Coenzyme Q-dependent functions of plasma membrane in the aging process

Age

Volumn 27, Issue 2, 2005, Pages 139-146

  Navas, Plácido ^a   Villalba, José Manuel ^b   Lenaz, Giorgio ^c  

^a UNIVERSIDAD PABLO DE OLAVIDE   (Spain)

^b UNIVERSITY OF CÓRDOBA   (Spain)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Aging; Coenzyme Q; Oxidative stress; Plasma membrane; Redox system

Indexed keywords

CERAMIDE; CYTOKINE; MITOCHONDRIAL DNA; OXIDOREDUCTASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR NECROSIS FACTOR ALPHA; UBIDECARENONE;

AGING; ANIMAL CELL; CALORIC RESTRICTION; CELL MEMBRANE; ELECTRON TRANSPORT; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIFESPAN; MITOCHONDRION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; REVIEW; SIGNAL TRANSDUCTION;

EID: 33745543736     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-005-1632-z     Document Type: Review

References (93)

1. Arnold RS, Shi J, Murad E, Whalen AM, Sun CQ and Polavarapu R et al. (2001) Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1. Proc Natl Acad Sci USA 98: 5550-5555
2. Arroyo A, Navarro F, Navas P and Villalba JM (1998) Ubiquinol regeneration by plasma membrane ubiquinone reductase. Protoplasma 205: 107-113
3. Baker MA, Ly JD and Lawen A (2004) Characterization of VDAC1 as a plasma membrane NADH-oxidoreductase. Biofactors 21: 215-221
4. Barja G (2004) Aging in vertebrates, and the effect of caloric restriction: a mitochondrial free radical production-DNA damage mechanism? Biol Rev 79: 235-251
5. Barroso MP, Gómez-Díaz C, Villalba JM, Burón MI, López-Lluch G and Navas P (1997) Plasma membrane ubiquinone controls ceramide production and prevents cell death induced by serum withdrawal. J Bioenerg Biomembranes 29: 259-267
6. Bassenge E, Sommer O, Schwemmer M and Bunger R (2000) Antioxidant pyruvate inhibits cardiac formation of reactive oxygen species through changes in redox state. Am J Physiol Heart Circ Physiol 279: H2431-H2438
7. Bentinger M, Turunen M, Zhang XX, Wan YJ and Dallner G (2003) Involvement of retinoid X receptor alpha in coenzyme Q metabolism. J Mol Biol 326: 795-803
8. Beyer RE, Segura-Aguilar J, Di Bernardo S, Cavazzoni M, Fato R and Fiorentini D et al. (1996) The role of DT-diaphorase in the maintenance of the reduced antioxidant form of coenzyme Q in membrane systems, Proc Natl Acad Sci USA 93: 2528-2532
9. Brar SS, Corbin Z, Kennedy TP, Hemendinger R, Thornton L and Bommarius B et al. (2003) NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells. Am J Physiol Cell Physiol 285: C353-C369
10. Bremer J and Davis EJ (1975) Studies on the active transfer of reducing equivalents into mitochondria via the malate-aspartate shuttle. Biochim Biophys Acta 376: 387-397
11. Calabrese V, Scapagnini G, Ravagna A, Colombrita C, Spadaro F and Butterfield DA et al. (2004) Increased expression of heat shock proteins in rat brain during aging: relationship with mitochondrial function and glutathione redox state. Mech Ageing Dev 125: 325-335
12. Chatterjee S, Han H, Rollins S and Cleveland T (1999) Molecular cloning, characterization, and expression of a novel human neutral sphingomyelinase. J Biol Chem 274: 37407-37412
13. Constantinescu A, Maguire JJ and Packer L (1994) Interactions between ubiquinones and vitamins in membranes and cells. Mol Aspects Med 15: S57-S65
