Evolution of the mechanisms that establish the embryonic axes

Current Opinion in Genetics and Development

Volumn 16, Issue 4, 2006, Pages 413-418

  Stern, Claudio D ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN;

CELL FATE; CELL INTERACTION; EGG SIZE; EMBRYO DEVELOPMENT; GASTRULATION; MOSAICISM; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; ZYGOTE;

ANIMALS; BONE MORPHOGENETIC PROTEINS; EMBRYO; EMBRYONIC DEVELOPMENT; EVOLUTION; FIBROBLAST GROWTH FACTORS; GLYCOPROTEINS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; VERTEBRATES; WNT PROTEINS;

AMNIOTA; AVES; CHORDATA; INVERTEBRATA; MAMMALIA; VERTEBRATA;

EID: 33745611529     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gde.2006.06.005     Document Type: Review

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44. •].
45. •] reveal that the main axis of the mouse embryo develops not along the most prominent edge of the embryonic cylinder - the shape of the embryo at this stage (E4.5-E5.5) is like a flattened cylinder - but rather at right angles to it. These findings should make it easier to identify earlier markers of polarity before the primitive streak appears, which has been almost impossible until now.
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