Heavy use of prophylactic antibiotics in aquaculture: A growing problem for human and animal health and for the environment

Environmental Microbiology

Volumn 8, Issue 7, 2006, Pages 1137-1144

  Cabello, Felipe C ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; DRUG RESIDUE;

ANIMAL; ANTIBIOTIC PROPHYLAXIS; ANTIBIOTIC RESISTANCE; AQUACULTURE; BACTERIUM; DRUG EFFECT; FISH; FOOD ALLERGY; GENETICS; HUMAN; METHODOLOGY; MICROBIOLOGY; SHORT SURVEY; STANDARD; UTILIZATION REVIEW;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIBIOTIC PROPHYLAXIS; AQUACULTURE; BACTERIA; DRUG RESIDUES; DRUG RESISTANCE, BACTERIAL; ENVIRONMENTAL MICROBIOLOGY; FISHES; FOOD HYPERSENSITIVITY; HUMANS; WATER MICROBIOLOGY;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 33745146852     PISSN: 14622912     EISSN: 14622920     Source Type: Journal    
DOI: 10.1111/j.1462-2920.2006.01054.x     Document Type: Short Survey

References (93)

1. Agerso Y. Guardabassi L. ( 2005) Identification of Tet 39, a novel class of tetracycline resistance determinant in Acinetobacter spp. of environmental and clinical origin. J Antimicrob Chemother 55 : 566 569.
2. Alcaide E. Blasco M.-D. Esteve C. ( 2005) Occurrence of drug-resistant bacteria in two European eel farms. Appl Environ Microbiol 71 : 3348 3350.
3. Alderman D.J. Hastings T.S. ( 1998) Antibiotic use in aquaculture: development of antibiotic resistance - potential for consumer health risks. Int J Food Sci Technol 33 : 139 155.
4. Anderson A.D. Nelson J.M. Rossiter S. Angulo F.J. ( 2003) Public health consequences of use of antimicrobial agents in food animals in the United States. Microb Drug Resist 9 : 373 379.
5. Angulo F.J. ( 2000) Antimicrobial agents in aquaculture: potential impact on health. APUA Newsletter 18 : 1 6.
6. Angulo F.J. Griffin P.M. ( 2000) Changes in antimicrobial resistance in Salmonella enterica serovar Typhimurium. Emerg Infect Dis 6 : 436 438.
7. Angulo F.J. Nargund V.N. Chiller T.C. ( 2004) Evidence of an association between use of anti-microbial agents in food animals and anti-microbial resistance among bacteria isolated from humans and the human health consequences of such resistance. J Vet Med 51 : 374 379.
8. Bakken J.S. ( 2004) The fluoroquinolones: how long will their utility last? Scand J Infect Dis 36 : 85 92.
9. Balaban N.Q. Merrin J. Chait R. Kowalik L. Leibler S. ( 2004) Bacterial persistence as a phenotypic switch. Science 305 : 1622 1625.
10. Barton B.A. Iwama G.K. ( 1991) Physiological changes in fish from stress in aquaculture with emphasis on the response and effects of corticosteroids. Annu Rev Fish Dis 1 : 3 26.
11. Beaber J.W. Hochhut B. Waldor M.K. ( 2004) SOS response promotes horizontal dissemination of antibiotic resistance genes. Nature 427 : 72 74.
12. Bolton L.F. Kelley L.C. Lee M.D. Fedorka-Cray P.J. Maurer J.J. ( 1999) Detection of multidrug-resistant Salmonella enterica serotype Typhimurium DT104 based on a gene which confers cross-resistance to florfenicol and chloramphenicol. J Clin Microbiol 37 : 1348 1351.
13. Boxall A.B. Fogg L.A. Blackwell P.A. Kay P. Pemberton E.J. Croxford A. ( 2004) Veterinary medicines in the environment. Rev Environ Contam Toxicol 180 : 1 91.
14. Boyd D. Peters G.A. Cloeckaert A. Boumedine K.S. Chaslus-Dancla E. Imberechts H. Mulvey M.R. ( 2001) Complete nucleotide sequence of a 43-kilobase genomic island associated with the multidrug resistance region of Salmonella enterica serovar Typhimurium DT104 and its identification in phage type DT120 and serovar Agona. J Bacteriol 183 : 5725 5732.