14. Crane FL, Hatefi Y, Lester RL and Widmer C (1957) Isolation of a quinone from beef heart mitochondria. Biochim Biophys Acta 25: 220-221
15. Crane FL, Sun IL, Clark MG, Grebing C and Löw H (1985) Transplasma membrane redox systems in growth and development. Biochim Biophys Acta 811: 233-264
16. D'Aurelio M, Merlo Pich M, Catani L, Sgarbi G, Bovina C and Formiggini G et al. (2001) Decreased Pasteur effect in platelets of aged individuals. Mech Ageing Dev 122: 823-833
17. Dbaibo GS, El-Assaad W, Krikorian A, Liu B, Diab K and Idriss NZ et al. (2001) Ceramide generation by two distinct pathways in tumor necrosis factor alpha-induced cell death. FEBS Lett 503: 7-12
18. de Cabo R, Cabello R, Rios M, López-Lluch G, Ingram DK and Lane MA et al. (2004) The plasma membrane antioxidant system of liver is increased in aging rats by calorie restriction. Exp Gerontol 39: 297-304
19. De Grey AD (1998) A mechanism proposed to explain the rise of oxidative stress during aging. J Anti-Aging Med 1: 53-66
20. De Grey AD (2000) The reductive hotspot hypothesis: an update. Arch Biochem Biophys 373: 295-301
21. De Grey AD (2002) The reductive hotspot hypothesis of mammalian aging: membrane metabolism magnifies mutant mitochondrial mischief. Eur J Biochem 269: 2003-2009
22. del Castillo-Olivares A, Nunez de Castro I and Medina MA (2000) Dual role of plasma membrane electron transport systems in defense. Crit Rev Biochem Mol Biol 35:197-220
23. Deleonardi G, Biondi A, D'Aurelio M, Pich MM, Stankov K and Falasca A et al. (2004) Plasma membrane oxidoreductase activity in cultured cells in relation to mitochondrial function and oxidative stress. Biofactors 20: 251-258
24. Drahota Z, Chowdhury SK, Floryk D, Mracek T, Wilhelm J and Rauchova H, et al. (2002) Glycerophospate-dependent hydrogen peroxide production by brown adipose tissue mitochondria and its activation by ferricyanide. J Bioenerg Biomembr 34: 105-113
25. Droge W (2002) Free radicals in the physiological control of cell function. Physiol Rev 82: 47-95
26. Droge W (2003) Oxidative stress and aging. Adv Exp Med Biol. 543: 191-200
27. Echtay KS, Bienengraeber M and Klingenberg M (2001) Role of intrahelical arginine residues in functional properties of uncoupling protein (UCP1). Biochemistry 40: 5243-5248
28. Esposito LA, Kokoszka JE, Waymire KG, Cottrell B, MacGregor GR and Wallace DC (2000) Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene. Free Radic Biol Med 28: 754-766
29. Fontaine E, Ichas F and Bernardi P (1998) A ubiquinone-binding site regulates the mitochondrial permeability transition pore. J Biol Chem 273: 25734-25740
30. 10 increase at the plasma membrane. Biochem Biophys Res Commun 234: 79-81
31. Hannun YA (1996) Functions of ceramide in coordinating cellular responses to stress. Science 274: 1855-1859
32. Jayadev S, Liu B, Bielawska AE, Lee JY, Nazaire F and Pushkareva MY et al. (1995) Role for ceramide in cell cycle arrest. J Biol Chem 270: 2047-2052
33. Kagan VE and Tyurina YY (1998) Recycling and redox cycling of phenolic antioxidants. Ann NY Acad Sci 20: 425-434
34. Kagan VE, Serbinova EA and Packer L (1990) Antioxidant effects of ubiquinones in microsomes and mitochondria are mediated by tocopherol recycling. Biochem Biophys Res Commun 169: 851-857
