ALS2CL, the novel protein highly homologous to the carboxy-terminal half of ALS2, binds to Rab5 and modulates endosome dynamics

FEBS Letters

Volumn 575, Issue 1-3, 2004, Pages 64-70

  Hadano, Shinji ^a,b   Otomo, Asako ^a   Suzuki Utsunomiya, Kyoko ^a   Kunita, Ryota ^b   Yanagisawa, Yoshiko ^b   Showguchi Miyata, Junko ^a   Mizumura, Hikaru ^b   Ikeda, Joh E ^a,b,c  

^a TOKAI UNIVERSITY   (Japan)

^b TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF OTTAWA   (Canada)

Author keywords

ALS, amyotrophic lateral sclerosis; ALS2CL, ALS2 carboxy terminal like; GEF, guanine nucleotide exchange factor; HSP, hereditary spastic paraplegia; MND, motor neuron disease; PLS, primary lateral sclerosis

Indexed keywords

ALS2 CARBOXY TERMINAL LIKE PROTEIN; ALSIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN DERIVATIVE; RAB PROTEIN; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CERCOPITHECIDAE; ENDOSOME; GENETIC CODE; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SEQUENCE HOMOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CARRIER PROTEINS; ENDOSOMES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HELA CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RAB5 GTP-BINDING PROTEINS; SEQUENCE ALIGNMENT; SUBCELLULAR FRACTIONS; TISSUE DISTRIBUTION;

EID: 4544335087     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2004.07.092     Document Type: Article

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