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Volumn 21, Issue 8, 2006, Pages 1257-1265

Inhibitory effects of Ligusticum chuanxiong on the proliferation of rat hepatic stellate cells

Author keywords

Apoptosis; Caspase 3; Cell cycle protein; Hepatic fibrosis; Ligusticum chuanxiong; smooth muscle actin

Indexed keywords

BROXURIDINE; CYCLIN D1; CYCLIN D2; LIGUSTICUM CHUANXIONG EXTRACT; MITOGEN ACTIVATED PROTEIN KINASE; PLANT EXTRACT; PLATELET DERIVED GROWTH FACTOR; PROTEIN P21; PROTEIN P27; UNCLASSIFIED DRUG;

EID: 33745675588     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2006.04326.x     Document Type: Article
Times cited : (19)

References (42)
  • 1
    • 0037220482 scopus 로고    scopus 로고
    • Liver fibrosis: From bench to bedside
    • Friedman SL. Liver fibrosis: from bench to bedside. J. Hepatol. 2003; 38: S38-53.
    • (2003) J. Hepatol. , vol.38
    • Friedman, S.L.1
  • 3
    • 0034810089 scopus 로고    scopus 로고
    • Cytokine receptors and signaling in hepatic stellate cells
    • Pinzani M, Marra F. Cytokine receptors and signaling in hepatic stellate cells. Semin. Liver Dis. 2001; 21: 397-416.
    • (2001) Semin. Liver Dis. , vol.21 , pp. 397-416
    • Pinzani, M.1    Marra, F.2
  • 5
    • 0036257518 scopus 로고    scopus 로고
    • Oxidative stress, plant-derived antioxidants and liver fibrosis
    • Gebhardt R. Oxidative stress, plant-derived antioxidants and liver fibrosis. Planta Med. 2002; 68: 289-96.
    • (2002) Planta Med. , vol.68 , pp. 289-296
    • Gebhardt, R.1
  • 6
    • 0032875149 scopus 로고    scopus 로고
    • Herbal products for liver diseases: A therapeutic challenge for the new millennium
    • Schuppan D, Jia JD, Brinkhaus B, Hahn EG. Herbal products for liver diseases: a therapeutic challenge for the new millennium. Hepatology 1999; 30: 1099-104.
    • (1999) Hepatology , vol.30 , pp. 1099-1104
    • Schuppan, D.1    Jia, J.D.2    Brinkhaus, B.3    Hahn, E.G.4
  • 7
    • 0032923588 scopus 로고    scopus 로고
    • Effects of Sho-saiko-to, a Japanese herbal medicine, on hepatic fibrosis in rats
    • Shimizu I, Ma Y-R, Mizobuchi Y et al. Effects of Sho-saiko-to, a Japanese herbal medicine, on hepatic fibrosis in rats. Hepatology 1999; 29: 149-60.
    • (1999) Hepatology , vol.29 , pp. 149-160
    • Shimizu, I.1    Ma, Y.-R.2    Mizobuchi, Y.3
  • 8
    • 0030796417 scopus 로고    scopus 로고
    • Silymarin retards collagen accumulation in early and advanced biliary fibrosis secondary to complete bile duct obliteration in rats
    • Boigk G, Stroedter L, Herbst H, Waldschmidt J, Riecken EO, Schuppan D. Silymarin retards collagen accumulation in early and advanced biliary fibrosis secondary to complete bile duct obliteration in rats. Hepatology 1997; 26: 643-9.
    • (1997) Hepatology , vol.26 , pp. 643-649
    • Boigk, G.1    Stroedter, L.2    Herbst, H.3    Waldschmidt, J.4    Riecken, E.O.5    Schuppan, D.6
  • 10
    • 0032212753 scopus 로고    scopus 로고
    • Salvia miltiorrhiza reduced experimentally induced hepatic fibrosis in rats
    • Wasser S, Ho JMS, Ang HK, Tan CEL. Salvia miltiorrhiza reduced experimentally induced hepatic fibrosis in rats. J. Hepatol. 1998; 29: 760-71.