35. Kagan VE, Arroyo A, Tyurin VA, Tyurina YY, Villalba JM and Navas P (1998) Plasma membrane NADH-coenzyme Qo reductase generates semiquinone radicals and recycles vitamin E homologue in a superoxide-dependent reaction. FEBS Lett 428: 43-46
36. Kawamukai M (1998) Recent advance of the biosynthesis and the function of ubiquinone. Seikagaku 70: 1344-1349. Japanese
37. King MP and Attardi G (1989) Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation. Science 246: 500-503
38. Kishi T, Morre DM and Morre DJ (1999) The plasma membrane NADH oxidase of HeLa cells has hydroquinone oxidase activity. Biochim Biophys Acta 1412: 66-77
39. Kudin AP, Bimpong-Buta NY-B, Vielhaber S, Elger CE and Kunz WS (2004) Characterization of superoxide-producing sites in isolated brain mitochondria. J Biol Chem 279: 4127-4135
40. Kushnareva Y, Murphy AN and Andreyev A (2002) Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state. Biochem J 368: 545-553
41. Larm JA, Vaillant F, Linnane AW and Lawen A (1994) Up-regulation of the plasma membrane oxidoreductase as a prerequisite for the viability of human Namalwa ρ° cells. J Biol Chem 269: 30097-30100
42. Lass A, Agarwal S and Sohal RS (1997) Mitochondrial ubiquinone homologues, superoxide radical generation, and longevity in different mammalian species. J Biol Chem 272: 19199-19204
43. Lenaz G (1998) Role of mitochondria in oxidative stress and ageing. Biochim Biophys Acta 1366: 53-67
44. Lenaz G (2001) The mitochondrial production of reactive oxygen species: mechanisms and implications in human pathology. IUBMB Life 52: 159-164
45. Lenaz G, Cavazzoni M, Genova ML, D'Aurelio M, Pich MM and Pallotti F et al. (1998) Oxidative stress, antioxidant defences and aging. Biofactors 8: 195-204
46. Lenaz G, Paolucci U, Fato R, D'Aurelio M, Parenti Castelli G and Sgarbi G et al. (2002) Enhanced activity of the plasma membrane oxidoreductase in circulating lymphocytes from insulin-dependent diabetes mellitus patients. Biochem Biophys Res Commun 290: 1589-1592
47. Liebler DC (1993) The role of metabolism in the antioxidant function of vitamin E. Crit Rev Toxicol 23: 147-169
48. Lightle SA, Oakley JI and Nikolova-Karakashian MN (2000) Activation of sphingolipid turnover and chronic generation of ceramide and sphingosine in liver during aging. Mech Ageing Dev 120: 111-125
49. Lind C, Cadenas E, Hochstein P and Ernster L (1990) DT-diaphorase: purification, properties, and function. Methods Enzymol 186: 287-301
50. Linnane AW, Marzuki S, Ozawa T and Tanaka M (1989) Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases. Lancet 7: 642-645
51. Liu B, Obeid LM and Hannun YA (1997) Sphingomyelinases in cell regulation. Semin Cell Dev Biol 8: 311-322
52. Lopez-Lluch G, Barroso MP, Martin SF, Fernandez-Ayala DJM, Gomez-Diaz C and Villalba JM et al. (1999) Role of plasma membrane coenzyme Q on the regulation of apoptosis. Biofactors 9: 171-177
53. Macho A, Blázquez MV, Navas P and Muñoz E (1998) Induction of apoptosis by vallinoid compounds is independent of Jun krnase and AP-1. Cell Growth Differ 9: 277-286
54. Macho A, Calzado MA, Muñoz-Blanco J, Gómez-Díaz C, Gajate C and Mollinedo F et al. (1999) Selective induction of apoptosis by capsaicin in transformed cells: the role of reactive oxygen species and calcium. Cell Death Differ 6: 155-165
55. 2 and plays an integral role in insulin signal transduction. Mol Cell Biol 24: 1844-1854
