Protection from the toxicity of diisopropylfluorophosphate by adeno-associated virus expressing acetylcholinesterase

Toxicology and Applied Pharmacology

Volumn 214, Issue 2, 2006, Pages 152-165

  Li, Bin ^a   Duysen, Ellen G ^a   Poluektova, Larisa Y ^b   Murrin, L Charles ^b   Lockridge, Oksana ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

AAV 2; Acetylcholinesterase knockout mouse; DFP; Organophosphate

Indexed keywords

ACETYLCHOLINESTERASE; ANTIBODY; CHOLINESTERASE; COLLAGEN; DIMER; DYFLOS; PARVOVIRUS VECTOR; SODIUM CHLORIDE; TETRAMER;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BREATHING MUSCLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DIAPHRAGM; DRUG ADMINISTRATION ROUTE; DRUG BLOOD LEVEL; DRUG LIVER LEVEL; EMBRYO; ENZYME ACTIVITY; EXON; FEMALE; HEART; HUMAN; HUMAN CELL; IMMUNE SYSTEM; LUNG; MALE; MICROGLIA; MOTONEURON; MOUSE; NERVE CELL; NERVE ENDING; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RESPIRATORY FAILURE; SEROTYPE; VIRAL GENE THERAPY; WILD TYPE;

ACETYLCHOLINESTERASE; ADENOVIRIDAE; AMINO ACID SEQUENCE; ANIMALS; BRAIN; CHOLINESTERASE INHIBITORS; GENE THERAPY; GENETIC VECTORS; INJECTIONS, INTRA-ARTERIAL; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAVENOUS; INJECTIONS, SPINAL; ISOFLUROPHATE; MICE; MICE, KNOCKOUT; MOLECULAR WEIGHT; MUSCLE FIBERS; MUSCLE, SKELETAL; NEURONS; SURVIVAL ANALYSIS; TIME FACTORS;

ADENO-ASSOCIATED VIRUS; ADENO-ASSOCIATED VIRUS - 2; ANIMALIA; MURINAE;

EID: 33745698143     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2005.12.008     Document Type: Article

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