    • (1998) J. Hepatol. , vol.29 , pp. 760-771
    • Wasser, S.1    Ho, J.M.S.2    Ang, H.K.3    Tan, C.E.L.4
  • 11
    • 0038578508 scopus 로고    scopus 로고
    • Herbal medicine Inchin-ko-to (TJ-135) prevents liver fibrosis and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient 1-amino acid-deficient diet
    • Sakaida I, Tsuchiya M, Kawaguchi K, Kimura T, Terai S, Okita K. Herbal medicine Inchin-ko-to (TJ-135) prevents liver fibrosis and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient 1-amino acid-deficient diet. J. Hepatol. 2003; 38: 762-9.
    • (2003) J. Hepatol. , vol.38 , pp. 762-769
    • Sakaida, I.1    Tsuchiya, M.2    Kawaguchi, K.3    Kimura, T.4    Terai, S.5    Okita, K.6
  • 12
    • 0002797851 scopus 로고
    • Ligusticum chuanxiong Hort
    • Tang W, Eisenbrand G, eds. Berlin: Springer-Verlag
    • Tang W, Eisenbrand G. Ligusticum chuanxiong Hort. In: Tang W, Eisenbrand G, eds. Chinese Drugs of Plant Origin. Berlin: Springer-Verlag, 1992; 609-12.
    • (1992) Chinese Drugs of Plant Origin , pp. 609-612
    • Tang, W.1    Eisenbrand, G.2
  • 14
    • 0034647592 scopus 로고    scopus 로고
    • The antiplatelet activity of tetramethylpyrazine is mediated through activation of NO synthase
    • Sheu JR, Kan YC, Hung WC, Lin CH, Yen MH. The antiplatelet activity of tetramethylpyrazine is mediated through activation of NO synthase. Life Sci. 2000; 67: 937-47.
    • (2000) Life Sci. , vol.67 , pp. 937-947
    • Sheu, J.R.1    Kan, Y.C.2    Hung, W.C.3    Lin, C.H.4    Yen, M.H.5
  • 15
    • 0029827998 scopus 로고    scopus 로고
    • Tetramethylpyrazine, a calcium antagonist
    • Pang PK, Shan JJ, Chiu KW. Tetramethylpyrazine, a calcium antagonist. Planta Med. 1996; 62: 431-5.
    • (1996) Planta Med. , vol.62 , pp. 431-435
    • Pang, P.K.1    Shan, J.J.2    Chiu, K.W.3
  • 16
    • 0345316690 scopus 로고    scopus 로고
    • Tetramethylpyrazine scavenges superoxide anion and decreases nitric oxide production in human polymorphonuclear leukocytes
    • Zhang Z, Wei T, Hou J, Li GYuS, Xin W. Tetramethylpyrazine scavenges superoxide anion and decreases nitric oxide production in human polymorphonuclear leukocytes. Life Sci. 2003; 72: 2465-72.
    • (2003) Life Sci. , vol.72 , pp. 2465-2472
    • Zhang, Z.1    Wei, T.2    Hou, J.3    Li, G.Yu.S.4    Xin, W.5
  • 17
    • 0032989514 scopus 로고    scopus 로고
    • Acute hemodynamic effects of tetramethylpyrazine and tetrandrine on cirrhotic rats
    • Huang Y-T, Chang F-C, Chen K-J, Hong C-Y. Acute hemodynamic effects of tetramethylpyrazine and tetrandrine on cirrhotic rats. Planta Med. 1999; 65: 130-4.
    • (1999) Planta Med. , vol.65 , pp. 130-134
    • Huang, Y.-T.1    Chang, F.-C.2    Chen, K.-J.3    Hong, C.-Y.4
  • 18
    • 0036069656 scopus 로고    scopus 로고
    • Hepatoprotective and therapeutic effects of tetramethylpyrazine on acute econazole-induced liver injury
    • Liu CF, Lin CC, Ng LT, Lin SC. Hepatoprotective and therapeutic effects of tetramethylpyrazine on acute econazole-induced liver injury. Planta Med. 2002; 68: 510-14.