15. Bravo S. Dolz H. Silva M.T. Lagos C. Millanao A. Urbina M. ( 2005) Informe Final. Diagnostico del uso de fármacos y otros productos químicos en la acuicultura. Universidad Austral de Chile. Facultad de Pesquerias y Oceanografia, Instituto de Acuicultura. Casilla 1327. Puerto Montt, Chile. Proyecto No. 2003-28.
16. Briggs C.E. Fratamico P.M. ( 1999) Molecular characterization of an antibiotic resistance gene cluster of Salmonella Typhimurium DT104. Antimicrob Agents Chemother 43 : 846 849.
17. Burrus V. Waldor M.K. ( 2003) Control of SXT integration and excision. J Bacteriol 185 : 5045 5054.
18. Bushman F. ( 2002a) Conjugation, transposition, and antibiotic resistance. In Lateral DNA Transfer. Mechanisms and Consequences. Cold Spring Harbor, NY, USA : Cold Spring Harbor Laboratory Press, pp. 27 72.
19. Bushman F. ( 2002b) Phage transduction and bacterial pathogenesis. In Lateral DNA Transfer. Mechanisms and Consequences. Cold Spring Harbor, NY, USA : Cold Spring Harbor Laboratory Press, pp. 73 128.
20. Cabello F.C. ( 2003) Antibiotics and aquaculture. An analysis of their potential impact upon the environment, human and animal health in Chile. Fundacion Terram. Analisis de Politicas Publicas No. 17, pp. 1-16. URL http://www.terram.cl/docs/App17_Antibioticos_y_Acuicultura.pdf
21. Cabello F.C. ( 2004) Antibiotics and aquaculture in Chile: implications for human and animal health. Rev Med Chil 132 : 1001 1006.
22. Casas C. Anderson E.C. Ojo K.K. Keith I. Whelan D. Rainnie D. Roberts M.C. ( 2005) Characterization of pRAS1-like plasmids from atypical North American psychrophilic Aeromonas salmonicida. FEMS Microbiol Lett 242 : 59 63.
23. Clark G.M. Kaufmann A.F. Gangarosa E.J. ( 1973) Epidemiology of an international outbreak of Salmonella Agona. Lancet 2 : 490 493.
24. Coyne R. Hiney M. Smith P. ( 1997) Transient presence of oxytetracycline in blue mussels (Mytilus edulis) following its therapeutic use at a marine Atlantic salmon farm. Aquaculture 149 : 175 181.
25. Davies J.E. Roberts M.C. Levy S.B. Miller G.H. O'Brien T.F. Tenover F.C. ( eds 1999) Antimicrobial resistance: An ecological perspective A report from the American Academy of Microbiology) Colloquium held 16-18 July, 1999, San Juan, Puerto Rico. Washington, DC, USA : American Academy of Microbiology.
26. Davison J. ( 1999) Genetic exchange between bacteria in the environment. Plasmid 42 : 73 91.
27. Fuhrman J.A. ( 1999) Marine viruses and their biogeochemical and ecological effects. Nature 399 : 541 548.
28. Furushita M. Maeda T. Akagi H. Ohta M. Shiba T. ( 2005) Analysis of plasmids that can transfer antibiotic resistance genes from fish farm bacteria to clinical bacteria. In Abstracts, Joint Meeting of the 3 Divisions of the International Union of Microbiological Societies 2005. International Congress of Bacteriology and Applied Microbiology, B-1162. 23-28 July 2005, San Fransisco, CA, USA.
29. Goldburg R. Naylor R. ( 2005) Future seascapes, fishing, and fish farming. Front Ecol Environ 3 : 21 28.
30. Goldburg R.J. Elliott M.S. Naylor R.L. ( 2001) Marine Aquaculture in the United States: Environmental Impacts and Policy Options. Arlington, VA, USA : PEW Oceans Commission.
31. Gonzalez-Escalona N. Cachicas V. Acevedo C. Rioseco M.L. Vergara J.A. Cabello F., et al. ( 2005) Vibrio parahaemolyticus diarrhea, Chile, 1998 and 2004. Emerg Infect Dis 11 : 129 131.
32. Gorbach S.L. ( 2001) Antimicrobial use in animal feed - time to stop. N Engl J Med 345 : 1202 1203.
33. Grave K. Markestad A. Bangen M. ( 1996) Comparison in prescribing patterns of antibacterial drugs in salmonid farming in Norway during the periods 1980-1988 and 1989-1994. J Vet Pharmacol Therap 19 : 184 191.
34. Grave K. Lingaas E. Bangen M. Rønning M. ( 1999) Surveillance of the overall consumption of antibacterial drugs in humans, domestic animals and farmed fish in Norway in 1992 and 1996. J Antimicrob Chemother 43 : 243 252.
