Interaction Kinetics of Reversible Inhibitors and Substrates with Acetylcholinesterase and Its Fasciculin 2 Complex

Journal of Biological Chemistry

Volumn 276, Issue 7, 2001, Pages 4622-4633

  Radić, Zoran ^a   Taylor, Palmer ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYSIS; DIFFUSION; ENZYMES; HYDROLYSIS; REACTION KINETICS; SUBSTRATES;

DISSOCIATION RATE CONSTANTS; REVERSIBLE INHIBITORS;

BIOCHEMISTRY;

ACETYLCHOLINESTERASE; ENZYME INHIBITOR; FASCICULIN; FASCICULIN 2; UNCLASSIFIED DRUG; 7 (DIMETHYLCARBAMOYLOXY) N METHYLQUINOLINIUM; 7-(DIMETHYLCARBAMOYLOXY)-N-METHYLQUINOLINIUM; ACETYLCHOLINE; CARBAMIC ACID DERIVATIVE; CHOLINESTERASE INHIBITOR; DRUG DERIVATIVE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; QUINOLINE DERIVATIVE; SNAKE VENOM;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONFORMATION; DIFFUSION; DISSOCIATION CONSTANT; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; EQUILIBRIUM CONSTANT; HYDROLYSIS; LIGAND BINDING; LINEAR ENERGY TRANSFER; PKA; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTON TRANSPORT; ANIMAL; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; HUMAN; KINETICS; MACROMOLECULE; METABOLISM; MOUSE; PH;

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ANIMALS; CARBAMATES; CELL LINE; CHOLINESTERASE INHIBITORS; ELAPID VENOMS; HUMANS; HYDROGEN-ION CONCENTRATION; INDICATORS AND REAGENTS; KINETICS; MACROMOLECULAR SUBSTANCES; MICE; MODELS, MOLECULAR; QUINOLINIUM COMPOUNDS; SUBSTRATE SPECIFICITY;

EID: 0035895884     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M006855200     Document Type: Article

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