    • (2002) Planta Med. , vol.68 , pp. 510-514
    • Liu, C.F.1    Lin, C.C.2    Ng, L.T.3    Lin, S.C.4
  • 19
    • 0033921113 scopus 로고    scopus 로고
    • An immortalized rat liver stellate cell (HSC-T6): A new cell model for the study of retinoid metabolism in vitro
    • Vogel S, Piantedosi R, Frnak J et al. An immortalized rat liver stellate cell (HSC-T6): a new cell model for the study of retinoid metabolism in vitro. J. Lipid Res. 2000; 41: 882-93.
    • (2000) J. Lipid Res. , vol.41 , pp. 882-893
    • Vogel, S.1    Piantedosi, R.2    Frnak, J.3
  • 20
    • 0037144235 scopus 로고    scopus 로고
    • Pepstatin a attenuates the inhibitory effect of N-acetyl-L-cysteine on proliferation of hepatic myofibroblasts (stellate cells)
    • Takashima T, Kawada N, Maeda N et al. Pepstatin A attenuates the inhibitory effect of N-acetyl-L-cysteine on proliferation of hepatic myofibroblasts (stellate cells). Eur. J. Pharmacol. 2002; 451: 265-70.
    • (2002) Eur. J. Pharmacol. , vol.451 , pp. 265-270
    • Takashima, T.1    Kawada, N.2    Maeda, N.3
  • 21
    • 0347297564 scopus 로고    scopus 로고
    • The antioxidant (-)-epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression
    • Chen A, Zhang L, Xu J, Tang J. The antioxidant (-)-epigallocatechin-3- gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression. Biochem. J. 2002; 368: 695-704.
    • (2002) Biochem. J. , vol.368 , pp. 695-704
    • Chen, A.1    Zhang, L.2    Xu, J.3    Tang, J.4
  • 22
    • 0346422479 scopus 로고    scopus 로고
    • Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1
    • Higuchi H, Grambihler A, Canbay A, Bronk SF, Gregory J, Gores GJ. Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1. J. Biol. Chem. 2004; 279: 51-60.
    • (2004) J. Biol. Chem. , vol.279 , pp. 51-60
    • Higuchi, H.1    Grambihler, A.2    Canbay, A.3    Bronk, S.F.4    Gregory, J.5    Gores, G.J.6
  • 23
    • 4444303261 scopus 로고    scopus 로고
    • Herb medicine Inchin-ko-to (TJ-135) regulates PDGF-BB-dependent signaling pathways of hepatic stellate cells in primary culture and attenuates development of liver fibrosis induced by thioacetamide administration in rats
    • Imanishi Y, Maeda N, Otogawa K, Seki S, Matsui H, Kawada N. Herb medicine Inchin-ko-to (TJ-135) regulates PDGF-BB-dependent signaling pathways of hepatic stellate cells in primary culture and attenuates development of liver fibrosis induced by thioacetamide administration in rats. J. Hepatol. 2004; 41: 242-50.
    • (2004) J. Hepatol. , vol.41 , pp. 242-250
    • Imanishi, Y.1    Maeda, N.2    Otogawa, K.3    Seki, S.4    Matsui, H.5    Kawada, N.6
  • 24
    • 0035798603 scopus 로고    scopus 로고
    • N-Acetylcysteine induces cell cycle arrest in hepatic stellate cells through its reducing activity
    • Kim K-Y, Rhim TY, Choi I, Soung-Soo Kim S-S. N-Acetylcysteine induces cell cycle arrest in hepatic stellate cells through its reducing activity. J. Biol. Chem. 2001; 276: 40591-8.