35. Greenlees K.J. ( 2003) Animal drug human food safety toxicology and antimicrobial resistance - the square peg. Int J Toxicol 22 : 131 134.
36. Guardabassi L. Dalsgaard A. Raffatellu M. Olsen J.E. ( 2000) Increase in the prevalence of oxolinic acid resistant Acinetobacter spp. observed in a stream receiving the effluent from a freshwater trout farm following the treatment with oxolinic acid-medicated feed. Aquaculture 188 : 205 218.
37. Hansen P.K. Lunestad B.T. Samuelsen O.B. ( 1992) Effects of oxytetracycline, oxolinic acid, and flumequine on bacteria in an artificial fish farm sediment. Can J Microbiol 39 : 1307 1312.
38. Hastings P.J. Rosenberg S.M. Slack A. ( 2004) Antibiotic-induced lateral transfer of antibiotic resistance. Trends Microbiol 12 : 401 404.
39. Haya K. Burridge L.E. Chang B.D. ( 2000) Environmental impact of chemical wastes produced by the salmon aquaculture industry. ICES J Mar Sci 58 : 492 496.
40. Hektoen H. Berge J.A. Hormazabal V. Yndestad M. ( 1995) Persistence of antibacterial agents in marine sediments. Aquaculture 133 : 175 184.
41. Hernandez G.C. Ulloa P.J. Vergara O.J.A. Espejo T.R. Cabello C.F. ( 2005) Vibrio parahaemolyticus infections and algal intoxications as emergent public health problems in Chile. Rev Med Chile 133 : 1081 1088.
42. Holten Lützhøft H.-C. Halling-Sørensen B. Jørgensen S.E. ( 1999) Algal toxicity of antibacterial agents applied in Danish fish farming. Arch Environ Contam Toxicol 36 : 1 6.
43. Hunter-Cevera J. Karl D. Buckley M. (eds) ( 2005) Marine microbial diversity: the key to earth's habitability. (A report from the American Academy of Microbiology) Colloquium held 8-10 April 2005, San Francisco, CA, USA: Marine Microbial Diversity. Washington, DC, USA : American Academy of Microbiology.
44. Huys G. Rhodes G. McGann P. Denys R. Pickup R. Hiney M., et al. ( 2000) Characterization of oxytetracycline-resistant heterotrophic bacteria originating from hospital and freshwater fishfarm environments in England and Ireland. Syst Appl Microbiol 23 : 599 606.
45. Jacoby G.A. ( 2005) Mechanisms of resistance to quinolones. Clin Infect Dis 41 ( Suppl. 2 S120 S126.
46. Kerry J. Coyne R. Gilroy D. Hiney M. Smith P. ( 1996) Spatial distribution of oxytetracycline and elevated frequencies of oxytetracycline resistance in sediments beneath a marine salmon farm following oxytetracycline therapy. Aquaculture 145 : 31 39.
47. Kim E.H. Aoki T. ( 1993) Drug resistance and broad geographical distribution of identical R plasmids of Pasteurella piscicida isolated from cultured yellowtail in Japan. Microbiol Immunol 37 : 103 109.
48. Kim S.-R. Nonaka L. Suzuki S. ( 2004) Occurrence of tetracycline resistance genes tet(M) and tet(S) in bacteria from marine aquaculture sites. FEMS Microbiol Lett 237 : 147 156.
49. Kruse H. Sørum H. ( 1994) Transfer of multiple drug resistance plasmids between bacteria of diverse origins in natural microenvironments. Appl Environ Microbiol 60 : 4015 4021.
50. L'Abee-Lund T.M. Sørum H. ( 2001) Class 1 integrons mediate antibiotic resistance in the fish pathogen Aeromonas salmonicida worldwide. Microb Drug Resist 7 : 263 272.
51. Le T.X. Munekage Y. ( 2004) Residues of selected antibiotics in water and mud from shrimp ponds in mangrove areas in Viet Nam. Mar Pollut Bull 49 : 922 929.
52. Le T.X. Munekage Y. Kato S. ( 2005) Antibiotic resistance in bacteria from shrimp farming in mangrove areas. Sci Total Environ 349 : 95 105.
53. Li X.-Z. ( 2005) Quinolone resistance in bacteria: emphasis on plasmid-mediated mechanisms. Int J Antimicrob Agents 25 : 453 463.
