The first cleavage of the mouse zygote predicts the blastocyst axis

Nature

Volumn 434, Issue 7031, 2005, Pages 391-395

  Plusa, Berenika ^a   Hadjantonakis, Anna Katerina ^b,c   Gray, Dionne ^a   Piotrowska Nitsche, Karolina ^a   Jedrusik, Agnieszka ^a   Papaioannou, Virginia E ^b   Glover, David M ^a   Zernicka Goetz, Magdalena ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; BIOMEDICAL ENGINEERING; LIVING SYSTEMS STUDIES; POLARIZATION; RESEARCH;

BLASTOCYSTS; EMBRYONIC-ABEMBRYONIC AXIS; PROGENY; ZYGOTES;

CELLS;

DEVELOPMENTAL BIOLOGY;

ANIMAL MODEL; ARTICLE; BLASTOCYST; BLASTOMERE; CELL CYCLE; CELL POPULATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; MOUSE; NONHUMAN; OOCYTE CLEAVAGE; PRIORITY JOURNAL; PROGENY; ZYGOTE; ANIMAL; C57BL MOUSE; CBA MOUSE; CELL DIVISION; CELL NUCLEUS; CHROMATIN; CYTOLOGY; DRUG EFFECT; FERTILIZATION; GROWTH, DEVELOPMENT AND AGING; MALE; METABOLISM; MORPHOGENESIS;

ANIMALIA; MAMMALIA;

CYTOCHALASIN D;

ANIMALS; BLASTOCYST; BLASTOMERES; BODY PATTERNING; CELL DIVISION; CELL NUCLEUS; CHROMATIN; CYTOCHALASIN D; FEMALE; FERTILIZATION; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; ZYGOTE;

EID: 15244338991     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03388     Document Type: Article

References (14)

1. Piotrowska, K. & Zernicka-Goetz, M. Role for sperm in spatial patterning of early mouse embryos. Nature 409, 517-521 (2001).
2. Gardner, R. L. Specification of embryonic axes begins before cleavage in normal mouse development. Development 128, 839-847 (2001).
3. Piotrowska, K., Wianny, F., Pedersen, R. A. & Zernicka-Goetz, M. Blastomeres arising from the first cleavage division have distinguishable fates in normal mouse development. Development 128, 3739-3748 (2001).
4. Fujimori, T., Kurotaki, Y., Miyazaki, J. I. & Nabeshima, Y. I. Analysis of cell lineage in 2- and 4-cell mouse embryos. Development 21, 5113-5122 (2003).
5. Piotrowska-Nitsche, K. & Zernicka-Goetz, M. Spatial arrangement of individual 4-cell stage blastomeres and the order in which they are generated correlate with blastocyst pattern in the mouse embryo. Mech. Dev. advance online publication, 18 December 2004 (doi:10.1016/j.mod.2004.11.014).
6. Piotrowska-Nitsche, K., Perea-Gomez, A., Haraguchi, S. & Zernicka-Goetz, M. Four-cell stage mouse blastomeres have different developmental properties. Development 132, 479-490 (2005).
7. Gardner, R. L. The early blastocyst is bilaterally symmetrical and its axis of symmetry is aligned with the animal-vegetal axis of the zygote in the mouse. Development 124, 289-301 (1997).
8. Plusa, B., Grabarek, T. B., Piotrowska, K., Glover, D. M. & Zernicka-Goetz, M. Site of the previous meiotic division defines cleavage orientation in the mouse embryo. Nature Cell Biol. 4, 811-815 (2002).
9. Gray, D. et al. First cleavage of the mouse embryos responds to change in egg shape at fertilisation. Curr. Biol. 14, 397-405 (2004).
10. Hadjantonakis, A.-K. & Papaioannou, V. High resolution dynamic in vivo imaging and tracking in mice. BMC Biotechnol. 4, 33 (2004).
11. Mayer, W., Smith, A., Fundele, R. & Haaf, T. Spatial separation of parental genomes in preimplantation mouse embryos. J. Cell Biol. 148, 629-634 (2000).
12. Donahue, R. P. Fertilization of the mouse oocyte: sequence and timing of nuclear progression to the two-cell stage. J. Exp. Zool. 180, 305-318 (1972).
13. Hiiragi, T. & Solter, D. First cleavage plane of the mouse egg is not predetermined but defined by the topology of the two apposing pronuclei. Nature 430, 360-364 (2004).
14. Garner, W. & McLaren, A. Cell distribution in chimaeric mouse embryos before implantation. J. Embryol. Exp. Morphol. 32, 495-503 (1974).