Impaired endotoxin tolerance induction in patients with familial Mediterranean fever

Pathobiology

Volumn 73, Issue 1, 2006, Pages 26-39

  Davtyan, Tigran K ^a   Hakopyan, Gagik S ^b   Avetisyan, Samvel A ^b   Mkrtchyan, Nana R ^c  

^a Armenicum Research Centre Yerevan   (Armenia)

^b YEREVAN STATE MEDICAL UNIVERSITY   (Armenia)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Endotoxin tolerance; Familial Mediterranean fever; Lipopolysaccharides; Proinflammatory activation

Indexed keywords

COLCHICINE; CYTOKINE; ENDOTOXIN; INTERLEUKIN 4; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

ADULT; AMYLOIDOSIS; ARTICLE; BEHCET DISEASE; CHRONIC INFLAMMATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FAMILIAL MEDITERRANEAN FEVER; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKOCYTE ACTIVATION; MALE; MONOCYTE; NEUTROPHIL; PHAGOCYTOSIS; PRIORITY JOURNAL; REMISSION; RESPIRATORY BURST;

ADOLESCENT; ADULT; ANTIGENS, CD11A; ANTIGENS, CD18; BEHCET SYNDROME; CYTOKINES; ENDOTOXINS; FAMILIAL MEDITERRANEAN FEVER; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNE TOLERANCE; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MALE; MONOCYTES; NEUTROPHIL ACTIVATION; NEUTROPHILS; PHAGOCYTOSIS; RESPIRATORY BURST;

BACTERIA (MICROORGANISMS);

EID: 33745476104     PISSN: 10152008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000093089     Document Type: Article

References (56)