54. Lillehaug A. Lunestad B.T. Grave K. ( 2003) Epidemiology of bacterial diseases in Norwegian aquaculture - a description based on antibiotic prescription data for the ten-year period 1991 to 2000. Dis Aquat Org 53 : 115 125.
55. McDermott P.F. Zhao S. Wagner D.D. Simjee S. Walker R.D. White D.G. ( 2002) The food safety perspective of antibiotic resistance. Anim Biotechnol 13 : 71 84.
56. Markestad A. Grave K. ( 1997) Reduction of antibacterial drug use in Norwegian fish farming due to vaccination. Fish Vaccinol 90 : 365 369.
57. Miranda C.D. Zemelman R. ( 2001) Antibiotic resistant bacteria in fish from the Concepcion Bay, Chile. Mar Pollut Bull 42 : 1096 1102.
58. Miranda C.D. Zemelman R. ( 2002a) Bacterial resistance to oxytetracycline in Chilean salmon farming. Aquaculture 212 : 31 47.
59. Miranda C.D. Zemelman R. ( 2002b) Antimicrobial multiresistance in bacteria isolated from freshwater Chilean salmon farms. Sci Total Environ 293 : 207 218.
60. Miranda C.D. Kehrenberg C. Ulep C. Schwarz S. Roberts M.C. ( 2003) Diversity of tetracycline resistance genes in bacteria from Chilean salmon farms. Antimicrob Agents Chemother 47 : 883 888.
61. Moellering R.C., Jr ( 2005) The fluoroquinolones: the last Samurai? Clin Infect Dis 41 ( Suppl. 2 S111 S112.
62. Nandi S. Maurer J.J. Hofacre C. Summers A.O. ( 2004) Gram-positive bacteria are a major reservoir of Class 1 antibiotic resistance integrons in poultry litter. Proc Natl Acad Sci USA 101 : 7118 7122.
63. Naylor R. Burke M. ( 2005) Aquaculture and ocean resources: raising tigers of the sea. Annu Rev Environ Resources 30 : 185 218.
64. Naylor R.L. Goldburg R.J. Primavera J.H. Kautsky N. Beveridge M.C.M. Clay J., et al. ( 2000) Effect of aquaculture on world fish supplies. Nature 405 : 1017 1024.
65. Naylor R.L. Eagle J. Smith W.L. ( 2003) Salmon aquaculture in the Pacific Northwest. A global industry with local impacts. Environment 45 : 18 39.
66. Nordmann P. Poirel L. ( 2005) Emergence of plasmid-mediated resistance to quinolones in Enterobacteriaceae. J Antimicrob Chemother 56 : 463 469.
67. Petersen A. Andersen J.S. Kaewmak T. Somsiri T. Dalsgaard A. ( 2002) Impact of integrated fish farming on antimicrobial resistance in a pond environment. Appl Environ Microbiol 68 : 6036 6042.
68. Poirel L. Liard A. Rodriguez-Martinez J.-M. Nordmann P. ( 2005a) Vibrionaceae as a possible source of Qnr-like quinolone resistance determinants. J Antimicrob Chemother 56 : 1118 1121.
69. Poirel L. Rodriquez-Martinez J.-M. Mammeri H. Liard A. Nordmann P. ( 2005b) Origin of plasmid-mediated quinolone resistance determinant QnrA. Antimicrob Agents Chemother 49 : 3523 3525.
70. Rhodes G. Huys G. Swings J. McGann P. Hiney M. Smith P. Pickup R.W. ( 2000a) Distribution of oxytetracycline resistance plasmids between aeromonads in hospital and aquaculture environments: implication of Tn1721 in dissemination of the tetracycline resistance determinant Tet A. Appl Environ Microbiol 66 : 3883 3890.
71. Rhodes L.D. Grayson T.H. Alexander S.M. Strom M.S. ( 2000b) Description and characterization of IS994, a putative IS3 family insertion sequence from the salmon pathogen, Renibacterium salmoninarum. Gene 244 : 97 107.
72. Roberts M.C. ( 2005) Update on acquired tetracycline resistance genes. FEMS Microbiol Lett 245 : 195 203.
73. Robicsek A. Sahm D.F. Strahilevitz J. Jacoby G.A. Hooper D.C. ( 2005) Broader distribution of plasmid-mediated quinolone resistance in the United States. Antimicrob Agents Chemother 49 : 3001 3003.
74. Robicsek A. Strahilevitz J. Jacoby G.A. Macielag M. Abbanat D. Park C.H., et al. ( 2006) Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase. Nature Med 12 : 83 88.
