Mangifera indica L. extract protects T cells from activation-induced cell death

International Immunopharmacology

Volumn 6, Issue 9, 2006, Pages 1496-1505

  Hernández, Patricia ^a   Delgado, Rene ^a   Walczak, Henning ^b  

^a Center of Pharmaceutical Chemistry Cuba   (Cuba)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

AICD; Calcium; CD95L; JNK; Mangifera indica; MnSOD; ROS

Indexed keywords

ANTIOXIDANT; CALCIUM ION; CD3 ANTIGEN; DNA FRAGMENT; FAS LIGAND; MAGNIFERA INDICA EXTRACT; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MAGNIFERA INDICA; MEDICINAL PLANT; NORMAL HUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION;

APOPTOSIS; CELLS, CULTURED; HUMANS; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MANGIFERA; PLANT EXTRACTS; T-LYMPHOCYTES;

EID: 33745813567     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2006.03.014     Document Type: Article

References (41)

1. Green D.R., and Ware CF. Fas-ligand: privilege and peril. Proc Natl Acad Sci U S A 94 (1997) 5986-5990
2. Dhein J., Walczak H., Baumler C., Debatin K.M., and Krammer PH. Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature 373 (1995) 438-441
3. Bellgrau D., Gold D., Selawry H., Moore J., and Fronzusoff Duke R.C. A role for CD95 ligand in preventing graft rejection. Nature 377 (1995) 630-632
4. Drappa J., Vaishnaw A.K., Sullivan K.E., Chu J.L., and Elkon KB. Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity. N Engl J Med 335 (1996) 1643-1649
5. Rieux-Lancat F., Le Deist F., Hivroz C., Roberts I.A.G., Denatin K.M., Fischer A., et al. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 268 (1995) 1347-1349
6. Alimonti J.B., Ball T.B., and Fowke K.R. Mechanisms of CD4+T lymphocyte cell death in human immunodeficiency virus infection and AIDS. J Gen Virol 84 (2003) 1649-1661
7. Gulow K., Kaminski M., Darvas K., Suss D., Li-Weber M., and Krammer PH. HIV-1 trans-activator of transcription substitutes for oxidative signaling in activation-induced T cell death. J Immunol 174 (2005) 5249-5260
8. Eichhorst S.T., Muller M., Li-Weber M., Schulze-Bergkamen H., Angel P., and Krammer P.H. A novel AP-1 element in the CD95 ligand promoter is required for induction of apoptosis in hepatocellular carcinoma cells upon treatment with anticancer drugs. Mol Cell Biol 20 (2000) 7826-7837
9. Li-Weber M., Laur O., Dern K., and Krammer P.H. T cell activation-induced and HIV Tat-enhanced CD95 (APO-1/Fas) ligand transcription involves NF-κB. Eur J Immunol 30 (2000) 661-670
10. Li-Weber M., and Krammer P.H. The death of a T-cell: expression of the CD95 ligand. Cell Death Differ 9 (2002) 101-103
11. Rates S.M.K. Plants as source of drugs. Toxicon 39 (2001) 603-613
12. Nunez Selles A.J., Velez Castro H.T., Aguero-Aguero J., Gonzalez-Gonzalez J., Naddeo F., De Simone F., et al. Isolation and quantitative analysis of phenolic antioxidants, free sugars, and polyols from mango (Mangifera indica L.) stem bark aqueous decoction used in Cuba as a nutritional supplement. J Agric Food Chem 50 (2002) 762-766
13. Martinez G., Delgado R., Perez G., Garrido G., Nunez Selles A.J., and Leon O.S. Evaluation of the in vitro antioxidant activity of Mangifera indica L. extract (Vimang). Phytother Res 14 (2000) 424-427
14. Garrido G., González D., Delporte C., Backhouse N., Quintero G., Núñez A.J., et al. Analgesic and anti-inflammatory effects of Mangifera indica L. extract (VIMANG). Phytother Res 15 (2001) 18-21
15. García D., Delgado R., Ubeira F.M., and Leiro J. Modulator efects of rat macrophage function by Mangifera indica L. extract (Vimang) and mangiferin. Int Immunopharmacol 2 (2002) 797-806
16. Li-Weber M., Giaisi M., Baumann S., Treiber M.K., and Krammer P.H. The anti-inflammatory sesquiterpene lactone parthenolide suppresses CD95-mediated activation-induced-cell-death in T-cells. Cell Death Differ 9 (2002) 1256-1265
17. Suk K., Lee H., Kang S.S., Cho G.J., and Choi W.S. Flavonoid baicalein attenuates activation-induced cell death of brain microglia. J Pharmacol Exp Ther 305 (2003) 638-645
18. Li-Weber M., Weigand M.A., Giaisi M., Suss D., Treiber M.K., Baumann S., et al. Vitamin E inhibits CD95 ligand expression and protects T cells from activation-induced cell death. J Clin Invest 110 (2002) 681-690