56. Malik SG, Vaillant F and Lawen A (2004) Plasma membrane NADH-oxidoreductase in cells carrying mitochondrial DNA G11778A mutation and in cells devoid of mitochondrial DNA (rho0). Biofactors 20: 189-198
57. Martín SF, Navarro F, Forthoffer N, Navas P and Villalba JM (2001) Neutral magnesium-dependent sphingomyelinase from liver plasma membrane: Purificacion and inhibition by ubiquinol. J Bioenerg Biomembranes 33: 143-153
58. Martin SF, Gomez-Diaz C, Navas P and Villalba JM (2002) Ubiquinol inhibition of neutral sphingomyelinase in liver plasma membrane: specific inhibition of the Mg(2+)-dependent enzyme and role of isoprenoid chain. Biochem Biophys Res Commun 297: 581-586
59. Martin-Romero FJ, Garcia-Martin E and Gutierrez-Merino C (2002) Inhibition of oxidative stress produced by plasma membrane NADH oxidase delays low-potassium-induced apoptosis of cerebellar granule cells. J Neurochem 82: 705-715
60. Masoro EJ (2001) Dietary restriction: current status. Aging (Milano). 13: 261-262
61. Melov S, Coskun P, Patel M, Tuinstra R, Cottrell B and Jun AS et al. (1999) Mitochondrial disease in superoxide dismutase 2 mutant mice. Proc Natl Acad Sci USA 96: 846-851
62. Miquel J, Economos AC, Fleming J and Johnson JE Jr (1980) Mitochondrial role in cell aging. Exp Gerontol 15: 575-591
63. Mizushima N, Koike R, Kohsaka H, Kushi Y, Handa S and Yagita H et al. (1996) Ceramide induces apoptosis via CPP32 activation. FEBS Lett 395: 267-271
64. Morré DJ and Morré DM (2004) Plasma membrane electron transport. A metabolic process deserving of renewed interest. Biofactors 20: 183-187
65. Morré DJ, Pogue R and Morré DM (1999) A multifunctional hydroquinone oxidase of the external cell surface and sera. Biofactors 9: 179-187
66. Morré DM, Lenaz G and Morré DJ (2000) Surface oxidase and oxidative stress propagation in aging. J Exp Biol 203: 1513-1521
67. Navarro F, Villalba JM, Crane FL, Mackellar WC and Navas P (1995) A phospholipid-dependent NADH-coenzyme Q reductase from liver plasma membrane. Biochem Biophys Res Commun 212: 138-143
68. Navarro F, Navas P, Burgess JR, Bello RI, De Cabo R and Arroyo A et al. (1998) Vitamin E and selenium deficiency induces expression of the ubiquinone-dependent antioxidant system at the plasma membrane. FASEB J 12: 1665-1673
69. Obeid LM, Linardic CM, Karolak LA and Hannun YA (1993) Programmed cell death induced by ceramide. Science 259: 1769-1771
70. Olsson U, Lundgren E, Segura-Aguilar J, Messing-Eriksson A, Andersson K and Becedas L et al. (1993) Effects of selenium deficiency on xenobiotic-metabolizing and other enzymes in rat liver. Int J Vitam Nutr Res 63: 31-37
71. Petkova DH, Momchilova-Pankova AB, Markovska TT and Koumanov KS (1988) Age-related changes in rat liver plasma membrane sphingomyelinase activity. Exp Gerontol 23: 19-24
72. Prata C, Maraldi T, Zambonin L, Fiorentini D, Hakim G and Landi L (2004) ROS production and Glutl activity in two human megakaryocytic cell lines. Biofactors 20: 223-233
73. Raff MC, Barres BA, Burne JF, Coles HS, Ishizaki Y and Jacobson MD (1993) Programmed cell death and the control of the survival: lessons from the nervous system. Science 262: 695-700
74. Rauchova H, Drahota Z and Lenaz G (1995) Function of coenzyme Q in the cell: some biochemical and physiological properties Physiol Res 44: 209-216
75. Rushmore TH, Morton MR and Pickett CB (1991) The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity. J Biol Chem 266: 11632-11639
