Mathematical model of phosphatidylinositol-4,5-bisphosphate hydrolysis mediated by epidermal growth factor receptor generating diacylglycerol

Journal of Biotechnology

Volumn 124, Issue 3, 2006, Pages 574-591

  Su, Yong chun ^a   Lu, Di ^b   Tan, Xiao dan ^a   Dong, Ai rong ^a   Tian, Hui yong ^a   Luo, Shen qiu ^a   Deng, Qin kai ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

Diacylglycerol; Epidermal growth factor receptor; Phosphatidylinositol transfer protein; Phosphatidylinositol 4,5 bisphosphate; Phospholipase C 1

Indexed keywords

EPIDEMIOLOGY; GLYCEROL; HYDROLYSIS; MATHEMATICAL MODELS; METABOLISM; PHOSPHOLIPIDS; PROTEINS;

DIACYLGLYCEROL; EPIDERMAL GROWTH FACTOR RECEPTOR; PHOSPHATIDYLINOSITOL TRANSFER PROTEIN; PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE; PHOSPHOLIPASE C-Γ1;

PHOSPHATES;

CARRIER PROTEIN; DIACYLGLYCEROL; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHATIDYLINOSITOL TRANSFER PROTEIN; PHOSPHOLIPASE C GAMMA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; FIBROBLAST; HYDROLYSIS; MATHEMATICAL MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; COMPUTER SIMULATION; DIGLYCERIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDERMAL GROWTH FACTOR; HYDROLYSIS; MICE; MODELS, BIOLOGICAL; NIH 3T3 CELLS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 33745484954     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2006.01.029     Document Type: Article

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