19. Klas C., Debatin K.M., Jonker RR., and Krammer PH. Activation interferes with the APO-1 pathway in mature human T cells. Int Immunol 5 (1993) 625-630
20. Sprick M.R., Weigand M.A., Rieser E., Rauch C.T., Juo P., Blenis J., et al. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 12 (2000) 599-609
21. Nicoletti I., Migliorati G., Pagliacci M.C., Grignani F., and Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 139 (1991) 271-279
22. Rothe G., and Valet G. Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′, 7′-dichlorofluorescin. J Leukoc Biol 47 (1990) 440-448
23. DeGraffenried L.A., Friedrichs W.E., Fulcher L., Fernandes G., Silva J.M., Peralba J.M., et al. Eicosapentaenoic acid restores tamoxifen sensitivity in breast cancer cells with high Akt activity. Ann Oncol 14 (2003) 1051-1056
24. Devadas S., Zaritskaya L., Rhee S.G., Oberley L., and Williams M.S. Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and fas ligand expression. J Exp Med 195 (2002) 59-70
25. Aoshiba K., Yasui S., Hayashi M., Tamaoki J., and Nagai A. Role of p38-mitogen-activated protein kinase in spontaneous apoptosis of human neutrophils. J Biol Chem 162 (1999) 1692-1700
26. Shull S., Heintz N.H., Periasamy M., Manohar M., Janssen Y.M., Marsh J.P., et al. Differential regulation of antioxidant enzymes in response to oxidants. J Biol Chem 266 (1991) 24398-24403
27. Ho Y.S., Dey M.S., and Crapo J.D. Antioxidant enzyme expression in rat lungs during hyperoxia. Am J Physiol 270 (1996) L810-L818
28. Pardo Andreu G., Delgado R., Velho J., Inada N.M., Curti C., and Vercesi A.E. Mangifera indica L. extract (Vimang) inhibits Fe2+-citrate-induced lipoperoxidation in isolated rat liver mitochondria. Pharmacol Res 51 (2005) 427-435
29. Remirez D., Tafazoli S., Delgado R., Harandi A.A., and O'Brien PJ. Preventing hepatocyte oxidative stress cytotoxicity with Mangifera indica L. extract (Vimang). Drug Metabol Drug Interact 21 (2005) 19-29
30. Sanchez G.M., Re L., Giuliani A., Nunez-Selles A.J., Davison GP., and Leon-Fernandez O.S. Protective effects of Mangifera indica L. extract, mangiferin and selected antioxidants against TPA-induced biomolecules oxidation and peritoneal macrophage activation in mice. Pharmacol Res 42 (2000) 565-573
31. Pardo-Andreu G.L., Delgado R., Nunez-Selles A.J., and Vercesi AE. Dual mechanism of mangiferin protection against iron-induced damage to 2-deoxyribose and ascorbate oxidation. Pharmacol Res 53 (2006) 253-260
32. Catapano A.L. Antioxidant effect of flavonoids. Angiology 48 (1997) 39-44
33. Williamson J.R. Role of inositol lipid breakdown in the generation of intracellular signals: II. State of the art lecture. Hypertension 8 (1986) 140-156
34. Rengarajan J., Mittelstadt P.R., Mages H.W., Gerth A.J., Kroczek R.A., Ashwell J.D., et al. Sequential involvement of NFAT and Egr transcription factors in FasL regulation. Immunity 12 (2000) 293-300
35. Li-Weber M., Laur O., and Krammer PH. Novel Egr/NF-AT composite sites mediate activation of the CD95 (APO-1/Fas) ligand promoter in response to T cell stimulation. Eur J Immunol 29 (1999) 3017-3027
36. Leiro J., Arranza J.A., Yanez M., Ubeira F.M., Sanmarti{dotless}na M.L., and Orallo F. Expression profiles of genes involved in the mouse nuclear factor-kappa B signal transduction pathway are modulated by mangiferin. Int Immunopharmacol 4 (2004) 763-778
37. Diebolt M., and Andriantsitohaina R. Wine polyphenols modulate calcium handling in rat aorta: involvement of nitric oxide pathway. Fundam Clin Pharmacol 16 (2002) 289-296
38. Sabapathy K., Hu Y., Kallunki T., Schreiber M., David J.P., Jochum W., et al. JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development. Curr Biol 11 (1999) 116-125
39. Sabapathy K., Kallunki T., David J.P., Graef I., Karin M., and Wagner E.F. c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation. J Exp Med 193 (2001) 317-328
40. Gius D., Botero A., Shah S., and Curry HA. Intracellular oxidation/reduction status in the regulation of transcription factors NF-κB and AP-1. Toxicol Lett 106 (1999) 93-106
41. Beltran A.E., Alvarez Y., Xavier F.E., Hernanz R., Rodriguez J., Nunez A.J., et al. Vascular effects of the Mangifera indica L. extract (Vimang). Eur J Pharmacol 499 (2004) 297-305