , vol.23 , pp. 29-39
    • Kondo, Y.1    Issa, J.P.2
  • 10
    • 0034671563 scopus 로고    scopus 로고
    • Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors
    • Jeffrey PD, Tong L, Pavletich NP. Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors. Genes Dev. 2000; 14: 3115-25.
    • (2000) Genes Dev. , vol.14 , pp. 3115-3125
    • Jeffrey, P.D.1    Tong, L.2    Pavletich, N.P.3
  • 11
    • 0036163745 scopus 로고    scopus 로고
    • Regulation of cyclin-Cdk activity in mammalian cells
    • Obaya AJ, Sedivy JM. Regulation of cyclin-Cdk activity in mammalian cells. Cell Mol. Life Sci. 2002; 59: 126-42.
    • (2002) Cell Mol. Life Sci. , vol.59 , pp. 126-142
    • Obaya, A.J.1    Sedivy, J.M.2
  • 12
    • 0033737604 scopus 로고    scopus 로고
    • ARF locus with reduced mRNA expression in colorectal cancer cell lines and clinicopathological features in primary tumors
    • ARF locus with reduced mRNA expression in colorectal cancer cell lines and clinicopathological features in primary tumors. Carcinogenesis 2000; 21: 2057-64.
    • (2000) Carcinogenesis , vol.21 , pp. 2057-2064
    • Zheng, S.1    Chen, P.2    McMillan, A.3
  • 13
    • 0028168242 scopus 로고
    • INK4B is apotential effector of TGF-β-induced cell cycle arrest
    • INK4B is apotential effector of TGF-β-induced cell cycle arrest. Nature 1994; 371: 257-61.
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 14
    • 0038189509 scopus 로고    scopus 로고
    • INK4b expression and correlates with poor prognosis
    • INK4b expression and correlates with poor prognosis. Leukemia 2003; 17: 919-24.
    • (2003) Leukemia , vol.17 , pp. 919-924
    • Teofili, L.1    Martini, M.2    Luongo, M.3
  • 15
    • 0035876192 scopus 로고    scopus 로고
    • Methylation of p15 and p16 genes in adult acute leukemia: Lack of prognostic significance
    • Chim CS, Tam CY, Liang R, Kwong YL. Methylation of p15 and p16 genes in adult acute leukemia: lack of prognostic significance. Cancer 2001; 91: 2222-9.
    • (2001) Cancer , vol.91 , pp. 2222-2229
    • Chim, C.S.1    Tam, C.Y.2    Liang, R.3    Kwong, Y.L.4
  • 16
    • 0033199104 scopus 로고    scopus 로고
    • Frequent methylation silencing of p15INK4b (MTS2) and p16INK4a (MTS1) in B-cell and T-cell lymphomas
    • Baur AS, Shaw P, Burri N, Delacrétaz F, Bosman FT, Chaubert P. Frequent methylation silencing of p15INK4b (MTS2) and p16INK4a (MTS1) in B-cell and T-cell lymphomas. Blood 1999; 94: 1773-81.
    • (1999) Blood , vol.94 , pp. 1773-1781
    • Baur, A.S.1    Shaw, P.2    Burri, N.3    Delacrétaz, F.4    Bosman, F.T.5    Chaubert, P.6
  • 17
    • 0036670250 scopus 로고    scopus 로고
    • Colorectal cancers with both p16 and p14 methylation show invasive characteristics
    • Hibi K, Nakayama H, Koike M et al. Colorectal cancers with both p16 and p14 methylation show invasive characteristics. Jpn. J. Cancer Res. 2002; 93: 883-7.
    • (2002) Jpn. J. Cancer Res. , vol.93 , pp. 883-887
    • Hibi, K.1    Nakayama, H.2    Koike, M.3
  • 20
    • 0035838125 scopus 로고    scopus 로고
    • Methylation of the hMLH1, 16, and Mdr1 genes in colorectal carcinoma: Associations with clinicopathological features
    • Shannon BA, Iacopetta BJ. Methylation of the hMLH1, 16, and Mdr1 genes in colorectal carcinoma: associations with clinicopathological features. Cancer Lett. 2001; 167: 91-7.
    • (2001) Cancer Lett. , vol.167 , pp. 91-97
    • Shannon, B.A.1    Iacopetta, B.J.2
  • 21
    • 0032589127 scopus 로고    scopus 로고
    • INK4a in anatomic and gender-specific subtypes of sporadic colorectal cancer
    • INK4a in anatomic and gender-specific subtypes of sporadic colorectal cancer. Cancer Epidem. Biomar. 1999; 8: 501-6.
    • (1999) Cancer Epidem. Biomar. , vol.8 , pp. 501-506
    • Wiencke, J.K.1    Zheng, S.2    Lafuente, A.3
  • 22
    • 0032401808 scopus 로고    scopus 로고
    • Aging and DNA methylation in colorectal mucosa and cancer
    • Ahuja N, Li Q, Mohan AL, Baylin SB, Issa JP. Aging and DNA methylation in colorectal mucosa and cancer. Cancer Res. 1998; 58: 5489-94.
    • (1998) Cancer Res. , vol.58 , pp. 5489-5494
    • Ahuja, N.1    Li, Q.2    Mohan, A.L.3    Baylin, S.B.4    Issa, J.P.5
  • 23
    • 0028875205 scopus 로고
    • Methylation of the 5′-CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • Gonzalez-Zulueta M, Bender CM, Yang AS et al. Methylation of the 5′-CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res. 1995; 55: 4531-5.
    • (1995) Cancer Res. , vol.55 , pp. 4531-4535
    • Gonzalez-Zulueta, M.1    Bender, C.M.2    Yang, A.S.3
  • 25
    • 0032820505 scopus 로고    scopus 로고
    • Hypermethylation of the p16 gene in sporadic T3N0M0 stage colorectal cancers: Association with DNA replication error and shorter survival
    • Liang JT, Chang KJ, Chen JC et al. Hypermethylation of the p16 gene in sporadic T3N0M0 stage colorectal cancers: association with DNA replication error and shorter survival. Oncology 1999; 57: 149-56.
    • (1999) Oncology , vol.57 , pp. 149-156
    • Liang, J.T.1    Chang, K.J.2    Chen, J.C.3
  • 26
    • 1542472892 scopus 로고    scopus 로고
    • Hypermethylation of the CDKN2A gene in colorectal cancer is associated with shorter survival
    • Maeda K, Kawakami K, Ishida Y, Ishiguro K, Omura K, Watanabe G. Hypermethylation of the CDKN2A gene in colorectal cancer is associated with shorter survival. Oncol. Rep. 2003; 10: 935-8.
    • (2003) Oncol. Rep. , vol.10 , pp. 935-938
    • Maeda, K.1    Kawakami, K.2    Ishida, Y.3    Ishiguro, K.4    Omura, K.5    Watanabe, G.6
  • 27
    • 0035863495 scopus 로고    scopus 로고
    • K-ras and p16 aberrations confer poor prognosis in human colorectal cancer
    • Esteller M, González S, Risques RA et al. K-ras and p16 aberrations confer poor prognosis in human colorectal cancer. J. Clin. Oncol. 2001; 19: 299-304.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 299-304
    • Esteller, M.1    González, S.2    Risques, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.