TGF-β-1 up-regulates cyclin D1 expression in colo-357 cells, whereas suppression of cyclin D1 levels is associated with down-regulation of the type I TGF-β receptor

International Journal of Cancer

Volumn 83, Issue 2, 1999, Pages 247-254

  Kornmann, Marko ^a,b   Tangvoranuntakul, Pam ^a   Korc, Murray ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; GROWTH REGULATION; HUMAN; HUMAN CELL; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; RECEPTOR DOWN REGULATION; TRANSCRIPTION REGULATION;

ACTIVIN RECEPTORS, TYPE I; CELL DIVISION; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GROWTH INHIBITORS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; OLIGONUCLEOTIDES, ANTISENSE; PANCREATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0032885350     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19991008)83:2<247::AID-IJC17>3.0.CO;2-0     Document Type: Article

References (41)

1. ARBER, N., DOKI, Y., HAN E.K., SGABBATO, A., ZHOU, P., KIM, N.H., DELOHERY, T., KLEIN, M.G., HOLT, P.R. and WEINSTEIN, I.B., Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells. Cancer Res., 57, 1569-1574 (1997).
2. ARELLANO, M. and MORENO, S., Regulation of CDK/cyclin complexes during the cell cycle. Int. J. Biochem. Cell Biol., 29, 559-573 (1997).
3. BALDWIN, R.L. and KORC, M., Growth inhibition of human pancreatic carcinoma cells by transforming growth factor beta-1. Growth Factors, 8, 23-34 (1993).
4. BERGMANN, U., FUNATOMI, H., YOKOYAMA, M., BEGER, H.G. and KORC, M., Insulin-like growth factor I overexpression in human pancreatic cancer: evidence for autocrine and paracrine roles. Cancer Res., 55, 2007-2011 (1995).
5. BLOOM, B.B., HUMPHRIES, D.E., KUANG, P.-P., FINE, A. and GOLDSTEIN, R.H., Structure and expression of the promoter for the R4/ALK5 human type I transforming growth factor-β receptor: regulation by TGF-β. Biochim. biophys. Acta, 1312, 243-248 (1996).
6. BRANDES, M.E., WAKEFIELD, L.M. and WAHL, S.M., Modulation of monocyte type I transforming growth factor-β receptors by inflammatory stimuli. J. biol. Chem., 266, 19697-19703 (1991).
7. CARNEIRO, C., ALVAREZ, C.V., ZALVIDE, J., VIDAL, A. and DOMINGUEZ, F., TGF-β1 actions on FRTL-5 cells provide a model for the physiological regulation of thyroid growth. Oncogene, 16, 1455-1465 (1998).
8. CHANG, D.J., JI, C., KIM, K.K., CASINGHINO, S., MCCARTHY, T.L. and CENTRELLA, M., Reduction in transforming growth factor-β receptor I expression and transcription factor CBFa1 on bone cells by glucocorticoid. J. biol. Chem., 273, 4892-4896 (1998).
9. DUFOURNY, B., ALBLAS, J., VAN TEEFFELEN, H.A., VAN SCHAIK, F.M., VAN DER BURG, B., STEENBERGH, P.H. and SUSSENBACH, J.S., Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase. J. biol. Chem., 272, 31163-31171 (1997).
10. EWEN, M.E., SLUSS, H.K., WHITEHOUSE, L.L. and LIVINGSTON, D.M., TGF-β inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell, 74, 1009-1020 (1993).
11. Kip1. Oncogene, 13, 2447-2457 (1996).
12. FRIESS, H., YAMANAKA, Y., BÜCHLER, M., EBERT, M., BEGER, H.G., GOLD, L.I. and KORC, M., Enhanced expression of transforming growth factor-β isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology, 105, 1846-1856 (1993).
13. GANSAUGE, S., GANSAUGE, F., RAMADANI, M., STOBBE, H., RAU, B., HARADA, N. and BEGER, H.G., Overexpression of cyclin D1 in human pancreatic carcinoma is associated with poor prognosis. Cancer Res., 57, 1634-1637 (1997).
14. 1 cyclins and cyclin-dependent protein kinases. Proc. nat. Acad. Sci. (Wash.), 90, 10315-10319 (1993).
15. GRANA, X. and REDDY, E.P., Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). Oncogene, 11, 211-219 (1995).
16. waf1 expression and growth inhibition by transforming growth factor β involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells. Cancer Res., 57, 3929-3934 (1997).
17. HELDIN, C.-K., MIYAZONO, K. and DIJKE, P.T., TGF-β signaling from cell membrane to nucleus through SMAD proteins. Nature (Lond.), 390, 465-471 (1997).
18. JEOUNG, D.I., TANG, B. and SONENBERG, M., Mitogenic response to TGF-β in 3T3-F442A cells. Biochem. biophys. Res. Comm., 216, 964-969 (1995).
