Stabilisation of transition states prior to and following eudesmane cation in aristolochene synthase

Organic and Biomolecular Chemistry

Volumn 4, Issue 13, 2006, Pages 2563-2567

  Forcat, Silvia ^a   Allemann, Rudolf K ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HYDRIDES; MUTAGENESIS; PHOSPHATES; POSITIVE IONS;

ARISTOLOCHENE SYNTHASE; EUDESMANE CATION; FARNESYLPYROPHOSPHATE (FPP); TRANSITION STATES;

ENZYMES;

ARISTOLOCHENE SYNTHASE; CATION; EUDESMANE; ISOMERASE; PRIMER DNA; SESQUITERPENE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; NUCLEOTIDE SEQUENCE; PENICILLIUM; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

BASE SEQUENCE; CATIONS; CRYSTALLOGRAPHY, X-RAY; DNA PRIMERS; ISOMERASES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PENICILLIUM; SESQUITERPENES, EUDESMANE;

PENICILLIUM ROQUEFORTII;

EID: 33745459252     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b604147g     Document Type: Article

References (19)

1. M. J. Rynkiewicz D. E. Cane D. W. Christianson Proc. Natl. Acad. Sci. USA 2001 98 13543 13548
2. C. A. Lesburg J. M. Caruthers C. M. Paschall D. W. Christianson Curr. Opin. Struct. Biol. 1998 8 695 703
3. J. Bohlmann G. Meyer-Gauen R. Croteau Proc. Natl. Acad. Sci. USA 1998 95 4126 4133
4. M. J. Rynkiewicz D. E. Cane D. W. Christianson Biochemistry 2002 41 1732 1741
5. C. A. Lesburg G. Zhai D. E. Cane D. W. Christianson Science 1997 277 1820 1824
6. C. M. Starks K. Back J. Chappell J. P. Noel Science 1997 277 1815 1820
7. J. M. Caruthers I. Kang M. J. Rynkiewicz D. E. Cane D. W. Christianson J. Biol. Chem. 2000 275 25533 25539
8. A. Deligeorgopoulou R. K. Allemann Biochemistry 2003 42 7741 7747
9. R. H. Proctor T. M. Hohn J. Biol. Chem. 1993 268 4543 4548
10. B. Felicetti D. E. Cane J. Am. Chem. Soc. 2004 126 7212 7221
11. D. E. Cane Y. S. Tsantrizos J. Am. Chem. Soc. 1996 118 10037 10040
12. M. J. Calvert P. R. Ashton R. K. Allemann J. Am. Chem. Soc. 2002 124 11636 11641
13. M. J. Calvert S. E. Taylor R. K. Allemann Chem. Commun. 2002 2384 2385
14. A. Deligeorgopoulou S. E. Taylor S. Forcat R. K. Allemann Chem. Commun. 2003 2162 2163
15. D. E. Cane P. C. Prabhakaran J. S. Oliver D. B. McIlwaine J. Am. Chem. Soc. 1990 112 3209 3210
16. S. Forcat R. K. Allemann Chem. Commun. 2004 2094 2095
17. D. E. Cane P. C. Prabhakaran J. S. Oliver D. B. Mc Ilwaine J. Am. Chem. Soc. 1990 112 3209 3210
18. J.-W. d. Kraker M. C. R. Franssen A. d. Groot W. A. Koenig H. J. Bowmeester Plant Physiol. 1998 117 1381 1392
19. V. J. Davisson A. B. Woodside T. R. Neal K. E. Stremler M. Muehlbacher C. D. Poulter J. Org. Chem. 1986 51 4768 4779