76. Samhan-Arias AK, Martin-Romero FJ and Gutierrez-Merino C (2004) Kaempferol blocks oxidative stress in cerebellar granule cells and reveals a key role for reactive oxygen species production at the plasma membrane in the commitment to apoptosis. Free Radic Biol Med 37: 48-61
77. Santos-Ocaña C, Villalba JM, Córdoba F, Padilla S, Crane FL and Clarke CF et al. (1998) Genetic evidence for coenzyme Q requirement in plasma membrane electron transport. J Bioenerg Biomembranes 30: 465-475
78. Sauer H, Gunther J, Hescheler J and Wartenberg M (2000) Thalidomide inhibits angiogenesis in embryoid bodies by the generation of hydroxyl radicals. Am J Pathol 156: 151-158
79. Sauer H, Wartenberg M and Hescheler J (2001) Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol Biochem 11: 173-186
80. Sharma MK and Buettner GR (1993) Interaction of vitamin C and vitamin E during free radical stress in plasma: an ESR study. Free Radic Biol Med 14:649-653
81. Shiose A, Kuroda J, Tsuruya K, Hirai M, Hirakata H and Naito S et al. (2001) A novel superoxide-producing NAD(P)H oxidase in kidney. J Biol Chem 276: 1417-1423
82. Spence MW and Burgess JK (1978) Acid and neutral sphingomyelinases of rat brain. Activity in developing brain and regional distribution in adult brain. J Neurochem 30: 917-919
83. Stoyanovsky DA, Osipov AN, Quinn PJ and Kagan VE (1995) Ubiquinone-dependent recycling of vitamin E radicals by superoxide. Arch Biochem Biophys 323: 343-351
84. Sun IL, Sun EE, Crane FL, Morré DJ, Lindgren A and Löw H (1992) Requirement for coenzyme Q in plasma membrane electron transport. Proc Natl Acad Sci USA 89: 11126-11130
85. Takahashi T, Shitashige M, Okamoto T, Kishi T, and Goshima K (1992) A novel ubiquinone reductase activity in rat cytosol. FEBS Lett 314: 331-334
86. Takahashi T, Yamaguchi T, Shitashige M, Okamoto T and Kishi T (1995) Reduction of ubiquinone in membrane lipids by rat liver cytosol and its involvement in the cellular defence system against lipid peroxidation. Biochem J 309: 883-890
87. Thannickal VJ, Day RM, Klinz SG, Bastien MC, Larios JM and Fanburg BL (2000) Ras-dependent and -independent regulation of reactive oxygen species by mitogenic growth factors and TGF-beta1. FASEB J 14: 1741-1748
88. Turunen M, Olsson J and Dallner G (2004) Metabolism and function of coenzyme Q. Biochim Biophys Acta 1660: 171-199
89. Vaquero EC, Edderkaoui M, Pandol SJ, Gukovsky I and Gukovskaya AS (2004) Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells. J Biol Chem 279: 34643-34654
90. Villalba JM, Navarro F, Córdoba F, Serrano A, Arroyo A and Crane FL et al. (1995) Coenzyme Q reductase from liver plasma membrane: purification and role in trans-plasma-membrane electron transport. Proc Natl Acad Sci USA 92: 4887-4891
91. Villalba JM, Crane FL and Navas P (1998) In: Asard H, Bërczi A and Caubergs RJ (eds) Plasma Membrane Redox Systems and Their Role in Biological Stress and Disease, pp 247-265. Kluwer, Dordrecht
92. Wolvetang EJ, Larm JA, Moutsoulas P and Lawen A (1996) Apoptosis induced by inhibitors of the plasma membrane NADH-oxidase involves Bcl-2 and calcineurin. Cell Growth Differ 7: 1315-1325
93. Yang S, Madyastha P, Bingel S, Ries W and Key L (2001) A new superoxide-generating oxidase in murine osteoclasts. J Biol Chem 276: 5452-5458