75. Saga T. Kaku M. Onodera Y. Yamachika S. Sato K. Takase H. ( 2005) Vibrio parahaemolyticus chromosomal qnr homologue VPA0095: demonstration by transformation with a mutated gene of its potential to reduce quinolone susceptibility in Escherichia coli. Antimicrob Agents Chemother 49 : 2144 2145.
76. Salyers A.A. Gupta A. Wang Y. ( 2004) Human intestinal bacteria as reservoirs for antibiotic resistance genes. Trends Microbiol 12 : 412 416.
77. Samuelsen O.B. Lunestad B.T. Husevag B. Holleland T. Ervik A. ( 1992) Residues of oxolinic acid in wild fauna following medication in fish farms. Dis Aquat Org 12 : 111 119.
78. Samuelsen O.B. Lunestad B.T. Ervik A. Fjeldes S. ( 1994) Stability of antibacterial agents in an artificial marine aquaculture sediment studied under laboratory conditions. Aquaculture 126 : 283 290.
79. Sandaa R.-A. Enger Ø. ( 1994) Transfer in marine sediments of the naturally occurring plasmid pRAS1 encoding multiple antibiotic resistance. Appl Environ Microbiol 60 : 4234 4238.
80. Schmidt A.S. Bruun M.S. Dalsgaard I. Pedersen K. Larsen J.L. ( 2000) Occurrence of antimicrobial resistance in fish-pathogenic and environmental bacteria associated with four Danish rainbow trout farms. Appl Environ Microbiol 66 : 4908 4915.
81. Schmidt A.S. Bruun M.S. Dalsgaard I. Larsen J.L. ( 2001a) Incidence, distribution, and spread of tetracycline resistance determinants and integron-associated antibiotic resistance genes among motile aeromonads from a fish farming environment. Appl Environ Microbiol 67 : 5675 5682.
82. Schmidt A.S. Bruun M.S. Larsen J.L. Dalsgaard I. ( 2001b) Characterization of class 1 integrons associated with R-plasmids in clinical Aeromonas salmonicida isolates from various geographical areas. J Antimicrob Chemother 47 : 735 743.
83. Sellner K.G. Doucette G.J. Kirkpatrick G.J. ( 2003) Harmful algal blooms: causes, impacts and detection. J Ind Microbiol Biotechnol 30 : 383 406.
84. Sørum H. ( 1998) Mobile drug resistance genes among fish bacteria. APMIS 106 ( Suppl. 84 74 76.
85. Sørum H. ( 2000) Farming of Atlantic salmon - an experience from Norway. Acta Vet Scand Suppl. 93 : 129 134.
86. Sørum H. ( 2006) Antimicrobial drug resistance in fish pathogens. In Antimicrobial Resistance in Bacteria of Animal Origin. Aarestrup F.M. (ed.). Washington, DC, USA : American Society for Microbiology Press, pp. 213 238 (Chapter 13).
87. Sørum H. L'Abée-Lund T.M. ( 2002) Antibiotic resistance in food-related bacteria - a result of interfering with the global web of bacterial genetics. Int J Food Microbiol 78 : 43 56.
88. Valiela I. ( 1995) Long-term and large-scale change in marine ecosystems. In Marine Ecological Processes, 2nd edn. New York, NY, USA : Springer-Verlag New York, pp. 499 544 (Chapter 16).
89. Wang H. Dzink-Fox J.L. Chen M. Levy S.B. ( 2001) Genetic characterization of highly fluoroquinolone-resistant clinical Escherichia coli strains from China: role of acrR mutations. Antimicrob Agents Chemother 45 : 1515 1521.
90. Weber J.T. Mintz E.D. Canizares R. Semiglia A. Gomez I. Sempertegui R., et al. ( 1994) Epidemic cholera in Ecuador: multidrug-resistance and transmission by water and seafood. Epidemiol Infect 112 : 1 11.
91. Wegener H.C. ( 1999) The consequences for food safety of the use of fluoroquinolones in food animals. N Engl J Med 340 : 1581 1582.
92. Wierup M. ( 2001) The Swedish experience of the 1986 year ban of antimicrobial growth promoters, with special reference to animal health, disease prevention, productivity, and usage of antimicrobials. Microb Drug Resist 7 : 183 190.
93. Witte W. ( 2000) Selective pressure by antibiotic use in livestock. Int J Antimicrob Agents 16 : S19 S24.