Toll-like receptor priming sensitizes macrophages to proinflammatory cytokine gene induction by deoxynivalenol and other toxicants

Toxicological Sciences

Volumn 92, Issue 2, 2006, Pages 445-455

  Pestka, James ^a,b,c   Zhou, Hui Ren ^a,c  

^a Michigan State University   (United States)

^b NONE   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Deoxynivalenol; LPS; Macrophages; TLR; Xenobiotics

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYTOKINE; FLAGELLIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MYCOTOXIN; NICKEL CHLORIDE; POLYINOSINIC POLYCYTIDYLIC ACID; RESIQUIMOD; SHIGA TOXIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; TRICHOTHECENE; TRIPHENYLTIN; TUMOR NECROSIS FACTOR ALPHA; VOMITOXIN; XENOBIOTIC AGENT; ZEARALENONE; ZYMOSAN;

ANIMAL CELL; ARTICLE; BLOOD CULTURE; CELL TYPE; CONTROLLED STUDY; GENE EXPRESSION; GENE INDUCTION; HOST; IN VITRO STUDY; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE;

ANIMALS; CELL LINE; CYTOKINES; GENE EXPRESSION REGULATION; HUMANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, INBRED STRAINS; RNA, MESSENGER; SHIGA TOXIN; TOLL-LIKE RECEPTORS; TRICHOTHECENES; ZEARALENONE;

MURINAE;

EID: 33745796133     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfl012     Document Type: Article

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