Requirement for phospholipase C-γ/1 enzymatic activity in growth factor-induced mitogenesis

Molecular and Cellular Biology

Volumn 18, Issue 1, 1998, Pages 590-597

  Wang, Zhixiang ^a,c   Glück, Stefan ^a   Zhang, Lianfeng ^a   Moran, Michael F ^b  

^a UNIVERSITY OF OTTAWA   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c Division of Tumor Biology   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL; EPIDERMAL GROWTH FACTOR; GROWTH FACTOR; PHOSPHOLIPASE C; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CELL CYCLE; DNA SYNTHESIS; ENZYME ACTIVITY; GENE EXPRESSION; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA; FELIS CATUS;

EID: 2642593022     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.18.1.590     Document Type: Article

References (39)

1. Anderson, D., C. A. Koch, L. Grey, C. Ellis, M. F. Moran, and T. Pawson. 1990. Binding of SH2 domains of phospholipase Cγ1, GAP, and Src to activated growth factor receptors. Science 250:979-982.
2. Bar-Sagi, D., D. Rotin, A. Batzer, V. Mandiyan, and J. Schlessinger. 1993. SH3 domains direct cellular localization of signaling molecules. Cell 74:83-91.
3. Gilman, M. Z. 1988. The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP. Genes Dev. 2:394-402.
4. Gilman, M. Z., R. N. Wilson, and R. A. Weinberg. 1986. Multiple protein-binding sites in the 5′-flanking region regulate c-fos expression. Mol. Cell. Biol. 6:4305-4316.
5. Gout, I., R. Dhand, I. D. Hiles, M. J. Fry, G. Panayotou, P. Das, O. Truong, N. F. Totty, J. Hsuan, and G. W. Booker. 1993. The GTPase dynamin binds to and is activated by a subset of SH3 domains. Cell 75:25-36.
6. Graham, R., and M. Gilman. 1991. Distinct protein targets for signals acting at the c-fos serum response element. Science 251:189-192.
7. Hu, P., B. Margolis, E. Y. Skolnik, R. Lammers, A. Ullrich, and J. Schlessinger. 1992. Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors. Mol. Cell. Biol. 12:981-990.
8. Kim, H. K., J. W. Kim, A. Zilberstein, B. Margolis, J. G. Kim, J. Schlessinger, and S. G. Rhee. 1991. PDGF stimulation of inositol phospholipid hydrolysis requires PLC-γ1 phosphorylation on tyrosine residues 783 and 1254. Cell 65:43541.
9. Li, W., P. Hu, E. Y. Skolnik, A. Ullrich, and J. Schlessinger. 1992. The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors. Mol. Cell. Biol. 12:5824-5833.
10. Lowenstein, E. J., R. J. Daly, A. G. Batzer, W. Li, B. Margolis, R. Lammers, A. Ullrich, E. Y. Skolnik, D. Bar-Sagi, and J. Schlessinger. 1992. The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling. Cell 70:431-442.
11. Margolis, B., N. Li, A. Koch, M. Mohammadi, D. R. Hurwitz, A. Zilberstein, A. Ullrich, T. Pawson, and J. Schlessinger. 1990. The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-γ. EMBO J. 9:4375-4380.
12. Margolis, B., S. G. Rhee, S. Felder, M. Mervic, R. Lyall, A. Levitzki, A. Ullrich, A. Zilberstein, and J. Schlessinger. 1989 EGF induces tyrosine phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signaling. Cell 57:1101-1107.
13. Margolis, B., A. Zilberstein, C. Franks, S. Felder, S. Kremer, A. Ullrich, S. G. Rhee, K. Skorecki, and J. Schlessinger. 1990. Effect of phospholipase C-γ overexpression on PDGF-induced second messengers and mitogenesis. Science 248:607-610.
14. McGlade, C. J., C. Ellis, M. Reedijk, D. Anderson, G. Mbamalu, A. D. Reith, G. Panayotou, P. End, A. Bernstein, and A. Kazlauskas. 1992. SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors. Mol. Cell. Biol. 12:991-997.
15. Meisenhelder, J., and T. Hunter. 1992. The SH2/SH3 domain-containing protein Nck is recognized by certain anti-phospholipase C-γ1 monoclonal antibodies, and its phosphorylation on tyrosine is stimulated by platelet-derived growth factor and epidermal growth factor treatment. Mol. Cell. Biol. 12:5843-5856.
