Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression - Transcriptional induction of p21WAF1 and p27kip1 by inhibition of PI-3K/AKT pathway

Glycobiology

Volumn 16, Issue 7, 2006, Pages 573-583

  Choi, Hee Jung ^a   Chung, Tae Wook ^a,b   Kang, Sung Koo ^a   Lee, Young Choon ^c   Ko, Jeong Heon ^d   Kim, Jong Guk ^b   Kim, Cheorl Ho ^a  

^a Sungkyunkwan University   (South Korea)

^b Kyungpook National University   (South Korea)

^c Dong A University   (South Korea)

^d Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Ganglioside GM3 (Neu5Ac 2,3Gal 1,4Glc 1,1Cer); MDM2; p21WAF1; p27kip1; PTEN

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; GANGLIOSIDE GM3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN P53;

AMINO ACID SEQUENCE; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME INHIBITION; FLOW CYTOMETRY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MOLECULAR MECHANICS; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL LINE, TUMOR; CELL MEMBRANE; CELL PROLIFERATION; COLORECTAL NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOWN-REGULATION; G(M3) GANGLIOSIDE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33745587546     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwj105     Document Type: Article

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