1. Ben-Chetrit E, Levy M: Familial Mediterranean fever. Lancet 1998;35:659-664.
2. Orbach H, Ben-Chetrit E: Familial Mediterranean fever. Minerva Med 2001;92:421-430.
3. Korkmaz C, Ozdogan H, Kasapcopur O, Yazici H: Acute phase response in familial Mediterranean fever. Ann Rheum Dis 2002;61:79-81.
4. Sohar E, Gafni J, Pras M, Heller H: Familial Mediterranean fever: a survey of 470 cases and review of the literature. Am J Med 1967;43:227-253.
5. Shohat M, Danon YL, Rotter JI: Familial Mediterranean fever: analysis of inheritance and current linkage data. Am J Med Genet 1992;44:183-187.
6. International FMF Consortium: Ancient missense mutations in a new member of the Ro-Ret gene family are likely to cause familial Mediterranean fever. Cell 1997;90:797-807.
7. French FMF Consortium: A candidate gene for familial Mediterranean fever. Nat Genet 1997;17:25-31.
8. Centola M, Wood G, Frucht DM, Galon J, Aringer M, Farrell C, Kingma DW, Horwitz ME, Mansfield E, Holland SM, O'Shea JJ, Rosenberg HE, Malech HL, Kastner DL: The gene for familial Mediterranean fever, MEFV, is expressed in early leukocyte development and is regulated in response to inflammatory mediators. Blood 2000;95:3223-3231.
9. Papin S, Cazeneuve C, Duguesony P, Jeru I, Sahai D, Amselem S: The tumor necrosis factor α-dependent activation of the human Mediterranean fever (MEFV) promoter is mediated by a synergistic interaction between C/EBPβ and NFκB p65. J Biol Chem 2003;278:48839-48847.
10. Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A: PAAD - a new domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci 2001;26:85-87.
11. Staub E, Dahl E, Rosenthal A: The DAPIN family: a novel domain links apoptotic and interferon response proteins. Trends Biochem Sci 2001;26:83-85.
12. Richards N, Schaner P, Diaz A, Stuckey J, Shelden E, Wadhwa A, Gumucio DL: Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis. J Biol Chem 2001;276:39320-39329.
13. Stehlik C, Fiorentino L, Dorfleutner A, Bruey JM, Ariza EM, Sagara J, Reed JC: The PAAD/PYRIN family protein ASC is a dual regulator of a conserved step in nuclear factor κ activation pathways. J Exp Med 2002;196:1605-1615.
14. Stehlik C, Lee SH, Dorfleutner A, Stassinopoulos A, Sagara J, Reed JC: Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase-1 activation. J Immunol 2003;171:6154-6163.
15. Dowds TA, Masumoto J, Chen FF, Ogura Y, Inohara N, Nunez G: Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product. Biochem Biophys Res Commun 2003;302:575-580.
16. Dowds TA, Masumoto J, Zhu L, Inohara N, Nunez G: Cryopyrin-induced IL-1β secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC. J Biol Chem 2004;279:21924-21928.
17. Chae JJ, Komarov HD, Cheng J, Wood G, Raben N, Liu PP, Kastner DL: Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. Mol Cell 2003;7:591-604.
18. Stehlik C, Reed JC: The pyrin connection: Novel players in innate immunity and inflammation. J Exp Med 2004;200:551-558.
19. Gumucio DL, Diaz A, Schaner PAB, Richards N, Babcock CBS, Sehaller MBS, Cesena TBS: Fire and ICE: the role of pyrin domain-containing proteins in inflammation and apoptosis. Clin Exp Rheumatol 2002;20:S45-S53.
20. Medzhitov R, Janeway CA: Decoding the patterns of self and nonself by the innate immune system. Science 2002;296:298-300.
21. Hajishengallis G, Martin M, Schifferle RE, Genco RJ: Counteracting interactions between lipopolysaccharide molecules with differential activation of Toll-like receptors. Infect Immunol 2002;70:6658-6664.
22. Deiters U, Gumenscheimer M, Galanos C, Mühlradt PF: Toll-like receptor 2- and 6-mediated macrophage-activating lipopeptide 2 induces lipopolysaccharide (LPS) cross tolerance in mice, which results in protection from tumour necrosis factor alpha but in only partial protection from lethal LPS doses. Infect Immunol 2003;71:4456-4462.
23. Varma TK, Toliver-Kinsky TE, Lin CY, Koutrouvelis AP, Nicholas JE, Sherwood ER: Cellular mechanisms that cause suppressed gamma interferon secretion in endotoxin-tolerant mice. Infect Immunol 2001;69:5249-5263.
24. Mosser DM: The many faces of macrophage activation. J Leukoc Biol 2003;73:209-212
25. Livneh A, Langevitz P, Zemer D, Zaks N, Kees S, Lidar T: Criteria for a diagnosis of familial Mediterranean fever. Arthritis Rheum 1997;40:1879-1885.
26. International Study Group for Behçet's Disease: Criteria for diagnosis of Behçet's disease. Lancet 1990;335:1078-1080.
27. Dobmeyer TS, Raffel B, Dobmeyer JM, Findhammer S, Klein SA, Kabelitz D, Hoelzer D, Helm EB: Decreased function of monocytes and granulocytes during HIV-1 infection correlates with CD4 cell counts. Eur J Med Res 1995;1:9-15.
28. Rothe G, Oser A, Valet G: Dihydrorhodamine 123: a new flow cytometric indicator for respiratory burst activity in neutrophil granulocytes. Naturwissenschaften 1988;75:354-355.
29. Medvedev AE, Lentschat A, Wahl LM, Golenbock DT, Vogel SN: Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor associated kinase 1 activation in endotoxin-tolerant cells. J Immunol 2002;169:5209-5216.
30. Wehrle-Haller B, Imhof BA: Integrin-dependent pathologies. J Pathol 2003;200:253-260.