    • (2001) J. Biol. Chem. , vol.276 , pp. 40591-40598
    • Kim, K.-Y.1    Rhim, T.Y.2    Choi, I.3    Soung-Soo Kim, S.-S.4
  • 25
    • 0035895957 scopus 로고    scopus 로고
    • The neuroprotective effects of phytoestrogens on amyloid β protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons
    • Wang CN, Chi CW, Lin YL, Chen CF, Shiao YJ. The neuroprotective effects of phytoestrogens on amyloid β protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons. J. Biol. Chem. 2001; 276: 5287-95.
    • (2001) J. Biol. Chem. , vol.276 , pp. 5287-5295
    • Wang, C.N.1    Chi, C.W.2    Lin, Y.L.3    Chen, C.F.4    Shiao, Y.J.5
  • 26
    • 0024595042 scopus 로고
    • Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill
    • Hansen MB, Nielsen SL, Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J. Immunol. Methods 1989; 119: 203-10.
    • (1989) J. Immunol. Methods , vol.119 , pp. 203-210
    • Hansen, M.B.1    Nielsen, S.L.2    Berg, K.3
  • 27
    • 0021354540 scopus 로고
    • Oleic acid promotes the activation and translocation of phosphatidate phosphydrolase from the cytosol to particulate fractions of isolated rat hepatocytes
    • Cascales C, Mangiapane LH, Brindley DN. Oleic acid promotes the activation and translocation of phosphatidate phosphydrolase from the cytosol to particulate fractions of isolated rat hepatocytes. Biochem. J. 1984; 219: 911-16.
    • (1984) Biochem. J. , vol.219 , pp. 911-916
    • Cascales, C.1    Mangiapane, L.H.2    Brindley, D.N.3
  • 28
    • 0347950970 scopus 로고    scopus 로고
    • Green tea polyphenol epigallocatechin-3-gallate inhibits platelet-derived growth factor-induced proliferation of human hepatic stellate cell line LI90
    • Sakata R, Ueno T, Nakamura T, Sakamoto M, Torimura T, Sata M. Green tea polyphenol epigallocatechin-3-gallate inhibits platelet-derived growth factor-induced proliferation of human hepatic stellate cell line LI90. J. Hepatol. 2004; 40: 52-9.
    • (2004) J. Hepatol. , vol.40 , pp. 52-59
    • Sakata, R.1    Ueno, T.2    Nakamura, T.3    Sakamoto, M.4    Torimura, T.5    Sata, M.6
  • 29
    • 0035083958 scopus 로고    scopus 로고
    • Apoptosis of hepatic stellate cells: Involvement in resolution of biliary fibrosis and regulation by soluble growth factors
    • Issa R, Williams L, Trim N et al. Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors. Gut 2001; 48: 548-57.
    • (2001) Gut , vol.48 , pp. 548-557
    • Issa, R.1    Williams, L.2    Trim, N.3
  • 31
    • 0034830886 scopus 로고    scopus 로고
    • Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats
    • Wright MC, Issa R, Smart DE et al. Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats. Gastroenterology 2001; 121: 685-98.
    • (2001) Gastroenterology , vol.121 , pp. 685-698
    • Wright, M.C.1    Issa, R.2    Smart, D.E.3
  • 32
    • 0037663778 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of curcumin on rat hepatic stellate cell growth
    • Xu J, Lu Y, Chen A. Activation of peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of curcumin on rat hepatic stellate cell growth. Am. J. Physiol. Gastrointest. Liver Physiol. 2003; 285: G20-30.
    • (2003) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.285
    • Xu, J.1    Lu, Y.2    Chen, A.3
  • 33
    • 0032875460 scopus 로고    scopus 로고
    • Mechanism of action and in vivo role of platelet-derived growth factor
    • Heldin C-H, Westermark B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol. Rev. 1999; 79: 1283-316.
    • (1999) Physiol. Rev. , vol.79 , pp. 1283-1316
    • Heldin, C.-H.1    Westermark, B.2
  • 34
    • 0142026209 scopus 로고    scopus 로고
    • p38 MAP kinases: Key signalling molecules as therapeutic targets for inflammatory diseases
    • Kumar S, Boehm J, Lee JC. p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases. Nat. Rev. Drug Discov. 2003; 2: 717-26.
