A novel method for purification of recombinant adeno-associated virus vectors on a large scale

Chinese Science Bulletin

Volumn 46, Issue 6, 2001, Pages 485-489

  Xiaobing, W ^a   Xiaoyan, D ^a   Zhijian, W ^a   Hui, C ^a   Dongbin, N ^a   Jianguo, Q ^a   Hong, W ^a   Yunde, H ^a  

^a State Key Laboratory for Molecular Virology and Genetic Engineering   (China)

Author keywords

Chloroform; Purification; Recombinant adeno associated virus

Indexed keywords

CHLOROFORM; MACROGOL; SODIUM CHLORIDE;

ADENO ASSOCIATED VIRUS; ARTICLE; NONHUMAN; PROVIRUS; REPRODUCIBILITY; VIRUS PURIFICATION; VIRUS RECOMBINANT;

ADENO-ASSOCIATED VIRUS;

EID: 0035003230     PISSN: 10016538     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03187263     Document Type: Article

References (10)

1. Generation of a recombinant herpes simplex virus which can provide packaging function for recombinant adeno-associated virus
2. High-titer recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 Rep and Cap
3. Production of recombinant adeno-associated viral vectors
4. Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses
5. Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield
6. Novel tools for production and purification of recombinant adeno-associated virus vectors
7. Membrane-associated heparin sulfate proteoglycan is a receptor for high-titer recombinant adeno-associated virus type 2 virions
8. Subcellular compartmentalization of adeno-associated virus type 2 virions
9. Construction of a series of adeno-associated virus vectors and their expression of β-galactosidase gene