16. Meisenhelder, J., P. G. Suh, S. G. Rhee, and T. Hunter. 1989. Phospholipase C-γ is a substrate for the PDGF and EGF receptor protcin-tyrosine kinases in vivo and in vitro. Cell 57:1109-1122.
17. Mohammadi, M., C. A. Dionne, W. Li, N. Li, T. Spivak, A. M. Honegger, M. Jaye, and J. Schlessinger. 1992. Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis. Nature 358: 681-684.
18. Moran, M., C. Koch, D. Anderson, C. Ellis, L. England, G. Martin, and T. Pawson. 1990. Src homology region 2 domains direct protein-protein interactions in signal transduction. Proc. Natl. Acad. Sci. USA 87:8622-8626.
19. Nishizuka, Y. 1992. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258:607-614.
20. Park, D., and S. G. Rhee. 1992. Phosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP. Mol. Cell. Biol. 12:5816-5823.
21. Pawson, T. 1995. Protein modules and signalling networks. Nature 373:573-580.
22. Payne, G., L. A. Stolz, D. Pei, H. Band, S. E. Shoelson, and C. T. Walsh. 1994. The phosphopeptide binding specificity of Src family SH2 domains. Chem. Biol. 1:99-105.
23. Pelicci, G., L. Lanfrancone, F. Grignani, J. McGlade, F. Cavallo, G. Forni, I. Nicoletti, T. Pawson, and P. G. Pelicci. 1992. A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction. Cell 70:93-104.
24. 2+ flux but not mitogenesis. Nature 358:678-681.
25. Roche, S., J. McGlade, M. Jones, G. D. Gish, T. Pawson, and S. A. Courtneidge. 1996. Requirement of phospholipase C-γ, the tyrosine phosphatase Syp and the adaptor proteins Shc and Nck for PDGF-induced DNA synthesis: evidence for the existence of Ras-dependent and Ras-independent pathways. EMBO J. 15:4940-4948.
26. Ronnstrand, L., S. Mori, A. K. Arridsson, A. Eriksson, C. Wernstedt, U. Hellman, L. Claesson-Welsh, and C. H. Heldin. 1992. Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-γ. EMBO J. 11:3911-3919.
27. Rotin, D., B. Margolis, M. Mohammadi, R. J. Daly, G. Daum, N. Li, E. H. Fischer, W. H. Burgess, A. Ullrich, and J. Schlessinger. 1992. SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase C-γ. EMBO J. 11:559-567.
28. Schlessinger, J., and A. Ullrich. 1992. Growth factor signaling by receptor tyrosine kinases. Neuron 9:383-391.
29. Seedorf, K., G. Kostka, R. Lammers, P. Bashkin, R. Daly, W. H. Burgess, A. M. van der Bliek, J. Schlessinger, and A. Ullrich. 1994. Dynamin binds to SH3 domains of phospholipase Cγ and GRB-2. J. Biol. Chem. 269:16009-16014.
30. Shaw, P. E., H. Schroter, and A. Nordheim. 1989. The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoter. Cell 56:563-572.
31. Smith, M. R., Y. L. Liu, H. Kim, S. G. Rhee, and H. F. Kung. 1990. Inhibition of serum- and ras-stimulated DNA synthesis by antibodies to phospholipase C. Science 247:1074-1077.
32. Soler, C., L. Beguinot, and G. Carpenter. 1994. Individual epidermal growth factor receptor autophosphorylation sites do not stringently define association motifs for several SH2-containing proteins. J. Biol. Chem. 269:12320-12324.
33. Songyang, Z., S. E. Shoelson, M. Chaudhuri, G. Gish, T. Pawson, W. G. Haser, F. King, T. Roberts, S. Ratnofsky, and R. J. Lechleider. 1993. SH2 domains recognize specific phosphopeptide sequences. Cell 72:767-778.
34. Valinus, M., and A. Kazlauskas. 1993. Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal. Cell 73:321-334.
35. Wahl, M., and G. Carpenter. 1991. Selective phospholipase C activation. Bioessays 13:107-113.
36. Wahl, M. I., T. O. Daniel, and G. Carpenter. 1988. Antiphosphotyrosine recovery of phospholipase C activity after EGF treatment of A-431 cells. Science 241:968-970.
37. Wang, Z. Unpublished observations.
38. Wang, Z., and M. F. Moran. 1996. Requirement for the adapter protein GRB2 in EGF receptor endocytosis. Science 272:1935-1939.
39. Wang, Z., P. S. Tung, and M. F. Moran. 1996. Association of p120 ras GAP with endocytic components and colocalization with epidermal growth factor (EGF) receptor in response to EGF stimulation. Cell Growth Differ. 7:123-133.