19. JI, C., CASINGHINO, S., MCCARTHY, T.L. and CENTRELLA, M., Multiple and essential Sp1 binding sites in the promoter for transforming growth factor-β type I receptor. J. biol. Chem., 272, 21260-21267 (1997).
20. KARLSEDER, J., ROTHENEDER, H. and WINTERSBERGER, E., Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2F. Mol. cell. Biol., 16, 1659-1667 (1996).
21. KLEEFF, J. and KORC, M., Up-regulation of transforming growth factor (TGF)-β receptors by TGF-β1 in COLO-357 cells. J. biol. Chem., 273, 7495-7500 (1998).
22. KLEEFF, J., WILDI, S., FRIESS, H. and KORC, M., Ligand induced upregulation of the type II transforming growth factor-β (TGF-β) receptor enhances TGF-β responsiveness in COLO-357 cells. Pancreas, 18, 364-370 (1999).
23. KO, T.C., SHENG, H.M., REISMAN, D., THOMPSON, E.A. and BEAUCHAMP, R.D., Transforming growth factor-β1 inhibits cyclin D1 expression in intestinal epithelial cells. Oncogene, 10, 177-184 (1995).
24. KORNMANN, M., ARBER, N. and KORC, M., Inhibition of basal and mitogen-stimulated pancreatic cancer cell growth by cyclin D1 antisense is associated with loss of tumorigenicity and potentiation of cytotoxicity to cisplatinum. J. clin. Invest., 101, 344-352 (1998a).
25. KORNMANN, M., ISHIWATA, T., ITAKURA, J., TANGVORANUNTAKUL, P., BEGER, H.G. and KORC, M., Increased cyclin D1 in human pancreatic cancer is associated with decreased postoperative survival. Oncology, 55, 363-369 (1998b).
26. LAIHO, M., DECAPRIO, J.A., LUDLOW, J.W., LIVINGSTON, D.M. and MASSAGUÉ, J., Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation. Cell, 62, 175-185 (1990).
27. INK4B through an Sp1 consensus site. J. biol. Chem., 270, 26750-26753 (1995).
28. LIN, S.Y., BLACK, A.R., KOSTIC, D., PAJOVIC, S., HOOVER, C.M. and AZIZKHAN, J.C., Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction. Mol. cell Biol., 16, 1668-1675 (1996).
29. 1 checkpoint. Mol. cell. Biol., 16, 6917-6925 (1996).
30. MASSAGUÉ, J., The transforming growth factor-β family. Ann. Rev. Cell Biol., 6, 597-641 (1990).
31. MASSAGUÉ, J., TGF-β signaling: receptors, transducers, and Mad proteins. Cell, 85, 947-950 (1996).
32. MORELAND, R.B., TRAISH, A., MCMILLAN, M.A., SMITH, B., GOLDSTEIN, I. and DE TEJADA, I.S., PGE1 suppresses the induction of collagen synthesis by transforming growth factor-β 1 in human corpus cavernosum smooth muscle. J. Urol., 153, 826-834 (1995).
33. OKAMOTO, A., JIANG, W., KIM, S.-J., SPILLARE, E.A., STONER, G.D., WEINSTEIN, I.B. and HARRIS, C.C., Overexpression of human cyclin D1 reduces the transforming growth factor-β (TGF-β) type II receptor and growth inhibition by TGF-β1 in an immortalized human esophageal epithelial cell line. Proc. nat. Acad. Sci. (Wash.), 91, 11576-11580 (1994).
34. 1 events and regulation of cell proliferation. Science, 246, 603-608 (1989).
35. RAO, S.S. and KOHTZ, D.S., Positive and negative regulation of D-type cyclin expression in skeletal myoblasts by basic fibroblast growth factor and transforming growth factor-β. A role for cyclin D1 in control of myoblast differentiation. J. biol. Chem., 270, 4093-4100 (1995).
36. 1 phase and cell cycle regulation by TGF-β. Adv. Cancer Res., 82, 165-218 (1997).
37. RAVITZ, M.J., YAN, S., DOLCE, C., KINNIBURGH, A.J. and WENNER, C.E., Differential regulation of p27 and cyclin D1 by TGF-β and EGF in C3H 10T1/2 mouse fibroblasts. J. Cell Physiol., 168, 510-520 (1996).
38. REYNISDOTTIR, I., POLYAK, K., IAVARONE, A. and MASSAGUÉ, J., Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Develop., 9, 1831-1845 (1995).
39. SATTERWHITE, D.J., AAKRE, M.E., GORSKA, A.E. and MOSES, H.L., Inhibition of cell growth by TGF-β1 is associated with inhibition of B-myb and cyclin A in both BALB/MK and Mv1Lu cells. Cell Growth Differentiation, 5, 789-799 (1994).
40. UDVADIA, A.J., TEMPLETON, D.J. and HOROWITZ, J.M., Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression. Proc. nat. Acad. Sci. (Wash.), 92, 3953-3957 (1995).
41. ZHOU, P., JIANG, W., ZHANG, Y.J., KAHN, S.M., SCHIEREN, I., SANTELLA, R.M. and WEINSTEIN, I.B., Antisense to cyclin D1 inhibits growth and reverses the transformed phenotype of human esophageal cancer cells. Oncogene, 11, 571-580 (1995).