31. Wright SD, Jong MTC: Adhesion-promoting receptors on human macrophages recognize Escherichia coli by binding to lipopolysaccharide. J Exp Med 1986;164:1876-1885.
32. Emoto M, Emoto Y, Brinkmann V, Milyamoto M, Yoshizawa I, Stäber M, van Rooijen N, Hamann A, Kaufmann SHE: Increased resistance of LFA-1-deficient mice to lipopolysaccharide-induced shock/liver injury in the presence of TNF-α and IL-12 is mediated by IL-10: a novel role for LFA-1 in the regulation of the proinflammatory and anti-inflammatory cytokine balance. J Immunol 2003;171:584-593.
33. Mansfield E, Chae JJ, Komarov HD, Brotz TM, Frucht DM, Aksentijevich I, Kastner DL: The familial Mediterranean fever protein, pyrin, associates with microtubules and colocalizes with actin filaments. Blood 2001;98:851-859.
34. Cazeneuve C, Papin S, Jeru I, Duquesnoy P, Amselem S: Subcellular localisation of marenostrin/pyrin isoforms carrying the most common mutation involved in familial Mediterranean fever in the presence or absence of its binding partner ASC. J Med Genet 2004;41:24-31.
35. Chae JJ, Centola M, Aksentijevich I, Dutra A, Tran M, Wood G, Nagaraju K, Kingma DW, Liu PP, Kastner DL: Isolation, genomic organization, and expression analysis of the mouse and rat homologs of MEFV, the gene for familial Mediterranean fever. Mamm Genome 2000;11:428-435.
36. Schaner P, Richards N, Wadhawa A, Aksentijevich I, Kastner DL, Tucker P, Gumucio D: Episodic evolution of pyrin in primates: human mutations recapitulate ancestral amino acid states. Nat Genet 2001;27:318-321.
37. Wells CA, Ravasi T, Faulkner G, Carinci P, Okazaki Y, Hayashizaki Y, Sweet MJ, Wainwright BJ, Hume DA: Genetic control of the innate immune response. BMC Immunol 2003;4:5.
38. Wells CA, Ravasi T, Hume DA: Inflammation suppressor genes: please switch out all the lights. J Leukoc Biol 2005;78:9-13.
39. Bar-Eli M, Levy M, Ehrenfeld M, Eliakim M, Gallily R: Phagocyte function in familial Mediterranean fever. Adv Exp Med Biol 1979;121:341-350.
40. Bar-Eli M, Terrino MC, Peters RS, Schwabe AA: A neutrophil lysozyme leak in patients with familial Mediterranean fever. Am J Hematol 1981;11:387-395.
41. Territo MC, Peters RS, Cline MJ: Leukocyte function in FMF. Am J Hematol 1976;1:341-350.
42. Keskin G, Inal A, Sengul A, Cindoruk M, Haznedaroglu S, Duranay M, Songur Y: Phagocytic activity in familial Mediterranean fever. Yonsei Med J 2000;41:441-444.
43. Kluve-Beckerman B, Manaloor J, Liepnieks JJ: Binding, trafficking and accumulation of serum amyloid A in peritoneal macrophages. Scand J Immunol 2001;53:393-400.
44. Anton PA, Targan SR, Vigna SR, Durham M, Schwabe AD, Shanahan F: Enhanced neutrophil chemiluminescence in familial Mediterranean fever. J Clin Immunol 1988;8:148-156.
45. Bar-Eli M, Ehrenfeld M, Levy M, Gallily R, Eliakim M: Leukocyte chemotaxis in recurrent polyserositis (familial Mediterranean fever). Am J Med Sci 1981;281:15-18.
46. - production by neutrophils. Hum Genet 1997;101:238-242.
47. Mege JL, Dilsen N, Sanguedolce V, Gul A, Bongard P, Roux H, Ocal L, Inac M, Capo C: Overproduction of monocyte derived TNF, interleukin (IL) 6, IL-8 and increased neutrophil superoxide generation in Behçet's disease: a comparative study with familial Mediterranean fever and healthy subjects. J Rheumatol 1993;20:1544-1549.
48. Baykal Y, Saglam K, Yilmaz MI, Taslipinar A, Akinci SB, Inal A: Serum sIL-2r, IL-6, IL-10 and TNF-α level in familial Mediterranean fever patients. Clin Rheumatol 2003;22:99-101.
49. Bagci S, Toy B, Tuzun A, Ates Y, Asian M, Inal A, Gulsen M, Karaeren N, Dagalap K: Continuity of cytokine activation in patients with familial Mediterranean fever. Clin Rheumatol 2004;23:333-337.
50. Loke P, Nair MG, Parkinson J, Guiliano D, Blaxter M, Allen JE: IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype. BMC Immunol 2002;3:7.
51. Yamada T, Wada A, Itoh K, Igari J: Serum amyloid A secretion from monocytic leukaemia cell line THP-1 and cultured human peripheral monocytes. Scand J Immunol 2000;52:7-12.
52. Tzachanis D, Berzovskaya A, Nadler LM, Boussiotis VA: Blockade of B7/CD28 in mixed lymphocyte reaction cultures results in the generation of alternatively activated macrophages, which suppress T-cell responses. Blood 2002;99:1465-1473.
53. Jacinto R, Hartung T, McCall C, Li L: Lipopolysaccharide- and lipoteichoic acid-induced tolerance and cross-tolerance: distinct alteration in IL-1 receptor-associated kinase. J Immunol 2002;168:6136-6141.
54. Sato S, Takeuchi O, Fujita T, Tomizawa H, Takeda K, Akira S: A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways. Int Immunol 2002;14:783-791.
55. Musabak U, Sengul A, Oktenli C, Pay S, Yesilova Z, Kenar L, Sanisoglu SY, Inal A, Tuzun A, Erdil A, Bagci S: Does immune activation continue during an attack-free period in familial Mediterranean fever? Clin Exp Immunol 2004;138:526-533.
56. Zemer D, Pras M, Sohar E, Modan M, Cabili S, Gafni J: Colchicine in the prevention and treatment of the amyloidosis of familial Mediterranean fever. N Eng J Med 1986;314:1001-1005.