Preventing hepatocyte oxidative stress cytotoxicity with Mangifera indica L. extract (Vimang)

Drug Metabolism and Drug Interactions

Volumn 21, Issue 1, 2005, Pages 19-29

  Remirez, Diadelis ^a   Tafazoli, Shahrzad ^b   Delgado, Rene ^c   Harandi, Asghar A ^d   O'Brien, Peter J ^b  

^a Centro para el Control Estatal de la Calidad de Los Medicamentos   (Cuba)

^b UNIVERSITY OF TORONTO   (Canada)

^c Centro de Quimica Farmaceutica   (Cuba)

^d TARBIAT MODARES UNIVERSITY   (Iran)

Author keywords

Hepatocytes; Lipid peroxidation; Mangifera indica L.; Rat; Reactive oxygen species; Vimang

Indexed keywords

CATECHIN; CUMENE HYDROPEROXIDE; GALLIC ACID; GALLIC ACID PROPYL ESTER; GLUCOSE OXIDASE; HYPOXANTHINE; MANGIFERA INDICA EXTRACT; MANGIFERIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG; VIMANG; XANTHINE OXIDASE;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG INHIBITION; LIPID PEROXIDATION; LIVER CELL; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; RAT;

EID: 23744494262     PISSN: 07925077     EISSN: None     Source Type: Journal    
DOI: 10.1515/DMDI.2005.21.1.19     Document Type: Article

References (25)

1. Zhu H, Bannenberg GL, Moldeus P, Shertzer HG. Oxidation pathways for the intracellular probe 2,7-dichlorofluorescein. Arch Toxicol 1994; 68: 582-587.
2. Gores GJ, Flarsheim CE, Dawson TL, Nieminen AL, Herman B, Lemasters JJ. Swelling, reductive stress and cell death during chemical hypoxia in hepatocytes. Am J Physiol 1989; 257: C347-C354.
3. 2+. Toxicology 2000; 143: 263-273.
4. 1. Free Radical Biol Med 1999; 27: 891-900.
5. Aruoma OI, Spencer JP, Rossi R, Aeschbach R, Khan A, Mahmood N, Munoz A, Murcia A, Butler J, Halliwell B. An evaluation of the antioxidant and antiviral action of extracts of rosemary and Provencal herbs. Food Chem Toxicol 1996; 34: 449-456.
6. Martinez G, Delgado R, Perez G, Garrido G, Nunez Selles AJ, Leon OS. Evaluation of the in vitro antioxidant activity of Mangifera indica L. extract (Vimang). Phytother Res 2000; 14: 424-427.
7. Sánchez GM, Re L, Guliani A, Nuñez Selles AJ, Davison GP, Leon-Fernandez OS. Protective effects of Mangifera indica L. extract, mangiferin and selected antioxidants against TPA-induced biomolecule oxidation and peritoneal macrophage activation. Pharmacol Res 2000; 42: 565-573.
8. Zheng MS, Lu ZY. Antiviral effect of mangiferin and isomangiferin on Herpes simplex virus. Chin Med J 1990; 103: 160-165.
9. Ichiki H, Miura T, Kubo M, Ishihara E, Komatsu Y, Tanigawa K, Okada M. New antidiabetic compounds, mangiferin and its glucoside. Biol Pharm Bull 1998; 21: 1389-1390.
10. Scartezzini P, Speroni E. Review on some plants of Indian traditional medicine with antioxidant activity. J Ethnopharmacol 2000; 71: 23-33.
11. Center of Pharmaceutical Chemistry. Pharmaceutical composition including a mixture of polyphenols, terpenoids, steroids, fatty acids and microelements with antioxidant, analgesic, anti-inflammatory and antispasmodic properties, Patent 203/98, OCPI, Havana, Cuba, 2002.
12. Das PC, Das A, Mandal S. Anti-inflammatory and antimicrobial activities of the seed kernel of Mangifera indica. Fitoterapia 1989; 60: 235-240.
13. Awe SO, Olajide OA, Oladiran OO, Makinde JM. Antiplasmodial and antipyretic screening of Mangifera indica extract. Phytother Res 1998; 12: 437-452.
14. Frame AD, Rios-Olivares De Jesus L, Ortiz D, Pagan J, Mendez S. Plants from Puerto Rico with anti-Mycobacterium tuberculosis properties. PR Health Sci J 1998; 17: 243-252.
15. Nuñez AJ, Velez Castro HT, Aguero JA, González GJ, Nadeo F, De Simone F, Rastrelli L. Isolation and quantitative analysis of phenolic antioxidants, free sugars and polyols from mango (Mangifera indica L) stem bark aqueous decocotion used in Cuba as a nutritional supplement. J Agric Food Chem 2003; 50: 762-766.
16. Moldeus P, Hogberg J, Orrenius S. Isolation and use of liver cells. Meth Enzymol 1978; 52: 60-71.
17. Smith MT, Thor H, Hartizell P, Orrenius S. The measurement of lipid peroxidation in isolated hepatocytes. Biochem Pharmacol 1982; 31: 19-26.
18. Zhao ZS, Khan S, O'Brien PJ. Catecholic iron complexes as cytoprotective superoxide scavengers against hypoxia:reoxygenation injury in isolated hepatocytes. Biochem Pharmacol 1998; 56: 825-830.
19. Siraki AG, Pourahmad J, Chan TS, Khan S, O'Brien PJ. Endogenous and endobiotic induced reactive oxygen species formation by isolated hepatocytes. Free Radical Biol Med 2002; 32: 2-10.
20. Martinez G, Delgado R, Leon OS, Perez G, Garrido G, Nunez AJ. Evaluation of the in vitro antioxidant activity of Mangifera indica L. extract (Vimang). Phytother Res 2000; 14: 424-427.
21. Galati G, O'Brien PJ. Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties. Free Radical Biol Med 2004; 37: 287-303.
22. Nakagawa Y, Moldeus P, Moore GA. Cytotoxicity of ortho-phenylphenol in isolated rat hepatocytes. Biochem Pharmacol 1992; 43: 159-165.
23. Rigobello MP, Stevanato R, Momo F, Fabris S, Scutari G, Boscolo R, Folda A, Bindoli A. Evaluation of the antioxidant properties of propofol and its nitrosoderivative. Comparison with homologue substituted phenols. Free Radical Res 2004; 38: 315-321.
24. Martinez G, Giuliani, Leon OS, Perez G and Nuñez AJ. Effect of Mangifera indica L. extract (QF808) on protein and hepatic microsome peroxidation. Phytother Res 2001; 15: 581-585.
25. Sato T, Kawamoto A, Tamura S, Tatsumi Y, Fujii T. Mechanism of antioxidant action of mangiferin. Chem Pharm Bull 1992; 40: 721-724.