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 717-726
    • Kumar, S.1    Boehm, J.2    Lee, J.C.3
  • 35
    • 3342918498 scopus 로고    scopus 로고
    • The p38 MAP kinase pathway as a therapeutic target in inflammatory disease
    • Saklatvala J. The p38 MAP kinase pathway as a therapeutic target in inflammatory disease. Curr. Opin. Pharmacol. 2004; 4: 372-7.
    • (2004) Curr. Opin. Pharmacol. , vol.4 , pp. 372-377
    • Saklatvala, J.1
  • 36
    • 0032862560 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase activation differentially regulates platelet-derived growth factor's actions in hepatic stellate cells, and is induced by in vivo liver injury in the rat
    • Marra L, Arrighi MC, Lazi M et al. Extracellular signal-regulated kinase activation differentially regulates platelet-derived growth factor's actions in hepatic stellate cells, and is induced by in vivo liver injury in the rat. Hepatology 1999; 30: 951-8.
    • (1999) Hepatology , vol.30 , pp. 951-958
    • Marra, L.1    Arrighi, M.C.2    Lazi, M.3
  • 37
    • 0037174159 scopus 로고    scopus 로고
    • p38 MAPK mediates the regulation of alpha 1 (I) procollagen mRNA levels by TNF-alpha and TGF-beta in a cell line of rat hepatic stellate cells
    • Varela-Rey M, Montiel-Duarte C, Oses-Prieto JA et al. p38 MAPK mediates the regulation of alpha 1 (I) procollagen mRNA levels by TNF-alpha and TGF-beta in a cell line of rat hepatic stellate cells. FEBS Lett. 2002; 528: 133-8.
    • (2002) FEBS Lett. , vol.528 , pp. 133-138
    • Varela-Rey, M.1    Montiel-Duarte, C.2    Oses-Prieto, J.A.3
  • 38
    • 0030786204 scopus 로고    scopus 로고
    • Libronectin and cytokines increase JNK, ERK, AP-1 activity, and transin gene expression in rat hepatic stellate cells
    • Poulos JE, Weber JD, Bellezzo JM et al. Libronectin and cytokines increase JNK, ERK, AP-1 activity, and transin gene expression in rat hepatic stellate cells. Am. J. Physiol. 1997; 273: G804-11.
    • (1997) Am. J. Physiol. , vol.273
    • Poulos, J.E.1    Weber, J.D.2    Bellezzo, J.M.3
  • 39
    • 1442299357 scopus 로고    scopus 로고
    • MAP kinase signaling in diverse effects of ethanol
    • Aroor AR, Shukla SD. MAP kinase signaling in diverse effects of ethanol. Life Sci. 2004; 74: 2339-64.
    • (2004) Life Sci. , vol.74 , pp. 2339-2364
    • Aroor, A.R.1    Shukla, S.D.2
  • 40
    • 0037910211 scopus 로고    scopus 로고
    • The future of GI and liver research: Editorial perspectives. III. JNK/AP-1 regulation of hepatocyte death
    • Czaja MJ. The future of GI and liver research: editorial perspectives. III. JNK/AP-1 regulation of hepatocyte death. Am. J. Physiol. Gastrointest. Liver Physiol. 2003; 284: G875-9.
    • (2003) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.284
    • Czaja, M.J.1
  • 41
    • 0842324788 scopus 로고    scopus 로고
    • Recycling the cell cycle: Cyclins revisited
    • Murray AW. Recycling the cell cycle: cyclins revisited. Cell 2004; 116: 221-34.
    • (2004) Cell , vol.116 , pp. 221-234
    • Murray, A.W.1
  • 42
    • 0034660892 scopus 로고    scopus 로고
    • The Pezcoller lecture: Cancer cell cycles revisited
    • Sherr CJ. The Pezcoller lecture: cancer cell cycles revisited. Cancer Res. 2000; 60: 3689-95.
    • (2000) Cancer Res. , vol.60 , pp. 3689-3695
    • Sherr, C.J.1


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