Modeling and computational analysis of EGF receptor-mediated cell communication in Drosophila oogenesis

Development

Volumn 129, Issue 11, 2002, Pages 2577-2589

  Shvartsman, Stanislav Y ^a   Muratov, Cyrill B ^a   Lauffenburger, Douglas A ^a  

^a Princeton University   (United States)

Author keywords

Autocrine loops; Drosophila; EGFR; Mathematical modeling

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR;

ANIMAL CELL; AUTOCRINE EFFECT; BIOCHEMISTRY; CELL COMMUNICATION; CELL TRANSPORT; CONTROLLED STUDY; DROSOPHILA; EGG SHELL; FEEDBACK SYSTEM; GENETIC ANALYSIS; GENETIC MANIPULATION; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MICROMORPHOLOGY; NONHUMAN; OOCYTE DEVELOPMENT; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; BODY PATTERNING; CELL COMMUNICATION; DROSOPHILA; EGG SHELL; FEMALE; MODELS, BIOLOGICAL; MODELS, THEORETICAL; OOGENESIS; PHENOTYPE; RECEPTOR, EPIDERMAL GROWTH FACTOR;

ANIMALIA; ARACHNIDA; HEXAPODA;

EID: 0036333324     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (75)

1. Rhomboid and Star facilitate presentation and processing of the Drosophila TGF-alpha homolog Spitz
2. Regulation of cell number by MAPK-dependent control of apoptosis. A mechanism for trophic survival signaling
3. Signalling by the Drosophila epidermal growth factor receptor is required for the specification and diversification of embryonic muscle progenitors
4. Control of EGF receptor signalling: Lessons from fruitflies
5. Integration of epithelial patterning and morphogenesis in Drosophila oogenesis
6. Numerical analysis and control of bifurcation problems. (II) Bifurcations in infinite dimensions
7. Expression and action of transforming growth factor alpha in normal ovarian surface epithelium and ovarian cancer
8. Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible
9. Cell determination strategies in the Drosophila eye
10. Feedback control of intercellular signalling in development
11. Okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis
12. Mechanism of activation of the Drosophila EGF Receptor by the TGFalpha ligand Gurken during oogenesis
13. Argos transcription is induced by the Drosophila EGF receptor pathway to form an inhibitory feedback loop
14. Ras pathway specificity is determined by the integration of multiple signal-activated and tissue-restricted transcription factors
15. Morphogenesis
16. Function of the Drosophila TGF-alpha homolog Spitz is controlled by Star and interacts directly with Star
17. Drosophila Pin1 prolyl isomerase Dodo is a MAP kinase signal responder during oogenesis
18. Sequence and functional properties of ETS genes in the model organism Drosophila
19. A First Course in the Numerical Analysis of Differential Equations
20. The interaction between the Drosophila secreted protein argos and the epidermal growth factor receptor inhibits dimerization of the receptor and binding of secreted protein spitz
21. The ERK-1/2 signaling pathway is involved in the stimulation of branching morphogenesis of fetal mouse submandibular glands by EGF
22. Autosolitons
23. Regulated intracellular ligand transport and proteolysis regulate egf receptor activation in Drosophila
24. Experimental observation of self-replicationg spots in a reaction-diffusion system
25. Down-regulation of transcription factor CF2 by Drosophila Ras/MAP kinase signaling in oogenesis: Cytoplasmic retention and degradation
26. A temporal switch in DER signaling controls the specification and differentiation of veins and interveins in the Drosophila wing
27. Pattern formation by local self-activation and lateral self-inhibition
28. Genetic control of branching morphogenesis
29. Pointed, an ETS domain transcription factor, negatively regulates the EGF receptor pathway in Drosophila oogenesis
30. General theory of instabilities for patterns with sharp interfaces in reaction-diffusion systems
31. Endocytosis in Drosophila: Progress, possibilities, prognostications
32. The Drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodesa TGF alpha-like protein
33. Dorsoventral axis formation in Drosophila depends on the correct dosage of the gene gurken
34. The Drosophila TGF-alpha-like protein: Expression and cellular localization during Drosophila oogenesis
35. EGF receptor signaling in Drosophila oogenesis
36. D-cbl, a negative regulator of the Egfr pathway, is required for dorsoventral patterning in Drosophila oogenesis
37. Selection for spiral waves in the social amoebae Dictyostelium
38. Local Gurken signaling and dynamic MAPK activation during Drosophila oogenesis
39. Combined activities of Gurken and Decapentaplegic specify dorsal chorion structures of the Drosophila egg
40. Negative feedback mechanisms and their roles during pattern formation
41. There must be 50 ways rule the signal: The case of the Drosophila EGF receptor
42. The transmembrane region of Gurken is not required for biological activity, but is necessary for transport to the oocyte membrane in Drosophila
43. Ectopic activation of torpedo/Egfr, a Drosophila receptor tyrosine kinase, dorsalizes both the eggshell and the embryo
44. Sprouty, a general inhibitor of receptor tyrosine kinase signaling
45. Stripe forming architecture of the gap gene system
46. Axis formation during Drosophila oogenesis
47. Binuclear Drosophila oocytes: Consequences and implications for dorsal-ventral patterning in oogenesis and embryogenesis
48. Spatially localized rhomboid is required for establishing the dorsal-ventral axis in Drosophila oogenesis
49. The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis
50. Sequential activation of the EGF receptor pathway during Drosophila oogenesis establishes the dorsoventral axis
51. Germ line and soma cooperate during oogenesis to establish the dorsoventral pattern of the eggshell and embryo in Drosophila melanogaster
52. A thousand and one roles for the Drosophila EGF receptor
53. Inhibition of Drosophila EGF receptor activation by the secreted protein
54. Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination
55. Spatial range of autocrine signaling: Modeling and computational analysis
56. Autocrine loops with positive feedback enable context-dependent cell signaling
57. Developmental genetics of oogenesis
58. Twin Peaks:Spitz and Argos star in patterning of the Drosophila egg
59. Shaping morphogen gradients
60. Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz
61. The chemical basis of morphogenesis
62. Involvement of heparin-binding EGF-like growth factor and its processing by metalloproteinases in early epithelial morphogenesis of the submandibular gland
63. Versatility in signaling: Multiple responses to EGF receptor activation during Drosophila oogenesis
64. Insertion of argos sequences into the B-Loop of epidermal growth factor results in a low-affinity ligand with strong agonistic activity
65. Evidence that Argos is an antagonistic ligand of the EGF receptor
66. The segment polarity network is a robust developmental module
67. Morphogenesis of the eggshell in Drosophila
68. An autoregulatory cascade of EGF receptor signaling patterns the Drosophila egg
69. Tissue-specific regulation of vein/EGF receptor signaling in Drosophila
70. Signaling through the stromal epidermal growth factor receptor is necessary for mammary ductal development
71. Regulation of receptor tyrosine kinase signaling by endocytic trafficking
72. Principles of Development
73. Genomic cis-regulatory logic: Experimental and computational analysis of a sea urchin gene
74. Misexpression of argos, an inhibitor of EGFR signaling in oogenesis, leads to the production of bicephalic, ventralized, and lateralized Drosophila melanogaster eggs